Search results for "Computer-aided"

showing 10 items of 416 documents

Liquid crystal spatial light modulator with very large phase modulation operating in high harmonic orders.

2013

Unusually large phase modulation in a commercial liquid crystal spatial light modulator (LCSLM) is reported. Such a situation is obtained by illuminating with visible light a device designed to operate in the infrared range. The phase modulation range reaches 6π radians in the red region of the visible spectrum and 10π radians in the blue region. Excellent diffraction efficiency in high harmonic orders is demonstrated despite a concomitant and non-negligible Fabry–Perot interference effect. This type of SLM opens the possibility to implement diffractive elements with reduced chromatic dispersion or chromatic control.

DiffractionMaterials scienceLightInfraredbusiness.industryColorEquipment DesignDiffraction efficiencyAtomic and Molecular Physics and OpticsLiquid CrystalsEquipment Failure AnalysisRefractometryOpticsOptical modulatorInterferometryDispersion (optics)Materials TestingOptoelectronicsComputer-Aided DesignScattering RadiationChromatic scalebusinessPhase modulationLightingVisible spectrumOptics letters
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On the Existence of 1-Bounded Bi-ideals with the WELLDOC Property

2015

A combinatorial condition called well distributedoccurrences, or WELLDOC for short, has been introducedrecently. The proofs that WELLDOC property holds for thefamily of Sturmian words, and more generally, for Arnoux-Rauzy words are given in two papers by Balkova et al. The WELLDOC property for bounded bi-ideals is analysed inthis paper. The existence of a 1-bounded bi-ideal over thefinite alphabet that satisfies the WELLDOC property has beenproved by the authors.

Discrete mathematicsAlgebraProperty (philosophy)Computer scienceBounded functionAlphabetComputer-aided software engineeringMathematical proofElectronic mail2015 17th International Symposium on Symbolic and Numeric Algorithms for Scientific Computing (SYNASC)
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Nondeterministic Unitary OBDDs

2017

We investigate the width complexity of nondeterministic unitary OBDDs (NUOBDDs). Firstly, we present a generic lower bound on their widths based on the size of strong 1-fooling sets. Then, we present classically “cheap” functions that are “expensive” for NUOBDDs and vice versa by improving the previous gap. We also present a function for which neither classical nor unitary nondeterminism does help. Moreover, based on our results, we present a width hierarchy for NUOBDDs. Lastly, we provide the bounds on the widths of NUOBDDs for the basic Boolean operations negation, union, and intersection.

Discrete mathematicsHierarchy (mathematics)Intersection (set theory)010102 general mathematics0102 computer and information sciencesFunction (mathematics)Computer Science::Computational Complexity01 natural sciencesUpper and lower boundsUnitary stateNondeterministic algorithmCombinatoricsNegation010201 computation theory & mathematicsBoolean operations in computer-aided design0101 mathematicsMathematics
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Programming languages for data-Intensive HPC applications: A systematic mapping study

2020

This work is a result of activities from COST Action 10406 High -Performance Modelling and Simulation for Big Data Applications (cHiPSet), funded by the European Cooperation in Science and Technology. FCT, Portugal for grants: NOVA LINCS Research Laboratory Ref. UID/ CEC/ 04516/ 2019); INESC-ID Ref. UID/CEC/50021/2019; BioISI Ref. UID/MULTI/04046/2103; LASIGE Research Unit Ref. UID/CEC/00408/ 2019. A major challenge in modelling and simulation is the need to combine expertise in both software technologies and a given scientific domain. When High-Performance Computing (HPC) is required to solve a scientific problem, software development becomes a problematic issue. Considering the complexity…

Domain-Specific language (DSL)High performance computing (HPC)Computer scienceComputer Networks and CommunicationsBig data; Data-intensive applications; Domain-Specific language (DSL); General-Purpose language (GPL); High performance computing (HPC); Programming languages; Systematic mapping study (SMS)Systematic mapping study (SMS)Big dataData-intensive applicationsContext (language use)computer.software_genreTheoretical Computer ScienceSoftware portabilityBig dataSoftwareArtificial Intelligencebusiness.industryProgramming languageSoftware developmentGeneral-Purpose language (GPL)UsabilityProgramming languagesDigital libraryComputer Graphics and Computer-Aided DesignHardware and ArchitecturebusinesscomputerSoftware
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New antitrichomonal drug-like chemicals selected by bond (edge)-based TOMOCOMD-CARDD descriptors.

