Search results for "Complications."

showing 10 items of 1514 documents

Proteinuria-Lowering Effects of Proprotein Convertase Subtilisin/Kexin Type 9 Inhibitors in Chronic Kidney Disease Patients: A Real-World Multicentri…

2021

Control of dyslipidemia in chronic kidney disease (CKD) is not always guaranteed with statins and/or ezetimibe. Proprotein convertase subtilisin/kexin type 9 inhibitors (PCSK9i) have opened up a new era in lipid control, but their effect on renal function and proteinuria in real life have not yet been evaluated. The aim of the present study was to analyze the evolution of renal function and proteinuria in a cohort of CKD patients treated with PCSK9i. This retrospective multicentric cohort study included CKD patients treated with PCSK9i. Baseline epidemiological data, comorbidities and laboratory findings (including estimated glomerular filtration rate [eGFR], proteinuria and lipid profile) …

medicine.medical_specialtyEndocrinology Diabetes and MetabolismUrologyRenal functionurologic and male genital diseasesMicrobiologyBiochemistryArticleNephrotoxicitychemistry.chemical_compoundEzetimibePCSK9iCKDmedicinekidney functionMolecular BiologyCreatinineProteinuriamedicine.diagnostic_testbusiness.industrymedicine.diseaseQR1-502female genital diseases and pregnancy complicationschemistryInsuficiència renal crònicaproteinuriamedicine.symptomLipid profilebusinessDyslipidemiaKidney diseasemedicine.drugMetabolites
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Outcomes of monopolar versus bipolar endometrial ablation on uterine bleeding and psychophysical wellbeing.

2017

Background To compare outcomes of endometrial ablation with monopolar versus bipolar resection on uterine bleeding and psychophysical wellbeing. Methods In a prospective randomized study, 100 perimenopausal patients, without desire of pregnancy and with no response to pharmacological treatment, underwent endometrial ablation from 2012 to 2014. They were randomly divided in two groups: 50 patients treated with monopolar electrode resection loop (group A) and 50 patients treated with bipolar electrode resection loop (group B). Operative parameters were immediately assessed. Menstrual outcome parameters and psycho-physical well-being parameters were evaluated after 12 months. Results No signif…

medicine.medical_specialtyEndometrial ablation techniquemedicine.medical_treatmentElectrodeOperative TimeHysteroscopy030204 cardiovascular system & hematologyResectionlaw.invention03 medical and health sciences0302 clinical medicinePostoperative ComplicationsRandomized controlled triallawmedicineHumansProspective randomized studyProspective StudiesProspective cohort studyElectrodesEndometrial Ablation TechniquesPregnancybusiness.industryUterine bleedingObstetrics and GynecologyMiddle Agedmedicine.diseaseSurgeryPerimenopauseProspective StudieTreatment OutcomePremenopause030220 oncology & carcinogenesisEndometrial ablationFemalePostoperative ComplicationUterine HemorrhageComplicationbusinessHumanMinerva ginecologica
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Human papilloma virus genotypes in dysplasia and epithelial hyperplasia of oral cavity using the luminex xmap technology. A multicenter study

2019

Background Oral cancer associated with high risk (HPV-HR) human papilloma virus (HPV) has been increasing. HPV-HR has been associated with epithelial dysplasia, however, little information exists on its frequency in epithelial hyperplasia lesions. The aim of this study is to compare HPV genotypes in dysplastic and hyperplastic lesions of oral cavity. Material and Methods Two hundred and fifty oral lesions: 131 dysplasia and 119 hyperplasia from two regions of Colombia were evaluated. One hundred seventy-four coming from urban area and 104 from a high risk population to oral cancer from a rural area. HPV was identified by qPCR and Twenty-four HPVs genotypes were evaluated by Luminex® technol…

medicine.medical_specialtyEpithelial dysplasiaGenotypePopulationEpithelial dysplasiaGastroenterology03 medical and health sciences0302 clinical medicineEpithelial hyperplasiaInternal medicineGenotypeEnsayo clínicomedicineHumansPapillomaviridaeeducationPapillomaviridaeGeneral DentistryOral Dysplasiaeducation.field_of_studyOral Medicine and PathologyHyperplasiabiologybusiness.industryResearchPapillomavirus InfectionsCancervirus diseasesElectroforesis en gel bidimensional030206 dentistryHyperplasiamedicine.diseasebiology.organism_classification:CIENCIAS MÉDICAS [UNESCO]female genital diseases and pregnancy complicationsEnfermedades de la bocaOtorhinolaryngologyDysplasiaUNESCO::CIENCIAS MÉDICASSurgeryHPV-genotypesbusiness
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Technical details of the abdominal part during full robotic-assisted minimally invasive esophagectomy

