Search results for "Comet"

showing 10 items of 274 documents

Synthesis and solution properties of star-shaped poly(tert-butyl acrylate)

2000

A series of star polymers consisting of poly(tert-butyl acrylate) arms and an ethyleneglycol dimethacrylate (EGDMA) microgel core were synthesized using anionic polymerization. The effect of various parameters (precursor length, ratio [[EGDMA]/[Initiator], reaction time, and overall concentrations) on the average number of arms was investigated. Molecular weights were determined using GPC coupled with an online viscometer and MALLS. The exponents for the relation between intrinsic viscosity or radius of gyration and molecular weight, respectively, are extremely low, indicating that the dimensions of the star polymers only slightly increase with the number of arms. After a certain number of …

AcrylateTert-butyl acrylateMaterials sciencePolymers and PlasticsMolecular massIntrinsic viscosityOrganic ChemistryViscometerStar (graph theory)Condensed Matter PhysicsCondensed Matter::Soft Condensed Matterchemistry.chemical_compoundAnionic addition polymerizationchemistryPolymer chemistryMaterials ChemistryRadius of gyrationPhysical chemistryAstrophysics::Galaxy AstrophysicsMacromolecular Symposia
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How Do Religiosity and Spirituality Associate with Health-Related Outcomes of Adolescents with Chronic Illnesses? A Scoping Review.

2022

The aim of the current scoping review was to explore the associations between religious and spiritual factors and the health-related outcomes of adolescents with chronic illnesses, as well as to investigate possible mechanisms accounting for these relationships. In total, 20 studies meeting the eligibility criteria were reviewed after performing a search of the Scopus, Web of Science, and PubMed databases. The results suggested that religious and spiritual beliefs, thoughts, and practices (e.g., spiritual coping activities) might have both beneficial and deleterious effects on the way adolescents deal with their medical condition, on their psychosocial adjustment, on their mental and physic…

AdolescentHealth Toxicology and MutagenesisadjustmentPublic Health Environmental and Occupational HealthSettore M-PSI/03 - Psicometriareligiosity; spirituality; adolescence; chronic illness; adjustmentreligiosityReligionSettore M-PSI/04 - Psicologia Dello Sviluppo E Psicologia Dell'EducazioneAdaptation PsychologicalChronic DiseaseHumansadolescenceSpiritualitychronic illnessInternational journal of environmental research and public health
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Development of a Brief Form of the Interpersonal Reactivity Index (B–IRI)

2016

ABSTRACTThe Interpersonal Reactivity Index (IRI) is a standardized self-report measure of disposition to empathic responsiveness for the general adult population (the domain for which it was developed), and for the general adolescent population. The IRI has a number of problems, however, including some uncertainty about its factor structure, low reliabilities, and poor readability of some items for people with limited literacy skills. To address these issues, we constructed an abbreviated form of the index, the Brief IRI (B–IRI). Three studies demonstrated that this 16-item B–IRI has a clear and coherent factor structure, adequate internal consistency, measurement invariance across gender a…

Adult050103 clinical psychologyIndex (economics)AdolescentPsychometricsHealth Toxicology and MutagenesisAdult population050109 social psychologyPersonality Assessmenturologic and male genital diseasesFactor structureDevelopmental psychologyArts and Humanities (miscellaneous)HumansInterpersonal Relations0501 psychology and cognitive sciencesMeasurement invariancecardiovascular diseasesClinical Psychology; Arts and Humanities (miscellaneous)urogenital systemfungi05 social sciencesSettore M-PSI/03 - PsicometriaReproducibility of ResultsConstruct validityDispositionfemale genital diseases and pregnancy complicationsReadabilityClinical PsychologyInterpersonal Reactivity IndexEmpathyPsychologyIRI brief form development measurement invariance confirmatory factor analysis validity construct
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Induction of heme oxygenase-1 and adaptive protection against the induction of DNA damage after hyperbaric oxygen treatment.

2000

Hyperbaric oxygen (HBO) treatment of human subjects (i.e. exposure to 100% oxygen at a pressure of 2.5 ATA for a total period of 3 x 20 min) caused clear and reproducible DNA damage in lymphocytes, as detected with the comet assay (single cell gel electrophoresis). Induction of DNA damage was found only after the first HBO exposure and not after further treatments of the same individuals. Furthermore, blood taken 24 h after HBO treatment was significantly protected against the induction of DNA damage by hydrogen peroxide (H(2)O(2)) in vitro, indicating that adaptation occurred due to induction of antioxidant defenses. The cells were not significantly protected against the genotoxic effects …

