Search results for "Compounds"

showing 10 items of 3372 documents

Recombinant laccase from Pediococcus acidilactici CECT 5930 with ability to degrade tyramine

2017

Biogenic amines degradation by bacterial laccases is little known, so we have cloned and heterologously expressed, in E. coli, a new laccase from Pediococcus acidilactici CECT 5930 (Lpa5930), a lactic acid bacterium commonly found in foods able to degrade tyramine. The recombinant enzyme has been characterized by physical and biochemical assays. Here we report the optimization of expression and purification procedures of this laccase. DNA encoding sequence of laccase from P. acidilactici was amplified by PCR and cloned into the expression plasmid pET28a for induction by isopropyl-β-D-thiogalactoipyranoside. Protein expression was performed in E. coli BL21(DE3) harboring pGro7 plasmid expres…

0106 biological sciences0301 basic medicineArabinoseMolecular biologylcsh:MedicineLaccasesBiochemistryBiotecnologia01 natural sciencesSubstrate Specificitylaw.inventionDatabase and Informatics Methodschemistry.chemical_compoundlawRecombinant Protein PurificationCloning MolecularAmineslcsh:Sciencechemistry.chemical_classificationMultidisciplinaryABTSbiologyOrganic CompoundsTemperatureHydrogen-Ion ConcentrationTyramineRecombinant ProteinsEnzymesChemistryRecombination-Based AssayBiochemistryPhysical SciencesRecombinant DNAElectrophoresis Polyacrylamide GelOxidation-ReductionSequence AnalysisResearch ArticleProtein PurificationBioinformaticsTyramineLibrary ScreeningDNA constructionResearch and Analysis Methods03 medical and health sciencesBacterial ProteinsSequence Motif Analysis010608 biotechnologyAmino Acid SequenceBenzothiazolesPediococcus acidilacticiLaccaseMolecular Biology Assays and Analysis TechniquesBase SequenceMolecular massLaccaseOrganic Chemistrylcsh:RChemical CompoundsBiology and Life SciencesProteinsPediococcus acidilacticiSequence Analysis DNAbiology.organism_classificationMolecular biology techniques030104 developmental biologyEnzymechemistryPlasmid ConstructionEnzymologySpectrophotometry Ultravioletlcsh:QSulfonic AcidsEnzimsProteïnesPurification TechniquesPLOS ONE
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Ocean acidification at a coastal CO2 vent induces expression of stress-related transcripts and transposable elements in the sea anemone Anemonia viri…

2019

Published version, available at: https://doi.org/10.1371/journal.pone.0210358 Ocean acidification threatens to disrupt interactions between organisms throughout marine ecosystems. The diversity of reef-building organisms decreases as seawater CO2 increases along natural gradients, yet soft-bodied animals, such as sea anemones, are often resilient. We sequenced the polyA-enriched transcriptome of adult sea anemone Anemonia viridis and its dinoflagellate symbiont sampled along a natural CO2 gradient in Italy to assess stress levels in these organisms. We found that about 1.4% of the anemone transcripts, but only ~0.5% of the Symbiodinium sp. transcripts were differentially expressed. Processe…

0106 biological sciences0301 basic medicineAtmospheric ScienceMolecular biologyMarine and Aquatic SciencesGene ExpressionRetrotransposonSea anemone01 natural sciencesAnemoniaSequencing techniquesMobile Genetic ElementsMultidisciplinarybiologyQREukaryotaOcean acidificationAnemoneRNA sequencingGenomicsChemistryRetrotransposonsPhysical SciencesMedicineTranscriptome AnalysisResearch ArticleScienceZoology010603 evolutionary biology03 medical and health sciencesGreenhouse GasesCnidariaGenetic ElementsSea WaterGeneticsVDP::Matematikk og Naturvitenskap: 400::Basale biofag: 470Environmental ChemistryAnimalsMarine ecosystemBiology and life sciencesEcology and Environmental SciencesDinoflagellateChemical CompoundsOrganismsTransposable ElementsCorrectionAquatic EnvironmentsComputational BiologyCarbon Dioxidebiology.organism_classificationGenome AnalysisMarine EnvironmentsInvertebratesVDP::Mathematics and natural science: 400::Basic biosciences: 470Research and analysis methods:Genetikk og genomikk: 474 VDP::Marinbiologi:497 VDP::Økologi:488 [VDP]030104 developmental biologySea AnemonesMolecular biology techniquesAtmospheric ChemistryEarth SciencesSeawater
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Ultraviolet radiation accelerates photodegradation under controlled conditions but slows the decomposition of senescent leaves from forest stands in …

