Search results for "Color"

Analysis of UGT1A1*28 and DPYD*2A polymorphisms in Sicilians patients with metastatic colorectal cancer treated with Irinotecan and 5-fluorouracil.

2013

DISMICROBISM IN INFLAMMATORY BOWEL DISESE AND COLORECTAL CANCER: CHANGES IN RESPONSE OF COLOCYTES

2014

Patients with inflammatory bowel disease (IBD) have an increased risk of 10%-15% developing colorectal cancer (CRC) that is a common disease of high economic costs in developed countries. the CRC has been increasing in recent years and its mortality rates are very high. Multiple biological and biochemical factors are responsible for the onset nad progression of this pathology. moreover, it appears absolutely necessary to investigate the environmental factors favoring the onset of CRC and the production of colonic healt. the gut microflora, or microbiota, has an extensive diversity both quantitatively and qualitatively. in utero, the intestine of the mammalian fetus is sterile. Al birth, the…

Expression of angiogenic regulators. VEGF and leptin, is regulated by the EGF/P13K/STAT3 pathway in colorectal cancer cells

2009

Myeloid zinc finger 1 regulates thymidylate synthase expression in patients with metastatic colorectal cancer showing the same promoter gene polymorp…

2011

Le razze umane non esistono, lo dimostra…. il colore della pelle!

2015

Alcune manifestazioni fenotipiche della specie umana sono tramandate di generazione in generazione secondo delle regole che apparentemente non seguono le classiche leggi di Mendel: sono i caratteri continui, un tipo particolare di ereditarietà in cui ha molta influenza l’ambiente ed anche le sue interazioni con il genoma. Solo per questi tipi particolari di caratteri è possibile definire due grandezze, l’ereditabilità e la varianza, che danno una misura di quanta sia la componente genetica e di quanto quella ambientale nella loro definizione. Studi di correlazione fra persone non imparentate e gemelli monozigoti hanno dimostrato che il carattere continuo umano “creste digitali” ha un alto v…

Streptomyces coelicolor extracellular vesicles

This study may reveal the importance of extracellular vesicles in the physiology of S. coelicolor and may also have important biotechnological implications.

Graphene oxide containing hyaluronic acid based nanogels for the potential treatment of colorectal cancer

2017

Here, we reported the production of graphene oxide (GO) containing nanogels produced by a top-down procedure employing as a starting biomaterial an amino derivative of hyaluronic acid named HA-EDA. This derivative was reacted, in the presence of single layer GO, with α,β-poly(N-2-hydroxyethyl)-D,L-aspartamide-((2-aminoethyl)-carbamate)-divinyl sulfone (PHEA-DVS) employed as a macromolecular crosslinking agent. The so obtained hydrogel was homogenized by ultra-turrax and high pressure homogenizer and nanogels with Z-average of 390 nm and PDI of 0.22 were obtained. These nanogels were employed to incorporate Irinotecan (IT), an antitumor drug used in the treatment of colorectal carcinoma. It …

Role of the Colored Noise in Spatio-Temporal Behavior of Two Competing Species

2005

We study the spatial distributions of two randomly interacting species, in the presence of an external multiplicative colored noise. The dynamics of the ecosystem is described by a coupled map lattice model. We find a nonmonotonic behavior in the formation of large scale spatial correlations as a function of the multiplicative colored noise intensity. This behavior is shifted towards higher values of the noise intensity for increasing correlation time of the noise.

Role of the colored noise in a FitzHugh-Nagumo system driven by a periodic signal

2007

During these last years the interest in neuronal dynamics increased. The study of this kind of system has been carried out by using the FitzHugh-Nagumo (FHN) model that is a simplified modification of the Hodgkin-Huxley model. Many interesting phenomena can be observed in the presence of fluctuations: modification of detection threshold by manipulation of noisy parameters (FHN model), noise-induced activation and coeherence resonance for suitable noise amplitude (absence of periodic signal), resonant activation for high periodic signals and noise reduction, intrinsic stochastic resonance (ISR) in Hodgkin-Huxley neuron and the enhancement of a weak signal by tuning the subthreshold intrinsic…

ANALISI DEI MECCANISMI DI RIATTIVAZIONE DI UN’AREA IN FRANA NEL BACINO DEL FIUME IMERA SETTENTRIONALE

2022

Al fine di valutare le condizioni limite per la stabilità di un pendio in frana, sono state svolte delle analisi di stabilità all’equilibrio limite 2D e 3D in un’area ubicata nel bacino del fiume Imera Settentrionale (Sicilia). Tali analisi hanno permesso di ricostruire un modello geologico e geotecnico ottimale, di individuare il livello piezometrico che ha determinato le condizioni di instabilità e di definire i parametri operativi di resistenza a taglio dei terreni. Le recenti riattivazioni dei meccanismi di frana hanno fornito elementi che hanno permesso di validare in particolare i risultati delle analisi numeriche 3D. I risultati ottenuti hanno anche evidenziato che il metodo di anali…