Search results for "Complex."
showing 10 items of 5824 documents
Endothelin receptors mediating contraction in goat cerebral arteries
1993
1. The aim of the present study was to identify the subtype of receptor mediating contraction to endothelin-1 and sarafotoxin S6b in goat isolated middle cerebral arteries. 2. Endothelin-1, endothelin-2 and endothelin-3 contracted cerebral arteries in a concentration-dependent manner. Although the three peptides were full agonists, the order of potency was endothelin-1 = endothelin-2 > endothelin-3, with a relative potency of endothelin-1 and endothelin-2 versus endothelin-3 of approximately 280. Sarafotoxin S6b induced concentration-dependent contractions with lower potency than endothelin-1/endothelin-2, higher potency than endothelin-3 and a higher maximum response than the three endothe…
Fibroblast Growth Factor Receptor 1– 5-Hydroxytryptamine 1A Heteroreceptor Complexes and Their Enhancement of Hippocampal Plasticity
2011
Background The hippocampus and its 5-hydroxytryptamine transmission plays an important role in depression related to its involvement in limbic circuit plasticity. Methods The analysis was made with bioluminescence resonance energy transfer, co-immunoprecipitation, in situ proximity ligation assay, binding assay, in cell western and the forced swim test. Results Using bioluminescence resonance energy transfer analysis, fibroblast growth factor receptor 1 (FGFR1)-5-hydroxytryptamine 1A (5-HT1A) receptor complexes have been demonstrated and their specificity and agonist modulation characterized. Their presence based on co-immunoprecipitation and proximity ligation assay has also been indicated…
Increase of the FGFR1 signaling in the FGFR1-5-HT1A heteroreceptor complex in midbrain raphe 5-HT neuron systems via allosteric receptor-receptor int…
2015
The ascending midbrain 5-HT neurons known to contain 5-HT1A autoreceptors may be dysregulated in depression due to a reduced trophic support. New findings show existence of FGFR1-5-HT1A heteroreceptor complexes in the rat hippocampus with a partial characterization of their interface and in midbrain raphe 5-HT nerve cells. With in situ Proximity Ligation Assay (PLA) and supported by co-location of the FGFR1 and 5-HT1A immunoreactivities in midbrain raphe 5-HT cells, evidence for the existence of FGFR1-5-HT1A heteroreceptor complexes were obtained in the dorsal and median raphe nuclei of the Sprague–Dawley rat. Their existence in the rat medullary raphe RN33B cell cultures was also establish…
Coupling and Complexity of Interaction of STCA Networks
2009
This paper provides an overview on the results of an ENAV feasibility study, where we exploited an automatic safety data gathering tool to analyze the ATM system performances. In particular, it addresses the use of the EUROCONTROL tool, ASMT (Automatic Safety Monitoring Tool), as a support to monitor STCA performance. The contribution of this study is to explore how analysis methods derived from complex systems theory (i.e. network analysis) can assist in the understanding, monitoring and management of the performance of ATM systems. Our data show that a large number of STCAs do not occur in isolation, but rather that in roughly half of the cases the aircraft involved in an STCA are subsequ…
Complex Networks in Air Transport
2016
The application of CNT to air traffic management has seen significant growth in recent years. This is partly because air traffic can be seen as the superposition of different networks, including the networks of airports, sectors and navigation points. Moreover each of these networks can be seen as a multiplex – for example, by associating each layer with a different airline. The study of the topology of these networks is important for several reasons related to understanding, monitoring, controlling, and optimising the air traffic system. The topological properties of air traffic networks are useful: (i) for studying how the air traffic has changed in recent years; (ii) for identifying the …
Selective recovery of phosphorus as AlPO4 from silicon-free CFB-derived fly ash leachate
2018
The prospect of phosphorus (P) recovery from siliceous fly ash was investigated. The phosphorus content in the pristine fly ash was 1.21%. Obtaining pure phosphorus products from fly ash is very challenging because of high concentration of other elements, silicon (Si) at 17.3% being the major contaminant. The fly ash was fractionated with sieve size of 125 μm to concentrate the phosphorus in the small-size fraction, which also facilitated the removal of 78% of silica (Si) in the solid phase. The fractionated fly ash was treated with 8 M HCl in order to remove 98% of Si by aging (5 h) of leachate until precipitation of Si-gel, and a phosphorus-rich solution is obtained. Iron (Fe) is also con…
Synthesis, characterization of diorganotin(IV) complexes of N-(2-hydroxyarylidene)aminoacetic acid and antitumour screening in vivo in ehrlich ascite…
2001
Some new diorganotin(IV) complexes have been prepared by reacting potassium N-(2-hydroxyarylidene)aminoacetate with R2SnCl2(R = Me,nBu,Ph). The complexes have been characterized by 1H,13C,119Sn NMR, IR and 119mSn Mössbauer spectroscopic techniques in combination with elemental analysis. In the solid state, the complexes possess penta- and hexa-coordinated tin centres. The hexa-coordinated tin complexes were found to dissociate in solution, giving rise to penta-coordinated species as revealed by 119Sn NMR spectroscopy. Antitumour screening in vivo of the complexes L4snPh2,L4SnPh2· Ph3SnCl and L4SntBU2·t Bu2SnCl2 (L4 = N-(2-hydroxyacetophenone)aminoacetate) is also reported. Copyright © 2001 …
Complex multiplication, Griffiths-Yukawa couplings, and rigidity for families of hypersurfaces
2003
Let M(d,n) be the moduli stack of hypersurfaces of degree d > n in the complex projective n-space, and let M(d,n;1) be the sub-stack, parameterizing hypersurfaces obtained as a d fold cyclic covering of the projective n-1 space, ramified over a hypersurface of degree d. Iterating this construction, one obtains M(d,n;r). We show that M(d,n;1) is rigid in M(d,n), although the Griffiths-Yukawa coupling degenerates for d<2n. On the other hand, for all d>n the sub-stack M(d,n;2) deforms. We calculate the exact length of the Griffiths-Yukawa coupling over M(d,n;r), and we construct a 4-dimensional family of quintic hypersurfaces, and a dense set of points in the base, where the fibres ha…
A note on cocharacter sequence of Jordan upper triangular matrix algebra
2016
Let UJn(F) be the Jordan algebra of n × n upper triangular matrices over a field F of characteristic zero. This paper is devoted to the study of polynomial identities satisfied by UJ2(F) and UJ3(F). In particular, the goal is twofold. On one hand, we complete the description of G-graded polynomial identities of UJ2(F), where G is a finite abelian group. On the other hand, we compute the Gelfand–Kirillov dimension of the relatively free algebra of UJ2(F) and we give a bound for the Gelfand–Kirillov dimension of the relatively free algebra of UJ3(F).
Relative principal congruences in congruence-modular quasivarieties
1998
The problem of definability of relative principal congruences in relatively congruence modular (RCM) quasivarieties is investigated. The RCM quasivarieties are characterized in terms of parameterized families of finite sets of pairs of terms which define relative principal congruences.