2019

Depending on the environment, sunlight can positively or negatively affect litter decomposition, through the ensemble of direct and indirect processes constituting photodegradation. Which of these processes predominate depends on the ecosystem studied and on the spectral composition of sunlight received. To examine the relevance of photodegradation for litter decomposition in forest understoreys, we filtered ultraviolet radiation (UV) and blue light from leaves of Fagus sylvatica and Bettda pendula at two different stages of senescence in both a controlled-environment experiment and outdoors in four different forest stands (Picea abies, Pagus sylvatica, Acer platanoides, Betula pendula). Co…

0106 biological sciences0301 basic medicineCanopyUltraviolet RaysPhysiologyUV-B RADIATIONPlant ScienceForestsANTHOCYANINS01 natural sciencesUV radiationBOREAL FOREST03 medical and health scienceschemistry.chemical_compoundFagus sylvaticaPhotodegradationGeneticsPhotodegradationEcosystemFinlandComputingMilieux_MISCELLANEOUS11832 Microbiology and virologyFlavonoidsSunlight[SDV.EE]Life Sciences [q-bio]/Ecology environment4112 ForestryPhotolysisbiologyChemistryTEMPERATEPLANT LITTERPicea abies15. Life on landPlant litterbiology.organism_classificationPhenolic compoundsUnderstorey light environmentSODANKYLAPlant LeavesHorticultureLIGHT030104 developmental biology13. Climate actionBetula pendulaChlorophyllPATTERNS1182 Biochemistry cell and molecular biologyLEAF-LITTER DECOMPOSITION010606 plant biology & botany
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How water-soluble chlorophyll protein extracts chlorophyll from membranes.

2020

Water-soluble chlorophyll proteins (WSCPs) found in Brassicaceae are non-photosynthetic proteins that bind only a small number of chlorophylls. Their biological function remains unclear, but recent data indicate that WSCPs are involved in stress response and pathogen defense as producers of reactive oxygen species and/or Chl-regulated protease inhibitors. For those functions, WSCP apoprotein supposedly binds Chl to become physiologically active or inactive, respectively. Thus, Chl-binding seems to be a pivotal step for the biological function of WSCP. WSCP can extract Chl from the thylakoid membrane but little is known about the mechanism of how Chl is sequestered from the membrane into the…

0106 biological sciences0301 basic medicineChlorophyllCircular dichroismHot Temperaturemedicine.medical_treatmentBiophysicsmacromolecular substances01 natural sciencesBiochemistryLepidiumThylakoids03 medical and health scienceschemistry.chemical_compoundpolycyclic compoundsmedicineBinding sitePlant Proteinschemistry.chemical_classificationReactive oxygen speciesProteasefood and beveragesMembrane ProteinsWaterCell BiologyAmino acid030104 developmental biologyMembraneBiochemistrychemistrySolubilityThylakoidChlorophyll010606 plant biology & botanyBiochimica et biophysica acta. Biomembranes
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The Combined Effects of Ethylene and MeJA on Metabolic Profiling of Phenolic Compounds in Catharanthus roseus Revealed by Metabolomics Analysis

2016

Phenolic compounds belong to a class of secondary metabolites and are implicated in a wide range of responsive mechanisms in plants triggered by both biotic and abiotic elicitors. In this study, we approached the combinational effects of ethylene and MeJA (methyl jasmonate) on phenolic compounds profiles and gene expressions in the medicinal plant Catharanthus roseus. In virtue of a widely non-targeted metabolomics method, we identified a total of 34 kinds of phenolic compounds in the leaves, composed by 7 C6C1-, 11 C6C3-, and 16 C6C3C6 compounds. In addition, 7 kinds of intermediates critical for the biosynthesis of phenolic compounds and alkaloids were identified and discussed with phenol…

