Search results for "Core"
showing 10 items of 1999 documents
Transversus abdominis and multifidus asymmetry in runners measured by MRI: a cross-sectional study
2019
ObjectiveThe transversus abdominis muscle (TrA) is active during running as a secondary respiratory muscle and acts, together with the multifidus, as trunk stabiliser. The purpose of this study was to determine size and symmetry of TrA and multifidus muscles at rest and with contraction in endurance runners without low back pain.DesignCross-sectional study.SettingA medical imaging centre in Melbourne, Australia.ParticipantsThirty middle-aged (43years±7) endurance-trained male (n=18) and female (n=12) runners without current or history of low back pain.Outcome measuresMRI at rest and with the core engaged. The TrA and multifidus muscles were measured for thickness and length (TrA) and antero…
The COVID-19 Assessment for Survival at Admission (CASA) Index: A 12 Months Observational Study
2021
Objective: Coronavirus disease 2019 (COVID-19) is a disease with a high rate of progression to critical illness. However, the stratification of patients at risk of mortality is not well defined. In this study, we aimed to define a mortality risk index to allocate patients to the appropriate intensity of care.Methods: This is a 12 months observational longitudinal study designed to develop and validate a pragmatic mortality risk score to stratify COVID-19 patients aged ≥18 years and admitted to hospital between March 2020 and March 2021. Main outcome was in-hospital mortality.Results: 244 patients were included in the study (mortality rate 29.9%). The Covid-19 Assessment for Survival at Admi…
Lopinavir/ritonavir and darunavir/cobicistat in hospitalized covid-19 patients: Findings from the multicenter italian corist study
2021
Background: Protease inhibitors have been considered as possible therapeutic agents for COVID-19 patients.Objectives: To describe the association between lopinavir/ritonavir (LPV/r) or darunavir/cobicistat (DRV/c) use and in-hospital mortality in COVID-19 patients.Study Design: Multicenter observational study of COVID-19 patients admitted in 33 Italian hospitals. Medications, preexisting conditions, clinical measures, and outcomes were extracted from medical records. Patients were retrospectively divided in three groups, according to use of LPV/r, DRV/c or none of them. Primary outcome in a time-to event analysis was death. We used Cox proportional-hazards models with inverse probability of…
Phase I dose-escalation single centre clinical trial to evaluate the safety of infusion of memory T cells as adoptive therapy in COVID-19 (RELEASE)
2021
Abstract Background Effective treatments are still needed to reduce the severity of symptoms, time of hospitalization, and mortality of COVID-19. SARS-CoV-2 specific memory T-lymphocytes obtained from convalescent donors recovered can be used as passive cell immunotherapy. Methods Between September and November 2020 a phase 1, dose-escalation, single centre clinical trial was conducted to evaluate the safety and feasibility of the infusion of CD45RA− memory T cells containing SARS-CoV-2 specific T cells as adoptive cell therapy against moderate/severe cases of COVID-19. Nine participants with pneumonia and/or lymphopenia and with at least one human leukocyte antigen (HLA) match with the don…
Corema album archaeobotanical remains in western Mediterranean basin. Assessing fruit consumption during Upper Palaeolithic in Cova de les Cendres (A…
2019
[EN] Information about plant gathering by Palaeolithic hunter-gatherers in Europe is scarce because of the problems of preservation of plant remains in archaeological sites and due to the lack of application of archaebotanical analysis in many of them. Botanical macroremains wood charcoal, seeds, fruits, leaves, etc. - provide information not only about palaeoeconomy of hunter-gatherers, but also about climate, landscape and vegetation dynamics. In Gravettian and Solutrean levels of Cova de les Cendres (Alicante, Spain), Corema album pyrenes (Empetraceae or crowberries family) have been identified. On the contrary, wood charcoal of this species has not been documented among the remains of f…
Impact of human activities on the central Mediterranean offshore: Evidence from Hg distribution in box-core sediments from the Ionian Sea
2008
The Palermo and Augusta urban/industrial areas (Sicily) are examples of contaminated coastal environments with a relatively high influx of unregulated industrial and domestic effluents. Three sediment box-cores were collected offshore of these urban/industrial areas in water depths of 60–150mduring two cruises (summers 2003/2004), dated by 210Pb and 137Cs, and analysed for total mercury concentration and total polycyclic aromatic hydrocarbon (PAH) concentration. Benthic foraminiferal assemblages were also examined (in terms of their distribution and morphology) to assess the potential use of benthic foraminifera as bioindicators of pollutant input and environmental change in these Mediterra…
Centennial- to millennial-scale climate oscillations in the Central-Eastern Mediterranean Sea between 20,000 and 70,000 years ago: Evidence from a hi…
2012
Abstract Here we present a high-resolution faunal, floral and geochemical (stable isotopes and trace elements) record from the sediments of Ocean Drilling Program Site 963 (central Mediterranean basin), which shows centennial/millennial-scale resemblance to the high-northern latitude rapid temperature fluctuations documented in the Greenland ice cores between 20 and 70 kyr BP. Oxygen and carbon isotopes, planktic foraminifera and calcareous nannofossil distributions suggest that Dansgaard–Oeschger (D/O) and Heinrich events (HE) are distinctly expressed in the Mediterranean climate record. Moreover, recurrent though subdued oscillations not previously identified in the Lateglacial Mediterran…
Chronological records of metal deposition in sediments from the Strait of Sicily, central Mediterranean: assessing natural fluxes and anthropogenic a…
2010
Abstract Sediment box-cores were recovered from the Strait of Sicily along two onshore–offshore transects in water depths of 29–500 m. Samples were dated by 210 Pb and analysed for major and trace elements. Inspections of chronological profiles integrated with application of statistical algorithms to the geochemical dataset and supported by in situ hydrological observations were used to assess factors driving element distributions. Mineralogical and chemical variability of sediments offshore of the southwestern Sicily coast reflect the irregular sea floor morphology of the Adventure Bank. Anthropogenic inputs explain enrichments with respect to background values for Sb, As, Pb, and Hg, that…
Saproxylic beetle assemblages of three managed oak woodlands in the Eastern Mediterranean
2008
Oak woodlands belong to the natural vegetation in most Mediterranean regions but have suffered from a long history of woodland devastation and overgrazing. The remaining woodlands have been managed in different ways, and we expected this to have effects on the fauna associated with trees. We investigated three different sites in the Eastern Mediterranean with flight-interception traps to analyse the impact of woodland management on dead wood and tree structures and the relevance for saproxylic beetle assemblages. Our results show significant differences in trunk diameter, stein density and dead wood diversity between the three sites. Old oaks in semi-open woodland are characterised by diver…
A high-resolution record of the last deglaciation in the Sicily Channel based on foraminifera and calcareous nannofossil quantitative distribution
2003
Abstract Relative abundance fluctuations in planktic foraminiferal and calcareous nannofossil assemblages are reported on the basis of a high-resolution study of ODP Leg 160 Hole 963D, drilled in the Sicily Strait, near Capo Rossello (southern Sicily). With its 8 m of undisturbed sediments, the core covers the interval from 1.5 to 23 kyr, allowing a 50–100-yr sampling resolution. All the short warm and cold events and sub-events recorded in this time interval in the GRIP Greenland ice core and at several Mediterranean sites were recognized. On this basis, a total number of nine ecozones based on planktic foraminifera and seven ecozones based on calcareous nannofossils were identified. A sho…