Search results for "Cone"

showing 10 items of 772 documents

Antibacterial Activity of Flavonoids Against Methicillin-resistant Staphylococcus aureus strains

2000

An experimental and theoretical study was performed on the anti-staphylococcal activity of 18 natural and synthetic flavonoids against methicillin-resistant Staphylococcus aureus strains. The analysed flavonoids belong to three well-differentiated structural patterns: chalcones, flavanones and flavones. The quantitative analysis of the anti-staphylococcal activity of the compounds was carried out by determining their percent inhibition degree. The hierarchical cluster analysis method was used to analyse the anti-MRSA activity of the compounds. With this methodology, the flavonoids were classified into four groups according to their anti-staphylococcal activity (high, sufficient, intermediat…

Statistics and ProbabilityStaphylococcus aureusChalconeStereochemistryFlavonoidMicrobial Sensitivity Testsmedicine.disease_causeFlavonesGeneral Biochemistry Genetics and Molecular BiologyStructure-Activity Relationshipchemistry.chemical_compoundChalconemedicineAnimalsCluster AnalysisHumansStructure–activity relationshipFlavonoidschemistry.chemical_classificationGeneral Immunology and MicrobiologyApplied MathematicsGeneral MedicineStaphylococcal InfectionsMethicillin-resistant Staphylococcus aureusAnti-Bacterial AgentschemistryBiochemistryStaphylococcus aureusModeling and SimulationMethicillin ResistanceGeneral Agricultural and Biological SciencesAntibacterial activityQuantitative analysis (chemistry)Journal of Theoretical Biology
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On Limiting Fréchet ε-Subdifferentials

1998

This paper presents an e-sub differential calculus for nonconvex and nonsmooth functions. We extend the previous work by Jofre et all to the case where the functions are lower semicontinuous instead of locally Lipschitz.

Statistics::Machine LearningPure mathematicsWork (thermodynamics)Tangent coneMathematics::Optimization and ControlDifferential calculusLimitingLipschitz continuityMathematics
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Rotenoids, Flavonoids, and Chalcones from the Root Bark of Millettia usaramensis.

2015

Five new compounds, 4-O-geranylisoliquiritigenin (1), 12-dihydrousararotenoid B (2), 12-dihydrousararotenoid C (3), 4'-O-geranyl-7-hydroxyflavanone (4), and 4'-O-geranyl-7-hydroxydihydroflavanol (5), along with 12 known natural products (6-17) were isolated from the CH2Cl2/MeOH (1:1) extract of the root bark of Millettia usaramensis ssp. usaramensis by chromatographic separation. The purified metabolites were identified by NMR spectroscopic and mass spectrometric analyses, whereas their absolute configurations were established on the basis of chiroptical data and in some cases also by X-ray crystallography. The crude extract was moderately active (IC50 = 11.63 μg/mL) against the ER-negative…

StereochemistryPlasmodium falciparumMolecular ConformationPharmaceutical Scienceroot barkCrystallography X-Ray01 natural sciencesMillettiaAnalytical ChemistryMillettia usaramensischemistry.chemical_compoundAntimalarialsChalconesDrug DiscoveryPlant BarkHumansta116IC50Nuclear Magnetic Resonance Biomolecularta317metabolitesPharmacologyFlavonoidsChromatographyNatural productbiologyMolecular Structure010405 organic chemistryChemistryPlant ExtractsOrganic ChemistryPlasmodium falciparumChloroquinebiology.organism_classification0104 chemical sciencesMillettia010404 medicinal & biomolecular chemistryChromatographic separationHEK293 CellsComplementary and alternative medicinevisual_artFlavanonesvisual_art.visual_art_mediumPlant BarkMolecular MedicineBarkrotenoidsJournal of natural products
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Photochemical Generation of Cyclophanes from 1,3,5-Trisubstituted Benzenes with Chalcone Chromophores

