Search results for "Conclusion"

showing 10 items of 49 documents

Ruolo della working memory e dello stile di risposta Jumping To Conclusions in un campione di pazienti al first episode psychosis

2013

Jumping To Conclusionpsychosisworking memory
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Jumping to conclusions, general intelligence, and psychosis liability: Findings from the multi-centre EU-GEI case-control study

2021

This study was funded by the Medical Research Council, the European Community’s Seventh Framework Program grant [agreement HEALTH-F2-2009-241909 (Project EU-GEI)], São Paulo Research Foundation (grant 2012/0417-0), the National Institute for Health Research (NIHR) Biomedical Research Centre (BRC) at South London and Maudsley NHS Foundation Trust and King’s College London, the NIHR BRC at University College London and the Wellcome Trust (grant 101272/Z/12/Z).

MaleMISCOMPREHENSIONIntelligenceDELÍRIO0302 clinical medicineCognitionSCHIZOPHRENIApsychotic-like experiencejumping to conclusionsApplied PsychologyProblem SolvingRISKeducation.field_of_studyCognitionMiddle Aged16. Peace & justiceCognitive bias3. Good healthFirst episode psychosis; IQ; jumping to conclusions; polygenic risk score; psychotic-like experiences; symptom dimensionsPsychiatry and Mental healthBIASSchizophreniaRELIABILITYFemaleOriginal Articlejumping to conclusion[SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]medicine.symptomClinical psychologyAdultPsychosisFirst episode psychosisAdolescentDISORDERSPopulationREEXAMINATIONDelusionssymptom dimensions03 medical and health sciencesYoung AdultPEOPLEmedicineHumansCognitive DysfunctioneducationDELUSIONAL IDEATIONCognitive deficitpsychotic-like experiencesbusiness.industryCase-control studymedicine.diseaseFirst episode psychosi030227 psychiatryPsychotic DisordersIQCase-Control StudiesJumping to conclusionspolygenic risk scorebusiness030217 neurology & neurosurgeryPsychological medicine
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Identification of calcium sensing receptor (CaSR) mRNA-expressing cells in normal and injured rat brain

2009

Calcium sensing receptor (CaSR), isolated for the first time from bovine and human parathyroid, is a G-protein-coupled receptors that has been involved in diverse physiological functions. At present a complete in vivo work on the identification of CaSR mRNA-expressing cells in the adult brain lacks and this investigation was undertaken in order to acquire more information on cell type expressing CaSR mRNA in the rat brain and to analyse for the first time its expression in different experimental models of brain injury. The expression of CaSR mRNAs was found mainly in scattered cells throughout almost all the brain regions. A double labeling analysis showed a colocalization of CaSR mRNA expr…

Malemedicine.medical_specialtyTime FactorsCentral nervous systemHippocampusCell CountSettore BIO/11 - Biologia MolecolareBiologySettore BIO/09 - Fisiologiachemistry.chemical_compoundSeizuresInternal medicineSettore BIO/10 - BiochimicaCaSRmedicineAnimalsRNA MessengerRats WistarIbotenic AcidMolecular BiologyIn Situ HybridizationNeuronsKainic AcidGeneral NeuroscienceDentate gyrusBrainColocalizationImmunohistochemistryRatsOligodendrogliamedicine.anatomical_structureEndocrinologynervous systemchemistryBrain InjuriesNeurogliaNeurology (clinical)Pyramidal cellCaSR; BrainCalcium sensing receptor (CaSR) isolated for the first time from bovine and human parathyroid is a G-protein-coupled receptors that has been involved in diverse physiological functions. At present a complete in vivo work on the identification of CaSR mRNA-expressing cells in the adult brain lacks and this investigation was undertaken in order to acquire more information on cell type expressing CaSR mRNA in the rat brain and to analyse for the first time its expression in different experimental models of brain injury. The expression of CaSR mRNAs was found mainly in scattered cells throughout almost all the brain regions. A double labeling analysis showed a colocalization of CaSR mRNA expression in neurons and oligodendrocytes whereas it was not found expressed both in the microglia and in astrocytes. One week after kainate-induced seizure CaSR was found in the injured CA3 region of the hippocampus and very interestingly it was found up-regulated in the neurons of CA1-CA2 and dentate gyrus. Similarly 1 week following ibotenic acid injection in the hippocampus CaSR mRNA expression was increased in oligodendrocytes both in the lesioned area and in the contralateral CA1-CA3 pyramidal cell layers and dentate gyrus. One week after needle-induced mechanical lesion an increase of labeled cells expressing CaSR mRNA was observed along the needle track. In conclusion the present results contribute to extend available data on cell type-expressing CaSR in normal and injured brain and could spur to understand the role of CaSR in repairing processes of brain injury.Receptors Calcium-SensingIbotenic acidDevelopmental BiologyAstrocyte
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A review of negotiation outcome: A proposal on delimitation and subsequent assessment in joint venture negotiations

