Search results for "Computer-Assisted"

showing 10 items of 1186 documents

Low light level in vitro monitoring of cellular and antigen-antibody reactions using a photon detection camera system — New perspectives for clinical…

1990

This article briefly describes the use of a photon counting system (ARGUS-100) in the detection of low levels of light. The ARGUS-100 was used in determining ATP in cell sections from tumor tissues and in measuring a luminescence-enhanced immunoluminometric assay, using ferritin as the analyte, based on the luminol-peroxide-4-iodophenol reaction with peroxidase as the enzyme. The aim is not so much the presentation of data, but rather to show the potentials of the photon counting camera in increasing our knowledge of the cellular and subcellular levels, as well as lowering the detection limits in already sensitive systems, such as immunoassays.

Blood GlucoseAnalyteVideo RecordingNanotechnologyAdenocarcinomaCell Linelaw.inventionAntigen-Antibody ReactionsImmunoenzyme TechniquesAdenosine TriphosphateMicrocomputersComputer SystemslawRhabdomyosarcomaDrug DiscoveryTumor Cells CulturedAnimalsHumansBioluminescenceLactic AcidGenetics (clinical)ChemiluminescenceDetection limitChemistrySignal Processing Computer-AssistedGeneral MedicineIn vitroPhoton countingRatsLow light levelClinical diagnosisLuminescent MeasurementsLactatesBiophysicsMolecular MedicineKlinische Wochenschrift
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The influence of different generations of computer algorithms on diabetes control

1990

With all control schedules, the management of diabetes is possible using Skyler's algorithm. In general, those control algorithms which do not allow the individual adaptation to changing conditions lead to overinsulinisation. So-called meal-related algorithms do usually minimise the fluctuations in blood sugar. The introduction of self-adapting algorithms, detecting peripheral insulin resistance, may further improve metabolic diabetes control.

Blood GlucoseControl algorithmbusiness.industryControl (management)Blood sugarHealth InformaticsPeripheral insulin resistancemedicine.diseaseDrug Administration ScheduleComputer Science ApplicationsEatingDiabetes controlTherapy Computer-AssistedDiabetes mellitusDiabetes MellitusmedicineHumansInsulinProspective StudiesAdaptation (computer science)businessAlgorithmAlgorithmsSoftwareRetrospective StudiesComputer Methods and Programs in Biomedicine
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Extensive Assessment of Blood Glucose Monitoring During Postprandial Period and Its Impact on Closed-Loop Performance.

2017

[EN] Background: Closed-loop (CL) systems aims to outperform usual treatments in blood glucose control and continuous glucose monitors (CGM) are a key component in such systems. Meals represents one of the main disturbances in blood glucose control, and postprandial period (PP) is a challenging situation for both CL system and CGM accuracy. Methods: We performed an extensive analysis of sensor¿s performance by numerical accuracy and precision during PP, as well as its influence in blood glucose control under CL therapy. Results: During PP the mean absolute relative difference (MARD) for both sensors presented lower accuracy in the hypoglycemic range (19.4 ± 12.8%) than in other ranges (12.2…

Blood GlucoseMaleTime FactorsGlucose controlEndocrinology Diabetes and MetabolismSpecial Section: Artificial Pancreas: Models Signals and Control0302 clinical medicineInsulin030212 general & internal medicineContinuous glucose monitoringAccuracymedicine.diagnostic_testContinuous glucose monitoringPostprandial periodSignal Processing Computer-AssistedMiddle AgedPostprandial PeriodINGENIERIA DE SISTEMAS Y AUTOMATICAType 1 diabetesPostprandialTreatment OutcomeClosed-loop controlCardiologyFemaleGlucose monitorsAlgorithmsAdultmedicine.medical_specialtyTransducersBiomedical Engineering030209 endocrinology & metabolismBioengineering03 medical and health sciencesInsulin Infusion SystemsPredictive Value of TestsInternal medicineInternal MedicinemedicineHumansHypoglycemic AgentsBlood glucose monitoringType 1 diabetesbusiness.industryBlood Glucose Self-MonitoringReproducibility of Resultsmedicine.diseaseHypoglycemiaEndocrinologyDiabetes Mellitus Type 1businessClosed loopBiomarkersJournal of diabetes science and technology
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Towards understanding the complexity of cardiovascular oscillations: Insights from information theory.

