Search results for "Configuration"
showing 10 items of 601 documents
Correlation of the Extent of Fjord-Region Oxidation with DNA Binding and Mutagenicity of the Enantiomeric 11,12-Dihydrodiols of Dibenzo[a,l]pyrene
1996
Abstract In vitro studies on the hepatic biotransformation of the enantiomeric trans-11,12-dihydrodiols of dibenzo[a,l]pyrene (DB[a,l]P) using microsomal fractions of animals pretreated with Aroclor 1254 revealed that the formation of fjord-region dihydrodiol epoxides strongly depends on the absolute configuration of the substrate. Both the (-)-11R,12R- and the (+)-11S,12S-enantiomer are converted diastereoselectively to the (-)- and (+)-anti-dihydrodiol epoxide, respectively, by either rat or mouse liver microsomes. Fjord-region oxidation occurs to greatest extent on incubation of the (-)-11R,12R-dihydrodiol with preparations from rats. This finding is in line with the differences seen for…
Computation of conical intersections by using perturbation techniques
2005
Multiconfigurational second-order perturbation theory, both in its single-state multiconfigurational second-order perturbation theory (CASPT2) and multistate (MS-CASPT2) formulations, is used to search for minima on the crossing seams between different potential energy hypersurfaces of electronic states in several molecular systems. The performance of the procedures is tested and discussed, focusing on the problem of the nonorthogonality of the single-state perturbative solutions. In different cases the obtained structures and energy differences are compared with available complete active space self-consistent field and multireference configuration interaction solutions. Calculations on dif…
Comparison between Different Dynamic Reconfigurations of Electrical Connections for partially shaded PV Modules
2018
This paper presents an economical investigation on the benefits related to the employment of reconfiguration systems for photovoltaic plants. More in detail, different structures of reconfigurators are proposed and, in order to evaluate the economical convenience on their installation, the Net Present Value is used as a validation element. Significant results are carried out from the proposed analysis.
Causal complexity of new product development processes : a mechanism-based approach
2018
The outcomes of new product development (NPD) processes are dependent on the interplay of several interdependent activities. One product development activity can be dependent on the presence or absence of other activities, different kinds of NDP processes may lead to the same outcome, and specific kinds of activities may have a positive effect in one process but no effect in other processes. However, we currently lack means to examine and explain this causal complexity inherent in NPD processes. To address this issue, we introduce mechanism-based approach as a way to capture conjunctural and equifinal causal relations. We build this approach on the philosophical literature on mechanism-base…
The effectiveness of local child weight management programmes: an audit study
2012
Background Many different child weight management programmes exist, with varying degrees of evaluation to provide evidence of their success. The purpose of this research was to use a standardized approach to audit the effectiveness of weight management intervention programmes in the West Midlands region of the UK, specifically to assess the benefits to participating children in terms of health improvement and behaviour change. Methods An audit of seven family-based intervention programmes currently in place in the West Midlands. Programmes were audited against the Standard Evaluation Framework. Results The programmes provided a partial data set relating to a change in weight from the baseli…
Statechart-based design controllers for FPGA partial reconfiguration
2015
Statechart diagram and UML technique can be a vital part of early conceptual modeling. At the present time there is no much support in hardware design methodologies for reconfiguration features of reprogrammable devices. Authors try to bridge the gap between imprecise UML model and formal HDL description. The key concept in author's proposal is to describe the behavior of the digital controller by statechart diagrams and to map some parts of the behavior into reprogrammable logic by means of group of states which forms sequential automaton. The whole process is illustrated by the example with experimental results.
The long-term use of psychiatric services within the Open Dialogue treatment system after first-episode psychosis
2017
AbstractOpen Dialogue is a family-oriented early intervention model for mental health problems developed in the health district of Western Lapland, Finland. In the present study, the aim was to describe how psychiatric services were used in Western Lapland after decades of first-episode psychosis services, and to analyze how baseline characteristics were related to re-admission rates and the total duration of psychiatric treatment in geographical area where Open Dialogue approaches were developed and efforts made to systematically apply them to all psychiatric treatments. The data were obtained from the medical histories of patients who had first-episode psychosis in 1992–2005 and who lived…
Outcomes‐based measurement of public access computing in public libraries
2010
PurposeThis paper seeks to present a methodology for measuring the outcomes of public access computing as well as presenting and comparing the main results of baseline studies conducted in Lithuania and Latvia.Design/methodology/approachBoth baseline studies use a combination of quantitative and qualitative methods and both include multi‐perspective, longitudinal design and nation‐wide samples.FindingsThe benefits that users can gain from using PAC in public libraries include access to ICT, technology training and assistance, expanded employment opportunities, conducting commercial transactions, access to and assistance with local, state and federal government electronic services, and suppo…
Defining moderate asthma exacerbations in clinical trials based on ATS/ERS joint statement
2015
Background Exacerbations are a key outcome in clinical research, providing patient-relevant information about symptomatic control, health state and disease progression. Generally considered as an episode of (sub)acute deterioration of respiratory symptoms, a precise, clinically useful definition is needed for use in clinical trials. Aim and methods Focussing on moderate exacerbations, this opinion piece reviews landmark trials and current guidelines to provide a practical definition of a moderate exacerbation. Specifically, we adapt the ATS/ERS consensus statement of terminology Reddel et al. (2009) [1] which provides a conceptual (or 'theoretical') definition for moderate exacerbations, to…
Special arrangements of lines: Codimension 2 ACM varieties in P 1 × P 1 × P 1
2019
In this paper, we investigate special arrangements of lines in multiprojective spaces. In particular, we characterize codimension 2 arithmetically Cohen–Macaulay (ACM) varieties in [Formula: see text], called varieties of lines. We also describe their ACM property from a combinatorial algebra point of view.