Search results for "Conducta"

showing 10 items of 611 documents

An overview on chemical structures as ΔF508-CFTR correctors

2019

Deletion of phenylalanine at position 508 (F508del) in the CFTR protein, is the most common mutation causing cystic fibrosis (CF). F508del causes misfolding and rapid degradation of CFTR protein a defect that can be targeted with pharmacological agents termed “correctors”. Correctors belong to various chemical classes but are generally small molecules based on nitrogen sulfur or oxygen heterocycles. The mechanism of action of correctors is generally unknown but there is experimental evidence that some of them can directly act on mutant CFTR improving folding and stability. Here we overview the characteristics of the various F508del correctors described so far to obtain indications on key ch…

Protein FoldingCystic FibrosisCFTR correctorMutantCystic Fibrosis Transmembrane Conductance RegulatorPyrimidinonesmedicine.disease_cause01 natural sciencesF508del-CFTR03 medical and health sciencesMutant proteinDrug DiscoverymedicineAnimalsHumansCFTR030304 developmental biologyPharmacology0303 health sciencesMutationCFTR correctorsbiology010405 organic chemistryChemistryOrganic ChemistryCFTR; CFTR correctors; Cystic fibrosis; Cystic fibrosis transmembrane conductance regulator; F508del-CFTR; Animals; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Humans; Mutation; Protein Folding; Pyrimidinones; ThiazolesGeneral MedicineSettore CHIM/08 - Chimica FarmaceuticaSmall moleculeCystic fibrosis transmembrane conductance regulator0104 chemical sciencesCell biologyThiazolesMechanism of actionCystic fibrosiMutationbiology.proteinmedicine.symptomProtein Aδf508 cftrEuropean Journal of Medicinal Chemistry
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Motivos de la práctica deportiva, bienestar psicológico e inmigración, en practicantes de Street Workout.

2019

El objetivo de la investigación es desarrollar un perl psicosocial de los practicantes de SW y contribuir al conocimiento de esta actividad. Utilizamos un diseño de tipo transversal descriptivo-correlacional, que contó con 216 participantes de entre 18 y 36 años. El 92.6% de la muestra se conformó por hombres y un 21.3% por inmigrantes. Evaluamos los motivos de práctica, bienestar psicológico, las diferencias en función de la situación migratoria y de la práctica de deportes adicionales. Obtuvimos datos sociodemográ cos (sexo, edad, situación sociolaboral y país de origen) y relacionados con la actividad (antigüedad en la práctica, tiempo de entrenamiento y modo de aproximación). Los result…

PsicologiaConducta (Psicologia)
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La presencia del evolucionismo en las Ciencias Sociales y en particular en la Psicología

1992

En el presente trabajo se examina el impacto actual de Charles Darwin en el complejo campo de las ciencias sociales, prestando atención particular a la psicología actual. El método utilizado ha sido el análisis de las citas dirigidas a Darwin en las publicaciones vaciadas por el Social Sciences Citation Index. El objetivo planteado ha sido determinar el número de citas recibidas, precisar su distribución temporal, y consignar las obras más relevantes según el criterio. Además, se analiza el ámbito científico en el que muestran mayor impacto y las revistas máximas citadoras.

PsicologiaEvolució de la conducta
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Transdiagnóstico de las obsesiones y las compulsiones: una propuesta/ The transdiagnostic nature of obsessions and compulsions: a proposal

2018

El propósito de adoptar un enfoque transdiagnóstico en psicopatología es comprender las comunalidades entre trastornos mentales clínicamente diferentes sobre la base de un rango de dimensiones y procesos etiopatogénicos compartidos. Este enfoque es radicalmente diferente al adoptado en los sistemas de diagnóstico psiquiátrico vigentes, basados en ideas y conceptos categoriales que se han mostrado ineficaces en los mismos ámbitos en los que surgieron, es decir, en las ciencias biológicas. En este trabajo revisamos la información empírica disponible sobre la utilidad de enfocar las diferentes psicopatologías del espectro obsesivo, adoptando un planteamiento transdiagnóstico. Para ello, escogi…

PsicologiaPersonalitat sociopatològicaTrastorns de la conducta alimentària
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Análisis del papel de la resiliencia y de las necesidades psicológicas básicas como antecedentes de las experiencias de diversión y aburrimiento en e…

2019

La psicología positiva defiende que las variables que promueven la calidad de la implicación, como la resiliencia y la satisfacción de las necesidades psicológicas básicas, contribuyen a predecir el desarrollo óptimo. Desde el marco de la teoría de la autodeterminación, en el presente estudio se analiza la relación entre la resiliencia, la satisfacción y la frustración de las necesidades psicológicas básicas y las experiencias de diversión y aburrimiento en la práctica deportiva. En el estudio participan 641 jugadoras de fútbol y baloncesto (Medad=14.74±3.91). Los resultados del análisis de ecuaciones estructurales muestran que la resiliencia se asocia positivamente con la satisfacción y ne…

Psicología positivaadaptabilidadResiliencia psicológicaMujersatisfacción030229 sport sciencesDeporteEducation03 medical and health sciences0302 clinical medicineEfectos psicológicosnecesidadDevelopmental and Educational Psychologysexo femeninopsicología de la conducta030217 neurology & neurosurgery
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Normalizing the eating pattern with virtual reality for bulimia nervosa: a case report

2015

AbstractThe aim of the present study was to analyze the effects of a virtual reality (VR) component as a therapeutic tool to normalize eating patterns, as part of the cognitive-behavioral treatment of a bulimia nervosa (BN) patient. Results indicated that the patient made significant progress with her eating habits; binges and vomits were eliminated completely. Moreover, when the VR started the patient avoided food, especially meat (5 over 5), and it was reduction of this avoidance in the lasts sessions (2 and 3 over 5). It was also observed a reduction in the avoidance and the fear of eating (from 10 and 9 to 6 and 5 respectively) and increased the impulse control (from 2 to 7). The patien…

PsychotherapistBulimia nervosaCase studyMotivation to changeVirtual realityTrastornos de la conducta alimentariamedicine.diseaseVirtual realityEstudio de casoRealidad virtualPsychiatry and Mental healthClinical PsychologyGeneral psychopathologySample size determinationEating disordersmedicineDrive for thinnessEating habitsPsychologyBulimia purgative subtypeBulimia nerviosa subtipo purgativoClinical psychologyRevista Mexicana de Trastornos Alimentarios
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Resilience as a predictor of Quality of Life in participants with borderline personality disorder before and after treatment.