2008

Bond-based quadratic indices, new TOMOCOMD-CARDD molecular descriptors, and linear discriminant analysis (LDA) were used to discover novel lead trichomonacidals. The obtained LDA-based quantitative structure-activity relationships (QSAR) models, using nonstochastic and stochastic indices, were able to classify correctly 87.91% (87.50%) and 89.01% (84.38%) of the chemicals in training (test) sets, respectively. They showed large Matthews correlation coefficients of 0.75 (0.71) and 0.78 (0.65) for the training (test) sets, correspondingly. Later, both models were applied to the virtual screening of 21 chemicals to find new lead antitrichomonal agents. Predictions agreed with experimental resu…

DrugAdultQuantitative structure–activity relationshipStereochemistrymedia_common.quotation_subjectOvariectomyDrug Evaluation PreclinicalTrichomonas InfectionsAntitrichomonal AgentsBiochemistryAnalytical Chemistrychemistry.chemical_compoundIn vivoMolecular descriptorDrug Resistance BacterialTrichomonas vaginalisAnimalsHumansRats Wistarmedia_commonChromatographyMolecular StructureChemistryDiscriminant AnalysisLinear discriminant analysisRatsAntitrichomonal agentEdge basedMolecular MedicineComputer-Aided DesignFemaleSoftwareBiotechnologyJournal of biomolecular screening
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Diseño gráfico para formar al profesorado de primaria

2021

Educar en diseño es probablemente la base para una predisposición social hacia la creatividad y la innovación. Presentamos los resultados de una investigación desarrollada en la práctica universitaria, formulada metodológicamente como estudio de caso. Incorporamos la práctica del diseño gráfico al currículum formativo de Maestro/a en Educación Primaria. Si queremos que la ciudadanía aprecie el diseño, conviene preparar al profesorado. Para lograr este acercamiento al diseño gráfico planteamos un taller en el que cada participante elabora su propio exlibris. Los resultados positivos nos animan a continuar con este tipo de iniciativas que aglutinan diseño, patrimonio, identidad e inclusión. E…

Educación artísticaNC1-1940Visual Arts and Performing Artsmedia_common.quotation_subjectIdentity (social science)diseño gráficoDrawing. Design. Illustrationformación del profesoradoDissenyIdentityPedagogyResearch basedSociologyidentidadCurriculummedia_commonInclusionFormación del profesoradobusiness.industryCommunicationGraphic designGraphic designCreativityComputer Graphics and Computer-Aided DesigninclusiónIdentidadDiseño gráficoTeacher trainingArt educationInclusiónbusinessInclusion (education)educación artísticagrafica
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Human exome and mouse embryonic expression data implicate ZFHX3, TRPS1, and CHD7 in human esophageal atresia

2020

Introduction Esophageal atresia with or without tracheoesophageal fistula (EA/TEF) occurs approximately 1 in 3.500 live births representing the most common malformation of the upper digestive tract. Only half a century ago, EA/TEF was fatal among affected newborns suggesting that the steady birth prevalence might in parts be due to mutational de novo events in genes involved in foregut development. Methods To identify mutational de novo events in EA/TEF patients, we surveyed the exome of 30 case-parent trios. Identified and confirmed de novo variants were prioritized using in silico prediction tools. To investigate the embryonic role of genes harboring prioritized de novo variants we perfor…

