Search results for "Colon"
showing 10 items of 2038 documents
EGF Induces STAT3-Dependent VEGF Expression in HT-29 colon cancer cells
2009
Hidden biochemical action of Ethanol on colon carcinoma cell models
Colorectal cancer (CRC) is one of the most widespread cancers in the world. Numerous risk factors have been correlated with the development of CRC, including genetic factors, inflammation, intestinal microflora composition, as well as lifestyle factors, such as smoking, high consumption of red meats and alcohol intake. Epidemiological studies support the conclusion that chronic and heavy alcohol consumption increases the risk to develop CRC as well as favors the progression of this form of cancer. However, the biochemical mechanisms responsible for these events have not yet been fully clarified. The aim of my doctoral project was to study the effects of ethanol in human colorectal carcinoma…
Autophagic cell death induced by Litchi fruit extracts in human colon cancer cells.
2016
Litchi chinensis is a tropical fruit which cultivation has been recently introduced in Sicily. Some findings have shown that Litchi extracts display antitumor effects but the underlying mechanisms have not been elucidated. This study focuses on the effects of Litchi hydro-alcoholic extracts in colorectal cancer cells. The results indicated that Litchi exocarp (peel), mesocarp (pulp) and endocarp (seeds) extracts reduce the viability of HT-29 colon cancer cells in a dose dependent manner. This effect was accompanied with G2/M arrest of the cell cycle followed by cell death. Interestingly, exocarp and endocarp extracts triggered an autophagic response in the first phase of treatment (16-24h) …
Antitumor activity of water extract of pleurotus species growing on root residues against colon cancer cells.
2012
Immunoscore in Mismatch Repair-Proficient and -Deficient Colon Cancer
2017
Abstract The aim of this study was to investigate immune response and its prognostic significance in colon carcinomas using the previously described Immunoscore (IS). A population-based series of 779 colorectal cancers, operated on between 2000 and 2010, were classified according to tumour, node, metastasis (TNM) status, mismatch repair (MMR), and BRAF mutation status. Rectal cancer cases (n = 203) were excluded as a high proportion of these patients received preoperative neoadjuvant chemoradiotherapy. Tissue microarray (TMA) samples collected from the tumour centre and invasive front were immunostained for CD3 and CD8. Lymphocytes were then digitally calculated to categorize IS from grade …
Endurance training induces apoptosis in the tumor mass in the C26-bearing mouse model
2018
Cáncer de colon. Estudio de base poblacional de la aplicación de las gráficas de control CUSUM en el análisis del estado ganglionar
2017
INTRODUCCIÓN. En nuestro medio, el cáncer colorrectal es el tumor maligno más frecuentemente diagnosticado en ambos sexos y representa una de las principales causas de muerte por cáncer. La afectación ganglionar se ha relacionado de una manera directa con la supervivencia y con el intervalo libre de enfermedad. El número total de ganglios analizados, incluso en los pacientes con estadio ganglionar pN0, es un demostrado factor pronóstico. Por lo que los nuevos métodos de estadificación ganglionar, cociente ganglionar (LNR) y logaritmo de odds ganglionar (LODDS), pueden ofrecer ventajas respecto a la clasificación TMN para la obtención de subgrupos de riesgo similar. Las gráficas Cumulative S…
Peripheral motor effects of glucagon-like peptide-1 in mouse intestine.
2008
El stent como puente a la cirugía en la obstrucción maligna de colon. Estudio del impacto oncológico de la perforación relacionada con el stent y de …
2021
El uso del stent como puente a la cirugía en la obstrucción maligna de colon es un motivo actual de controversia y preocupación, debido a los resultados oncológicos a largo plazo observados en algunos estudios recientemente publicados. OBJETIVOS: El objetivo de nuestro estudio fue analizar el impacto de la perforación relacionada con el stent y los cambios anatomopatológicos que ocasiona su colocación en los pacientes candidatos a tratamiento curativo por obstrucción maligna de colon, con el fin de determinar su influencia en los resultados oncológicos a largo plazo. MATERIAL Y MÉTODO: Se llevaron a cabo dos revisiones sistemáticas y metaanálisis según la metodología PRISMA. En el metaanáli…