Search results for "Conti"

Systematic review and meta-analysis of the efficacy and safety of minocycline in schizophrenia

2017

ObjectiveOur aim was to perform an updated systematic review and meta-analysis on the efficacy and safety of adjunctive minocycline as a treatment of schizophrenia.MethodsWe conducted a PubMed/Scopus database search from inception to 3 February 2016 for randomized, placebo-controlled trials (RCTs), open non-randomized studies, and case reports/series evaluating minocycline in patients with schizophrenia. Random-effects meta-analysis of positive, negative, depressive, and cognitive symptom rating scales, discontinuation and adverse effects rates calculating standardized mean difference (SMD), and risk ratios±95% confidence intervals (CI95%) were calculated.ResultsSix RCTs were eligible (mino…

Salt exploitation, communication routes and territory during the Iron Age around the Cabriel river valley

2020

La sal era un recurso fundamental en la economía de las sociedades antiguas y cada vez tenemos más datos sobre su aprovechamiento y explotación durante la Edad del Hierro en ámbito peninsular. La comarca de Requena-Utiel, en el interior de la provincia de Valencia, presenta la mayor abundancia de salinas continentales históricas del territorio valenciano. Por otro lado, en La Manchuela conquense se localiza la importante mina de sal de Minglanilla-La Pesquera. El hallazgo de material arqueológico ibérico en algunas de estas explotaciones sirve como punto de partida para analizar sus características y ver cómo pudieron quedar integradas en el patrón de asentamiento, así como en una densa red…

Nuevas faunas de micromamíferos del Terciario continental de la Depresión Intermedia (provincia de Cuenca, España centro-oriental)

1986

In this paper the fossil content of nine new micromammal bearing localities and that of 15 levels in a borehole from the Loranca Basin (eastern Tague Basin, Prov. of Cuenca) is described. The age ranges from early Arvernian (Late Oligocene) to Turolian (Late Miocene). 47 rodent and lagomorph taxons have been found which are arranged in 8 biostratigraphic units. The Loranca-2 borehole contains 15 fossiliferous levels covering the Upper Oligocene/Lower Miocene. These additional data complete the faunal sequence published by Díaz & López(1919). The stratigraphic framework of the basin needs a revision because of the new faunal data.<br><br>Se presenta una serie de 9 nuevos yaci…

Evoluzione di sistemi deposizionali di piattaforma continentale durante il Pleistocene superiore - Olocene: analisi sedimentologica di due carote pre…

2016

E’ stato condotto uno studio sedimentologico di due carote prelevate nell’offshore della Sicilia settentrionale allo scopo di analizzare i cambiamenti di regime deposizionale verificatisi nel Pleistocene superiore - Olocene. Sulle due carote, provenienti dal Golfo di Termini Imerese (2,74 m di lunghezza, profondità -126 m) e dalla Baia di Carini (1,35 m di lunghezza, profondità -194 m), sono state anche eseguite analisi geochimiche e micropaleontologiche. Da un punto di vista granulometrico in entrambe le carote si può notare che la parte inferiore è principalmente costituita da una granulometria grossolana (ghiaia, ghiaia sabbiosa) che passa ad una granulometria di tipo argillo-siltosa nel…

First Evidence of Contourite Drifts in the North-Western Sicilian Active Continental Margin (Southern Tyrrhenian Sea)

2021

We present the results of an integrated geomorphological and seismo-stratigraphic study based on high resolution marine data acquired in the north-western Sicilian continental margin. We document for the first time five contourite drifts (marked as EM1a, EM2b, EM2, EM3a, and EM3b), located in the continental slope at depths between ca. 400 and 1500 m. EM1a,b have been interpreted as elongated mounded drifts. EM1a,b are ca. 3 km long, 1.3 km wide, and have a maximum thickness of 36 m in their center that thins northwards, while EM1b is smaller with a thickness up to 24 m. They are internally characterized by mounded seismic packages dominated by continuous and parallel reflectors. EM2 is loc…

New seismological and geological-structural contributions to the support of a seismotectonic model of the hinge area between northern Sicily and sout…

2012

Understanding the sense of community and continuance intention in virtual communities: The role of commitment and type of community

2019

Virtual communities (VCs) have become essential in current organizations and society, and so their sustainability is a topic of interest for researchers and practitioners. We focus on the sense of virtual community (SoVC) and commitment as relevant antecedents in achieving the success and maintenance of different types of VCs (communities of interest, virtual learning communities, and virtual communities of practice). Specifically, this study examines a moderated mediation model in which the type of virtual community moderates the indirect effect of a SoVC on the intention to continue through the perceived commitment of the users of the VC. The sample consists of 299 members of Virtual comm…

Managing Continuous Digital Service Innovation for Value Co-Creation

2023

Service organizations across various industries are increasingly implementing continuous development methods and practices to transform their digital service innovation and development processes. Consequently, continuous digital service innovation (DSI) has become a way to react to today’s dynamic markets by proposing value to customers quickly while maintaining service quality. However, little is known about how organizations can enable value co-creation (VCC) in their continuous DSI processes. We fill this gap in the literature by focusing on organizational-level continuous DSI processes. Based on findings from 23 industry informants from six Finnish digital service organizations, we pres…

Estudio comparativo de la combinación de diferentes modos de administración de anestésicos locales en la analgesia del parto

2020

La analgesia epidural es una de las técnicas más demandadas y por ello dicha analgesia ha ido evolucionando en los últimos años. Recientemente se ha desarrollado el modo PIEB (Programmed Intermittent Epidural Boluses) que puede reducir el consumo de anestésico local y así minimizar consecuencias indeseables tales como la cardio o la neurotoxicidad. En el año 2012 la compañía Smiths Medical lanzó al mercado un sistema de infusión ambulatoria CADD®-Solis versión software 3.0 de la generación de bombas de infusión CADD® que permite combinar varios modos de administración del anestésico local en el espacio epidural, hasta ahora no utilizados juntos ya que no existía en el mercado una bomba con …

Omalizumab outcomes for up to 6 years in pediatric patients with severe persistent allergic asthma

2021

BACKGROUND: Various studies have assessed omalizumab outcomes in the clinical practice setting but follow-up and/or number of patients included were limited. We aim to describe the long-term outcomes of pediatric patients with severe persistent allergic asthma receiving omalizumab in the largest real-life cohort reported to date. METHODS: ANCHORS was a multicenter, observational, retrospective cohort study conducted in 25 Pediatric Allergy and Pulmonology units in Spain. We collected data of patients < 18 years and initiating omalizumab between 2006 and 2018, from the year prior to omalizumab initiation to discontinuation or last available follow-up. The primary outcome was the evolution of…