2009

Abstract In this study, we examine the outcomes of negotiation processes in joint ventures. Following a review of negotiation and strategy literature, we propose that satisfaction with the relationship created between partners is the most suitable indicator of negotiation outcome. This indicator is analyzed through the use of two parameters or variables: trust and uncertainty. The analysis is then used to bridge the gap that currently exists in the literature by proposing when a negotiation should be considered successful in joint ventures. One important conclusion of our study is that nonagreement should not always be valued in negative terms as in certain circumstances it can imply the mo…

MarketingNegotiationImportant conclusionPublic AdministrationManagement of Technology and Innovationmedia_common.quotation_subjectPolitical scienceJoint ventureBusiness and International ManagementOutcome (game theory)HumanitiesManagementmedia_commonCanadian Journal of Administrative Sciences / Revue Canadienne des Sciences de l'Administration
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La vessatorietà della provvigione del mediatore in caso di recesso del venditore

2021

La Corte di Cassazione conferma il precedente orientamento favorevole a qualificare come vessatorie le clausole, pattuite nei contratti di mediazione, con le quali le agenzie immobiliari si assicurano il diritto alla provvigione anche in caso di mancata conclusione dell’affare. La soluzione avallata dalla Corte – che nello specifico, per il caso di recesso del venditore, commina la nullita` consumeristica alla clausola con cui il mediatore ottenga un compenso, a prescindere da una commisurazione all’attivita` svolta – si espone, tuttavia, al rischio di traghettare il giudizio di vessatorieta` sulla sponda di un inammissibile sindacato sull’equilibrio economico dello scambio.

Mediazione atipicaSindacato di vessatorietàMandato di mediazione immobiliareClausole vessatorieSquilibrio normativo ed economicoMediazioneSettore IUS/01 - Diritto PrivatoMancata conclusione dell'affareSindacato sulle clausole vessatorieProvvigione
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Sospensione riproduttiva temporanea: etica delle popolazioni e cambiamento climatico

2012

The article defends a proposal of demographic self-limitation that should be realized by the citizens of industrialized countries as a contribution to the reduction of global emissions, for the benefit of future generations and emerging countries. It will also argue that many of the practical objections to the feasibility of this kind of voluntary choice are surmountable, as are some moral objections raised in the name of reproductive freedom and the value of future lives that would not be lived as a result of this choice.

MitigationPopulation Ethics Climate Change Repugnant Conclusion Reproductive Freedom MitigationClimate ChangeRepugnant ConclusionPopulation EthicsPopulation Ethics; Climate Change; Repugnant Conclusion; Reproductive Freedom; MitigationReproductive Freedom
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Pharmacokinetics in Drug Discovery

2007

The aim of this current review is to summarize the present status of pharmacokinetics in Drug Discovery. The review is structured into four sections. The first section is a general overview of what we understand by pharmacokinetics and the different LADMET aspects: Liberation, Absorption, Distribution, Metabolism, Excretion, and Toxicity. The second section highlights the different computational or in silico approaches to estimate/predict one or several aspects of the pharmacokinetic profile of a discovery lead compound. The third section discusses the most commonly used in vitro methodologies. The fourth and last section examines the various approaches employed towards the pharmacokinetic …

