Search results for "Correction"

SEOM clinical guideline for treatment of kidney cancer (2017)

2017

Abstract The goal of this article is to provide recommendations about the management of kidney cancer. Based on pathologic and molecular features, several kidney cancer variants were described. Nephron-sparing techniques are the gold standard of localized disease. After a randomized trial, sunitinib could be considered in adjuvant treatment in high-risk patients. Patients with advanced disease constitute a heterogeneous population. Prognostic classification should be considered. Both sunitinib and pazopanib are the standard options for first-line systemic therapy in advanced renal cell carcinoma. Based on the results of two randomized trials, both nivolumab and cabozantinib should be consid…

Correction to: Assessment of intratumor immune-microenvironment in colorectal cancers with extranodal extension of nodal metastases

2019

No data is available on the molecular background of the extra-nodal extension (ENE) of lymph node metastasis (LN) in colorectal cancer (CRC).A series of 22 ENE-positive CRCs was considered and three samples per case were selected (the primary CRC, an ENE-negative and an ENE-positive metastatic LN). Samples (n = 66) were analysed by immunohistochemistry for PD-L1, CD4, CD8, CD68 and CD80. Fifteen out of twenty-two cases were further profiled through a hotspot multigene mutational custom panel, including 164 hotspot regions ofA significantly higher percentage of CD4-, CD8- and CD68-positive cells was observed at the invasive front of both CRCs and in ENE in contrast with what observed at the …

Correction:Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrom…

2020

Lynch syndrome (LS) results from pathogenic variants in the mismatch repair (MMR) genes and is the most common hereditary cancer syndrome, affecting an estimated 1 in 300 individuals. Pathogenic variants in each of the MMR genes path_MLH1, path_MSH2, path_MSH6, and path_PMS2 result in different risks for cancers in organs including the colorectum, endometrium, ovaries, stomach, small bowel, bile duct, pancreas, and upper urinary tract. Accurate estimates of these risks are essential for planning appropriate approaches to the prevention or early diagnosis of cancers but the robustness of previous studies has been limited by factors including retrospective design,1,2 lack of validation in ind…

Supervised Physical Training Enhances Muscle Strength but Not Muscle Mass in Prostate Cancer Patients Undergoing Androgen Deprivation Therapy: A Syst…

2019

Introduction: Androgen deprivation therapy (ADT) is considered the basic treatment for advanced prostate cancer, but it is highly associated with detrimental changes in muscle mass and muscle strength. The aim of this meta-analysis was to investigate the effects of supervised physical training on lean mass and muscle strength in prostate cancer patients undergoing ADT. Methods: A systematic literature search was performed using MEDLINE, Embase, and ScienceDirect until October 2018. Only studies that examined both muscle mass and strength in prostate cancer patients undergoing ADT were included. Outcomes of interest were changes in lean body mass (surrogate for muscle mass) as well as upper …

Improved Method for Orbital Elements Differential Correction.

1990

As was pointed out by IAU in 1976, an important problem in fundamental astronomy is the improvement of the vernal equinox and equator positions. To this aim, it is necessary to know the accurate values of minor planets orbital elements. The classical methods of orbital elements differential corrections are based on linking the observations at different epochs considering equal derivatives respect to the initial and osculating elements. In this paper we present an improved method in which the least squares matrix coefficients is calculated from the integration of the Lagrange planetary equations and its derivatives.

Mechanical properties of provisional dental materials: A systematic review and meta-analysis

2018

Provisional restorations represent an important phase during the rehabilitation process, knowledge of the mechanical properties of the available materials allows us to predict their clinical performance. At present, there is no systematic review, which supports the clinicians' criteria, in the selection of a specific material over another for a particular clinical situation. The purpose of this systematic review and meta-analysis was to assess and compare the mechanical properties of dimethacrylates and monomethacrylates used in fabricating direct provisional restorations, in terms of flexural strength, fracture toughness and hardness. This review followed the PRISMA guidelines. The searche…

Hallux Valgus Correction in Young Patients with Minimally Invasive Technique

2012

The term hallux valgus was introduced into the literature in 1871 when Hueter (Hueter, 1871, as cited in Kelikian, 1965) defined the deformity as an abduction contracture in which the great toe is turned away from the mid-line of the body(fig. 1). The adjective valgus implies a static deformity and should not be used interchangeably with abductus which refers to movement caused by muscle function.

Non-surgical correction of gummy smile using temporary skeletal mini-screw anchorage devices : a systematic review

2021

Background There are no studies that have systematically reviewed randomized control trials and/or prospective cohort studies that have assessed the significance of temporary skeletal mini-screw anchorage devices (TSAD) for the correction of gummy-smile. The aim of the present systematic review was to assess the significance of non-surgical correction of gummy smile using TSAD. Material and methods The addressed focused question was "Are temporary skeletal mini-screw anchorage devices effective for the correction of gummy smile?" Indexed databases were searched up to and including May 2020. Different combinations of the following key-indexing terms were used: anchorage; gummy smile, mini-sc…

Reply: “The Impact of 68Ga-PSMA PET/CT and PET/MRI on the Management of Prostate Cancer”

2019

VBFNLO: A parton level Monte Carlo for processes with electroweak bosons

2009

VBFNLO is a fully flexible parton level Monte Carlo program for the simulation of vector boson fusion, double and triple vector boson production in hadronic collisions at next-to-leading order in the strong Coupling constant. VBFNLO includes Higgs and vector boson decays with full spin correlations and all off-shell effects. In addition, VBFNLO implements CP-even and CP-odd Higgs boson via gluon fusion, associated with two jets, at the leading-order one-loop level with the full top- and bottom-quark mass dependence in a generic two-Higgs-doublet model. A variety of effects arising from beyond the Standard Model physics are implemented for selected processes. This includes anomalous coupling…