Search results for "Context"
showing 10 items of 6304 documents
The Neutrophil Secretome as a Crucial Link between Inflammation and Thrombosis
2021
Cardiovascular diseases are a leading cause of death. Blood–cell interactions and endothelial dysfunction are fundamental in thrombus formation, and so further knowledge of the pathways involved in such cellular crosstalk could lead to new therapeutical approaches. Neutrophils are secretory cells that release well-known soluble inflammatory signaling mediators and other complex cellular structures whose role is not fully understood. Studies have reported that neutrophil extracellular vesicles (EVs) and neutrophil extracellular traps (NETs) contribute to thrombosis. The objective of this review is to study the role of EVs and NETs as key factors in the transition from inflammation to thrombo…
Synthesis and Evaluation of a Novel Series of Pyrrolizine Derivatives as Dual Cyclooxygenase-1 and 5-Lipoxygenase Inhibitors
1997
The aim of our study was to investigate structure activity relationship following the replacement of the 6-phenyl substituent at the 6,7-diaryl-2,3-dihydropyrrolizine template by various heteroaromatic residues. In this context we developed a new, efficient, and highly sensitive test method for the screening of dual cyclooxygenase-1 (COX-1) and 5-lipoxygenase (5-LOX) inhibitors. We used human platelets as a source of COX-1 and human PMNLs as a source of 5-LOX. Both cell types were isolated from the same volume of blood. PGE2 and LTB4 respectively were determined by highly selective and sensitive ELISA kits, using monoclonal antibodies. For a single determination at most 0.5 mL whole blood i…
On the design of pervasive computing applications based on Bluetooth and a P2P concept
2006
As an example of implementing the pervasive computing, we developed an application framework to deploy an easy, spontaneous, and infrastructureless network. We selected the Bluetooth technology with the peer-to-peer (P2P) concept to develop an experimental application which enables peers to exchange their resources. Overall network architecture and the prototype application are presented. We selected a small test-bed and simulation to evaluate the overall performance and system behaviour. We measured and present our findings in term of the duration of inquiry procedure and the throughput, according to various experimental parameters such as physical distance between nodes and their speeds.
Three Step Bluetooth Positioning
2005
This paper discusses a three step procedure to perform high definition positioning by the use of low cost Bluetooth devices. The three steps are: Sampling, Deployment, and Real Time Positioning. A genetic algorithm is discussed for deployment optimization and a neural network for real time positioning. A case study, along with experiments and results, are finally discussed dealing with a castle in Sicily where many trials were carried out to the end of arranging a positioning system for context aware service provision to visitors.
Factors Influencing Accounting Outsourcing Practices among SMEs in Pakistan Context: Transaction Cost Economics (TCE) and Resource-Based Views (RBV) …
2014
Published version of an article from the journal:International Journal of Business and Management. Also available from the publisher:http://dx.doi.org/10.5539/ijbm.v9n7p19 The present study was conducted to identify factors that affect Pakistani manufacturing SMEs decisions to outsource management accounting practices in terms of transaction cost economics (TCE) and resource-based view (RBV). A survey of 302 SMEs was carried out using convenience sampling, a personal interview owners/managers/CFOs located in 9 major cities of Pakistan. Our multiple regression analysis revealed that the frequency of non-routine tasks, asset specificity, opportunism, trust in accountant and competition has a …
Osteoporosis, densidad mineral ósea y complejo CKD-MBD (I): consideraciones diagnósticas
2018
Resumen: Osteoporosis (OP) y enfermedad renal crónica (ERC) influyen de manera independiente en la salud ósea y cardiovascular. Un número significativo de pacientes con ERC, especialmente desde estadios 3a a 5D, presentan una disminución significativa de la densidad mineral ósea condicionando un alto riesgo de fractura y un incremento importante de la morbimortalidad asociada. Independientemente de la OP clásica asociada a edad y/o sexo, las propiedades mecánicas del hueso se encuentran afectadas adicionalmente por factores intrínsecos a la ERC («OP urémica»). En la primera parte de esta revisión, analizaremos conceptos generales sobre densidad mineral ósea, OP y fracturas, en gran parte in…
The border effect in Spain: The Basque Country case
2006
Gil-Pareja S., Llorca-Vivero R. and Martinez-Serrano J. A. (2006) The border effect in Spain: the Basque Country case, Regional Studies 40, 335–345. This paper investigates the border effect on the Basque Country's trade, using a sample of 28 Organization for Economic Co-operation and Development (OECD) countries between 1995 and 2001. The results indicate that after controlling for market size and distance, the Basque Country trades between 12 and 16 times more with the rest of Spain than it does with any other country. The Spanish bias is lower in the case of the Basque Country's exports than in the case of imports. With respect to the time evolution, the results show a downward trend. Th…
Contextualización iconográfica e intervención en las pinturas murales de la Capilla de la Comunión de la iglesia parroquial de san Nicolás de Bari y …
2018
“Two Schools under one Roof” in Bosnia and Herzegovina: Exploring the challenges of group identity and deliberative values among Bosniak and Croat st…
2014
Abstract The purpose of this study was to explore the challenge of engaging Bosniak and Croat students in Bosnia and Herzegovina (BiH) in deliberative democracy within the context “two schools under one roof,” students receiving education in the same school building, yet attending separate classes and following distinct curricula. Findings suggest that group identity for Bosniak students was strongly tied to “being Bosnian” while Croat students expressed ambivalence and unease about their identity, balancing feelings between having their home in BiH and maintaining their Croat roots. The students’ relationships were complicated by an imbalance in perceptions of power, discriminatory attitud…
Left braces and the quantum Yang-Baxter equation
2019
[EN] Braces were introduced by Rump in 2007 as a useful tool in the study of the set-theoretic solutions of the Yang¿Baxter equation. In fact, several aspects of the theory of finite left braces and their applications in the context of the Yang¿Baxter equation have been extensively investigated recently. The main aim of this paper is to introduce and study two finite brace theoretical properties associated with nilpotency, and to analyse their impact on the finite solutions of the Yang¿Baxter equation.