AdultCancer ResearchDNA RepairDNA repairDNA damageCarbon-Oxygen LyasesBiologymedicine.disease_causeSuperoxide dismutasemedicineDNA-(Apurinic or Apyrimidinic Site) LyaseHumansLymphocytesDNA Polymerase betachemistry.chemical_classificationReactive oxygen speciesHyperbaric OxygenationSuperoxide DismutaseMembrane ProteinsGeneral MedicineHydrogen PeroxideCatalaseMolecular biologyDNA-(apurinic or apyrimidinic site) lyaseAdaptation PhysiologicalDeoxyribonuclease IV (Phage T4-Induced)Comet assayOxidative StresschemistryBiochemistryCatalaseEnzyme InductionHeme Oxygenase (Decyclizing)biology.proteinOxidative stressHeme Oxygenase-1DNA DamageCarcinogenesis
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Emotional expression and coping style in female breast cancer.

2007

Background: The study of the relationship of emotional status and tumor etiology has been investigated in order to elaborate a multifactorial model able to provide an answer integrating the different disciplines on cancer. The aim of this work is to investigate the knowledge on the alexithymia construct, exploring the presence of such trait in women affected by mammary carcinoma and analyzing the used coping strategies. The study has also examined personal thoughts related to event control (locus of control). Method: The Toronto Alexithymia Scale, Coping Orientation to Problems Experienced, and Locus of Control questionnaires were administered to a group of 86 women aged 31-55 years (mean =…

AdultCoping (psychology)medicine.medical_specialtySettore MED/06 - Oncologia Medicabreast cancer psychological aspectDysfunctional familyBreast NeoplasmsToronto Alexithymia ScaleBreast cancerAlexithymiaAdaptation PsychologicalMedicineHumansEmotional expressionAffective Symptomsmedicine.diagnostic_testbusiness.industrySettore M-PSI/03 - PsicometriaHematologyMiddle Agedmedicine.diseaseSurgeryExpressed EmotionLocus of controlOncologyEtiologyFemalebusinessClinical psychology
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Associations Among Psychologically Controlling Parenting, Autonomy, Relatedness, and Problem Behaviors During Emerging Adulthood.

2017

ABSTRACTThe present study aimed to investigate the relations among perceived parental psychological control (PPC), autonomy and relatedness, and negative outcomes during emerging adulthood in two cultural contexts: Italy and the USA. More specifically, we explored the mechanisms through which dependency-oriented PPC (DPPC) and achievement-oriented PPC (APPC) are associated with both internalizing and externalizing difficulties, focusing on the mediating role of autonomy and relatedness. Participants were 418 European-American and 359 Italian college students. Results indicated that the expressions of PPC with regard to dependency and achievement were related to emerging adults’ negative out…

AdultCross-Cultural ComparisonMaleParentsPsychology (all)genetic structuresAdolescent3304media_common.quotation_subjectCodependency PsychologicalEthnic groupPsychological intervention050109 social psychologyPersonal autonomyEducationDevelopmental psychologySettore M-PSI/04 - Psicologia Dello Sviluppo E Psicologia Dell'EducazioneYoung AdultPsychological controlHumansBusiness0501 psychology and cognitive sciencesYoung adultParent-Child RelationsGeneral Psychologymedia_commonCross-cultural differenceParentingdevelopmental issues05 social sciencesSettore M-PSI/03 - PsicometriaCross-cultural differences; developmental issues; parenting; 3304; Business Management and Accounting (miscellaneous); Psychology (all)developmental issueCross-cultural studiesUnited StatesCross-cultural differencesThiazolesPersonal AutonomyBusiness Management and Accounting (miscellaneous)FemaleManagement and Accounting (miscellaneous)PsychologyAutonomy050104 developmental & child psychologyClinical psychologyThe Journal of psychology
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Task and Ego Orientation in Sport Questionnaire (TEOSQ): Psychometric properties in its digital version

2022

The Task and Ego Orientation in Sport Questionnaire’s (TEOSQ’s) psychometric properties have been explored in previous studies but never in its digital version, which facilitates data collection. The objective of this study was to analyze the psychometric properties of the online TEOSQ by MenPas 1.0. The sample was composed of 2320 users (58.4% women; 41.6% men), between 18 and 65 years old (M = 25.27, SD = 7.39). The methods used were Confirmatory Factor Analysis (CFA) and invariance analysis from the original 13-item model. The CFA was corrected for all samples (CFI = 0.92–0.94, TLI = 0.93–0.95, RMSEA = 0.07, SRMR = 0.06; df = 64; Bollen-Stine Bootstrap p = 0.02–0.07): general sample (χ2 …