2007

(E,E,E)-1,3,5-Tricinnamoylbenzene (7a) photodimerizes in solution to the [4.4.4](1,3,5)cyclophane 8a. The process consists of three consecutive steps in which cisoid enone conformations of 7a react in regio- and stereoselective anti-head-to-head cycloadditions. (E,E,E)-1,3,5-Tris(3-oxo-3-phenylpropenyl)benzene (13a), an isomer of 7 with reversed enone units, shows a single [2π+2π] cycloaddition of the same type. Due to steric reasons, it is afterwards not capable of intramolecular processes and oligomerizes by intermolecular photocycloadditions. Photolyses in the crystalline state yield dimers by topochemically controlled syn-head-to-tail processes (7a → 10a, 13a → 15a). An efficient dimeri…

Steric effectsChalconeOlefin fiberChemistryStereochemistryOrganic ChemistryRegioselectivityPhotochemistryCycloadditionchemistry.chemical_compoundIntramolecular forcePhysical and Theoretical ChemistryEnoneCyclophaneEuropean Journal of Organic Chemistry
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Insertion Reactions of Neutral Phosphidozirconocene Complexes as a Convenient Entry into Frustrated Lewis Pair Territory

2016

International audience; Neutral phosphidozirconocene complexes [Cp2Zr(PR2)Me] (Cp=cyclopentadienyl; 1a: R=cyclohexyl (Cy); 1b: R=mesityl (Mes); 1c: R=tBu) undergo insertion into the Zr-P bond by non-enolisable carbonyl building blocks (O=CRR), such as benzophenone, aldehydes, paraformaldehyde or CO2, to give [Cp2Zr(OCRRPR2)Me] (3-7). Depending on the steric bulk around P, complexes 3-7 react with B(C6F5)(3) to give O-bridged cationic zirconocene dimers that display typical frustrated Lewis pair (FLP)/ambiphilic ligand behaviour. Thus, the reaction of {[Cp2Zr(-OCHPhPCy2)][MeB(C6F5)(3)]}(2) (10a) with chalcone results in 1,4 addition of the Zr+/P FLP, whereas the reaction of {[Cp2Zr(-OCHFcPCy…

Steric effectsChalconeStereochemistryzirconiumc-h activation010402 general chemistry01 natural sciencesMedicinal chemistry[ CHIM ] Chemical SciencesCatalysisFrustrated Lewis pairinsertionchemistry.chemical_compoundCyclopentadienyl complexx-ray structuresphosphinidene complexesBenzophenone[CHIM]Chemical SciencesParaformaldehydezr-p bondzirconocene-phosphido complexesmolecular-structure010405 organic chemistryLigandphosphidesOrganic ChemistryCationic polymerizationcrystal-structureGeneral Chemistry0104 chemical sciencesfunctionalized ligandsbis(trimethylsilyl)phosphido complexeschemistryfrustrated Lewis pairsphosphinoaryloxide complexesambiphilic ligands
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The oligomerisation of 3-hydroxy-1-alkynes with palladium(II) diketonates and phosphorus ligands as the catalytic system

1993

Abstract 3-Methylhex-1-yne-3-ol has been oligomerised by use of Pd(II) acetylacetonate with 31 different phosphorus ligands as catalyst, yielding a dimer (2,4-disubstituted but-1-en-3-yne) and a linear trimer (1,4,6-trisubstituted hexa-1,3-dien-5-yne) as the two main products. By input-output relations a variation of the diketonate and the P ligand, as weil as an alteration of the phosphorus/palladium ratio, has been connected with product ratios as dependent variables. Phosphines produced three association steps up to a cone angle of 170°; the third step representing a stop complex. For the first association the activity of the catalytic system and the portion of the 2,4-dimer increased wi…

Steric effectsLigandDimerAcetylacetonechemistry.chemical_elementTrimerMedicinal chemistryCatalysisInorganic Chemistrychemistry.chemical_compoundchemistryMaterials ChemistryOrganic chemistryLigand cone anglePhysical and Theoretical ChemistryPalladiumInorganica Chimica Acta
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Bundlet Model of Single- Wall Carbon, BC2N and BN Nanotubes, Cones and Horns in Organic Solvents