EmbryologyCandidate geneGene ExpressionTranscriptomeMiceDatabase and Informatics MethodsMedicine and Health SciencesExomeExomeExome sequencingGenetics0303 health sciencesMultidisciplinaryComputer-Aided Drug DesignQ030305 genetics & hereditySequence analysisRGenomicsCongenital AnomaliesDNA-Binding Proteinsembryonic structuresAmino Acid AnalysisMedicineTranscriptome AnalysisTracheoesophageal FistulaResearch ArticleDrug Research and DevelopmentBioinformaticsSequence analysisScienceIn silicoBiologyResearch and Analysis Methods03 medical and health sciencesExome SequencingGeneticsCongenital DisordersAnimalsHumansddc:610Molecular Biology TechniquesEsophageal AtresiaMolecular BiologyDNA sequence analysis030304 developmental biologyHomeodomain ProteinsPharmacologyMolecular Biology Assays and Analysis TechniquesGene Expression ProfilingEmbryosDNA HelicasesBiology and Life SciencesComputational BiologyEmbryo MammalianGenome AnalysisFANCBRepressor ProteinsGene expression profilingBiological DatabasesDrug DesignMutation DatabasesMutationDevelopmental Biology
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Study on the application of CAM techniques on CNC lathes with Y axis and driven tools

2021

Abstract CNC lathes with Y axes and driven tools are machine-tools with complex kinematic. Using CAM techniques to program these machines is a cumbersome process and could easily lead to collisions. Collisions may occur not only between tools and workpiece but also between the mobile elements of the CNC lathe. While CAM software package can identify the first type of collisions, for the second type supplementary measures must be taken. This work presents the build of a kinematic model of such a CNC lathe and how can the CAM techniques be improved by using this model.

Engineering drawingComputer scienceComputer-aided manufacturingProcess (computing)ComputerApplications_COMPUTERSINOTHERSYSTEMSKinematicsIOP Conference Series: Materials Science and Engineering
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Dental anatomy portrayed with microscopic volume investigations

1993

The clinical treatment of the root canal of teeth--called endodontics--assumes a precise idea of the spatial arrangement of the anatomy of teeth and their inner structure. By using computer-assisted data acquisition from filmed sequences of histologic serial sections and a special kind of magnetic resonance microscope--the Stray Field Imaging (STRAFI)--volume investigations were carried out using special functions of a newly developed 3D software. Possible applications and future perspectives are discussed.

Engineering drawingDental anatomyComputer scienceHealth InformaticsTooth rootImage Processing Computer-AssistedHumansRadiology Nuclear Medicine and imagingTooth RootClinical treatmentDental PulpMicroscopyData displayRadiological and Ultrasound Technologybusiness.industryVolume renderingImage enhancementImage EnhancementMagnetic Resonance ImagingMolarComputer Graphics and Computer-Aided DesignData DisplayComputer Vision and Pattern RecognitionDental Pulp CavityNuclear medicinebusinessToothSoftwareVolume (compression)Computerized Medical Imaging and Graphics
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SOFTWARE FOR DRILLING TOOL DESIGN AND MANUFACTURING

2007

Abstract The paper presents a software that allows the design and manufacturing of cutting tools for boring. The methodology contains several steps that can be taken only by using the software modules. The main stages are the geometrical and dimensional design of the cutting tool, the design and generation of the abrasive profiled disks, the management of abrasive disks and disk package, the generation of the manufacturing technology, the verification of the cutting tool using virtual simulation, testing the manufacturing process using virtual simulation, generating the CNC files and finally the transmission of the CNC files in real time to the CNC machine tool so that the tools can be manu…

Engineering drawingEngineeringCutting toolbusiness.industryAbrasiveDrillingComputerApplications_COMPUTERSINOTHERSYSTEMSGeneral Medicinecomputer.software_genreManufacturing engineeringSoftwareComputer-integrated manufacturingComputer-aided manufacturingNumerical controlComputer Aided DesignbusinesscomputerIFAC Proceedings Volumes
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