Search results for "Contraction"

showing 10 items of 1092 documents

Changes in motor unit characteristics after eccentric elbow flexor exercise

2010

Morphological evidence suggests that fast-twitch fibers are prone to disruption of their membrane structures by eccentric exercise. However, it is unclear how this is reflected in the discharge rate and action potential propagation of individual motor units, especially at high contraction levels. High-density surface electromyograms were recorded from biceps brachii muscle and decomposed to individual motor unit action potentials at isometric contraction levels between 10% and 75% of maximal voluntary contraction (MVC) before intermittent maximal elbow flexor eccentric exercise, and two hours (2H), two days (2D) and four days (4D) post-exercise. Maximal voluntary force decreased by 21.3±5.6…

medicine.medical_specialtyContraction (grammar)medicine.diagnostic_testMuscle fatigueAction potentialbusiness.industryPhysical Therapy Sports Therapy and Rehabilitation030229 sport sciencesElectromyographyIsometric exerciseAnatomyMotor unit03 medical and health sciences0302 clinical medicineInternal medicinemedicineCardiologyEccentricOrthopedics and Sports MedicineExercise physiologybusiness030217 neurology & neurosurgeryScandinavian Journal of Medicine & Science in Sports
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Increased Joint Mobility Is Associated With Impaired Transversus Abdominis Contraction.

2020

Mitchell, UH, Owen, PJ, Rantalainen, T, and Belavý, DL. Increased joint mobility is associated with impaired transversus abdominis contraction. J Strength Cond Res 36(9): 2472-2478, 2022-Increased joint mobility is a risk factor for joint injury, but muscle function may be able to compensate for it. Current evidence suggests reduced force production capacity in people with hypermobility. However, little is known about the lumbar spine. The purpose of this cross-sectional study was to assess whether there was a link between joint mobility and transverse abdominis and multifidus muscles contraction, muscles ascribed a core-stability role. Using a modified quantitative version of the Beighton …

medicine.medical_specialtyContraction (grammar)medicine.diagnostic_testbusiness.industryParaspinal MusclesPhysical Therapy Sports Therapy and RehabilitationMagnetic resonance imagingGeneral MedicineMiddle AgedLow back painTrunkMultifidus musclePhysical medicine and rehabilitationCross-Sectional StudiesStatistical significanceMedicineHumansOrthopedics and Sports MedicineTransversus abdominismedicine.symptomIncreased joint mobilitybusinessLow Back PainAbdominal MusclesMuscle ContractionJournal of strength and conditioning research
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Changes in gallbladder motor function during the female cycle — a risk factor leading to gallstone formation?

1982

The gallbladder volume of eight women with stable cycles was determined by sonography. Furthermore, gallbladder contraction — following an orally administered fatty meal and the spontaneous refilling of the empty gallbladder — was quantitatively examined. The formula of a rotation ellipsoid, which has been proven to be adequately accurate in in vitro studies, was used for calculating the gallbladder volume. In the gestagen phase (21st or 22nd day) the intraindividual studies showed greater fasting volumes, higher residual volumes after contraction, slower gallbladder emptying, and retarded refilling of the empty gallbladder as compared to the estrogen phase (12th or 13th day). The hormonall…

medicine.medical_specialtyContraction (grammar)medicine.drug_classbusiness.industryGallbladderGallbladderGeneral MedicineGastroenterologyMotor functionMenstruationmedicine.anatomical_structureCholelithiasisEstrogenInternal medicineDrug DiscoverymedicineGallbladder contractionHumansMolecular MedicineFatty mealFemaleGallbladder EmptyingbusinessGenetics (clinical)UltrasonographyKlinische Wochenschrift
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Changes in neural drive to calf muscles during steady submaximal contractions after repeated static stretches