2020

Abstract The full robotic-assisted minimally invasive esophagectomy (RAMIE) is an upcoming approach in the treatment of esophageal and junctional cancer. Potential benefits are seen in angulated precise maneuvers in the abdominal part as well as in the thoracic part, but due to the novelty of this approach the optimal setting of the trocars, the instruments and the operating setting is still under debate. Hereafter, we present a technical description of the ‘Mainz technique’ of the abdominal part of RAMIE carried out as Ivor Lewis procedure. Postoperative complication rate and duration of the abdominal part of 100 consecutive patients from University Medical Center in Mainz are illustrated.…

medicine.medical_specialtyEsophageal NeoplasmsRobotic assistedbusiness.industryGeneral surgeryGastroenterologyPostoperative complicationGeneral MedicineEsophagectomy03 medical and health sciencesEsophagusPostoperative Complications0302 clinical medicineRobotic Surgical Procedures030220 oncology & carcinogenesisAbdomenInvasive esophagectomyHumansIvor lewisMedicine030211 gastroenterology & hepatologyUniversity medicalbusinessDiseases of the Esophagus
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Robot-assisted and conventional minimally invasive esophagectomy are associated with better postoperative results compared to hybrid and open transth…

2021

BACKGROUND Currently 4 surgical techniques are performed for transthoracic esophagectomy (open esophagectomy (OE), hybrid esophagectomy (HE), conventional minimally invasive esophagectomy (MIE) and robot assisted minimally invasive esophagectomy (RAMIE). Aim of this study was to compare these 4 different esophagectomy approaches regarding postoperative complications and short term oncologic outcomes. METHODS Between 2008 and 2019, consecutive patients who underwent esophagectomy with gastric conduit reconstruction were included in this single center study. The primary outcome of this study was the incidence of postoperative complications. RESULTS Overall 422 patients (OE (n = 107), HE (n = …

medicine.medical_specialtyEsophageal Neoplasmsmedicine.medical_treatmentTransthoracic esophagectomySingle CenterRamiePostoperative ComplicationsInvasive esophagectomymedicineHumansMinimally Invasive Surgical ProceduresLymph nodebusiness.industryIncidence (epidemiology)General MedicineRoboticsEsophageal cancermedicine.diseaseSurgeryEsophagectomymedicine.anatomical_structureTreatment OutcomeOncologyEsophagectomySurgerybusinessEuropean journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
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Preoperative chemoradiotherapy for oesophageal cancer: a systematic review and meta-analysis

2004

Background: The benefit of neoadjuvant chemoradiotherapy in oesophageal cancer has been extensively studied but data on survival are still equivocal. Objective: To assess the effectiveness of chemoradiotherapy followed by surgery in the reduction of mortality in patients with resectable oesophageal cancer. Methods: Computerised bibliographic searches of MEDLINE and CANCERLIT (1970–2002) were supplemented with hand searches of reference lists. Study selection: Studies were included if they were randomised controlled trials (RCTs) comparing preoperative chemoradiotherapy plus surgery with surgery alone, and if they included patients with resectable histologically proven oesophageal cancer wit…

medicine.medical_specialtyEsophageal Neoplasmsmedicine.medical_treatmentlaw.inventionPostoperative ComplicationsRandomized controlled triallawChemotherapyHumansMedicineEsophageal NeoplasmAdjuvantRandomized Controlled Trials as TopicIntention-to-treat analysisRadiotherapybusiness.industryMortality rateGastroenterologyCancerOdds ratiomedicine.diseaseChemotherapy Adjuvant; Esophageal Neoplasms; Esophagectomy; Humans; Postoperative Complications; Radiotherapy Adjuvant; Randomized Controlled Trials; Survival Analysis; Treatment OutcomeSurvival AnalysisSurgeryEsophagectomyRadiation therapyOesophagusTreatment OutcomeChemotherapy AdjuvantEsophagectomyRandomized Controlled TrialChemotherapy; Adjuvant; Esophageal Neoplasms; Esophagectomy; Humans; Postoperative Complications; Radiotherapy; Randomized Controlled Trials as Topic; Survival Analysis; Treatment OutcomeRadiotherapy AdjuvantPostoperative ComplicationSurvival AnalysibusinessChemoradiotherapyHumanGut
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Gastroesophageal reflux in young children treated for esophageal atresia: evaluation with pH-multichannel intraluminal impedance

2011

Objectives: Gastroesophageal reflux (GER) and dismotility occur frequently after repair of esophageal atresia (EA). GER-associated complications can manifest either early or later; then precocious diagnosis and treatment are essential. The aim of the study was to evaluate characteristics of GER and esophageal clearance in children treated for EA with distal tracheoesophageal fistula, using pH-multichannel intraluminal impedance (pH-MII). Patients and Methods: Twenty-two children (ages 3‐40 months) treated for EA at birth, and 20 normal children of similar age with suspected GER disease were included in the study. Impedance parameters were analyzed according to age and symptoms. Results: Ref…

medicine.medical_specialtyEsophageal pH MonitoringTracheoesophageal fistulaSettore MED/42 - Igiene Generale E ApplicataGastroenterologyGastric AcidEsophagusPostoperative ComplicationsBolus (medicine)Internal medicinemedicineHumansEsophagusGastrointestinal TransitEsophageal Atresiaesophageal atresia esophageal dismotility gastroesophageal reflux disease multichannel intraluminal impedance ph-metryEsophageal diseasebusiness.industryfungiSignificant differenceSettore MED/20 - Chirurgia Pediatrica E InfantileGastroenterologyRefluxInfantHydrogen-Ion Concentrationmedicine.diseasemedicine.anatomical_structureEl NiñoCase-Control StudiesChild PreschoolAtresiaPediatrics Perinatology and Child HealthGastroesophageal RefluxbusinessTracheoesophageal Fistula
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Evidence-based Guidelines for the Management of Exocrine Pancreatic Insufficiency After Pancreatic Surgery

