Search results for "Cortex"

Blocking NMDA-receptors in the pigeon's "prefrontal" caudal nidopallium impairs appetitive extinction learning in a sign-tracking paradigm

2015

Extinction learning provides the ability to flexibly adapt to new contingencies by learning to inhibit previously acquired associations in a context-dependent manner. The neural networks underlying extinction learning were mostly studied in rodents using fear extinction paradigms. To uncover invariant properties of the neural basis of extinction learning, we employ pigeons as a model system. Since the prefrontal cortex of mammals is a key structure for extinction learning, we assessed the role of N-methyl-D-aspartate receptors (NMDARs) in the nidopallium caudolaterale, the avian functional equivalent of mammalian prefrontal cortex. Since NMDARs in prefrontal cortex have been shown to be rel…

Chronic Distress in Male Mice Impairs Motivation Compromising Both Effort and Reward Processing With Altered Anterior Insular Cortex and Basolateral …

2021

AbstractIn humans and mammals, effort-based decision-making for monetary or food rewards paradigms contribute to the study of adaptive goal-directed behaviours acquired through reinforcement learning. Chronic distress modelled by repeated exposure to glucocorticoids in rodents induces suboptimal decision-making under uncertainty by impinging on instrumental acquisition and prompting negative valence behaviours. In order to further disentangle the motivational tenets of adaptive decision-making, this study addressed the consequences of enduring distress on relevant effort and reward processing dimensions. Experimentally, appetitive and consummatory components of motivation were evaluated in …

How functional coupling between the auditory cortex and the amygdala induces musical emotion: a single case study.

2013

Music is a sound structure of remarkable acoustical and temporal complexity. Although it cannot denote specific meaning, it is one of the most potent and universal stimuli for inducing mood. How the auditory and limbic systems interact, and whether this interaction is lateralized when feeling emotions related to music, remains unclear. We studied the functional correlation between the auditory cortex (AC) and amygdala (AMY) through intracerebral recordings from both hemispheres in a single patient while she listened attentively to musical excerpts, which we compared to passive listening of a sequence of pure tones. While the left primary and secondary auditory cortices (PAC and SAC) showed …

The Interaction of Person-Affect-Cognition-Execution (I-PACE) model for addictive behaviors: Update, generalization to addictive behaviors beyond int…

2019

We propose an updated version of the Interaction of Person-Affect-Cognition-Execution (I-PACE) model, which we argue to be valid for several types of addictive behaviors, such as gambling, gaming, buying-shopping, and compulsive sexual behavior disorders. Based on recent empirical findings and theoretical considerations, we argue that addictive behaviors develop as a consequence of the interactions between predisposing variables, affective and cognitive responses to specific stimuli, and executive functions, such as inhibitory control and decision-making. In the process of addictive behaviors, the associations between cue-reactivity/craving and diminished inhibitory control contribute to th…

Musical training facilitates the neural discrimination of major versus minor chords in 13-year-old children

2012

Music practice since childhood affects the development of hearing skills. An important classification in Western music is the chords’ major-minor dichotomy. Its preattentive auditory discrimination was studied here using a mismatch negativity (MMN) paradigm in 13-year-olds with active hobbies, music-related (music group) or other (control group). In a context of root major chords, root minor chords and inverted major chords were presented infrequently. The interval structure of inverted majors differs more from root majors than the interval structure of root minors. However, the identity of the chords is the same in inverted and root majors (major), but different in root minors. The deviant…

2021

Abstract Pantomime has a long tradition in clinical neuropsychology of apraxia. It has been much more used by researchers and clinicians to assess tool-use disorders than real tool use. Nevertheless, it remains incompletely understood and has given rise to controversies, such as the involvement of the left inferior parietal lobe or the nature of the underlying cognitive processes. The present article offers a comprehensive framework, with the aim of specifying the neural and cognitive bases of pantomime. To do so, we conducted a series of meta-analyses of brain-lesion, neuroimaging, and behavioral studies about pantomime and other related tasks (i.e., real tool use, imitation of meaningless…

The Prefrontal Cortex and Neurological Impairments of Active Thought

2018

This article reviews the effects of lesions to the frontal cortex on the ability to carry out active thought, namely, to reason, think flexibly, produce strategies, and formulate and realize plans. We discuss how and why relevant neuropsychological studies should be carried out. The relationships between active thought and both intelligence and language are considered. The following basic processes necessary for effective active thought are reviewed: concentration, set switching, inhibiting potentiated responses, and monitoring and checking. Different forms of active thought are then addressed: abstraction, deduction, reasoning in well-structured and ill-structured problem spaces, novel st…

The Argument Dependency Model

2015

This chapter summarizes the architecture of the extended Argument Dependency Model (eADM), a model of language comprehension that aspires toward neurobiological plausibility. It combines design principles from neurobiology with insights on cross-linguistic diversity. Like other current models, the eADM posits that auditory language processing proceeds along two distinct streams in the brain emanating from auditory cortex: the antero-ventral and postero-dorsal streams. Both streams are organized hierarchically and information processing takes place in a cascaded fashion. Each stream has functionally unified computational properties congruent with its role in primate audition. While the dorsa…

Lesion of areas 17/18/19: effects on the cat's performance in a binary detection task

1988

The ability of two cats to discriminate between two geometrical outline patterns in the presence of superimposed Gaussian visual noise — i.e. in a binary detection task — was tested before and after bilateral removal of cortical areas 17, 18 and 19. The detection probability PD was measured as a function of the signal-to-noise ratio. After a lesion of areas 17, 18 and 19 both cats were unable to carry out the discrimination tasks. Their detection performance dropped to chance level, but after an extensive phase of retraining (3 months) they regained the ability to discriminate visual patterns. It was thus possible to obtain detection curves and to determine a measure of a performance which …

Different World Views

2010

When we study communication systems in other animal species, we are led to the conclusion that extraterrestrial intelligent beings are likely to have systems of communication similar to the human one in at least some aspects. That is to say, communication is accomplished by means of the combination of certain information elements playing a role analogous to words, or that the system is a symbolic language (or even both things simultaneously). But in communication, it is also very important how information is transmitted (pictorially, by means of ideograms, letters, etc.), which is going to be strongly determined by the species’specific perception of the world.