Search results for "Computer simulation"
showing 10 items of 1054 documents
Membrane fluidity and the surface properties of the lipid bilayer: ESR experiment and computer simulation
2009
Penetration of the liposome membranes formed in the gel phase from DPPC (DPPC liposomes) and in the liquid-crystalline phase from egg yolk lecithin (EYL liposomes) by the TEMPO (2,2,6,6-tetramethylpiperidine-1-oxyl) and 16 DOXYL (2-ethyl-2-(15-methoxy-oxopentadecyl)-4,4-dimethyl-3-oxazolidinyloxy) spin probes has been investigated. The penetration process was followed by 120 hours at 24(0)C, using the electron spin resonance (ESR) method. The investigation of the kinetics of the TEMPO probe building into the membranes of both types of liposomes revealed differences appearing 30 minutes after the start of the experiment. The number of TEMPO particles built into the EYL liposome membranes beg…
Analysis and Design of Induction Liquid Metal Processes Using Advanced Numerical Modelling
2019
Comprehensive knowledge of the turbulent flows, heat and mass transfer processes in the melt of induction applications is required to realize efficient metallurgical processes. Therefore, the process oriented development, design and optimization of induction furnaces for melting and casting of metals require praxis oriented simulation and analysis of the complex in-stationary turbulent melt flows and temperature distributions as well as the heat and mass transfer processes in the liquid metal. The studies, presented in this paper, demonstrate the possibilities of using advanced three-dimensional transient numerical modelling for successful simulation of the melt flow as well as heat and mas…
The magnetohydrodynamic force experienced by spherical iron particles in liquid metal
2016
Abstract The paper contains a theoretical investigation of magnetohydrodynamic force experienced by iron particles (well-conducting and ferromagnetic) in well-conducting liquid. The investigation is performed by extending the Leenov and Kolin's theory to take into account the second-order effect. Therefore, the limits of the parent model are taken over to the present results. It is found that the effective conductivity of iron particles in liquid metal, which is important for practical application of the theoretically obtained force, is approximately equal to 1.5·106 S/m. The last result is obtained using a quasi-empirical approach – a comparison of experimental results with the results of …
Particle transport in recirculated liquid metal flows
2008
PurposeAims to present recent activities in numerical modeling of turbulent transport processes in induction crucible furnace.Design/methodology/approach3D large eddy simulation (LES) method was applied for fluid flow modeling in a cylindrical container and transport of 30,000 particles was investigated with Lagrangian approach.FindingsParticle accumulation near the side crucible boundary is determined mainly by the ρp/ρ ratio and according to the presented results. Particle settling velocity is of the same order as characteristic melt flow velocity. Particle concentration homogenization time depends on the internal flow regime. Separate particle tracks introduce very intensive mass exchang…
Validation of a semi-physiological model for caffeine in healthy subjects and cirrhotic patients.
2015
The objective of this paper was to validate a previously developed semi physiological model to simulate bioequivalence trials of drug products. The aim of the model was to ascertain whether the measurement of the metabolite concentration-time profiles would provide any additional information in bioequivalence studies (Fernandez-Teruel et al., 2009a,b; Navarro-Fontestad et al., 2010). The semi-physiological model implemented in NONMEM VI was used to simulate caffeine and its main metabolite plasma levels using caffeine parameters from bibliography. Data from 3 bioequivalence studies in healthy subjects at 3 different doses (100, 175 and 400mg of caffeine) and one study in cirrhotic patients …
Three-dimensional geometrical models of the liver.
2006
In this work we used a virtual approach to study the human liver by three-dimensional geometrical models. We built the models through computer aided geometric modelling techniques starting from pictures taken during both real dissections and diagnostic medical imaging. The results show in a complete modular synthesis and with a schematic iconology the structural organization of this organ in a logic sequence of layers and topographic and spatial relationship among its components. This approach represents an amazing support to clinical anatomy for teaching and research.
A nonlinear observer for rotor flux estimation considering magnetic saturation effects in induction motor drives
2015
This paper proposes a non-linear observer for In- duction Machine (IM) drives which takes into consideration the saturation effects. The non-linear observer is based on an original formulation of the dynamic model of the IM taking into consideration the magnetic saturation of the iron core. A Lyapunov based convergence analysis is proposed in order to suitably compute the observer gain guaranteeing the stability of the observer. The proposed non-linear observer has been tested in numerical simulation and experimentally on a suitably developed test set-up. Its behaviour has been compared to that obtained with a classic Full-Order Luenberger Observer (FOLO) in variable flux working conditions…
Adaptive Neural Stabilizing Controller for a Class of Mismatched Uncertain Nonlinear Systems by State and Output Feedback
2015
In this paper, first, an adaptive neural network (NN) state-feedback controller for a class of nonlinear systems with mismatched uncertainties is proposed. By using a radial basis function NN (RBFNN), a bound of unknown nonlinear functions is approximated so that no information about the upper bound of mismatched uncertainties is required. Then, an observer-based adaptive controller based on RBFNN is designed to stabilize uncertain nonlinear systems with immeasurable states. The state-feedback and observer-based controllers are based on Lyapunov and strictly positive real-Lyapunov stability theory, respectively, and it is shown that the asymptotic convergence of the closed-loop system to ze…
Chaos synchronization for a class of chaotic systems via H<inf>&#x221E;</inf> control technique
2013
In this paper, the robust synchronization control for a class of chaotic systems is studied. Based on linear matrix inequality techniques and Lyapunov stability theory, a novel H∝ robust synchronization controller is designed for the possible application in real engineering. Finally, some numerical simulations are included to demonstrate the effectiveness of the proposed techniques.
Impulsive control on the synchronization for a class of chaotic Systems
2014
In this paper, the impulsive control problem on the synchronization for a class of chaotic systems is discussed. Based on Lyapunov stability theory, the new impulsive synchronization strategy is presented to realize the chaos synchronization and possesses the wider scope of application. Finally the numerical simulation examples are given to demonstrate the effectiveness of our theoretical results.