Search results for "Computer Science Applications"
showing 10 items of 3993 documents
A low-cost multispectral imaging system for the characterisation of soil and small vegetation properties using visible and near-infrared reflectance
2022
Current Proximal Sensing technologies are based on multispectral imaging systems able to capture images in a few spectral bands, usually centred in VIS and NIR regions, to derive vegetation indices. However, most of such systems lack an internal radiometric calibration to estimate the actual reflectance of the observed target, making them sensitive to the local radiative environment and requiring a per-session calibration against a reference target. To overcome such dependence, the instrument described adopts an active illumination of the target surface, allowing the monitoring of soil and low vegetation surfaces by a radiometrically pre-calibrated imaging camera. The system, driven by a mi…
The Chaperone System in Breast Cancer: Roles and Therapeutic Prospects of the Molecular Chaperones Hsp27, Hsp60, Hsp70, and Hsp90
2022
Breast cancer (BC) is a major public health problem, with key pieces of information needed for developing preventive and curative measures still missing. For example, the participation of the chaperone system (CS) in carcinogenesis and anti-cancer responses is poorly understood, although it can be predicted to be a crucial factor in these mechanisms. The chief components of the CS are the molecular chaperones, and here we discuss four of them, Hsp27, Hsp60, Hsp70, and Hsp90, focusing on their pro-carcinogenic roles in BC and potential for developing anti-BC therapies. These chaperones can be targets of negative chaperonotherapy, namely the elimination/blocking/inhibition of the chaperone(s)…
The Chaperone System in Salivary Glands: Hsp90 Prospects for Differential Diagnosis and Treatment of Malignant Tumors
2022
Salivary gland tumors represent a serious medical problem and new tools for differential diagnosis and patient monitoring are needed. Here, we present data and discuss the potential of molecular chaperones as biomarkers and therapeutic targets, focusing on Hsp10 and Hsp90. The salivary glands are key physiological elements but, unfortunately, the information and the means available for the management of their pathologies, including cancer, are scarce. Progress in the study of carcinogenesis has occurred on various fronts lately, one of which has been the identification of the chaperone system (CS) as a physiological system with presence in all cells and tissues (including the salivary gland…
Structural and Dynamic Disturbances Revealed by Molecular Dynamics Simulations Predict the Impact on Function of CCT5 Chaperonin Mutations Associated…
2023
Mutations in genes encoding molecular chaperones, for instance the genes encoding the subunits of the chaperonin CCT (chaperonin containing TCP-1, also known as TRiC), are associated with rare neurodegenerative disorders. Using a classical molecular dynamics approach, we investigated the occurrence of conformational changes and differences in physicochemical properties of the CCT5 mutations His147Arg and Leu224Val associated with a sensory and a motor distal neuropathy, respectively. The apical domain of both variants was substantially but differently affected by the mutations, although these were in other domains. The distribution of hydrogen bonds and electrostatic potentials on the surfa…
An order-adaptive compact approximation Taylor method for systems of conservation laws
2021
Abstract We present a new family of high-order shock-capturing finite difference numerical methods for systems of conservation laws. These methods, called Adaptive Compact Approximation Taylor (ACAT) schemes, use centered ( 2 p + 1 ) -point stencils, where p may take values in { 1 , 2 , … , P } according to a new family of smoothness indicators in the stencils. The methods are based on a combination of a robust first order scheme and the Compact Approximate Taylor (CAT) methods of order 2p-order, p = 1 , 2 , … , P so that they are first order accurate near discontinuities and have order 2p in smooth regions, where ( 2 p + 1 ) is the size of the biggest stencil in which large gradients are n…
Properties of blended mortars produced with recycled by-products from different waste streams
2023
The construction industry encounters significant challenges in effectively managing solid waste produced during the extraction and production of building materials. In different countries, slurry waste generated from granite and marble processing industries, such as glass industry waste, constitutes a considerable portion of the total solid waste. Its undesirable disposal is causing unprecedented environmental damage. Using these non-biodegradable wastes to produce building materials would reduce the environmental burden and contribute to sustainable construction. This study, in detail, investigates the feasibility of utilizing Granite Powder (GP), Ground Granite Powder (GGP), and Ground Gl…
Introduction to the Special Issue on Soft Computing Techniques in Materials Science and Engineering
2023
This article has no abstract.
Designing for Mixed Reality Urban Exploration
2021
Funding Information: Acknowledgments. This work was supported by the European Union Seventh Framework Programme (grant agreement no 601139) and the Italian Ministry of Education, University, and Research (MIUR) PON AIM project (id: AIM1875400-1, CUP: B74I18000210006). Publisher Copyright: © 2021. All Rights Reserved. This paper introduces a design framework for mixed reality urban exploration (MRUE), based on a concrete implementation in a historical city. The framework integrates different modalities, such as virtual reality (VR), augmented reality (AR), and haptics-audio interfaces, as well as advanced features such as personalized recommendations, social exploration, and itinerary manage…
Quantum planning for swarm robotics
2023
Computational resources of quantum computing can enhance robotic motion, decision making, and path planning. While the quantum paradigm is being applied to individual robots, its approach to swarms of simple and interacting robots remains largely unexplored. In this paper, we attempt to bridge the gap between swarm robotics and quantum computing, in the framework of a search and rescue mission. We focus on a decision-making and path-planning collective task. Thus, we present a quantum-based path-planning algorithm for a swarm of robots. Quantization enters position and reward information (measured as a robot’s proximity to the target) and path-planning decisions. Pairwise information-exchan…
Correction to: FASTA/Q data compressors for MapReduce-Hadoop genomics: space and time savings made easy
2022
Following publication of the original article [1], the authors identified that the affiliations of Giuseppe Cattaneo and Raffaele Giancarlo were interchanged. The correct affiliations are given below. The correct affiliation of Giuseppe Cattaneo is: 2Dipartimento di Informatica, Università di Salerno, Fisciano, Italy. The correct affiliation of Raffaele Giancarlo is: 3Dipartimento di Matematica ed Informatica, Università di Palermo, Palermo, Italy. The original article [1] has been corrected.