2021

Abstract Background Studies have suggested that psychotherapy improves the Quality of Life (QoL) of participants with Borderline Personality Disorder (BPD). However, there are no studies on the differential efficacy of treatments on the QoL of participants with BPD. Moreover, the relationship between QoL and resilience has rarely been studied in participants with BPD. Objectives: a) to examine whether people with BPD have worse QoL than the non-clinical population; b) to examine whether there are statistically significant differences between Dialectical Behavioural Therapy (DBT), Systems Training for Emotional Predictability and Problem Solving (STEPPS), or Cognitive Behavioural Therapy-Tre…

Quality of lifedialectical behavior therapymedia_common.quotation_subjectmedicine.medical_treatmentPopulationSystems training for emotional predictability and problem solvingRC435-571personality disorderTeràpia de la conductabehavioral disciplines and activitiesDialectical behavior therapyQuality of lifeMultivariate analysis of varianceBorderline Personality Disordermental disordersMedicineHumanseducationBorderline personality disorderresiliencePsychological treatmentmedia_commonPsychiatryeducation.field_of_studyCognitive Behavioral TherapyPersonality disorderResiliencebusiness.industryBeck Depression InventoryEmocionspsychological treatmentCognitionmedicine.diseaseDialectical behavior therapyhumanitiesPsychotherapyPsychiatry and Mental healthTreatment Outcomequality of lifePsychotherapy Groupsystems training for emotional predictability and problem solvingPsychological resiliencePersonalitatbusinessClinical psychologyResearch Article
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Pore structure and function of synthetic nanopores with fixed charges: tip shape and rectification properties

2011

We present a complete theoretical study of the relationship between the structure (tip shape and dimensions) and function (selectivity and rectification) of asymmetric nanopores on the basis of previous experimental studies. The theoretical model uses a continuum approach based on the Nernst-Planck equations. According to our results, the nanopore transport properties, such as current-voltage (I-V) characteristics, conductance, rectification ratio, and selectivity, are dictated mainly by the shape of the pore tip (we have distinguished bullet-like, conical, trumpet-like, and hybrid shapes) and the concentration of pore surface charges. As a consequence, the nanopore performance in practical…

Quantitative Biology::BiomoleculesPhysics::Biological PhysicsNanostructureMaterials scienceMechanical EngineeringConductanceBioengineeringNanotechnologyGeneral ChemistryConical surfaceStructure and functionQuantitative Biology::Subcellular ProcessesNanoporeRectificationMechanics of MaterialsChemical physicsGeneral Materials ScienceSurface chargeNanoporous membraneElectrical and Electronic EngineeringNanotechnology
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Two-dimensional model colloids and nano wires: phase transitions, effects of external potentials and quantum effects

2005

Abstract Quantum effects, structures and phase transitions in Nano-systems have been analyzed. An overview is given on the results of our computations on structural and elastic properties of model colloids, on phase transitions of model colloids in external fields, and on structural and electronic properties of stretched atomic wires.

Quantum phase transitionPhase transitionMaterials scienceCondensed matter physicsComputationGeneral Physics and AstronomyConductanceDimensional modelingCondensed Matter::Soft Condensed MatterColloidHardware and ArchitectureQuantum mechanicsNano-Electronic propertiesComputer Physics Communications
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Mindfulness, rumination, and coping skills in young women with Eating Disorders: A comparative study with healthy controls

2019

Eating Disorders (ED) have been associated with dysfunctional coping strategies, such as rumination. Promoting alternative ways of experiencing mental events, based on a mindfulness approach, might be the clue for learning more effective coping and regulatory strategies among young women with ED. This study examined the comparison between patients with ED diagnosis and healthy subjects in mindfulness, rumination and effective coping. In addition, we analyzed the independent association of those with the presence of ED. The study sample was formed by two groups of young women ranged 13-21 years: Twenty-five with an ED diagnosis and 25 healthy subjects. They were assessed by using the Freibur…

Questionnaires050103 clinical psychologyCoping (psychology)MindfulnessEating DisordersEmotionsSocial Sciences0302 clinical medicineCognitionSurveys and QuestionnairesAdaptation PsychologicalMedicine and Health SciencesPsychologyMultidisciplinary05 social sciencesQHealthy subjectsRCognitionEating disordersMeditacióHealth Education and AwarenessResearch DesignMedicineFemalemedicine.symptomPsychologyMindfulnessClinical psychologyResearch ArticleAdolescentScienceMetacognitionDysfunctional familyModels PsychologicalResearch and Analysis MethodsFeeding and Eating Disorders03 medical and health sciencesYoung AdultMental Health and PsychiatrymedicineHumans0501 psychology and cognitive sciencesTrastorns de la conducta alimentàriaBehaviorSurvey ResearchBehavioral DisordersBiology and Life Sciencesmedicine.disease030227 psychiatryHealth CareRumination CognitivePsicologiaSpainCase-Control StudiesRuminationCognitive ScienceMetacognitionNeuroscience
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