Search results for "Color"

Imaging standardisation in metastatic colorectal cancer: a joint EORTC-ESOI-ESGAR expert consensus recommendation

2022

Background: Treatment monitoring in metastatic colorectal cancer (mCRC) relies on imaging to evaluate the tumor burden. Response Evaluation Criteria in Solid Tumors (RECIST) provide a framework on reporting and interpretation of imaging findings yet offer no guidance on a standardized imaging protocol tailored to mCRC patients. Imaging protocol heterogeneity remains a challenge for the reproducibility of conventional imaging endpoints and is an obstacle for research on novel imaging endpoints. Patients and methods: Acknowledging the recently highlighted potential of radiomics and artificial intelligence (AI) tools as decision support for patient care in mCRC, a multidisciplinary, internatio…

The dark side of the moon: The PI3K/PTEN/AKT pathway in colorectal carcinoma

2009

Wild-type KRAS status is required but not sufficient to confer sensitivity to anti-epidermal growth factor receptor (EGFR) monoclonal antibodies (mAbs) in colorectal cancer patients. As a consequence, one of the major challenges is to identify, in non-mutant KRAS patients, other markers that can predict lack of response to this therapy. Small series have investigated the clinical effect of PIK3CA mutations on resistance to anti-EGFR mAbs and discrepant results have been observed. Furthermore, PTEN loss in metastases may be predictive of resistance to anti-EGFR mAbs, even if PTEN determination is far from an immediate clinical application. The introduction of modulators of the PI3K/AKT/mTOR …

Evaluation of Franz Marc’s Color Theory using Implicit Testing Procedures

2018

In the early 20th century, the German expressionist painter Franz Marc formulated assumptions concerning the meanings of color, based on his individual sensations. He characterized the ‘cool’ blue as the ‘masculine principle’. Yellow represented the ‘feminine principle’ which he declared as ‘gentle, cheerful, and sensual’. This leaves red, the color he perceived as ‘brutal and heavy’. Here, we tested some of the color–meaning associations assumed by Franz Marc via implicit measures based on response times, using Single Category Implicit Association Tests. The participants had to classify words as belonging to one of two semantic categories (e.g., masculine or feminine) by pressing one of tw…

Palermo bianca

2019

Palermo bianca potrebbe sembrare una città invisibile; e, tuttavia, nonostante le stratificazioni e le trasformazioni, è da annoverare tra le autentiche città bianche, specialmente per essere una delle capitali del Mediterraneo. Il bianco è rintracciabile in alcune tappe della storia della città, confermando le ambigue origini ed i molteplici significati di questo colore. White Palermo may seem like an invisible city; and, however, despite the stratifications and transformations, it is to be counted among the authentic white cities, especially for being one of the capitals of the Mediterranean. White is traceable in some stages of the city's history, confirming the ambiguous origins and mul…

Insights into the Maya Blue technology: greenish pellets from the ancient city of La Blanca.

2011

Financial support is gratefully acknowledged from the MEC Projects CTQ2011-28079-CO3-01 and 02 which are also supported with ERDF funds. Research was conducted within the "Grupo de anlisis cientifico de bienes culturales y patrimoniales y estudios de ciencia de la conservacion" Microcluster of the University of Valencia Excellence Campus. The authors would like to thank Dr. Isabel Solana (SCSIE, UV), Dr. Jose Luis Moya Lopez, and Manuel Planes Insausti (Microscopy Service UPV) for their technical support.

Characterization of foxing stains in early twentieth century photographic and paper materials

2016

The subject of this present work is a group of nine historical pictures shot in Palermo by the Sicilian photographer E. Interguglielmi in 1912. They are nine matte-collodion prints mounted on the original cardboard supports and all of them show foxing stains affecting the paper surface. In order to characterise the chemical composition of the supports and investigate foxing spots, non-destructive and micro-destructive analysis were carried out. X-rays fluorescence (XRF) analysis was used to characterise the elemental composition of all the mounting boards, allowing a comparison between the foxing spots and non-affected areas. Laser-Induced Breakdown Spectroscopy was used to investigate the …

Neuropharmacology of vision in goldfish: A review

2009

AbstractThe goldfish is one of the few animals exceptionally well analyzed in behavioral experiments and also in electrophysiological and neuroanatomical investigations of the retina. To get insight into the functional organization of the retina we studied color vision, motion detection and temporal resolution before and after intra-ocular injection of neuropharmaca with known effects on retinal neurons. Bicuculline, strychnine, curare, atropine, and dopamine D1- and D2-receptor antagonists were used. The results reviewed here indicate separate and parallel processing of L-cone contribution to different visual functions, and the influence of several neurotransmitters (dopamine, acetylcholin…

2020

This work introduces a method to estimate reflectance, shading, and specularity from a single image. Reflectance, shading, and specularity are intrinsic images derived from the dichromatic model. Estimation of these intrinsic images has many applications in computer vision such as shape recovery, specularity removal, segmentation, or classification. The proposed method allows for recovering the dichromatic model parameters thanks to two independent quadratic programming steps. Compared to the state of the art in this domain, our approach has the advantage to address a complex inverse problem into two parallelizable optimization steps that are easy to solve and do not require learning. The p…

Initial conditions in AA and pA collisions

2016

A full understanding of the spacetime evolution of the QCD matter created in a heavy ion collision requires understanding the properties of the initial stages. In the weak coupling picture these are dominated by classical gluon fields, whose properties can also be studied via the scattering of dilute probes off a high energy hadron or nucleus. A particular challenge is understanding small systems, where LHC data is also showing signs of collective behavior. We discuss some recent results of on the initial matter production and thermalization in heavy ion collisions, in particular in the gluon saturation framework.

A model for dark matter, naturalness and a complete gauge unification

2015

We consider dark matter in a minimal extension of the Standard Model (SM) which breaks electroweak symmetry dynamically and leads to a complete unification of the SM and technicolor coupling constants. The unification scale is determined to be $M_{\rm U} \approx 2.2 \times 10^{15}$ GeV and the unified coupling $\alpha_{\rm U} \approx 0.0304$. Moreover, unification strongly suggest that the technicolor sector of the model must become strong at the scale of ${\cal O}$(TeV). The model also contains a tightly constrained sector of mixing neutral fields stabilized by a discrete symmetry. We find the lightest of these states can be DM with a mass in the range $m_{\rm DM} \approx 30-800$ GeV. We f…