Search results for "Colon"

showing 10 items of 2038 documents

Photocrosslinking of dextran and polyaspartamide derivatives: a combination suitable for colon-specific drug delivery.

2007

Abstract The aim of this study was to prepare and characterize novel hydrogels with polysaccharide–polyaminoacid structure, able to undergo an enzymatic hydrolysis in the colon and potentially useful for treating inflammatory bowel diseases (IBD). Starting materials were methacrylated dextran (DEX-MA) and methacrylated α,β-poly(N-2-hydroxyethyl)- dl -aspartamide (PHM). These polymers were photocrosslinked by exposure of their aqueous solutions at 313 nm without photoinitiators. Different samples, shaped as microparticles, were obtained as a function of polymer concentration and irradiation time. FT-IR analysis confirmed the occurrence of a co-crosslinking between DEX-MA and PHM in all exper…

alpha; beta-poly(n-2-hydroxyethyl)-dl-aspartamide; biodegradable hydrogels; colon drug delivery; dextran; photocrosslinking; α; β-poly(n-2-hydroxyethyl)-dl-aspartamidealphaCell SurvivalColonPhotochemistryDrug CompoundingαPharmaceutical ScienceDosage formchemistry.chemical_compoundDrug StabilityEnzymatic hydrolysismedicineCell AdhesionOrganic chemistryHumansParticle Sizeβ-poly(n-2-hydroxyethyl)-dl-aspartamideDrug CarriersChromatographyDextranaseAqueous solutionChemistryHydrolysisbiodegradable hydrogelstechnology industry and agriculturecolon drug deliveryBeclomethasoneMucinsDextransHydrogelsHydrogen-Ion ConcentrationDextranCross-Linking Reagentsbeta-poly(n-2-hydroxyethyl)-dl-aspartamidedextranDrug deliverySelf-healing hydrogelsMethacrylatesSwellingmedicine.symptomphotocrosslinkingCaco-2 CellsPeptidesJournal of controlled release : official journal of the Controlled Release Society
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Colonial, post-colonial, neo-colonial Mediterranean: historical, archaeological and iconographical sources for a micro-history of an uncomfortable th…

2020

Even in its most neutral meanings, the term “colonial” leads to questioning the cultural and ideological purpose of its use. This also concerns its derivatives, post-colonial and neo-colonial, whose prefixes are not to be interpreted in a merely chronological sense. This paper investigates the remote origins of a mental attitude that has resulted both in a “colonial” reading of some phenomena and in a post-colonial new interpretation. The aim is to highlight the common cultural bases of these two very different conceptions (in theory opposite and non-superimposable). Also, the interpretations which are apparently far from imperialism are not totally immune from the danger of a form of racis…

ancient colonialism coloniality racism Romanization post-colonial archaeology cooperationSettore L-ANT/07 - Archeologia Classica
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Unconditional adoption rules out the need for parent–offspring recognition in a single‐brooded colonial seabird

2021

Parent–offspring recognition (POR) is fundamental in colonial birds when the potential intermingling of chicks is higher due to the large number and proximity of nests. In species with isolated nests, where chick presence in the nest is strong contextual evidence of kinship, there might be circumstances when the parent might doubt the identity of the chick, but not enough to reject it. Olfactory-based recognition of conspecifics and nest sites in birds has gained strong evidence suggesting a potential role of olfaction in POR. Despite that, there are no studies testing it. We used Scopoli's shearwater (Calonectris diomedea) as model colonial single-brooded species with a developed olfactory…

animal structuresKin recognitionBiologyParent offspringColonialismKin recognitionScopoli's shearwaterbiology.animalembryonic structuresCross-fosteringCross-fosteringAnimal Science and ZoologySeabirdEcology Evolution Behavior and SystematicsDemographyEthology
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Role of the microbiota in the defense against infections by Enterococci

