Search results for "Control systems"

Photoplethysmography imaging algorithm for continuous monitoring of regional anesthesia

2016

An efficient photoplethy smography imaging system and advanced algorithm for continuous monitoring of skin microcirculation was developed. The system comprises compact device and computer with software for visualizing of skin blood volume changes. The software is able to process high-resolution microcirculation amplitude maps in real-time. It was tested in clinical environment during the regional anesthesia procedures. The Eulerian-based method showed improved sensitivity and higher resolution of microcirculation maps.

Design and development of a fNIRS system prototype based on SiPM detectors

2014

Functional Near Infrared Spectroscopy (fNIRS) uses near infrared sources and detectors to measure changes in absorption due to neurovascular dynamics in response to brain activation. The use of Silicon Photomultipliers (SiPMs) in a fNIRS system has been estimated potentially able to increase the spatial resolution. Dedicated SiPM sensors have been designed and fabricated by using an optimized process. Electrical and optical characterizations are presented. The design and implementation of a portable fNIRS embedded system, hosting up to 64 IR-LED sources and 128 SiPM sensors, has been carried out. The system has been based on a scalable architecture whose elementary leaf is a flexible board …

Fallzahlplanung in referenzkontrollierten Diagnosestudien

2002

Purpose: A tutorial illustration of a flexible approach to determine the sample size in reference-controlled diagnostic trials. Materials and Methods: Assuming the usual setting of a new diagnostic method to be compared with a reference method, the emphasis is on the sensitivity of the new method in comparison with the reference method, using a binary outcome (positive versus negative) for both methods. Based on the confidence interval of the sensitivity, a simple but flexible procedure for determining the sample size is described, which incorporates clinically interpretable information. The procedure is illustrated by the fictious planning of a trial to assess the diagnostic value of MRI v…

Fast algorithm for detection of reference spheres in digital panoramic radiography.

2009

In this paper, an algorithm for detection of reference spheres from digital panoramic radiographic images is presented. The proposed algorithm was tested on a database of 107 digital panoramic radiographic images which were used for dental diagnostics. Results show that the proposed method exhibits for detection of reference spheres, a sensitivity of 97.33% and specificity of 93.85%. Performance time differed between 0.55 and 2.36s depending on image size. The aim of this work was to provide a fast ellipse detection algorithm to reduce measuring time on preoperative implant planning by lowering the computational cost.

Weighted nonlinear correlation for controlled discrimination capability

2002

We recently demonstrated the high discrimination capability as well as the high sensitivity to small intensity variations of the sliced orthogonal nonlinear generalized (SONG) correlation. This nonlinear correlation has a correlation matrix representation. Previous papers considered only the principal diagonal elements of the correlation matrix. We propose using the off-diagonal non-zero elements of the SONG correlation matrix in order to achieve variable discrimination performance and controlled detection adapted to the gray-scale variations. Moreover, we introduce negative coefficients in order to improve the discrimination properties of the SONG correlation. To control the degree of reco…

DETECTING TUBERCULIN SENSITIVITY

1982

KRAS-mutated intrahepatic cholangiocarcinoma shows preferential sensitivity towards PARP-1-based interventions

2020

Deep learning model deploying on embedded skin cancer diagnostic device

2020

The number of research papers, where neural networks are applied in medical image analysis is growing. There is a proof that Convolutional Neural Networks (CNN) are able to differentiate skin cancer from nevi with greater accuracy than experienced specialists on average (sensitivity 82% and 73% accordingly).1 Team's latest research2 allows achieving even greater accuracy, by using specific narrow-band illumination. Nevertheless, the overall probability of early skin cancer detection depends on the availability of diagnostic tools. If screening tools will be available to a high number of general practices, the chance of disease detection will increase. The previous research3 shows that scala…

A Multi-Objective Design Approach for the c Chart Considering Taguchi Loss Function

2013

The present paper proposes a multi-objective design approach for the c chart, considering in the optimization process of the chart parameters both the statistical and the economic objectives. In particular, the minimization of the hourly total quality related costs is the considered objective to carry out the economic goal, whereas the statistical objective is reached by the minimization the out-of-control average run length of the chart. A mixed integer non-linear constrained mathematical model is formulated to solve the treated multi-objective optimization problem, whereas the Pareto optimal frontier is described by the e-constraint method. In order to show the employment of the proposed …

Design of the Biotechnological System for the Cultivation of a Polysaccharide-Producing Microorganism and Metabolites Separation

1970

This paper presents a design of the biotechnological system established for the cultivation of a polysaccharide-producing microorganism and the separation of the polysaccharide together with other metabolites. The strain used is a halophilic archaeon called Haloferax mediterranei (Mironescu et al., 2003). On designing the biotechnological system, some requirements are important: The recipients and the pipes must be resistant to the corrosion action of the cultivation substrate very rich in NaCl (125 to 150 g/l); A command and control system for pH, temperature and substrate and inoculum feeding is necessary; A system for monitoring dissolved oxygen and gases evacuated from the bioreactor (O…