Search results for "Colon"
showing 10 items of 2038 documents
Gene expression in TGFbeta-induced epithelial cell differentiation in a three-dimensional intestinal epithelial cell differentiation model
2006
Abstract Background The TGFβ1-induced signal transduction processes involved in growth and differentiation are only partly known. The three-dimensional epithelial differentiation model, in which T84 epithelial cells are induced to differentiate either with TGFβ1 or IMR-90 mesenchymal cell-secreted soluble factors, is previously shown to model epithelial cell differentiation seen in intestine. That model has not been used for large scale gene expression studies, such as microarray method. Therefore the gene expression changes were studied in undifferentiated and differentiated three-dimensional T84 cultures with cDNA microarray method in order to study the molecular changes and find new play…
Deconstructing Gendered and Colonial Violence in the Re-Imagined Nineteenth-Century: Domestic Traumas in Neo-Victorianism on Screen
2023
En esta tesis, examinamos el colapso del concepto idealizado de familia nuclear en las sociedades occidentales a través de la (mala) representación de los traumas de género y coloniales en el neovictorianismo audiovisual. Para ello, analizamos cuatro textos audiovisuales neovictorianos producidos en la última década: Crimson Peak (2015) de Guillermo del Toro, Penny Dreadful (2014-2016), Taboo (2017-presente) y Carnival Row (2019-presente) a través del marco teórico de los estudios de trauma. Nuestras hipótesis de partida son (1) estos textos audiovisuales neovictorianos aparentemente proporcionan una representación feminista de los traumas de género dentro de los confines de la familia nucl…
Estudios de Género desde una perspectiva decolonial. Trama y Urdimbre: Tejido de una memoria de mujeres migrantes de Abya Yala como sujetas políticas
2022
La presente investigación se enmarca dentro de la producción académica de los feminismos decoloniales de Abya Yala situados en el Estado español. De esta manera, este escrito trata sobre las memorias de los activismos de un grupo de mujeres migrantes racializadas de Abya Yala que forman parte de diferentes colectivas autónomas y organizaciones formales del ámbito social. Estas mujeres se presentan como sujetas políticas en el territorio valenciano en un contexto que comprende desde finales del siglo XX hasta las dos primeras décadas del siglo XXI, período durante el cual se han entretejido una serie de acontecimientos, datos, sentipensares, lugares de la memoria, símbolos e interpretaciones…
Mesoporous silica microparticles gated with a bulky azo derivative for the controlled release of dyes/drugs in colon.
2018
[EN] Mesoporous silica microparticles were prepared, loaded with the dye safranin O (M-Saf) or with the drug budesonide (M-Bud) and capped by the grafting of a bulky azo derivative. Cargo release from M-Saf at different pH values (mimicking those found in the gastrointestinal tract) in the absence or presence of sodium dithionite (a reducing agent mimicking azoreductase enzyme present in the colon) was tested. Negligible safranin O release was observed at pH 6.8 and 4.5, whereas a moderate delivery at pH 1.2 was noted and attributed to the hydrolysis of the urea bond that linked the azo derivative onto the external surface of the inorganic scaffold. Moreover, a marked release was observed w…
Tree age‐dependent changes among epiphytic bryophyte communities in Mediterranean environments. A case study from Sicily (Italy)
2010
Abstract The epiphytic bryophytes inhabiting trees of different size/age in a Quercus ilex wood from Madonie Mountains (northern Sicily, Italy) were studied with the purpose of describing the changes that take place in the bryophyte stratum during the tree lifespan. Results indicate an increase of bryophyte cover combined with a progressive decrease of epiphytic lichens and the existence of an active process of species and community substitution. The way these processes take place corresponds to a succession sequence, which is characterised by a high number of pioneer species on the youngest trees and a sharp decline of species number on middle‐aged and old trees due to the great spread of …
Nunatak survival vs. tabula rasa in the Central Pyrenees: a study on the endemic plant species Borderea pyrenaica (Dioscoreaceae)
2007
14 páginas, 4 figuras, 2 tablas.
Gender, Identities, and Material Culture in the Italic Peninsula: Burial Practices and Loom Weights in Perspective
2021
AbstractThis paper discusses the complex relationship between material culture and gender studies from a methodological point of view, with the aim of contributing to discussions in the field of Classical archaeology. First, we provide a few historiographical benchmarks for key epistemological developments, while evidencing the methodological difficulties inherent in the variability of our interpretations of burial practices and data. Then, in a second section, a case study focuses on simple objects of daily life. Discussing approaches inspired by gender studies, and considering the place of loom weights, we wish to tackle the presumption of textile work as an eminently female activity. The…
Guanine-based purines affects the enteric cholinergic neurotransmission via a mechanism not involving membrane receptors
2011
Increasing evidence indicate that guanine-based purines, known as modulators of intracellular processes, can exert extracellular effects, raising the possibility of the existence of specific receptors for these compounds. We investigated if guaninebased purine receptors may be present in the rodent gastrointestinal tract modulating intestinal contractility, as the well known adenine-based purine receptors. Experiments were performed in vitro recording spontaneous and neurally-evoked contractile activity, as changes in isometric tension, in mouse distal colon circular muscle. Guanosine up to 3 mM or guanine up to 1 mM, did not affect the spontaneous mechanical activity, but they significantl…
INVOLVEMENT OF GUANINE-BASED PURINES IN THE MODULATION OF CHOLINERGIC TRANSMISSION IN MOUSE COLONIC PREPARATIONS
2010
Modelos de mundo y discursos literarios saboteadores en Guinea Ecuatorial: la construcción de una identidad decolonial y sus límites
2022
Esta investigación parte del interés por analizar la posición ideológica de la literatura escrita por mujeres guineoecuatorianas en la construcción de la identidad nacional decolonial. Guinea Ecuatorial se enfrenta desde su independencia de España en 1968, a una necesaria reconstrucción identitaria que fluctúa entre los legados del colonialismo pasado y la recuperación de sus culturas y valores precoloniales. En ambos casos, la mujer negra y sus discursos ocupan una posición subalterna, ya sea frente al patriarcado de la cultura colonial española o frente al nuevo nacionalismo patriarcal poscolonial. Desde esa posición de negatividad frente al modelo de mundo hegemónico, las voces de ellas …