0106 biological sciences0301 basic medicineEthylenePhysiologyMetabolitePlant Sciencephenolic compoundsBiology01 natural sciencesCinnamic acid03 medical and health scienceschemistry.chemical_compoundMetabolomicsmethy jasmonatePhysiology (medical)ethyleneOriginal ResearchMethyl jasmonateCatharanthus roseusJasmonic acidCatharanthus roseusbiology.organism_classification030104 developmental biologychemistryBiochemistrynon-targeted metabolomicsSalicylic acid010606 plant biology & botanyFrontiers in Physiology
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Novel mutations in the voltage-gated sodium channel of pyrethroid-resistant Varroa destructor populations from the Southeastern USA

2016

The parasitic mite Varroa destructor has a significant worldwide impact on bee colony health. In the absence of control measures, parasitized colonies invariably collapse within 3 years. The synthetic pyrethroids tau-fluvalinate and flumethrin have proven very effective at managing this mite within apiaries, but intensive control programs based mainly on one active ingredient have led to many reports of pyrethroid resistance. In Europe, a modification of leucine to valine at position 925 (L925V) of the V. destructor voltage-gated sodium channel was correlated with resistance, the mutation being found at high frequency exclusively in hives with a recent history of pyrethroid treatment. Here,…

0106 biological sciences0301 basic medicineInsecticidesVeterinary medicineGene Identification and Analysislcsh:MedicineMicrobiologiaVoltage-Gated Sodium ChannelsFlumethrinmedicine.disease_causeBiochemistry01 natural sciencesAbellesInsecticide Resistancechemistry.chemical_compoundMethioninePyrethrinsÀcarsDestructorAmino Acidslcsh:ScienceMitesMutationMultidisciplinaryPyrethroidbiologyOrganic CompoundsGeneral MedicineBeesSoutheastern United StatesInsectsChemistryPhysical SciencesInsect ProteinsGeneral Agricultural and Biological SciencesResearch ArticleArthropodaApiaryParàsitsVarroidaeGeneral Biochemistry Genetics and Molecular Biology03 medical and health sciencesLeucineparasitic diseasesGeneticsMitemedicineAnimalsPoint MutationSulfur Containing Amino AcidsIsoleucineMutation DetectionAllelesbusiness.industryPoint mutationOrganic Chemistrylcsh:ROrganismsChemical CompoundsBiology and Life SciencesProteinsbiology.organism_classificationInvertebratesHymenopteraBiotechnology010602 entomology030104 developmental biologyAliphatic Amino AcidschemistryGenetic LociVarroa destructorMutationlcsh:Qbusiness
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Biotechnological Applications for the Sustainable Use of Marine By-products: In Vitro Antioxidant and Pro-apoptotic Effects of Astaxanthin Extracted …

2019

In this study, the carotenoid astaxanthin was obtained by supercritical fluid extraction (SFE) from shrimp by-products (SBP). Its bioactive properties were evaluated in vitro in human normal and cancerous cells lines. The antioxidant activity of the extracted astaxanthin of the SFE fraction (ASTA) was tested in fibroblast cells (HS-68), by inducing oxidative stress and by evaluating the protective effect of the pre-treatment with different levels of ASTA against toxicity. The anti-proliferative activity was evaluated in hepatoma cells (HEP-G2), treated with increased concentrations of ASTA and measuring the effects on vitality and on some biomolecular markers related to oxidative stress, ce…

0106 biological sciences0301 basic medicineMarine bioactive compoundAntioxidantmedicine.medical_treatmentBiologymedicine.disease_causeSupercritical fluid extraction01 natural sciencesApplied Microbiology and Biotechnology03 medical and health scienceschemistry.chemical_compoundNutraceuticalSettore AGR/20 - ZoocoltureAstaxanthin010608 biotechnologymedicineFood scienceSettore BIO/06 - Anatomia Comparata E CitologiaCarotenoidchemistry.chemical_classificationAnti-proliferativeAstaxanthinApoptosiMarine bioactive compounds Astaxanthin Supercritical fluid extraction Antioxidants Anti-proliferative Apoptosis030104 developmental biologychemistryCell cultureApoptosisToxicityAntioxidantOxidative stressMarine Biotechnology
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Hexanoic Acid Treatment Prevents Systemic MNSV Movement in Cucumis melo Plants by Priming Callose Deposition Correlating SA and OPDA Accumulation