2017

Resumen de la Tesis : “Role of the microbiota in the defense against infections by Enterococci” Introducción El tracto gastrointestinal está colonizado por centenares de especies de bacterias comensales. Se ha visto en los últimos años que dichas bacterias presentan un papel crucial en la prevención y resolución de enfermedades infecciosas. La microbiota comensal inhibe a patógenos oportunistas mediante mecanismos (i) de interacción directa, por producción de sustancias inhibitorias o competición por nutrientes (ii) indirectos, por la inducción del sistema inmune. El tratamiento con antibióticos altera la composición de la microbiota intestinal promoviendo la colonización intestinal por pat…

antibiotic resistanceenterococcusvremicrobiologyvancomycinUNESCO::CIENCIAS DE LA VIDAmicrobiotaintestinal colonization:CIENCIAS DE LA VIDA [UNESCO]
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Arquitectura marítima de Puerto Rico, en los Siglos XVI-XVIII

2015

La siguiente investigación realizada para completar el grado doctoral en Historia del Arte y Cultura Visual fue establecida en el contexto arquitectónico ultraterritorial, en la proyección de los aspectos históricos, funcionales, eclécticos e institucionales de la empresa Ibérica en las Américas. Se fundamenta la implicación de apostar a través de la creación el destino de una potencia y territorios ultramarinos; concepto que no lleva explícitamente el de Historia del Arte, pero está vinculado. A través de crónicas, testimonios y documentos por los cuales se revelan las motivaciones por las que fueron construidas las estructuras marítimas de abastionamiento marítimo particularmente en funci…

antillasUNESCO::CIENCIAS DE LAS ARTES Y LAS LETRAScaribeUNESCO::HISTORIA:CIENCIAS DE LAS ARTES Y LAS LETRAS [UNESCO]:HISTORIA [UNESCO]arquitecturacolonia españolapuerto rico
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Smad7 controls resistance of colitogenic T cells to regulatory T cell-mediated suppression.

2008

Background & Aims Foxp3-expressing regulatory T cells (Tregs) play a key role in the maintenance of the gut immune homeostasis, and an intact transforming growth factor (TGF)-β signaling is required for their function. In inflammatory bowel disease (IBD), the TGF-β signaling is impaired because of high expression of the inhibitory molecule Smad7. Although no intrinsic defects in Tregs function have been shown in IBD, it is still unknown whether colitogenic T cells are susceptible to Treg-mediated suppression. In this study, we have investigated whether IBD mucosal CD4+ T cells are resistant to Tregs and whether Smad7 is involved in this process. Methods IBD lamina propria mononuclear cells …

antisense oligonucleotideCD4-Positive T-LymphocytesAdoptive cell transferT-Lymphocytesanimal cellCell CommunicationInbred C57BLT-Lymphocytes RegulatoryTransgenicMiceregulatory T lymphocyteCrohn DiseaseTransforming Growth Factor betamononuclear cellRAG1 proteinIntestinal MucosaenteritisCells CulturedMice KnockoutSettore MED/12 - GastroenterologiaCulturedintegumentary systemmedicine.diagnostic_testarticleGastroenterologyInterleukinhemic and immune systemsT helper cellColitisRegulatoryUp-Regulationmedicine.anatomical_structurepriority journalgamma interferonSignal TransductionRegulatory T cellColonCellsKnockoutanimal experimentinterleukin 6chemical and pharmacologic phenomenaMice TransgenicBiologyinterleukin 2Recombination-activating geneFlow cytometryProinflammatory cytokineSmad7 ProteinmedicineAnimalsHumanscontrolled studyhumanlamina propriamouseCell ProliferationHomeodomain ProteinsCD4+ T lymphocytenonhumanHepatologyAnimalflow cytometryhuman cellanimal cell culturetransgenic mouseMice Inbred C57BLDisease Models Animalantisense oligonucleotide; gamma interferon; interleukin 17; interleukin 2; interleukin 6; RAG1 protein; Smad7 protein; animal cell; animal cell culture; animal experiment; article; CD4+ T lymphocyte; cell proliferation; colitis; controlled study; enteritis; flow cytometry; human; human cell; knockout mouse; lamina propria; mononuclear cell; mouse; nonhuman; priority journal; regulatory T lymphocyte; transgenic mouse; Animals; CD4-Positive T-Lymphocytes; Cell Communication; Cell Proliferation; Cells Cultured; Colitis; Colon; Crohn Disease; Disease Models Animal; Homeodomain Proteins; Humans; Intestinal Mucosa; Mice; Mice Inbred C57BL; Mice Knockout; Mice Transgenic; Signal Transduction; Smad7 Protein; T-Lymphocytes Regulatory; Transforming Growth Factor beta; Up-RegulationDisease ModelsImmunologyinterleukin 17knockout mouseTransforming growth factorGastroenterology
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Les Statues meurent aussi? Post-musealizzazione dell'arte coloniale.

