Search results for "Conventional"
showing 10 items of 361 documents
Summary and recommendations of the OARSI FDA osteoarthritis Assessment of Structural Change Working Group
2011
Import JabRef | WosArea Orthopedics; Rheumatology; International audience; Objective: The Osteoarthritis Research Society International initiated a number of working groups to address a call from the US Food and Drug Administration (FDA) on updating draft guidance on conduct of osteoarthritis (OA) clinical trials. The development of disease-modifying osteoarthritis drugs (DMOADs) remains challenging. The Assessment of Structural Change (ASC) Working Group aimed to provide a state-of-the-art critical update on imaging tools for OA clinical trials. Methods: The Group focussed on the performance metrics of conventional radiographs (CR) and magnetic resonance imaging (MRI), performing systemati…
An analytical model of heat transfer and fluid dynamic performances of an unconventional NTR engine for manned interplanetary missions
2009
Abstract An analytical model of fluid flow and heat transfer of a Nuclear Thermal Rocket (NTR) engine concept is presented. The engine is based on the direct conversion of the kinetic energy of the fission fragments (FFs) into the propellant enthalpy. The FFs can escape from an extremely thin layer of fissionable material: a sufficiently large surface coated with few micrometers of Americium 242m, confined by a neutron moderator–reflector, may become a critical reactor. Three dimensional coupled CFD-Monte Carlo simulations have already been presented in Di Piazza and Mulas (2006) . In this paper, an analytical integral 1-D model of fluid dynamics and heat transfer is built in order to fores…
Conventionalism and Law
1995
The defining property of those theories which are usually collected under the label “legal positivism” is the thesis that certain social facts form a sufficient condition for the existence of law and legal systems. The acceptance or rejection of this thesis has important consequences, but there are other issues in legal theory which are of equal importance. Thus, the positivism-antipositivism issue is only one possible way of classifying different theories.
Bonding to silicate ceramics : conventional technique compared with a simplified technique
2017
Background Silicate ceramic bonding is carried out by acid-etching with hydrofluoric acid (HF) followed by an application of silane. By replacing HF with ammonium polyfluoride, contained in the same flask as the silane, the number of steps in this clinical procedure, can be reduced, while maintaining bond strength values, and reducing toxicity. A shear bond test was performed to compare the conventional and the simplified surface treatment techniques. Material and methods Twenty ceramic samples were fabricated from IPS emax CAD® ceramic (Ivoclar Vivadent) and divided into two groups (G1 and G2) (n=10). The conventional technique was applied to G1 samples, and the simplified technique to G2 …
Long-term volume-targeted pressure-controlled ventilation: sense or nonsense?
2017
The technology underlying the development of novel ventilatory modes for long-term noninvasive ventilation of patients with chronic hypercapnia is continuously evolving. Volume-targeted pressure-controlled ventilation is a hybrid ventilation mode designed to combine the advantages of conventional ventilation modes, while avoiding their drawbacks. However, manufacturers have created different names and have patented algorithms and set-up variables, which can result in confusion for physicians and respiratory therapists. In addition, clear evidence for the superiority of this novel mode has not yet been established. These factors have most likely hindered more widespread use of this mode in c…
Estudio de perfilación de metabolitos secundarios de extractos vegetales obtenidos mediante técnicas y estrategias no convencionales para el desarrol…
2022
En esta tesis doctoral se desarrolló en el entorno de la economía verde y el reciclaje de residuos alimentarios estudiando diferentes técnicas de extracción no convencionales. En primer lugar, se aislaron polifenoles de matrices complejas producto del desperdicio de alimentos, como son las hojas de Moringa oleifera, mediante extracción asistida por ultrasonidos (UAE). El enfoque de diseño experimental permitió optimizar las mejores condiciones de extracción (MeOH:H2O 50:50, v/v, proporcion 1:60 Sólido/Líquido (S/L), 60°C, 60 min) para obtener un contenido fenólico total (TPC) de 13,4 mg expresados como equivalentes de ácido gálico (GAE)/g de materia seca. Por lo tanto, la caracterización y …
Sonographie bei Skelettmetastasen - Stellenwert im Vergleich zur Computertomographie und konventionellen Röntgendiagnostik
1990
The value of CT, conventional radiography and ultrasound was compared in 40 patients with 52 skeletal metastases. For superficial lesions, the combination of sonography and conventional radiography was equivalent to CT in showing the extent of bone destruction and soft tissue involvement. As expected sonography was unsatisfactory for deeper lesions. Sonography can provide useful information for planning radiation therapy for superficial lesions, but it does not replace conventional radiography.
Procedural characteristics and outcomes following chronic total occlusion coronary intervention: pooled analysis from 5 registries.
2021
Background Recent improvement in clinical skills, technology and hardware has resulted in improved success rates with chronic total occlusion (CTO) percutaneous coronary intervention (PCI). We performed a study level pooled analysis from the five largest registries of percutaneous coronary intervention (PCI) of CTO. Research design and methods We conducted pooled analysis of 9500 patients in registries and data on procedural characteristics, technical success, and MACCE was collected. Results A total of 9500 patients were included in the analysis. Mean age was 65.4 years with previous CABG in 24.8%, reattempt procedure in 24.8% and mean JCTO score was 2.2. Final wiring strategy in hybrid al…
Guideline-adherence and perspectives in the acute management of unstable angina - Initial results from the German chest pain unit registry.
2015
Abstract Background We investigated the current management of unstable angina pectoris (UAP) in certified chest pain units (CPUs) in Germany and focused on the European Society of Cardiology (ESC) guideline-adherence in the timing of invasive strategies or choice of conservative treatment options. More specifically, we analyzed differences in clinical outcome with respect to guideline-adherence. Method Prospective data from 1400 UAP patients were collected. Analyses of high-risk criteria with indication for invasive management and 3-month clinical outcome data were performed. Guideline-adherence was tested for a primarily conservative strategy as well as for percutaneous coronary interventi…
Small-diameter titanium Grade IV and titanium-zirconium implants in edentulous mandibles: three-year results from a double-blind, randomized controll…
2015
OBJECTIVE: The aim of this study was to compare crestal bone-level changes, soft tissue parameters and implant success and survival between small-diameter implants made of titanium/zirconium (TiZr) alloy or of Grade IV titanium (Ti) in edentulous mandibles restored with removable overdentures. MATERIALS AND METHODS: This was a randomized, controlled, double-blind, split-mouth multicenter clinical trial. Patients with edentulous mandibles received two Straumann bone-level implants (diameter 3.3 mm), one of Ti Grade IV (control) and one of TiZr (test), in the interforaminal region. Implants were loaded after 6-8 weeks and removable Locator-retained overdentures were placed within 2 weeks of l…