2017

Unlike fungal and bacterial diseases, no direct method is available to control viral diseases. The use of resistance-inducing compounds can be an alternative strategy for plant viruses. Here we studied the basal response of melon to Melon necrotic spot virus (MNSV) and demonstrated the efficacy of hexanoic acid (Hx) priming, which prevents the virus from systemically spreading. We analysed callose deposition and the hormonal profile and gene expression at the whole plant level. This allowed us to determine hormonal homeostasis in the melon roots, cotyledons, hypocotyls, stems and leaves involved in basal and hexanoic acid-induced resistance (Hx-IR) to MNSV. Our data indicate important roles…

0106 biological sciences0301 basic medicineMelonsalicylic acidPlant Sciencelcsh:Plant culture01 natural sciencesHypocotylMicrobiologyOPDA03 medical and health scienceschemistry.chemical_compoundCucumis meloPlant viruslcsh:SB1-1110Original ResearchHexanoic acidPriming by natural compoundsbiologyMelon necrotic spot virusCallosefood and beveragesSalicylic acidbiology.organism_classificationpriming by natural compounds030104 developmental biologychemistryBiochemistryMNSVhexanoic acidHexanoic acidCucumisSalicylic acid010606 plant biology & botany
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Ammonium acts systemically while nitrate exerts an additional local effect on Medicago truncatula nodules

2020

National audience; Symbiotic nitrogen fixation (SNF) has a high energetic cost for legume plants; legumes thus reduce SNF when soil N is available. The present study aimed to increase our understanding regarding the impacts of the two principal forms of available N in soils (ammonium and nitrate) on SNF. We continuously measured the SNF of Medicago truncatula under controlled conditions. This permitted nodule sampling for comparative transcriptome profiling at points connected to the nodules' reaction following ammonium or nitrate applications. The N component of both ions systemically induced a rhythmic pattern of SNF, while the activity in control plants remained constant. This rhythmic a…

0106 biological sciences0301 basic medicinePlant Sciencenodule activity01 natural sciencesNicotianamine synthaseTranscriptome03 medical and health scienceschemistry.chemical_compoundNitratenitrateRNA seqAmmonium CompoundsMedicago truncatulaGeneticsAmmoniumLeghemoglobinSymbiosisLegumeNitratesbiologyNCR peptidesfungiGeneral MedicineneNASbiology.organism_classificationMedicago truncatula030104 developmental biologychemistryBiochemistrynitrogen fixation[SDE]Environmental SciencesNitrogen fixationbiology.proteinRoot Nodules PlantAgronomy and Crop Science010606 plant biology & botany
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An integrated proteomic and metabolomic study to evaluate the effect of nucleus-cytoplasm interaction in a diploid citrus cybrid between sweet orange…

2018

Key message: Our results provide a comprehensive overview how the alloplasmic condition might lead to a significant improvement in citrus plant breeding, developing varieties more adaptable to a wide range of conditions. Abstract: Citrus cybrids resulting from somatic hybridization hold great potential in plant improvement. They represent effective products resulting from the transfer of organelle-encoded traits into cultivated varieties. In these cases, the plant coordinated array of physiological, biochemical, and molecular functions remains the result of integration among different signals, which derive from the compartmentalized genomes of nucleus, plastids and mitochondria. To dissect …

0106 biological sciences0301 basic medicineProteomicsCitrusCytoplasmCitruProtoplast fusionCybridPlant ScienceProteomicsDisaccharides01 natural sciencesGenomeMass SpectrometryDisaccharideCitrus spp.Electrophoresis Gel Two-DimensionalCell NucleuChromatography High Pressure LiquidCitrus sinensiPlant ProteinsGeneticsChromatography Reverse-Phasefood and beveragesPlant ProteinGeneral MedicineVolatile organic compoundGlucuronateProteomePloidyPlant LeaveCitrus sinensisBreeding programMetabolomicGlucuronatesStomatal conductanceBiology03 medical and health sciencesMetabolomicsGeneticGeneticsMetabolomicsPlant breedingPlastidCitrus sppCell NucleusVolatile Organic CompoundsfungiProteomicDiploidyPlant LeavesPlant Breeding030104 developmental biologyAgronomy and Crop Science010606 plant biology & botanyPlant molecular biology
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