2015

Tra il 1950 e il 1953 i cineasti Chris Marker e Alain Resnais girano in Africa e in Francia il documentario Les statues meurent aussi. Commissionato dalla rivista letteraria francese «Présence africaine», il cortometraggio è in aperta polemica con Il museo immaginario della scultura mondiale di André Malraux del 1952. Marker e Resnais, al contrario dello scrittore francese, parlano di un’unità stilistica perduta reintroducendo una triplice divisione all’interno del continuum estetico-formale universale: antropologica, riguardante la separazione tra oggetto museale esposto e pratica contestuale a cui il manufatto rimanda; storica, relativa alla ferita che la colonizzazione ha inferto alle cu…

antropologia arte coloniale museo immaginario post musealizzazione Resnais e MarkerSettore M-DEA/01 - Discipline Demoetnoantropologiche
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La Nueva España a través de la antropología de la muerte (siglos XVI-XVII): el caso de sor Juana Inés de la Cruz

2016

Este proyecto de investigación se focaliza en las costumbres mortuorias y funerarias en la colonia de la Nueva España entre los siglos XVI y XVII, así como los mitos, los ritos, las creencias y las representaciones relacionadas con la muerte. Considerando la hibridez y la diversidad de este fenómeno, se ha decidido seguir parcialmente los estudios de Louis-Vincent Thomas quien, en su libro Antropología de la muerte, analiza conceptos, visiones, divergencias y comportamientos del ser humano ante este acontecimiento. Tras presentar la concepción de la muerte europea y española para entender, en un segundo momento, la referida a las épocas de la Conquista y de la colonia, la tesis se ha dividi…

antropología de la muertecostumbres funerariassor juana inés de la cruzcolonia de la nueva españaexcavaciones san jerónimocostumbres mortuorias
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Artico nero. La lunga notte dei popoli dei ghiacci

2016

Sette storie da un Artico nero e morente, ambientate in Canada, nella Norvegia settentrionale, in Siberia, in Groenlandia: luoghi dove la distruzione di una cultura sta anticipando gli scenari peggiori. Un’analisi politica e sociale incassata nel modello romanzo-saggio. Un modo nuovo di raccontare e fare antropologia: antropofiction.

artico geografia polare etnografia colonialismoSettore M-DEA/01 - Discipline DemoetnoantropologicheSettore M-GGR/01 - Geografia
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Égalité et citoyenneté en Algérie et dans les établissements français de l'Inde au milieu du XIXe siècle

2008

Dans les colonies françaises d'Algérie et des établissements de l'Inde du XIXe siècle, la société était totalement différente de celle des « quatre vieilles colonies » : elle comportait des communautés identifiables, avec des droits locaux ; les habitants étaient régis par un statut juridique déterminé en fonction de leur religion. Ces statuts personnels des indigènes – terme pris dans son sens large et non dans celui du code de l'indigénat – étaient incompatibles avec le Code civil sans adaptation. Par ailleurs, l'organisation locale, en castes pour les hindous, en tribus pour l'Algérie, étaient également bien éloignées des institutions françaises. L'acculturation juridique était donc néce…

assimilation[SHS.DROIT] Humanities and Social Sciences/LawCode civilIIe Républiquenationquatre vieilles coloniesassimilationnismeégalité civile et politiqueracisme[ SHS.DROIT ] Humanities and Social Sciences/Lawstatuts personnelsindigènesAlgérie[SHS.DROIT]Humanities and Social Sciences/LawreligionXIXe siècleacculturation juridiqueétablissements de l'Inde
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