Search results for "Condition"
showing 10 items of 2530 documents
Mapping routine measles vaccination in low- and middle-income countries
2021
The safe, highly effective measles vaccine has been recommended globally since 1974, yet in 2017 there were more than 17 million cases of measles and 83,400 deaths in children under 5 years old, and more than 99% of both occurred in low- and middle-income countries (LMICs)1–4. Globally comparable, annual, local estimates of routine first-dose measles-containing vaccine (MCV1) coverage are critical for understanding geographically precise immunity patterns, progress towards the targets of the Global Vaccine Action Plan (GVAP), and high-risk areas amid disruptions to vaccination programmes caused by coronavirus disease 2019 (COVID-19)5–8. Here we generated annual estimates of routine childhoo…
Theory-Based Interventions Combining Mental Simulation and Planning Techniques to Improve Physical Activity: Null Results from Two Randomized Control…
2016
Interventions to assist individuals in initiating and maintaining regular participation in physical activity are not always effective. Psychological and behavioral theories advocate the importance of both motivation and volition in interventions to change health behavior. Interventions adopting self-regulation strategies that foster motivational and volitional components may, therefore, have utility in promoting regular physical activity participation. We tested the efficacy of an intervention adopting motivational (mental simulation) and volitional (implementation intentions) components to promote a regular physical activity in two studies. Study 1 adopted a cluster randomized design in wh…
Structural Insight into CVB3-VLP Non-Adjuvanted Vaccine
2020
Coxsackievirus B (CVB) enteroviruses are common pathogens that can cause acute and chronic myocarditis, dilated cardiomyopathy, aseptic meningitis, and they are hypothesized to be a causal factor in type 1 diabetes. The licensed enterovirus vaccines and those currently in clinical development are traditional inactivated or live attenuated vaccines. Even though these vaccines work well in the prevention of enterovirus diseases, new vaccine technologies, like virus-like particles (VLPs), can offer important advantages in the manufacturing and epitope engineering. We have previously produced VLPs for CVB3 and CVB1 in insect cells. Here, we describe the production of CVB3-VLPs with enhanced pro…
Differential memory persistence of odor mixture and components in newborn rabbits: competition between the whole and its parts
2014
Interacting with the mother during the daily nursing, newborn rabbits experience her body odour cues. In particular, the mammary pheromone (MP) contained in rabbit milk triggers the typical behaviour which helps to localize and seize the nipples. It also promotes the very rapid appetitive learning of simple or complex stimuli (odorants or mixtures) through associative conditioning. We previously showed that 24h after MP-induced conditioning to odorants A (ethyl isobutyrate) or B (ethyl maltol), newborn rabbits perceive the AB mixture in a weak configural way, i.e. they perceive the odour of the AB configuration in addition to the odours of the elements. Moreover, after conditioning to the m…
Geochimica e petrografica di black shales del Livello Bonarelli, sezione di Novara di Sicilia (Monte Peloritani), Sicilicia nord-orientale: Implicazi…
2000
Black shales ad alto potenziale petrolifero, alternati ritmicamente a marne e argilliti, affiorano in associazione con Argille Varicolori (Cretaceo-Paleogene) nei pressi di Novara di Sicilia (Monti Peloritani, Sicilia nord-orientale) costituendo l’espressione sedimentaria di un evento anossico con diffusione globale (OAE2), riferibile al Cenomaniano superiore. I depositi corrispondenti a tale evento sono individuati come “Livello Bonarelli”. In detta successione, le alternanze black shales-marne-argilliti si estendono per uno spessore di circa 11 metri passando verso il basso ad alternanze irregolari di calcari marnosi, marne chiare, marne scure, argilliti e calcareniti (spessore ca. 9 m) c…
Il principio di equivalenza delle condizioni
2018
Il principio di equivalenza delle condizioni sancito dall'art. 41 c.p. completa la ricezione da parte dell'ordinamento italiano del modello causale della condicio sine qua non. Tale principio conosce però il temperamento offerto dalla causa prevalente di cui all'art. 41, comma 2, c.p. grazie al quale le valutazioni squisitamente giuridiche riescono a prevale sulle risultanze dello stretto giudizio causale. Il saggio indaga il contenuto e i criteri di tale correzione del giudizio causale. The principle of equivalence of conditions enshrined in art. 41 c.p. completes the reception by the Italian Legal System of the causal model of the condicio sine qua non. However, this principle knows the t…
Performing arts and mediation technology in the period of lockdown
2021
Advancements in digital technologies have become novel ways to enrich communication, expression, and transmission of arts knowledge. Technology is increasingly implemented in the performance space, as a source of inspiration for artists. Especially in this period of lockdown, mediation technology has turned out to be an essential tool for different aspects of social life, as in performing arts. With venues, schools and artistic activities closed, performers, students and spectators have been obliged to keep connecting in remote conditions. This article wants to retrace the aesthetic impact of mediation technology in performing arts during this period of lockdown by focusing on the aspects t…
Conditioned Pain Modulation Is Not Impaired in Individuals with Frozen Shoulder: A Case-Control Study
2021
Frozen shoulder (FS) is a poorly understood condition resulting in substantial shoulder pain and mobility deficits. The mechanisms behind FS are not yet fully understood, but, similar to other persistent pain states, central pain mechanisms may contribute to ongoing symptoms in this population. The objective of this research was to investigate conditioned pain modulation (CPM) in people with FS compared with pain-free individuals. A total of 64 individuals with FS and 64 healthy volunteers participated in this cross-sectional study. CPM was assessed by using the pressure pain threshold (PPT) and an occlusion cuff (tourniquet test) as the test and conditioning stimulus, respectively. The abs…
Relapse risk after autologous transplantation in patients with newly diagnosed myeloma is not related with infused tumor cell load and the outcome is…
2006
BACKGROUND AND OBJECTIVES: This European Group for Blood and Marrow Transplantation (EBMT) multicentre randomized phase III study was designed to assess the safety and efficacy of CD34+ selection in newly diagnosed myeloma patients undergoing autologous transplantation. DESIGN AND METHODS: One hundred and eleven patients responsive to initial chemotherapy were randomized to receive CD34+ selected (arm A) or unselected PBPC (arm B) after conditioning with high-dose melphalan and TBI. ASO-PCR was used to assess purging efficacy and reinfused tumor load. Tumor load could be assessed in 59 patients. RESULTS: CD34+ selection gave a median tumor cell depletion of 2.2 logs (0.77-5.96). No tumor ce…
Predicting COVID-19 booster vaccine intentions.
2022
Achieving broad immunity through vaccination is a cornerstone strategy for long-term management of COVID-19 infections, particularly the prevention of serious cases and hospitalizations. Evidence that vaccine-induced immunity wanes over time points to the need for COVID-19 booster vaccines, and maximum compliance is required to maintain population-level immunity. Little is known of the correlates of intentions to receive booster vaccines among previously vaccinated individuals. The present study applied an integrated model to examine effects of beliefs from multiple social cognition theories alongside sets of generalized, stable beliefs on individuals' booster vaccine intentions. US residen…