Search results for "Cornea"

Production of a Double-Layer Scaffold for the “On-Demand” Release of Fibroblast-like Limbal Stem Cells

2019

The production and characterization of a double layer scaffold, to be used as a system for the “on demand” release of corneal limbal stem cells are here reported. The devices used in the clinics and proposed so far in the scientific literature, for the release of corneal stem cells in the treatment of limbal stem cell deficiency, cannot control the in vivo space-time release of cells since the biomaterial of which they are composed is devoid of stimuli responsiveness features. Our approach was to produce a scaffold composed of two different polymeric layers that give the device the appropriate mechanical properties to be placed on the ocular surface and the possibility of releasing the stem…

Valutazione degli effetti antiossidanti del Resolvis OmegaTM in un modello di disfunzione corneale in vitro.

2015

EPA (acido eicosapentaenoico) e DHA (acido decosaesaeoico) sono derivati metabolici degli AGE (acidi grassi essenziali) e in particolare dell'acido linolenico (omega-3)

Ocular Drug Delivery Systems per la veicolazione di molecole bioattive al segmento posteriore dell'occhio

POLYSACCHARIDE-POLYAMINOACID HYDROGEL FILMS FOR POTENTIAL CORNEAL CELL RELEASE

2009

A hyaluronic acid derivative as a coating film for an electrospun cell releasing system in the treatment of corneal wounds

2017

The transparency of the cornea is maintained by the stem cells of the corneal epithelium in the limbal region; damage to the limbus may cause partial or total limbal stem cell deficiency that, may lead to blindness. The transplantation of cells is crucial to regenerate the damaged areas. The techniques currently employed consist in cadaveric corneal transplantation or in the use of amniotic membrane as a carrier for delivering cultured limbal stem cells to the cornea. Both these approaches show severe drawbacks such as the potential reject of the transplanted cornea and the risk of viral disease transmissions. Here we report the production of an electrospun device that could be exploited as…

Super-resolution-based magnification of endothelium cells from biomicroscope videos of the cornea

2018

We present a practical, robust, and effective pipeline to compute a high-resolution (HR) image of the corneal endothelium starting from a low-resolution (LR) video sequence obtained with a general purpose slit lamp biomicroscope. An image quality typical of dedicated and more expensive confocal microscopes is achieved via software magnification by exploiting information redundancy in the video sequence. In particular, the HR image is generated from the best LR frames, obtained by identifying the most suitable endothelium video subsequence using a support vector machine-based learning approach, followed by a robust graph-based frame registration. Results on long, real sequences show that the…

Acromegalia: aspetti clinici oftalmologici

2007

E' stata trattata l'acromegalia dal punto di vista oftalmologico con le sue sequele precoci e tardive.

Indicaxanthin from Opuntia Ficus Indica exerts antioxidant and anti-inflammatory effects in an in vitro model of human corneal dysfunction.

2014

Cheratiti batteriche

2012

Central Corneal Thickness in patients with acromegaly

2011

Introduction Acromegaly is hormonal disorder caused by excessive growth hormone (GH) by the pituitary gland, this results in anatomical changes in many organs and also in the eye and specially in cornea. Objective To perform a connection between the disease activity and the corneal changes Matériels et Méthodes In 28 patients with acromegaly and in 22 voluntary healthy the central corneal thickness (CCT) was measured by pachymeter. And the patients were divided in 2 groups: the first (“group A”) contains 13 cases with not controlled acromegaly; and the other one (“group B”) is related to 15 patients with controlled acromegaly Résultats Patients with acromegaly have a central corneal thickne…