Search results for "Concentration"

showing 10 items of 1906 documents

<title>Refractive properties of separate erythrocytes of Chernobyl clean-up workers at different pH</title>

2000

This study is focused on the modifications in erythrocytes of Chernobyl nuclear power plant accident clean-up workers as a late health effect of short-term impact of high level radioactive contamination. As a result, a new method based on erythrocyte (RBC) refractive index properties at different pH has been elaborated. According to the light dispersion theory for fluids refractive index is associated with molecules mass m. This feature is widely used for estimation of cell dry mass. But there is another refractive index dependency from molecules charge q regardless of its sing. This feature is not being used for cell quantitative and qualitative characterization. In this study, RBC were in…

education.field_of_studyIsoelectric pointChemistryRadioactive contaminationLight dispersionDispersion (optics)PopulationAnalytical chemistryMineralogyMean cell hemoglobin concentrationOccupational exposureeducationRefractive indexSPIE Proceedings
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Eating patterns are associated with biomarkers in a selected population of university students and employees.

2011

AbstractThe association between diet and CVD cannot be assigned to a single nutrient, but rather to a set of nutrients and non-nutrients, and eating pattern analyses have become an important tool in investigation of this relationship. Our objective was to investigate eating patterns in relation to nutrient intake and serum concentration of folate, vitamin B12 and TAG in ninety-five healthy adult participants. Dietary information was collected by an FFQ, and eating patterns were obtained by principal components analyses of thirty-three food groups. Three eating patterns were extracted, a sweet eating pattern identified by intakes of cakes, snacks, sugar-sweetened drinks and chocolates; a pru…

education.field_of_studyNutrition and Dieteticsbusiness.industryEndocrinology Diabetes and MetabolismSerum folatePopulationdigestive oral and skin physiologyDietary Surveys and Nutritional EpidemiologyNegative associationSerum concentrationEating patternsCVDFood groupEnvironmental healthTAGRed meatMedicineVitamin B12Food sciencebusinesseducationBiomarkersFood ScienceMorningOlive oilJournal of nutritional science
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Some aspects related to stability, critical concentrations and kinetics of flocculation of the calcium phytate colloid

1986

Abstract As 99mTcCa phytate is an important radiopharmaceutical and its colloidal nature presents problems, we investigated some of them. This work describes the study of the colloidal behaviour of the calcium phytate colloid in terms of its formation, stability and kinetics of flocculation. The study of spontaneous, and centrifugation-induced flocculation allows the determination of two critical concentrations of sol flocculation. The titrations of calcium phytate colloid at different concentrations provide information on the colloidal formation conditions. Moreover, a study on flocculation kinetics was made by turbidity measurements.

endocrine systemFlocculationAqueous solutionChemistrydigestive oral and skin physiologyKineticsGeneral EngineeringConcentration effectcomplex mixturesbody regionsColloidChemical engineeringBiochemistryCalcium CompoundsTitrationTurbidityInternational Journal of Radiation Applications and Instrumentation. Part A. Applied Radiation and Isotopes
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Context dependent variation in corticosterone and phenotypic divergence of Rana arvalis populations along an acidification gradient

2022

Background Physiological processes, as immediate responses to the environment, are important mechanisms of phenotypic plasticity and can influence evolution at ecological time scales. In stressful environments, physiological stress responses of individuals are initiated and integrated via the release of hormones, such as corticosterone (CORT). In vertebrates, CORT influences energy metabolism and resource allocation to multiple fitness traits (e.g. growth and morphology) and can be an important mediator of rapid adaptation to environmental stress, such as acidification. The moor frog, Rana arvalis, shows adaptive divergence in larval life-histories and predator defense traits along an acidi…

endocrine systemviitasammakkoRanidaeEvolutionAcidification; Adaptive divergence; Amphibians; Corticosterone; Environmental stress; Evolutionary physiology; Phenotypic plasticityEnvironmental stressPhenotypic plasticitykortikosteroniEvolutionsbiologiAcidificationAmphibiansAdaptive divergencehappamoituminenQH359-425polycyclic compoundsAnimalsHumanshormonaaliset vaikutuksetQH540-549.5sopeutuminenEkologiEvolutionary BiologyEcologysammakkoeläimetHydrogen-Ion ConcentrationAdaptation PhysiologicalLarvaEvolutionary physiologyfenotyyppiAnuraCorticosteroneAcidsympäristönmuutoksethormones hormone substitutes and hormone antagonistsfysiologiset vaikutuksetResearch ArticleBMC Ecology and Evolution
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Reconfigurable DNA Origami Nanocapsule for pH-Controlled Encapsulation and Display of Cargo