AdultEgoMaleEsportsAdolescentPsychometricsPsicologia socialHealth Toxicology and MutagenesisInvariancePublic Health Environmental and Occupational HealthReproducibility of ResultsMiddle AgedAchievement goalsPsychometric propertiesYoung AdultSurveys and QuestionnairesPsicometríaHumansFemaleachievement goals; sport; invariance; psychometric propertiesFactor Analysis StatisticalSportAged
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Assessment of the cytotoxic potential of an aqueous-ethanolic extract from Thalassia testudinum angiosperm marine grown in the Caribbean Sea

2018

Abstract Objectives Reported antioxidant, anti-inflammatory and neuroprotective properties for one aqueous-ethanolic extract from Thalassia testudinum which grows in the Caribbean Sea compelled us to explore about extract cytotoxic effects. Methods Cell viability was assayed on tumour (HepG2, PC12, Caco-2 and 4T1) and non-tumour (VERO, 3T3, CHO, MCDK and BHK2) cell lines. The extract effects upon primary cultures of rat and human hepatocytes and human lymphocytes were assayed. Key findings The extract exhibited cytotoxicity against cancer cells compared to normal cells, and the IC50 values were 102 μg/ml for HepG2, 135 μg/ml for PC12, 165 μg/ml for Caco-2 and 129 μg/ml for 4T1 cells after 4…

AdultMale0301 basic medicineCell SurvivalDNA damagePrimary Cell CulturePharmaceutical ScienceHydrocharitaceaePC12 CellsRats Sprague-DawleyInhibitory Concentration 5003 medical and health sciencesNeoplasmsAnimalsHumansCytotoxic T cellLymphocytesViability assayCytotoxicityPharmacologyDose-Response Relationship DrugEthanolbiologyPlant ExtractsChemistryPharmacology. TherapyWaterHep G2 Cellsbiology.organism_classificationAntineoplastic Agents PhytogenicMolecular biologyRatsComet assay030104 developmental biologyCaribbean RegionCell cultureThalassia testudinumCancer cellSolventsCaco-2 CellsThalassia testudinum DNA damage cytotoxicity oxidative stressJournal of pharmacy and pharmacology
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Blood levels of nitric oxide and DNA breaks assayed in whole blood and isolated peripheral blood mononucleated cells in patients with multiple sclero…

2019

Abstract Oxidative stress, especially overproduction of nitric oxide (NO), is considered to be one of the crucial factors in the pathogenesis of multifactorial multiple sclerosis (MS). DNA breaks could be one of the consequences of oxidative stress; however, data on DNA breakage in MS are very few and contradictory. There are no data on direct measurements of NO production in the blood of MS patients. The goal of this study was to determine the level of single-stranded DNA breaks in whole blood or isolated peripheral blood mononuclear cells (PBMNCs) by means of alkaline single cell gel electrophoresis (comet assay) and to evaluate production of NO in the human blood by applying electron par…

AdultMale0301 basic medicineMultiple SclerosisDNA damageHealth Toxicology and Mutagenesis010501 environmental sciencesNitric Oxidemedicine.disease_cause01 natural sciencesPeripheral blood mononuclear cellNitric oxide03 medical and health scienceschemistry.chemical_compoundGeneticsmedicineHumansDNA Breaks Single-StrandedAged0105 earth and related environmental sciencesWhole bloodGel electrophoresisChemistryMultiple sclerosisElectron Spin Resonance SpectroscopyMiddle Agedmedicine.diseaseMolecular biologyComet assay030104 developmental biologyLeukocytes MononuclearFemaleComet AssaySingle-Cell AnalysisOxidative stressDNA DamageMutation Research/Genetic Toxicology and Environmental Mutagenesis
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Propiedades psicométricas de la Escala de Quejas Somáticas en niños y adultos españoles

2015

The aim of this study was to analyse the psychometric properties of the Somatic Complaints List (SCL) in Spanish child and adult populations. This instrument assesses the frequency with which people experience and feel pain such as stomach ache and headache, among others. It has been validated in different countries and languages (Dutch, English, and Persian), showing adequate psychometric properties. Nevertheless, it has never been validated in a Spanish context. Method: For the adaptation and validation, we used two different samples: 1423 children, age ranging from 8 to 12 years old, selected from 12 primary and secondary schools at 7 locations in the Valencian Community, Spain (age = 9.…

AdultMaleAdolescentPsychometricsmoodEmotionsPsychology ChildSpanishSeverity of Illness IndexSomatizacionesNociceptive PainYoung AdultSurveys and QuestionnairesHumansespañolChildquejas somáticasvalidationSomatic complaintsMétodo de evaluaciónReproducibility of ResultsMiddle AgedTranslatingSpainvalidaciónestados de ánimoPsicometríaFemaleSymptom AssessmentDolor
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