2021

Key points: Repeated static-stretching interventions consistently increase the range of motion about a joint and decrease total joint stiffness, but findings on the changes in muscle and connective-tissue properties are mixed. The influence of these stretch-induced changes on muscle function at submaximal forces is unknown. To address this gap in knowledge, the changes in neural drive to the plantar flexor muscles after a static-stretch intervention were estimated. Neural drive to the plantar flexor muscles during a low-force contraction increased after repeated static stretches. These findings suggest that adjustments in motor unit activity are necessary at low forces to accommodate reduct…

medicine.medical_specialtyContraction (grammar)neural drivePhysiologySpike trainIsometric exerciseStatic stretchingPhysical medicine and rehabilitationmotor unitIsometric ContractionMuscle Stretching ExercisesmedicineHumansMuscle SkeletalUnit functionbusiness.industryElectromyographymusculoskeletal systembody regionsMotor unitTorqueJoint stiffnessmedicine.symptomstretchbusinessRange of motionSettore M-EDF/01 - Metodi E Didattiche Delle Attivita' MotorieMuscle Contraction
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Effect of inhibition of the electrogenic Na+/K+ pump on the mechanical activity in the rat uterus.

1996

The effects of ouabain and K(+)-free solution were studied in estrogen-primed rat uterine strips under resting tone or repeatedly stimulated with KCl, acetylcholine or oxytocin applied for 20 minutes at 60 minute intervals. These effects were compared with those of the K+ channel opener cromakalim. In preparations under resting tone, ouabain (0.1 mM and 0.3 mM) induced rhythmic contractions which disappeared after 20-30 minutes whereas at a higher concentration (1 mM) it evoked a rapid, phasic response followed by a small tonic contraction. Exposure of the strip to a K(+)-free solution induced either rhythmic waves, which ceased after 8-10 minutes, or a single phasic contraction which was f…

medicine.medical_specialtyCromakalimPotassium ChannelsIn Vitro TechniquesOxytocinOuabainchemistry.chemical_compoundUterine ContractionInternal medicinemedicineAnimalsPharmacology (medical)BenzopyransPyrrolesNa+/K+-ATPaseEnzyme InhibitorsRats WistarOuabainPharmacologyTetraethylammoniumVoltage-dependent calcium channelUterusMyometriumPotassium channel blockerAcetylcholineRatsEndocrinologychemistryCalciumFemalemedicine.symptomSodium-Potassium-Exchanging ATPaseCromakalimmedicine.drugMuscle contractionFundamentalclinical pharmacology
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Effects of nicotine receptor agonists on acetylcholine release from the isolated motor nerve, small intestine and trachea of rats and guinea-pigs

1992

The effects of nicotine receptor agonists on the release of [3H]acetylcholine from the phrenic nerve, the small intestine and the trachea were investigated to characterize neuronal nicotine receptors within the peripheral nervous system. Contraction of the indirectly-stimulated hemidiaphragm was recorded to investigate desensitization of the postsynaptic muscular nicotine receptors. Nicotine, cytisine, 1,1-dimethyl-4-phenylpiperazinium and 2-(4-aminophenyl)-ethyl-trimethyl-ammoniumiodide caused a concentration-dependent (0.1-30 microM) increase in evoked [3H]acetylcholine release from the phrenic nerve, whereby bell-shaped concentration-response curves were obtained. The rank order of decre…

medicine.medical_specialtyDiaphragmGuinea PigsMyenteric PlexusMotor nerveReceptors NicotinicMotor EndplateNicotineCytisinechemistry.chemical_compoundPostsynaptic potentialInternal medicineIntestine SmallDrug DiscoverymedicineAnimalsGenetics (clinical)Phrenic nerveDose-Response Relationship DrugMuscle SmoothGeneral MedicineAcetylcholineStimulation ChemicalRatsPhrenic NerveTracheaEndocrinologymedicine.anatomical_structureParasympathomimeticschemistryPeripheral nervous systemMolecular Medicinemedicine.symptomSecretory RateAcetylcholineMuscle Contractionmedicine.drugMuscle contractionThe Clinical Investigator
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D1 receptors play a major role in the dopamine modulation of mouse ileum contractility