2019

DNA nanotechnology provides a toolbox for creating custom and precise nanostructures with nanometer-level accuracy. These nano-objects are often static by nature and serve as versatile templates for assembling various molecular components in a user-defined way. In addition to the static structures, the intrinsic programmability of DNA nanostructures allows the design of dynamic devices that can perform predefined tasks when triggered with external stimuli, such as drug delivery vehicles whose cargo display or release can be triggered with a specified physical or chemical cue in the biological environment. Here, we present a DNA origami nanocapsule that can be loaded with cargo and reversibl…

entsyymitMaterials scienceta221enzymesMetal NanoparticlesGeneral Physics and AstronomyNanoparticleNanotechnology02 engineering and technology010402 general chemistry01 natural sciencesArticleBiophysical PhenomenaNanocapsulesDrug Delivery SystemsNanocapsulesDNA nanotechnologyFluorescence Resonance Energy TransferDNA origamiDNA nanotechnologyGeneral Materials ScienceA-DNApH controlGeneral EngineeringnanobiotekniikkaDNAHydrogen-Ion Concentration021001 nanoscience & nanotechnologyNanostructures0104 chemical sciencesFörster resonance energy transferTemplateFörster resonance energy transferdrug deliveryDrug deliveryNucleic Acid ConformationnanohiukkasetnanoparticlesGoldDNA origami0210 nano-technologyACS Nano
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Control of Growth and Persistence of Listeria monocytogenes and β-Lactam-Resistant Escherichia coli by Thymol in Food Processing Settings

2020

The main objective of this study was to evaluate the efficacy of thymol in controlling environmental contamination in food processing facilities. The effect of thymol was tested as an agent to prevent planktonic and bacterial biofilm growth of twenty-five Listeria monocytogenes isolates from a variety of foods and five Escherichia coli isolates from a farm. The E. coli isolates were positive for extended spectrum &beta

esblSettore CHIM/10 - Chimica Degli Alimenti<i>escherichia coli</i>Pharmaceutical ScienceSettore BIO/19 - Microbiologia Generalemedicine.disease_causebiofilmAnalytical ChemistryPersistence (computer science)lcsh:QD241-44103 medical and health scienceschemistry.chemical_compoundMinimum inhibitory concentrationlcsh:Organic chemistryListeria monocytogenesthymolDrug DiscoveryEscherichia colimedicineFood sciencePhysical and Theoretical ChemistryEscherichia coliThymolListeria monocytogene030304 developmental biology0303 health sciences030306 microbiologyOrganic ChemistryBiofilmContaminationchemistryChemistry (miscellaneous)<i>listeria monocytogenes</i>LactamMolecular MedicineMolecules
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Synthesis and Antiproliferative Activity of 2,5-bis(3′-Indolyl)pyrroles, Analogues of the Marine Alkaloid Nortopsentin

2013

2,5-bis(3′-Indolyl)pyrroles, analogues of the marine alkaloid nortopsentin, were conveniently prepared through a three step procedure in good overall yields. Derivatives 1a and 1b exhibited concentration-dependent antitumor activity towards a panel of 42 human tumor cell lines with mean IC50 values of 1.54 μM and 0.67 μM, respectively. Investigating human tumor xenografts in an ex-vivo clonogenic assay revealed selective antitumor activity, whereas sensitive tumor models were scattered among various tumor histotypes.

ex-vivo xenograftsIndolesStereochemistryPharmaceutical ScienceMice NudeAntineoplastic AgentsArticleInhibitory Concentration 50MiceCell Line TumorNeoplasmsDrug Discoverybis-indolyl-pyrroles; nortopsentin analogues; marine alkaloids; antitumor; <i>ex-vivo </i>xenograftsIc50 valuesAnimalsHumansnortopsentin analoguePyrrolesClonogenic assayPharmacology Toxicology and Pharmaceutics (miscellaneous)lcsh:QH301-705.5Tumor Stem Cell AssayMice nudeantitumorAntitumor activityDose-Response Relationship DrugChemistryAlkaloidbis-indolyl-pyrroles; nortopsentin analogues; marine alkaloids; antitumor; ex-vivo xenograftsImidazolesTumor Stem Cell AssaySettore CHIM/08 - Chimica FarmaceuticaXenograft Model Antitumor Assaysbis-indolyl-pyrrolemarine alkaloidHuman tumornortopsentin analogueslcsh:Biology (General)Cell culturebis-indolyl-pyrrolesmarine alkaloidsMarine Drugs
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Glial Chloride Homeostasis Under Transient Ischemic Stress