Models MolecularProteomicsDrug discoverybusiness.industryManagement scienceComputer aidPharmaceutical ScienceGenomicsPopulation pharmacokineticsPharmacologyModels BiologicalPharmacokineticsPharmaceutical technologyDrug DesignMajor conclusionAnimalsHumansMedicinePharmacokineticsbusinessProtein BindingADMEJournal of Pharmaceutical Sciences
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Association between climate and new daily diagnoses of COVID-19

2020

AbstractBackgroundAlthough evidence is accumulating that climate conditions may positively or negatively influence the scale of coronavirus disease 2019 (COVID-19) outbreaks, uncertainty remains concerning the real impact of climate factors on viral transmission. Methods. The number of new daily cases of COVID-19 diagnosed in Verona (Italy) was retrieved from the official website of Veneto Region, while information on daily weather parameters in the same area was downloaded from IlMeteo website, a renowned Italian technological company specialized in weather forecasts. The search period ranged between March 1 to November 11, 2020. The number of new daily COVID-19 cases and meteorological da…

Multivariate analysisCoronavirus disease 2019 (COVID-19)Leadership and ManagementStrategy and Management2020. The number of new daily COVID-19 cases and meteorological data in Verona were correlated using both univariate and multivariate analysis. Results: The number of daily COVID-19 diagnoses in Verona was positively associated with the number of days in lockdown and humidity1% decrease in humidityWind speedmin and max temperatureand influence the likelihood or course of local COVID-19 outbreaks. Preventive measuresHealth Information Managementa renowned Italian technological company specialized in weather forecasts. The search period ranged between March 1 and November 11mean air temperature1.2% and 5.4% reduction in new COVID-19 daily diagnoses. A significant difference was observed in values of all-weather parameters recorded in Verona between days with &ltHealth Policy1 km/h increase in wind speed and day with rainfall were independently associated with 1.0%Significant differencehumidityUnivariateOutbreakHumidityand inversely correlated with meanmean wind speed and number of days with rainfall. Days of lockdownwhile information on daily weather parameters in the same area was downloaded from IlMeteo websitetesting policies and hospital preparedness should be reinforced during periods of higher meteorological risk and in local environments with adverse climate conditions.Background: Although evidence is accumulating that climate conditions may positively or negatively influence the scale of coronavirus disease 2019 (COVID-19) outbreaks0.3%uncertainty remains concerning the real impact of climate factors on viral transmission. Methods: The number of new daily cases of COVID-19 diagnosed in Verona (Italy) was retrieved from the official website of Veneto RegionGeography100 or ≥100 new daily COVID-19 diagnoses. Conclusions: Climate conditions may play an essential role in conditions of viral transmissionAir temperaturemean wind speed and number of days with rainfall remained significantly associated in multivariate analysis. The four weather parameters contributed to explaining 61% of variance in new daily COVID-19 diagnoses. Each 1% increase in air temperatureBackground: Although evidence is accumulating that climate conditions may positively or negatively influence the scale of coronavirus disease 2019 (COVID-19) outbreaks uncertainty remains concerning the real impact of climate factors on viral transmission. Methods: The number of new daily cases of COVID-19 diagnosed in Verona (Italy) was retrieved from the official website of Veneto Region while information on daily weather parameters in the same area was downloaded from IlMeteo website a renowned Italian technological company specialized in weather forecasts. The search period ranged between March 1 and November 11 2020. The number of new daily COVID-19 cases and meteorological data in Verona were correlated using both univariate and multivariate analysis. Results: The number of daily COVID-19 diagnoses in Verona was positively associated with the number of days in lockdown and humidity and inversely correlated with mean min and max temperature mean wind speed and number of days with rainfall. Days of lockdown mean air temperature humidity mean wind speed and number of days with rainfall remained significantly associated in multivariate analysis. The four weather parameters contributed to explaining 61% of variance in new daily COVID-19 diagnoses. Each 1% increase in air temperature 1% decrease in humidity 1 km/h increase in wind speed and day with rainfall were independently associated with 1.0% 0.3% 1.2% and 5.4% reduction in new COVID-19 daily diagnoses. A significant difference was observed in values of all-weather parameters recorded in Verona between days with <100 or ≥100 new daily COVID-19 diagnoses. Conclusions: Climate conditions may play an essential role in conditions of viral transmission and influence the likelihood or course of local COVID-19 outbreaks. Preventive measures testing policies and hospital preparedness should be reinforced during periods of higher meteorological risk and in local environments with adverse climate conditions.DemographyJournal of Hospital Management and Health Policy
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Viaggi nell’immaginario: il turismo virtuale nel sito UNESCO di Tarragona

