Search results for "Coronavirus disease 2019"
showing 10 items of 953 documents
Age- and Sex-Graded Data Evaluation of Vaccination Reactions after Initial Injection of the BNT162b2 mRNA Vaccine in a Local Vaccination Center in Ge…
2021
A high vaccination rate of older and particularly chronically ill people against coronavirus disease-2019 (COVID-19) is likely one of the most important factors in containing the pandemic. When Germany’s vaccination campaign started on December 2020, vaccination prioritization was initially carried out starting with older population groups. Side effect rates in 1065 individuals who had received the first dose of the messenger ribonucleic acid (mRNA) vaccine BNT162b2 Tozinameran from BioNTech/Pfizer three weeks earlier were examined retrospectively. An age- and gender-graded data analysis showed clear age and gender differences with regard to vaccine-related adverse effects. In 77% of all in…
mRNA COVID-19 vaccines do not increase the short-term risk of clinical relapses in multiple sclerosis
2021
Multiple sclerosis (MS) is a chronic, immune-mediated disorder of the central nervous system. A novel coronavirus, namely SARS-CoV-2, has been recently responsible for the highly infectious disease referred as COVID-19, rapidly spreading all over the world. Many vaccines have been developed to control COVID-19 pandemic, including the mRNA vaccines Pfizer/BioNTech (BNT162b2) and Moderna (mRNA1273).1 The vaccination of people with MS (pwMS) has been recommended by several national and international MS societies. However, effectiveness and safety of anti-COVID-19 mRNA vaccines in MS need to be confirmed. The aim of this study was to evaluate the short-term risk of clinical relapses in pwMS in …
A new exciting hypothesis: direct correlation between periodontitis and clinical evolution of COVID-19 patients.
2020
The aim of the present opinion article is to hypothesize a possible correlation between clinical evolution of COVID-19 and a chronic inflammatory disease such as periodontitis. Reviews have been performed about the correlations between COVID-19 and IL-6, COVID-19 and diabetes, diabetes and periodontitis. Several studies discussed the role played by IL-6 in the pathogenetic mechanisms of COVID-19. A recent study found that COVID-19 adult patients with diabetes, without other comorbidities, were at greater risk of numerous diseases COVID related, such as severe pneumonia and excessive uncontrolled inflammatory responses. Besides, serum levels of inflammation-related biomarkers, such as IL-6, …
Cardiovascular and Cardioprotective Agents in 2021
2021
Le pharmacien et le consentement éclairé
2021
During the implementation of the Covid-19 vaccination, the issue of consent was widely commented upon. Many confusions arose between the withdrawal period, the obligation to collect written consent and many other more or less fanciful concepts. Informed consent is one of the founding stones of health democracy. It deserves to be understood in order to be intelligently applied.
Vaccin contre la Covid-19, une course contre le temps
2021
Diabetes and COVID-19: A Tale of 2 Pandemics.
2021
Abstract: Epidemiological studies indicate that diabetes is the second most common comorbidity in COVID-19 (coronavirus disease 2019). Dapagliflozin, a sodium-glucose co-transporter 2 inhibitor, exerts direct cardioprotective and nephroprotective effects. DARE-19 (Dapagliflozin in Respiratory Failure in Patients With COVID-19), an ongoing clinical trial, is designed to investigate the impact of dapagliflozin on COVID-19 progression. This article discusses the potential favorable impact of dapagliflozin on COVID-19 and its complications.
The Post-Lockdown Era: What Is Next in Italy?
2020
The current outbreak of the COVID-19 infection, which started in December 2019 in Wuhan (China), was declared a pandemic by the World Health Organization (WHO) on the 11th of March, 2020.
Editorial: The Challenge of New Therapeutic Approaches for Unmet Therapeutic Needs
2020
Multiscale three-dimensional imaging of intact human organs down to the cellular scale using hierarchical phase-contrast tomography
2021
ABSTRACTHuman organs are complex, three-dimensional and multiscale systems. Spatially mapping the human body down through its hierarchy, from entire organs to their individual functional units and specialised cells, is a major obstacle to fully understanding health and disease. To meet this challenge, we developed hierarchical phase-contrast tomography (HiP-CT), an X-ray phase propagation technique utilising the European Synchrotron Radiation Facility’s Extremely Brilliant Source: the world’s first high-energy 4th generation X-ray source. HiP-CT enabled three-dimensional and non-destructive imaging at near-micron resolution in soft tissues at one hundred thousand times the voxel size whilst…