Search results for "Condition"
showing 10 items of 2530 documents
Effect of adolescent exposure to WIN 55212-2 on the acquisition and reinstatement of MDMA-induced conditioned place preference.
2009
The present study employs a conditioned place preference procedure (CPP) to examine the effects of exposure to the cannabinoid agonist WIN 55212-2 (WIN) (0.1 and 0.5mg/kg) during adolescence on the reinforcing properties of +/-3,4-methylenedioxymetamphetamine hydrochloride (MDMA) (1.25 and 2.5mg/kg) in mice. On postnatal day (PD) 27, animals received a daily injection of the assigned treatment on 5 consecutive days, and three days later the place conditioning procedure was initiated (PD 35). The results suggest that pre-exposure to cannabinoids strengthens the properties of MDMA and favors reinstatement of the craving for the drug, which endorses the gateway hypothesis.
CB1 cannabinoid receptor-mediated aggressive behavior
2013
This study examined the role of cannabinoid CB1 receptors (CB1r) in aggressive behavior. Social encounters took place in grouped and isolated mice lacking CB1r (CB1KO) and in wild-type (WT) littermates. Cognitive impulsivity was evaluated in the delayed reinforcement task (DRT). Gene expression analyses of monoaminooxidase-A (MAO-A), catechol-o-methyl-transferase (COMT), 5-hydroxytriptamine transporter (5-HTT) and 5-HT1B serotonergic receptor (5HT1Br) in the median and dorsal raphe nuclei (MnR and DR, respectively) and in the amygdala (AMY) were performed by real time-PCR. Double immunohistochemistry studies evaluated COMT and CB1r co-localization in the raphe nuclei and in the cortical (AC…
The Significance of Treasure Hunting: Past and Present
2012
It is certainly insufficient to explain treasure hunting as a reaction to poverty or a form of greed and avarice.1 Avarice has been seen as a part of the human condition and thus as a non-historical, that is, a quasi-anthropological constant. Anthropological constants hardly ever help to explain the behaviour of historical people. In our case, an alleged human tendency to accumulate material wealth does not explain why some people engaged in treasure hunting whereas others did not. Why did people look for treasure? Why did they talk about treasure? Why were they willing to suffer the repeated failure of treasure hunts and continue to look for hidden riches?
Territoires et effets sur les conditions de vie étudiante : étude de cas du dispositif de l’Aide à l’Installation dans un Logement pour les Étudiants…
2020
International audience; L’immolation d’un étudiant précaire à Lyon en automne dernier a ravivé le débat sur les conditions de vie étudiante en France. Dans un contexte de mise en concurrence des villes étudiantes, l’échelle locale est de plus en plus impliquée dans l’amélioration des conditions de vie étudiante et travaille à rendre leur territoire plus attractif pour les étudiants. Un focus est fait sur le dispositif d’Aide à l’Installation dans un Logement pour les Étudiants de la ville de Paris, dispositif qui veut favoriser la mixité sociale étudiante. Une évaluation quantitative du dispositif a été faite à l’aune de la théorie des capabilités. Le dispositif a ainsi augmenté le champ de…
Energy-saving potential of ground source multiple chillers in simple and hybrid configurations for Mediterranean climates
2022
Air conditioning accounts for a large share of energy usage in residential and tertiary sectors. Renewable energy technologies offer promising solutions to reduce the environmental impacts of meeting buildings’ energy loads. The possibility of using the soil as a thermal reservoir for heating and cooling systems has gained growing attention in the last decade due to its high potential for energy saving. In this paper, the benefits achievable using ground source chillers for air conditioning in an office building located in Southern Italy are discussed. A multiple chillers system coupled with a borehole heat exchanger is investigated and compared to conventional air-cooled and water-cooled s…
Experimental characterization of variable-speed packaged rooftop units in presence of evaporator fouling
2022
Variable-speed packaged rooftop units have been increasingly adopted in the commercial sector. If not properly maintained, the fouling of heat exchangers and the improper refrigerant charge could increase energy consumption. In this work, the response of variable-speed rooftop units to evaporator fouling is investigated based on experiments on a variable-speed 17.5 kW rooftop unit. A novel testing procedure is proposed, aimed at covering a broad range of operating conditions by a reduced number of tests. Two opposite cases were investigated: (i) even in presence of fouling, the controller can restore the required cooling capacity, and (ii) the intensity of the fouling does not allow the con…
Explicit Kutta Condition for Unsteady Two-Dimensional High-Order Potential Boundary Element Method
1997
An explicit unsteady pressure Kutta condition is discribed that was directly and efficiently implemented in a time domain high-order potential panel method so as to ensure the pressure equality on the upper and lower surfaces at the trailing edge of the airfoil at each time step.
Algunas reflexiones sobre el alcoholismo femenino
2005
En el presente trabajo se pretende interesar al lector en el análisis del fenómeno del alcoholismo femenino. Se tratan diversos temas como el contexto en el que se socializan las mujeres, teniendo en cuenta los cambios acaecidos en la familia como institución y el rol de la mujer en la sociedad. Otra cuestión con referencia a ese contexto es la prevalencia del consumo de alcohol en el colectivo de mujeres en España y las nuevas tendencias de dicho consumo. Se revisan brevemente los diferentes enfoques teóricos que enmarcan la comprensión e interpretación del alcoholismo, incidiendo en los aspectos de la desviación social y el control social. Para finalizar, algunas consideraciones sobre la …
Parallel fictitious domain method for a non‐linear elliptic neumann boundary value problem
1999
Parallelization of the algebraic fictitious domain method is considered for solving Neumann boundary value problems with variable coefficients. The resulting method is applied to the parallel solution of the subsonic full potential flow problem which is linearized by the Newton method. Good scalability of the method is demonstrated on a Cray T3E distributed memory parallel computer using MPI in communication. Copyright © 1999 John Wiley & Sons, Ltd.
An Integral Version of Ćirić’s Fixed Point Theorem
2011
We establish a new fixed point theorem for mappings satisfying a general contractive condition of integral type. The presented theorem generalizes the well known Ciric's fixed point theorem [Lj. B. Ciric, Generalized contractions and fixed point theorems, Publ. Inst. Math. 12 (26) (1971) 19-26]. Some examples and applications are given.