2018

Abstract Cardiovascular complexity is a feature of healthy physiological regulation, which stems from the simultaneous activity of several cardiovascular reflexes and other non-reflex physiological mechanisms. It is manifested in the rich dynamics characterizing the spontaneous heart rate and blood pressure variability (HRV and BPV). The present study faces the challenge of disclosing the origin of short-term HRV and BPV from the statistical perspective offered by information theory. To dissect the physiological mechanisms giving rise to cardiovascular complexity in different conditions, measures of predictive information, information storage, information transfer and information modificati…

Blood pressure variabilityAdultMalemedicine.medical_specialtySupine positionAdolescent0206 medical engineeringInformation TheoryHealth InformaticsBlood Pressure02 engineering and technologyBaroreflexCardiovascular Physiological Phenomena03 medical and health sciencesElectrocardiographyYoung AdultRedundancy0302 clinical medicineHeart RateInternal medicineHeart ratemedicineHeart rate variabilityHumansVagal toneHeart rate variabilitybusiness.industryModels CardiovascularCardiorespiratory fitnessSignal Processing Computer-AssistedComplexity020601 biomedical engineeringComputer Science ApplicationsCausalityBlood pressureSettore ING-INF/06 - Bioingegneria Elettronica E InformaticaCardiologyFemalebusiness030217 neurology & neurosurgeryRespiratory minute volumeComputers in biology and medicine
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Developmental differences in the uterus of Fasciola hepatica between livestock liver fluke populations from Bolivian highlands and European lowlands

2001

A morphometric study of the uterus area (UA) of Fasciola hepatica adults was carried out with the aid of a computer linked to a stereomicroscopic 3CCD colour video camera using image analysis software. The UA of adult liver flukes found in naturally infected sheep, cattle and pig from the endemic human fascioliasis zone of the northern Bolivian Altiplano highlands was compared with that of flukes found infecting sheep and cattle from Valencia, Spain and cattle from Corsica, France (collectively, European lowlands). Liver fluke UA was examined using an allometric model. A comparison of the allometry of the liver fluke UA in different host species from Bolivia revealed no significant differen…

BoliviaFascioliasisSwinePopulationHelminthiasisCattle DiseasesSheep DiseasesZoologyHost-Parasite Interactionsparasitic diseasesImage Processing Computer-AssistedmedicineAnimalsFasciola hepaticaParasite hostingeducationSwine Diseaseseducation.field_of_studySheepGeneral VeterinarybiologyHost (biology)Ecologybusiness.industryAltitudeUterusGeneral MedicineFasciola hepaticaLiver flukebiology.organism_classificationmedicine.diseaseEuropeInfectious DiseasesAnimals DomesticInsect ScienceCattleFemaleParasitologyLivestockTrematodabusinessParasitology Research
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A COLLABORATIVE VIRTUAL REALITY ENVIRONMENT FOR NEUROSURGICAL PLANNING AND TRAINING

2007

OBJECTIVE We have developed a highly interactive virtual environment that enables collaborative examination of stereoscopic three-dimensional (3-D) medical imaging data for planning, discussing, or teaching neurosurgical approaches and strategies. MATERIALS AND METHODS The system consists of an interactive console with which the user manipulates 3-D data using hand-held and tracked devices within a 3-D virtual workspace and a stereoscopic projection system. The projection system displays the 3-D data on a large screen while the user is working with it. This setup allows users to interact intuitively with complex 3-D data while sharing this information with a larger audience. RESULTS We have…

Brain Diseasesbusiness.industryEducational TechnologyNeurosurgeryComputer-Assisted InstructionStereoscopyPlan (drawing)Virtual realitycomputer.software_genrelaw.inventionImaging Three-DimensionallawHuman–computer interactionVirtual machineMedical imagingHumansMedicineComputer SimulationSurgeryNeurology (clinical)businessProjection (set theory)computerComputer-Assisted InstructionInstructional simulationOperative Neurosurgery
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Influence of the scalp thickness on the intracranial contribution to rheoencephalography

2004

In spite of the great efforts made by the scientific community, up to now there is no agreement about the rheoencephalography (REG) capability to reflect cerebral blood flow (CBF). Moreover, a standard procedure and the optimal electrode arrangement have not been established yet. In a previous study, we found, using a classical four-shell spherical model of the head and solving it by numerical methods that, theoretically, there could exist an electrode arrangement to register an REG II free of extracranial contribution. In this paper, we have studied the influence of scalp thickness on the intracranial contribution to REG II. The study has been performed by solving the head model, using in …

Brain MappingScalpRadiological and Ultrasound TechnologyModels NeurologicalMathematical analysisModels CardiovascularBrainElectroencephalographyStandard procedureRheoencephalographymedicine.anatomical_structureCerebral blood flowCerebrovascular CirculationScalpHead modelmedicineHumansComputer SimulationRadiology Nuclear Medicine and imagingDiagnosis Computer-AssistedPlethysmography ImpedanceAlgorithmMathematicsPhysics in Medicine and Biology
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Interdisciplinary consensus on the uses and technique of MR-guided vacuum-assisted breast biopsy (VAB): results of a European consensus meeting.