2010

Since the role of dopamine in the bowel motility is far from being clear, our aim was to analyse pharmacologically the effects of dopamine on mouse ileum contractility. Contractile activity of mouse ileum was examined in vitro as changes in isometric tension. Dopamine caused a concentration-dependent reduction of the spontaneous contraction amplitude of ileal muscle up to their complete disappearance. SCH-23390, D1 receptor antagonist, which per se increased basal tone and amplitude of spontaneous contractions, antagonized the responses to dopamine, whilst sulpiride or domperidone, D2 receptor antagonists, were without effects. The application of both D1 and D2 antagonists had additive effe…

medicine.medical_specialtyDopamineMouse ileumD1 receptorIn Vitro TechniquesSettore BIO/09 - FisiologiaEnteric Nervous SystemPotassium channelsContractilityMicechemistry.chemical_compoundDopamine receptor D1IleumDopamineInternal medicineDopamine receptor D2medicineAnimalsPharmacologySCH-23390Dose-Response Relationship DrugReceptors Dopamine D1BenzazepinesAdenosine receptorContractile activityD2 receptorDopamine D2 Receptor AntagonistsEndocrinologychemistryDopamine receptorDopamine AntagonistsEndogenous agonistAdenylyl CyclasesMuscle Contractionmedicine.drugPharmacological Research
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Body mass reduction markedly improves muscle performance and body composition in obese females aged 61-75 years: comparison between the effects exert…

2004

OBJECTIVE: To investigate the effectiveness of a body mass reduction programme entailing diet caloric restriction and moderate physical activity with or without supplementary treatment with recombinant (r) GH or steroids to improve body composition and muscle performance in severely obese women aged 61-75 years. METHODS: Twenty women were randomly assigned to one of three groups: body mass reduction alone; body mass reduction plus rGH; body mass reduction plus nandrolone undecanoate. Body composition, isotonic muscle strength and anaerobic power output during jumping were determined before and after the 3-week period. RESULTS: Whatever the experimental group considered, body mass (P<0.01…

medicine.medical_specialtyDoseStrength trainingEndocrinology Diabetes and Metabolismmedicine.disease_causeBody Mass IndexEndocrinologyJumpingInternal medicinemedicineHumansNandroloneTestosteroneIsotonic ContractionObesityInsulin-Like Growth Factor IExerciseAgedNandrolone undecanoatebusiness.industryGeneral MedicineLuteinizing HormoneMiddle Agedmedicine.diseaseCombined Modality TherapyObesityEndocrinologyNandroloneGrowth HormoneBody CompositionFemaleFollicle Stimulating HormonebusinessBody mass indexAnaerobic exercisemedicine.drugEuropean Journal of Endocrinology
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Antihistaminic and anticholinergic activities of mequitazine in comparison with clemizole

1988

Abstract The antihistamine and anticholinergic properties of mequitazine have been investigated and compared with those of clemizole. Both mequitazine and clemizole antagonized the effect of histamine in guinea-pig ileum competitively, the pA2 values calculated by Schild plot were 9.95 ± 0.44 for mequitazine and 10.54 ± 0.44 for clemizole. Mequitazine at 10−7 M produced a parallel shift of the dose-response curve to acetylcholine in the rat duodenum, clemizole and the lower doses of mequitazine failed to modify the effect of acetylcholine. The potency of mequitazine and clemizole as H1-histamine blockers is similar, but only mequitazine at highest concentration used showed anticholinergic a…

medicine.medical_specialtyDuodenummedicine.drug_classmedicine.medical_treatmentGuinea PigsPharmaceutical ScienceIn Vitro TechniquesBiologyParasympatholyticchemistry.chemical_compoundPhenothiazinesInternal medicinemedicineAnticholinergicAnimalsPotencyMequitazinePharmacologyParasympatholyticsMuscle SmoothRats Inbred StrainsAcetylcholineRatsClemizoleSchild regressionEndocrinologychemistryHistamine H1 AntagonistsBenzimidazolesAntihistamineHistamineHistamineMuscle Contractionmedicine.drugJournal of Pharmacy and Pharmacology
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Über das Verhalten von glatter Muskulatur während Kalium-Verarmung und -Akkumulation

1961

The isolated rat uterus looses potassium in potassium-free Tyrode. During this process, the muscle is more easily excitable, and a slowly developing contracture is produced. If potassium is then made available, the muscle relaxes rapidly and spontaneous contractions temporarely cease.

medicine.medical_specialtyEasily excitablePhysiologyChemistryPotassiumClinical Biochemistrychemistry.chemical_elementHuman physiologyEndocrinologyPhysiology (medical)Internal medicineRat uterusmedicineSpontaneous contractionPotassium deficiencyContracturemedicine.symptomPflüger's Archiv für die gesamte Physiologie des Menschen und der Tiere
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