2023

Le nuove tecnologie hanno trasformato in modo radicale non solo la geografia come disciplina, ma anche le geografie del mondo. Il digitale ha assunto, infatti, un ruolo di mediazione sempre più pervasivo nella produzione dello spazio, come delle conoscenze e degli immaginari geografici. Le possibilità offerte dal virtuale, in particolare, offrono oggi un contributo decisivo nella comunicazione dei significati attribuiti ai luoghi e rispondono in modo sempre più efficace ai bisogni emergenti del settore turistico. Le esperienze di visita mediate dal digitale mirano a coinvolgere i sensi e risultano efficaci quando promuovono immersioni rigorosamente realistiche. Nel quadro di queste riflessi…

New technologies have radically transformed not only geography as a discipline but also the geographies of the world. Indeed the digital has assumed an increasingly pervasive mediating role in the production of space as of geographic knowledge and imaginaries. The possibilities offered by the virtual in particular now offer a decisive contribution in communicating the meanings attributed to places and respond increasingly effectively to the emerging needs of the tourism sector. Digitally mediated visitor experiences aim to engage the senses and are effective when they promote rigorously realistic immersions. Within the framework of these reflections the paper highlights the renewed relevance of authenticity both of the tourism experience and of cultural heritage in relation to its potential for attraction and proposes a contextualization of the theme in light of the unprecedented opportunities granted by technologies for the creation of virtual and augmented spaces. The proposed discussion is therefore also a journey aimed at exploring authenticity as a tool through which new technologies can effectively mediate a sense of place and foster brand communication of a destination. The case study is the UNESCO site of Tarragona whose most relevant image for urban policies is presented. This shared figuration spatially defined and rooted in a precise historical moment is reconstructed on the one hand through the analysis of functional documentation for the candidacy and on the other by means of a review of mobile applications developed for the promotion of the city's cultural heritage. The proposed journey and exploration of the place return in light of the research data and in conclusion the central role played by digital technologies in mediating the UNESCO imaginary. The forms of virtual tourism in Tarragona confirm that to travel is to experience a text enveloped in time and inscribed in space.Settore M-GGR/01 - Geografia
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S77. JUMPING TO CONCLUSIONS AND FACIAL EMOTION RECOGNITION IMPAIRMENT IN FIRST EPISODE PSYCHOSIS ACROSS EUROPE

2018

Abstract Background Jumping to conclusions (JTC) is a well-established reasoning and data gathering bias found in patients with psychosis even at illness onset (First Episode Psychosis, FEP). Preliminary work in this field focused primarily on the association with delusions, although jumping to conclusions has also been found in non-deluded schizophrenia patients after remission, and in individual with at risk mental state. Moreover, psychotic patients tend to show impairments in social cognition, struggling in identifying, processing and interpreting social clues. Deficits in facial emotion recognition (FER) – a key component of the construct – represent a well-replicated finding in schizo…

Poster Session IIIPsychosiseducation.field_of_studybusiness.industrymedia_common.quotation_subjectPopulationCognitionAngermedicine.diseaseLogistic regressionAbstractsPsychiatry and Mental healthSocial cognitionSchizophreniaJumping to conclusionsMedicinebusinesseducationmedia_commonClinical psychologySchizophrenia Bulletin
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