2016

Objective: To provide evidence-based recommendations for the management of exocrine pancreatic insufficiency (EPI) after pancreatic surgery. Background: EPI is a common complication after pancreatic surgery but there is certain confusion about its frequency, optimal methods of diagnosis, and when and how to treat these patients. Methods: Eighteen multidisciplinary reviewers performed a systematic review on 10 predefined questions following the GRADE methodology. Six external expert referees reviewed the retrieved information. Members from Spanish Association of Pancreatology were invited to suggest modifications and voted for the quantification of agreement. Results: These guidelines analyz…

medicine.medical_specialtyEvidence-based practicediagnosisMEDLINEGuidelines030230 surgeryGastroenterologyPancreatic surgerysurgery03 medical and health sciencesPostoperative Complications0302 clinical medicineInternal medicineparasitic diseasesmedicineHumansGuidelines Management Exocrine Pancreatic Insufficiency Pancreatic SurgerypancreasguidelinesExocrine pancreatic insufficiencyPancreatic SurgeryConfusionpancreatic exocrine insufficiencyEvidence-Based Medicinetreatmentbusiness.industryPancreatic DiseasesEvidence-based medicinemedicine.diseaseManagementSurgerySpainpancreaticPractice Guidelines as TopicExocrine Pancreatic Insufficiency030211 gastroenterology & hepatologySurgerymedicine.symptomComplicationOptimal methodsbusinessAnnals of Surgery
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A 2013 European survey of clinical practice patterns in the management of Graves' disease

2014

SummaryObjective Management of Graves' disease (GD) in Europe was published in 1987. Aim of this survey was to provide an update on clinical practice in Europe, and to compare it with a 2011 American survey. Design Members of the European Thyroid Association (ETA) were asked to participate in a survey on management of GD, using the same questionnaire of a recent American survey. Results A total of 147 ETA members participated. In addition to serum TSH and free T4 assays, most respondents would request TSH-receptor autoantibody (TRAb) measurement (85·6%) and thyroid ultrasound (70·6%) to confirm aetiology, while isotopic studies were selected by 37·7%. Antithyroid drug (ATD) therapy was the …

medicine.medical_specialtyExacerbationEndocrinology Diabetes and MetabolismGraves' diseaseThyrotropin030209 endocrinology & metabolismTrabDisease03 medical and health sciences0302 clinical medicineEndocrinologyAntithyroid AgentsPregnancySurveys and QuestionnairesInternal medicinemedicineHumansPractice Patterns Physicians'AutoantibodiesPregnancyMethimazolebusiness.industryThyroidReceptors Thyrotropinmedicine.diseaseGraves DiseaseEuropePregnancy ComplicationsThyroxineEndocrinologymedicine.anatomical_structurePropylthiouracil030220 oncology & carcinogenesisNorth AmericaEtiologyFemalePropylthiouracilbusinessmedicine.drugClinical Endocrinology
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High performance liquid chromatography analysis of tear protein patterns in diabetic and non-diabetic dry-eye patients.

2001

To analyze and compare the high performance liquid chromatography (HPLC) runs of tear proteins from diabetic (DIDRY) and non-diabetic (DRY) dry-eye patients, and healthy subjects (CTRL). The patterns were analyzed using multivariate statistical methods.Tears (total 56 eyes: CTRL: n=16, DIDRY: n=21, and DRY: n=19) were analyzed by HPLC, using a size-exclusion column with an eluent of 0.5 M sodium phosphate buffer. The patients were primarily grouped according to the results of the basic secretory test (BST) in combination with subjective symptoms such as burning, foreign body sensations, tearing, and "dryness" of the eyes. Patients with BST valuesor = 10 mm/5 min plus two subjective symptoms…

medicine.medical_specialtyEye diseaseTear proteinsHigh-performance liquid chromatographyDiabetes Complications03 medical and health sciences0302 clinical medicineOphthalmologyDiabetes mellitusDiabetes MellitusMedicineHumansEye ProteinsChromatography High Pressure Liquidbusiness.industryHealthy subjectsGeneral Medicinemedicine.diseaseeye diseasesSurgeryOphthalmologyTearsMultivariate Analysis030221 ophthalmology & optometryChromatography GelTearsDry Eye Syndromessense organsbusiness030217 neurology & neurosurgeryNon diabeticEuropean journal of ophthalmology
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