2013

Bundlet Model of Single- Wall Carbon, BC2N and BN Nanotubes, Cones and Horns in Organic Solvents The existence of Single-wall C-nanocones (SWNCs), especially nanohorns (SWNHs) and BC2N/Boron Nitride (BN) analogues is discussed in organic solvents in cluster form. A theory is developed based on the bundlet model, describing distribution function by size. The phenomena present unified explanation in the model, in which free energy of (BC2N/BN )SWNCs involved in cluster, is combined from two components: volume one proportional to the number of molecules n in cluster and surface one, to n1/2. The model enables describing distribution function of (BC2N/BN )SWNC clusters by size. From geometrical…

Structural asymmetryMaterials sciencechemistry.chemical_elementNanotechnologyDisclinationMolecular physicschemistry.chemical_compoundDistribution functionchemistryBoron nitrideCluster (physics)MoleculeLigand cone angleCarbonJournal of Nanomaterials & Molecular Nanotechnology
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Existence, nonexistence and uniqueness of positive solutions for nonlinear eigenvalue problems

2017

We study the existence of positive solutions for perturbations of the classical eigenvalue problem for the Dirichlet $p-$Laplacian. We consider three cases. In the first the perturbation is $(p-1)-$sublinear near $+\infty$, while in the second the perturbation is $(p-1)-$superlinear near $+\infty$ and in the third we do not require asymptotic condition at $+\infty$. Using variational methods together with truncation and comparison techniques, we show that for $\lambda\in (0, \widehat{\lambda}_1)$ -$\lambda>0$ is the parameter and $\widehat{\lambda}_1$ being the principal eigenvalue of $\left(-\Delta_p, W^{1, p}_0(\Omega)\right)$ -we have positive solutions, while for $\lambda\geq \widehat{\…

Sublinear functionMonotonic functionLambda01 natural sciencesOmegaDirichlet distributionsymbols.namesakeFirst eigenvalueP-LaplacianUniqueness0101 mathematicsEigenvalues and eigenvectorsMathematical physicsNonlinear regularityPhysicsApplied Mathematics010102 general mathematicsMathematical analysisVariational methodAnalysiFirst eigenvalue; Generalized picone's identity; Nonlinear maximum principle; Nonlinear regularity; P-Laplacian; Variational methods; Analysis; Applied MathematicsGeneral Medicine010101 applied mathematicsp-LaplaciansymbolsNonlinear maximum principleGeneralized picone's identityAnalysis
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Bundlet Model for Single-Wall Carbon Nanotubes, Nanocones and Nanohorns

2012

This paper discusses the existence of single-wall carbon nanocones (SWNCs), especially nanohorns (SWNHs), in organic solvents in the form of clusters. A theory is developed based on a bundlet model describing their distribution function by size. Phenomena have a unified explanation in bundlet model in which free energy of an SWNC, involved in a cluster, is combined from two components: a volume one, proportional to number of molecules n in a cluster, and a surface one proportional to n1/2. Bundlet model enables describing distribution function of SWNC clusters by size. From purely geometrical differences, bundlet (SWNCs) and droplet (fullerene) models predict different behaviours. The SWNCs…

Surface (mathematics)Materials scienceFullereneDistribution functionlawChemical physicsCluster (physics)MoleculeNanotechnologyLigand cone angleCarbon nanotubeCarbon nanoconelaw.inventionInternational Journal of Chemoinformatics and Chemical Engineering
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Fixed point results on metric-type spaces

2014

Abstract In this paper we obtain fixed point and common fixed point theorems for self-mappings defined on a metric-type space, an ordered metric-type space or a normal cone metric space. Moreover, some examples and an application to integral equations are given to illustrate the usability of the obtained results.

Suzuki type mappingcone metric spaceGeneral MathematicsInjective metric spaceMathematical analysisGeneral Physics and Astronomycommon fixed pointPseudometric spaceFixed pointFixed-point propertyConvex metric spaceIntrinsic metricMetric spaceintegral equationfixed pointmetric-type spaceSettore MAT/05 - Analisi MatematicaMetric differentialMathematicsActa Mathematica Scientia
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