2009

Abstract Purpose Quality assurance of MR-guided vacuum-assisted breast biopsy (VAB). Method A consensus was achieved based on the existing literature and experience of an interdisciplinary group comprising European specialists in breast imaging and VAB. Results Full imaging work-up must be completed according to existing standards before an indication for MR-guided VAB is established. The procedure should be reserved for lesions demonstrable by MRI alone. Acquisition of >24 cores (11-Gauge) should be routinely attempted, with the intention of sufficiently removing small lesions for accurate diagnosis. Following biopsy the patient should be re-imaged to demonstrate the biopsy site and its pr…

Breast biopsymedicine.medical_specialtymedicine.diagnostic_testBreast imagingbusiness.industryBiopsy NeedleMEDLINEGeneral MedicineAuditMagnetic Resonance ImagingSurgeryEuropeBiopsy SiteSurgery Computer-AssistedBiopsyVacuum-assisted breast biopsyPractice Guidelines as TopicmedicineHumansRadiology Nuclear Medicine and imagingMedical physicsSampling (medicine)businessEuropean journal of radiology
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A Ciliary Motility Index for Activity Measurement in Cell Cultures With Respiratory Syncytial Virus

2018

[EN] Background: The respiratory epithelium is frequently infected by the respiratory syncytial virus, resulting in inflammation, a reduction in cilia activity and an increase in the production of mucus. Methods: In this study, an automatic method has been proposed to characterize the ciliary motility from cell cultures by means of a motility index using a dense optical flow algorithm. This method allows us to determine the ciliary beat frequency (CBF) together with a ciliary motility index of the cells in the cultures. The object of this analysis is to automatically distinguish between normal and infected cells in a culture. Results: The method was applied in 2 stages. It was concluded fro…

BronchiInflammationRespiratory syncytial virusVirusMicrobiologyTECNOLOGIA ELECTRONICA03 medical and health sciences0302 clinical medicineCell MovementMotility indexImage Processing Computer-AssistedHumansCiliary motility: Cell culturesImmunology and AllergyMedicineCiliaRespiratory system030223 otorhinolaryngologyCells Culturedbusiness.industryCell cultures [Ciliary motility]CiliumOptical ImagingCiliary beat frequencyEpithelial CellsGeneral MedicineCiliary motilityhumanitiesRespiratory Syncytial VirusesActivity measurements030228 respiratory systemOtorhinolaryngologyCell cultureFISICA APLICADARespiratory epitheliumRespiratory epitheliumCiliary beat patternmedicine.symptomDense optical flowbusinessMATEMATICA APLICADAAlgorithms
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3D segmentation of abdominal aorta from CT-scan and MR images

2012

International audience; We designed a generic method for segmenting the aneurismal sac of an abdominal aortic aneurysm (AAA) both from multi-slice MR and CT-scan examinations. It is a semi-automatic method requiring little human intervention and based on graph cut theory to segment the lumen interface and the aortic wall of AAAs. Our segmentation method works independently on MRI and CT-scan volumes and has been tested on a 44 patient dataset and 10 synthetic images. Segmentation and maximum diameter estimation were compared to manual tracing from 4 experts. An inter-observer study was performed in order to measure the variability range of a human observer. Based on three metrics (the maxim…

CT scanmedicine.medical_specialty[INFO.INFO-IM] Computer Science [cs]/Medical ImagingLumen (anatomy)Health Informatics02 engineering and technologyAAA segmentationPattern Recognition Automated030218 nuclear medicine & medical imaging03 medical and health sciencesAortic aneurysmImaging Three-Dimensional0302 clinical medicineCutmedicine.arteryImage Interpretation Computer-Assisted[INFO.INFO-IM]Computer Science [cs]/Medical Imaging0202 electrical engineering electronic engineering information engineeringmedicineHumansRadiology Nuclear Medicine and imagingSegmentationMathematicsAnalysis of VarianceRadiological and Ultrasound Technology[ INFO.INFO-IM ] Computer Science [cs]/Medical ImagingVolume segmentationAbdominal aortaReproducibility of Resultsmedicine.diseaseComputer Graphics and Computer-Aided DesignAbdominal aortic aneurysmHausdorff distancecardiovascular system020201 artificial intelligence & image processingComputer Vision and Pattern RecognitionTomographyRadiologyTomography X-Ray ComputedAlgorithmsMagnetic Resonance AngiographyGraph cutAortic Aneurysm AbdominalMRI
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