Search results for "Core"
showing 10 items of 1999 documents
Low-Latency Infrastructure-Based Cellular V2V Communications for Multi-Operator Environments With Regional Split
2021
Mobile network operators are interested in providing Vehicle-to-Vehicle (V2V) communication services using their cellular infrastructure. Regional split of operators is one possible approach to support multi-operator infrastructure-based cellular V2V communication. In this approach, a geographical area is divided into non-overlapping regions, each one served by a unique operator. Its main drawback is the communication interruption motivated by the inter-operator handover in border areas, which prevents the fulfillment of the maximum end-to-end (E2E) latency requirements of fifth generation (5G) V2V services related to autonomous driving. In this work, we enable a fast inter-operator handove…
Optimization of dual-core and microstructure fiber geometries for dispersion compensation and large mode area
2009
We investigate dual concentric core and microstructure fiber geometries for dispersion compensation. Dispersion values as large as -59 000 ps/(nm km) are achieved, over a broad wavelength range with full width at half maximum exceeding 100 nm. The trade-off between large dispersion and mode area is studied. Geometries with an effective mode area of 30 microm2 and dispersion -19 000 ps/(nm km) and 80 microm2 with -1600 ps/(nm km) are proposed.
El Balanced Scorecard y la reversión de las crisis de desempeño empresarial: una aplicación empírica en las empresas distribuidoras de electricidad d…
2015
Esta tesis doctoral valida la capacidad potencial del Balanced Scorecard, como sistema de gestión de las estrategias, para revertir las crisis de desempeño empresarial. La revisión del estado del arte de las investigaciones sobre: la estrategia empresarial, los sistemas de seguimiento al desempeño, así como del modelo de negocios; evidencia que la aplicación del BSC contribuye con el mejoramiento del desempeño estratégico de las organizaciones. A partir de estas consideraciones, se desarrolla un trabajo de investigación empírica en las empresas distribuidoras de electricidad de la República Dominicanas, dada la situación de crisis por la que han atravesado durante décadas, perdiendo miles d…
Flexible modeling for anatomically-based cardiac conduction system construction.
2010
We present a method to automatically deploy the peripheral section of the cardiac conduction system in ventricles. The method encodes anatomical information thorough rules that ensure that Purkinje network structures generated are realistic and comparable to those observed in ex-vivo studies. The core methodology is based in non-deterministic production rules that are parameterized by means of statistical functions. Input parameters allow the construction of a great diversity of Purkinje structures that could be incorporated in fine element ventricular models to perform electrophysiology simulations. Resulting Purkinje trees show good geometrical approximations of Purkinje core network and …
A laboratory comparison of Individual Targis/Vectris posts with standard fiberglass posts
2007
This article presents an in vitro analysis of a specific occlusal loading test on endodontically treated teeth restored with 2 different composite post materials. Individual, customized posts (IFPs) were compared to standard fiberglass posts (SFPs). The selected IFPs (standard cylindric Targis/Vectris posts) were compared to SFPs (Conic 6% Post, Ghimas). The posts were first subjected to a 3-point bending test to compare their flexural elastic properties. They were then used to restore 22 endodontically treated artificial maxillary central incisors and subjected to a specific occlusal loading simulation test. The loading test showed that IFP restorations performed better than SFP restoratio…
HBV core particles as a carrier for B cell/T cell epitopes.
2001
In the middle 80s, recombinant hepatitis B virus cores (HBc) gave onset to icosahedral virus-like particles (VLPs) as a basic class of non-infectious carriers of foreign immunological epitopes. The recombinant HBc particles were used to display immunodominant epitopes of hepatitis B, C, and E virus, human rhinovirus, papillomavirus, hantavirus, and influenza virus, human and simian immunodeficiency virus, bovine and feline leukemia virus, foot-and-mouth disease virus, murine cytomegalovirus and poliovirus, and other virus proteins, as well as of some bacterial and protozoan protein epitopes. Practical applicability of the HBc particles as carriers was enabled by their ability to high level …
A novel bio-orthogonal cross-linker for improved protein/protein interaction analysis
2015
International audience; The variety of protein cross-linkers developed in recent years illustrates the current requirement for efficient reagents optimized for mass spectrometry (MS) analysis. To date, the most widely used strategy relies on commercial cross-linkers that bear an isotopically labeled tag and N-hydroxysuccinimid-ester (NHS-ester) moieties. Moreover, an enrichment step using liquid chromatography is usually performed after enzymatic digestion of the cross-linked proteins. Unfortunately, this approach suffers from several limitations. First, it requires large amounts of proteins. Second, NHS-ester cross-linkers are poorly efficient because of their fast hydrolysis in water. Fin…
Evaluating protein structures determined by structural genomics consortia.
2006
Structural genomics projects are providing large quantities of new 3D structural data for proteins. To monitor the quality of these data, we have developed the protein structure validation software suite (PSVS), for assessment of protein structures generated by NMR or X-ray crystallographic methods. PSVS is broadly applicable for structure quality assessment in structural biology projects. The software integrates under a single interface analyses from several widely-used structure quality evaluation tools, including PROCHECK (Laskowski et al., J Appl Crystallog 1993;26:283-291), MolProbity (Lovell et al., Proteins 2003;50:437-450), Verify3D (Luthy et al., Nature 1992;356:83-85), ProsaII (Si…
Antigen processing influences HIV-specific cytotoxic T lymphocyte immunodominance
2016
Udgivelsesdato: 2009-May-03 Although cytotoxic T lymphocytes (CTLs) in people infected with human immunodeficiency virus type 1 can potentially target multiple virus epitopes, the same few are recognized repeatedly. We show here that CTL immunodominance in regions of the human immunodeficiency virus type 1 group-associated antigen proteins p17 and p24 correlated with epitope abundance, which was strongly influenced by proteasomal digestion profiles, affinity for the transporter protein TAP, and trimming mediated by the endoplasmatic reticulum aminopeptidase ERAAP, and was moderately influenced by HLA affinity. Structural and functional analyses demonstrated that proteasomal cleavage 'prefer…
Canonical azimuthal rotations and flanking residues constrain the orientation of transmembrane helices.
2013
AbstractIn biological membranes the alignment of embedded proteins provides crucial structural information. The transmembrane (TM) parts have well-defined secondary structures, in most cases α-helices and their orientation is given by a tilt angle and an azimuthal rotation angle around the main axis. The tilt angle is readily visualized and has been found to be functionally relevant. However, there exist no general concepts on the corresponding azimuthal rotation. Here, we show that TM helices prefer discrete rotation angles. They arise from a combination of intrinsic properties of the helix geometry plus the influence of the position and type of flanking residues at both ends of the hydrop…