2021

High water permeabilities permit rapid adjustments of glial volume upon changes in external and internal osmolarity, and pathologically altered intracellular chloride concentrations ([Cl–]int) and glial cell swelling are often assumed to represent early events in ischemia, infections, or traumatic brain injury. Experimental data for glial [Cl–]int are lacking for most brain regions, under normal as well as under pathological conditions. We measured [Cl–]int in hippocampal and neocortical astrocytes and in hippocampal radial glia-like (RGL) cells in acute murine brain slices using fluorescence lifetime imaging microscopy with the chloride-sensitive dye MQAE at room temperature. We observed s…

excitatory amino acid transportersOsmotic concentrationchemical stress mimicking ischemiaChemistryDentate gyrusINTintracellular chloride concentrationsNeurosciences. Biological psychiatry. NeuropsychiatryHippocampal formationChlorideCellular and Molecular NeuroscienceNa-K-2Cl cotransporterBiophysicsmedicineddc:610K-Cl cotransportersCotransporterHomeostasisIntracellularRC321-571NeuroscienceOriginal Researchfluorescence lifetime imaging microscopymedicine.drugFrontiers in Cellular Neuroscience
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Sulfate sensitivity of aquatic organism in soft freshwaters explored by toxicity tests and species sensitivity distribution

2023

Elevated concentrations of sulfate in waterways are observed due to various anthropogenic activities. Elevated levels of sulfate can have harmful effects on aquatic life in freshwaters: sulfate can cause osmotic stress or specific ion toxicity in aquatic organisms, especially in soft waters where Ca2+ and Mg2+ concentrations are low. Formerly, chronic toxicity test data in soft water have been scarce. The chronic and acute sulfate toxicity tests conducted with aquatic organisms from 10 families across various trophic levels in this study multiplied the number of tests conducted in soft freshwater conditions and enabled derivation of the species sensitivity distribution (SSD) and sulfate haz…

fishvesieläimistövesistötvesien saastuminenHealth Toxicology and MutagenesisPublic Health Environmental and Occupational Healthaquatic risk assessmentvesiekosysteemitGeneral MedicineriskinarviointiselkärangattomatmyrkyllisyysinvertebratesvedenlaatuPollutionmacrophyteshazardous concentrationsulfaatitpitoisuusphytoplanktonmakea vesikalat
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Effect of oxidoreduction potential and of gas bubbling on rheological properties and microstructure of acid skim milk gels acidified with glucono-del…

2009

Milk oxidoreduction potential was modified using gases during the production of a model dairy product and its effect on gel setting was studied. Acidification by glucono-delta-lactone was used to examine the physicochemistry of gelation and to avoid variations due to microorganisms sensitive to oxidoreduction potential. Four conditions of oxidoreduction potential were applied to milk: milk was gassed with air, nongassed, gassed with N(2), or gassed with N(2)H(2). The rheological properties and microstructure of these gels were determined using viscoelasticimetry, measurement of whey separation, and confocal laser scanning microscopy. It appeared that a reducing environment led to less-aggre…

food.ingredientMicroorganism[ SDV.AEN ] Life Sciences [q-bio]/Food and NutritionGluconatesGluconolactoneMatrix (chemical analysis)Lactones0404 agricultural biotechnologyfoodRheologySkimmed milkGeneticsConfocal laser scanning microscopyFood and NutritionAnimalsFood scienceChemistry0402 animal and dairy sciencefood and beverages04 agricultural and veterinary sciencesHydrogen-Ion ConcentrationMicrostructure040401 food science040201 dairy & animal scienceMilkChemical engineeringAlimentation et NutritionFood TechnologyAnimal Science and ZoologyGasesRheology[SDV.AEN]Life Sciences [q-bio]/Food and NutritionOxidation-Reductionδ lactoneFood Science
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