Search results for "Core"

Pārejas metālu halkogenīdu 1D un 2D nanostruktūru sintēze un raksturošana

2016

Darbā tiek aplūkotas divdimensiju (2D) pārejas metālu halkogenīdu - volframa un molibdēna disulfīdu - īpašības un iegūšanas metodes. Ir demonstrēta šo 2D mikrokristālu sintēzes metode no gāzveida reaģentiem, kā arī izstrādātas jaunas metodes viendimensiju (1D) metālu oksīdu nanovadu core-shell heterostruktūru izgatavošanai, veidojot plānus disulfīdu pārklājumus uz ZnO nanovadiem, izmantojot ar reaktīvo magnetrona izputināšanu iegūtu pārklājuma sulfurēšanu vai attiecīgo pārejas metālu amonija sāļu pārklājuma termolīzi gāzveida sēra klātbūtnē. Iegūtās nanostruktūras tika izgatavotas un raksturotas, izmantojot LU CFI pieejamās zinātniskās iekārtas. Darbs sastāv no literatūras apskata un eksper…

Sediment quality of the ecoregion Engure, Gulf of Riga, assessed by using ecotoxicity tests and biomarker responses

2014

Pētījuma mērķis bija novērtēt Engures ekoreģiona (Rīgas līča rietumu piekrastes) sedimentu kvalitāti, izmantojot sedimentu ekotoksicitātes testus. Lai noteiktu bioloģiskās atbildes reakcijas uz dažāda veida stresoriem, kā testorganismi pielietotas sānpeldes Monoporeia affinis and Pontogammarus robustoides, un izvēlēti biomarķieri (AChE, GST, GR, CAT, MT), kas noteikti gliemenēs Macoma balthica. Engures ekoreģionu varētu uzskatīt par nepiesārņotu rajonu, jo tā sedimentus raksturo salīdzinoši zemas smago metālu koncentrācijas. Engures ekoreģiona sedimentu ekotoksicitātes testu rezultāti neuzrādīja statistiski būtisku (>20% mirstība) toksisko efektu. Testorganismu izdzīvotība bija robežās no 8…

Overvåking av vitale parametere i sykehus : En sammenligning av manuelle og elektroniske overvåkingssystemer

2018

Masteroppgave i helse- og sosialinformatikk HSI500 - Universitetet i Agder 2018 Adverse events can be avoided by timely recognition of derangements in vital signs. Sørlandet Hospital HF (SSHF) has implemented an Early Warning Score System named "TILT"; 2Early identification of life-threatening conditions”. In 2017 SSHF started a project that tested wireless sensors for continuous monitoring of vital signs on wards. Patients were monitored by sensors and vital signs were also measured by traditional means during the project period. The aim of this study was to examine compliance with the vital signs monitoring protocol, and to examine the benefits of an electronic system. The following quest…

Meccanismi antitumorali degli oli essenziali estratti da piante succulente in un modello di leucemia mielocitica acuta multifarmacoresistente

Survival Risk Scores for Real-Life Relapsed/Refractory Multiple Myeloma Patients Receiving Elotuzumab or Carfilzomib In Combination With Lenalidomide…

2022

The present study aimed to develop two survival risk scores (RS) for overall survival (OS, SRSKRd/EloRd) and progression-free survival (PFS, PRSKRd/EloRd) in 919 relapsed/refractory multiple myeloma (RRMM) patients who received carfilzomib, lenalidomide, and dexamethasone (KRd)/elotuzumab, lenalidomide, and dexamethasone (EloRd). The median OS was 35.4 months, with no significant difference between the KRd arm versus the EloRd arm. In the multivariate analysis, advanced ISS (HR = 1.31; P = 0.025), interval diagnosis–therapy (HR = 1.46; P = 0.001), number of previous lines of therapies (HR = 1.96; P < 0.0001), older age (HR = 1.72; P < 0.0001), and prior lenalidomide exposure (…

Cementless total hip replacement with subtrochanteric femoral shortening for severe developmental dysplasia of the hip.

2003

Total joint replacement in patients suffering from developmental dysplasia of the hip poses specific technical difficulties due to insufficient bone stock at the site of the original and secondary acetabulum and a narrow, cranially displaced proximal femur. Twelve hips with severe congenital dislocation (4 Crowe type II, 5 type III, 3 type IV) were treated with cementless, porous structured total hip replacement. The cup was implanted at the anatomic height, a femoral segment was resected below the minor trochanter to reduce the femoral component in all cases. One femoral component was exchanged for a longer stem after 2 months due to insufficient fit and fill. After a mean follow-up of 5.1…

Primary total hip arthroplasty with fourth-generation ceramic bearings: Clinical and survival results with a minimum follow-up of 5 years.

2019

Abstract Objective To evaluate the clinical results and survival of primary hip prosthesis with ceramic delta bearings (C-C) with a minimum follow-up of 5 years. Material and method A total of 205 primary hip arthroplasties performed between 2008 and 2012 were studied. The clinical results, pre-surgical and at 5 years of follow-up were evaluated using the Harris Hip Score (HHS), the Short Form-36 (SF-36), the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), and the visual analogue scale (VAS). The position of the prosthetic components, periprosthetic osteolysis, loosening of the prosthetic components and ruptures of the ceramic components were studied radiologically. …

Nonadherence in outpatient thrombosis prophylaxis with low molecular weight heparins after major orthopaedic surgery

2010

Background: According to some current guidelines, extended thromboprophylaxis after hip and knee arthroplasties is recommended. Outpatient prophylaxis with low molecular weight heparins (LMWH) is an important part of this prophylaxis, although the rates of adherence to these regimens is not known. Questions/purposes: We determined (1) the degree of nonadherence (NA) of patients with LMWH outpatient prophylaxis, and (2) whether specific independent factors explain NA. Methods: NA was determined by syringe count and by indirect and direct questions to patients. We defined six different NA indicators. To identify factors explaining LMWH NA, we used three different logistic regression models. R…

A real life comparison of the effectiveness of adalimumab and golimumab in moderate-to-severe ulcerative colitis, supported by propensity score analy…

2018

Abstract Background Adalimumab and golimumab are effective in the treatment of moderate to severe ulcerative colitis. Aims We reported the comparative effectiveness of adalimumab and golimumab in ulcerative colitis. Methods 118 patients treated with adalimumab and 79 treated with golimumab were included and evaluated at 8 weeks and at the end of follow up. Results Overall clinical benefit was 72.6% at 8 weeks and 58.9% at the end of follow up. Patients with longer disease duration and those treated with adalimumab had a better outcome. Clinical benefit was 78.8% in adalimumab patients and 63.3% in golimumab patients (p = 0.026) after 8 weeks; it was 66.9% in adalimumab patients and 46.8% in…

Association between Serum Osteoprotegerin Levels and Severity of Coronary Artery Disease in Patients with Acute Myocardial Infarction

2021

International audience; Background. Osteoprotegerin (OPG), a glycoprotein of the tumour necrosis factor (TNF) superfamily, is one of the main biomarkers for vascular calcification. Aim. We aimed to evaluate the association between serum OPG levels and extent of coronary lesions in patients with acute myocardial infarction (MI). Methods. Consecutive patients hospitalized for an acute MI who underwent coronary angiography were included. SYNTAX score was calculated to assess the severity of coronary artery disease. The population was analysed in low (5 (3–6)), medium (11 (9–13)) and high (20 (18–23)) tertiles of SYNTAX score. Results. Among the 378 patients included, there was a gradual increa…