Search results for "Contrast agent"

showing 6 items of 36 documents

Imaging findings of hepatic focal nodular hyperplasia in Gd-EOB-DTPA vs Gd-BOPTA -enhanced MR: preliminary results.

2009

focal nodular hyperplasia hepatocellular-specific contrast agent
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Texture analysis in susceptibility-weighted imaging may be useful to differentiate acute from chronic multiple sclerosis lesions.

2020

To evaluate the diagnostic performance of texture analysis (TA) applied on non-contrast-enhanced susceptibility-weighted imaging (SWI) to differentiate acute (enhancing) from chronic (non-enhancing) multiple sclerosis (MS) lesions. We analyzed 175 lesions from 58 patients with relapsing-remitting MS imaged on a 3.0 T MRI scanner and applied TA on T2-w and SWI images to extract texture features. We evaluated the presence or absence of lesion enhancement on T1-w post-contrast images and performed a computational statistical analysis to assess if there was any significant correlation between the texture features and the presence of lesion activity. ROC curves and leave-one-out cross-validation…

AdultMalemedicine.medical_specialtyAdolescentContrast Media030218 nuclear medicine & medical imagingLesion03 medical and health sciencesYoung Adult0302 clinical medicineMultiple Sclerosis Relapsing-RemittingImage Processing Computer-AssistedMedicineHumansMultiple sclerosiRadiology Nuclear Medicine and imagingDiagnosis Computer-AssistedLeast-Squares AnalysisNeuroradiologyAgedRetrospective Studiesmedicine.diagnostic_testReceiver operating characteristicbusiness.industryMultiple sclerosisUltrasoundReproducibility of ResultsMagnetic resonance imagingGeneral MedicineMiddle Agedmedicine.diseaseMagnetic Resonance ImagingRegressionLogistic modelsContrast agentROC Curve030220 oncology & carcinogenesisArea Under CurveSusceptibility weighted imagingAcute DiseaseChronic DiseaseRegression AnalysisFemaleRadiologymedicine.symptomSettore MED/36 - Diagnostica Per Immagini E RadioterapiabusinessEuropean radiology
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Porphyrines et tétraazamacrocycles dérivés du DOTA : association de deux ligands pour la chélation de métaux d'intérêt en imagerie médicale multimoda…

2012

The goal of my PhD thesis was to synthesize new molecules, which give access to heterobimetallic complexes with interesting properties for multimodal imaging. In this manuscript, several main points have been studied. The first part of this work concerns the synthesis and characterization of ligands. We describe here the synthesis of five new ligands based on the association of one porphyrin and one or several cyclen derivatives. Those ligands are water-soluble. During the synthesis, we have targeted improvements to our work and developed a new synthetic pathway, which allowed us to obtain one ligand incorporating a porphyrin, a cyclen derivative and a free amine function. This function cou…

Complexes hétérobimétalliquesPorphyrinsHeterobimetallic complexesGadoliniumContrast agentsRelaxivity studiesIRM / PETPorphyrinesBODIPY[ CHIM.OTHE ] Chemical Sciences/Other[ SDV.MHEP ] Life Sciences [q-bio]/Human health and pathologyMultimodal imagingMRI / PETChimie “click”[SDV.MHEP] Life Sciences [q-bio]/Human health and pathologyAgents de contrasteTétraazamacrocyclesTransferts d’énergieTetraazamacrocyclesEtudes de relaxivitéDOTAImagerie multimodale[CHIM.OTHE] Chemical Sciences/OtherEnergy transfer“Click” chemistry[CHIM.OTHE]Chemical Sciences/Other[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
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Aggressive Angiomyxoma: unusual pelvic mass

2016

Learning objectives Background Findings and procedure details Conclusion Personal information References

Angiomyxomagenetic structureseducationMRSettore MED/36 - Diagnostica Per Immagini E RadioterapiaContrast agent-intravenousPelvisCancer
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Holmium(III) Single-Ion Magnet for Cryomagnetic Refrigeration Based on an MRI Contrast Agent Derivative

2021

The coexistence of field-induced blockage of the magnetization and significant magnetocaloric effects in the low-temperature region occurs in a mononuclear holmium(III) diethylenetriamine-N,N,N′,N″,N″-pentaacetate complex, whose gadolinium(III) analogue is a commercial MRI contrast agent. Both properties make it a suitable candidate for cryogenic magnetic refrigeration, thus enlarging the variety of applications of this simple class of multifunctional molecular nanomagnets.

MRI contrast agentGadoliniumCommunicationMagnetic PhenomenaRefrigerationchemistry.chemical_elementPentetic AcidInorganic ChemistryCold TemperatureMagnetizationchemistry.chemical_compoundHolmiumNuclear magnetic resonancechemistryCoordination ComplexesRefrigerationMagnetMagnetic refrigerationMagnetsPhysical and Theoretical ChemistryHolmiumDerivative (chemistry)Inorganic Chemistry
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Differentiation of benign and malignant lymph nodes in pediatric patients on ferumoxytol-enhanced PET/MRI.

2019

The composition of lymph nodes in pediatric patients is different from that in adults. Most notably, normal lymph nodes in children contain less macrophages. Therefore, previously described biodistributions of iron oxide nanoparticles in benign and malignant lymph nodes of adult patients may not apply to children. The purpose of our study was to evaluate if the iron supplement ferumoxytol improves the differentiation of benign and malignant lymph nodes in pediatric cancer patients on 18F-FDG PET/MRI. Methods: We conducted a prospective clinical trial from May 2015 to December 2018 to investigate the value of ferumoxytol nanoparticles for staging of children with cancer with 18F-FDG PET/MRI.…

Malemedicine.medical_specialtyAdolescentAnemiaMRI contrast agentMedicine (miscellaneous)030218 nuclear medicine & medical imagingLesioncancer imaging03 medical and health sciences0302 clinical medicineFluorodeoxyglucose F18lymph nodesNeoplasmsferumoxytolmedicineHumansProspective StudiesChildPharmacology Toxicology and Pharmaceutics (miscellaneous)Lymph nodeReceiver operating characteristicbusiness.industryCell Differentiationmedicine.diseasePediatric cancerMagnetic Resonance ImagingFerrosoferric Oxide3. Good healthFerumoxytolmedicine.anatomical_structurePET/MRI030220 oncology & carcinogenesisPositron-Emission TomographyNanoparticlesFemaleRadiologyLymphmedicine.symptomRadiopharmaceuticalsbusinessResearch PaperTheranostics
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