Search results for "Computer Science Application"
showing 10 items of 3998 documents
Hospital performance: Efficiency or quality? Can we have both with IT?
2015
This paper explores influence of IT investment on hospital efficiency and quality.There is a direct effect of IT investment on service quality in hospitals.There is a moderating effect of quality on operational efficiency in hospitals.There is a U-shaped relationship between IT investments and operational efficiency.IT investments have diminishing returns beyond a certain point. The influence of IT investment on hospital efficiency and quality are of great interest to healthcare executives as well as insurers. Few studies have examined how IT investments influence both efficiency and quality or whether there is an optimal IT investment level that influences both in the desired direction. De…
Antecedents of online banking satisfaction and loyalty: empirical evidence from Finland
2009
This study endeavours to contribute to a better understanding of Service Quality (SQ) in online banking by examining the various dimensions related to creating a satisfactory online banking experience. The authors develop a conceptual model and test it with a convenience sample of 183 online banking users. The empirical test of the model finds strong support for the links between perceived security and Perceived Usefulness (PU) and Perceived Ease Of Use (PEOU), reliability and PU and PEOU, between PEOU and satisfaction and finally between satisfaction and loyalty. The study finally provides both theoretical and practical contributions, outlines the main limitations of the study and gives id…
Trust enhancement of P2PSIP communication systems
2011
Today, peer-to-peer (P2P) session initiation protocol (SIP)-based communication systems have attracted much attention from both academia and industry. The decentralised nature of P2P might provide the distributed P2P communication system without help of the traditional SIP server. However, it comes to the cost of reduced trustworthiness and may cause security problems, e.g., privacy leaks, unpredictable availability, etc. In this paper, we investigate P2PSIP security issues and propose a subjective logic-based trust model that offers trust-based security services during P2PSIP session establishment. The main issues considered in this model include opinion calculation, opinion maintenance, d…
Further Developments and Tests of a Progressive Algorithm for Multiple Criteria Decision Making
1993
P. Korhonen, H. Moskowitz, and J. Wallenius (1986) developed a progressive algorithm and the supporting theory for modeling and solving multiple criteria decision problems with discrete alternatives. A special feature of the algorithm is that it relaxes the usual assumption of a fixed set of available decision alternatives and complete knowledge of a decision maker's (DM's) preference structure or value function. The algorithm is based on progressively sampling the decision space, obtaining preference information from the DM, determining the likelihood of finding possibly/surely better alternatives, and based on this information, continuing the search or terminating it by making the final …
A low-cost multispectral imaging system for the characterisation of soil and small vegetation properties using visible and near-infrared reflectance
2022
Current Proximal Sensing technologies are based on multispectral imaging systems able to capture images in a few spectral bands, usually centred in VIS and NIR regions, to derive vegetation indices. However, most of such systems lack an internal radiometric calibration to estimate the actual reflectance of the observed target, making them sensitive to the local radiative environment and requiring a per-session calibration against a reference target. To overcome such dependence, the instrument described adopts an active illumination of the target surface, allowing the monitoring of soil and low vegetation surfaces by a radiometrically pre-calibrated imaging camera. The system, driven by a mi…
The Chaperone System in Breast Cancer: Roles and Therapeutic Prospects of the Molecular Chaperones Hsp27, Hsp60, Hsp70, and Hsp90
2022
Breast cancer (BC) is a major public health problem, with key pieces of information needed for developing preventive and curative measures still missing. For example, the participation of the chaperone system (CS) in carcinogenesis and anti-cancer responses is poorly understood, although it can be predicted to be a crucial factor in these mechanisms. The chief components of the CS are the molecular chaperones, and here we discuss four of them, Hsp27, Hsp60, Hsp70, and Hsp90, focusing on their pro-carcinogenic roles in BC and potential for developing anti-BC therapies. These chaperones can be targets of negative chaperonotherapy, namely the elimination/blocking/inhibition of the chaperone(s)…
The Chaperone System in Salivary Glands: Hsp90 Prospects for Differential Diagnosis and Treatment of Malignant Tumors
2022
Salivary gland tumors represent a serious medical problem and new tools for differential diagnosis and patient monitoring are needed. Here, we present data and discuss the potential of molecular chaperones as biomarkers and therapeutic targets, focusing on Hsp10 and Hsp90. The salivary glands are key physiological elements but, unfortunately, the information and the means available for the management of their pathologies, including cancer, are scarce. Progress in the study of carcinogenesis has occurred on various fronts lately, one of which has been the identification of the chaperone system (CS) as a physiological system with presence in all cells and tissues (including the salivary gland…
Structural and Dynamic Disturbances Revealed by Molecular Dynamics Simulations Predict the Impact on Function of CCT5 Chaperonin Mutations Associated…
2023
Mutations in genes encoding molecular chaperones, for instance the genes encoding the subunits of the chaperonin CCT (chaperonin containing TCP-1, also known as TRiC), are associated with rare neurodegenerative disorders. Using a classical molecular dynamics approach, we investigated the occurrence of conformational changes and differences in physicochemical properties of the CCT5 mutations His147Arg and Leu224Val associated with a sensory and a motor distal neuropathy, respectively. The apical domain of both variants was substantially but differently affected by the mutations, although these were in other domains. The distribution of hydrogen bonds and electrostatic potentials on the surfa…
An order-adaptive compact approximation Taylor method for systems of conservation laws
2021
Abstract We present a new family of high-order shock-capturing finite difference numerical methods for systems of conservation laws. These methods, called Adaptive Compact Approximation Taylor (ACAT) schemes, use centered ( 2 p + 1 ) -point stencils, where p may take values in { 1 , 2 , … , P } according to a new family of smoothness indicators in the stencils. The methods are based on a combination of a robust first order scheme and the Compact Approximate Taylor (CAT) methods of order 2p-order, p = 1 , 2 , … , P so that they are first order accurate near discontinuities and have order 2p in smooth regions, where ( 2 p + 1 ) is the size of the biggest stencil in which large gradients are n…
Properties of blended mortars produced with recycled by-products from different waste streams
2023
The construction industry encounters significant challenges in effectively managing solid waste produced during the extraction and production of building materials. In different countries, slurry waste generated from granite and marble processing industries, such as glass industry waste, constitutes a considerable portion of the total solid waste. Its undesirable disposal is causing unprecedented environmental damage. Using these non-biodegradable wastes to produce building materials would reduce the environmental burden and contribute to sustainable construction. This study, in detail, investigates the feasibility of utilizing Granite Powder (GP), Ground Granite Powder (GGP), and Ground Gl…