Search results for "Cost-benefit analysi"
showing 10 items of 148 documents
Low intensity vs. self-guided Internet-delivered psychotherapy for major depression: A multicenter, controlled, randomized study
2013
Abstract Background Major depression will become the second most important cause of disability in 2020. Computerized cognitive-behaviour therapy could be an efficacious and cost-effective option for its treatment. No studies on cost-effectiveness of low intensity vs self-guided psychotherapy has been carried out. The aim of this study is to assess the efficacy of low intensity vs self-guided psychotherapy for major depression in the Spanish health system. Methods The study is made up of 3 phases: 1.- Development of a computerized cognitive-behaviour therapy for depression tailored to Spanish health system. 2.- Multicenter controlled, randomized study: A sample (N=450 patients) with mild/mod…
Optimizing the Personalized, Risk-Adjusted Management of Pulmonary Embolism: An Integrated Clinical Trial Programme
2018
Acute pulmonary embolism (PE) contributes significantly to the global burden of cardiovascular disease. The severity of the acute PE event determines the expected estimated risk of early death. This risk is influenced by the degree of dysfunction of the right ventricle (RV), as assessed by the presence of acute RV pressure overload on imaging and/or elevated cardiac biomarkers, and by demographic and clinical factors, including relevant comorbidities. Haemodynamic instability and cardiogenic shock is at the top of the PE severity spectrum, as it represents the most extreme manifestation of RV failure and a key determinant of poor prognosis. Ideally, risk-adjusted treatment should implement:…
Assessment of wastewater treatment plant design for small communities: Environmental and economic aspects
2012
The preliminary design and economic assessment of small wastewater treatment plants (less than 2000 population equivalent) are issues of particular interest since wastewaters from most of these agglomerations are not covered yet. This work aims to assess nine different technologies set-up for the secondary treatment in such type of facilities embracing both economic and environmental parameters. The main novelty of this work is the combination of an innovative environmental decision support system (EDSS) with a pioneer approach based on the inclusion of the environmental benefits derived from wastewater treatment. The integration of methodologies based on cost-benefit analysis tools with th…
Evaluating Infrastructure Alternatives for Regional Water Supply Systems by Model-assisted Cost-benefit Analysis – A Case Study from Apulia, Italy
2014
The main challenge associated to regional water supply systems planning lies in understanding the best infrastructure alternatives to improve service given a certain configuration of the resources system. While cost-effectiveness assessments are still widespread in this type of analyses, they do not account for the fact that, especially in mature systems, service improvements tend to follow the law of marginal diminishing returns, so that a cost – benefit assessment should be preferable. Both costs and benefits can be organized into a cost-benefit analysis (CBA) framework. In a complex system, a model reproducing its topology and characteristics better describes the impacts of the alternati…
Social return on investment (SROI), including elements on cost-benefit Analysis
2017
The chapter deals with the theme of social return on investments (SROI), including general elements of cost–benefit analysis (CBA). In addition, some major appraisal tools for public projects are discussed. SROI is a method that aims to measure social outputs, and value of social outcomes in monetary terms (Boyd, 2004). The basic assump- tion underlying the SROI technique is that all economic organizations (whether private or public) have an impact on people, society and the environment. Thus, the technique is always underpinned by an underlying model or conception of society. Such an impact can be strictly economic, social, and/or environmental, respectively. By economic we mean all that h…
The Hip Fracture Surgery in Elderly Patients (HIPELD) study: protocol for a randomized, multicenter controlled trial evaluating the effect of xenon o…
2012
Trials 13, 180 (2012). doi:10.1186/1745-6215-13-180
Starpfunkcionālu komandu veidošana biznesa organizācijās
2019
Šajā pētījumā galvenā uzmanība pievērsta savstarpēji funkcionējošu komandu izveidošanai mazos uzņēmumos un to analīzei, izmantojot izmaksu un ieguvumu analīzi. Turklāt pētījums ir arī vērsts uz problēmu noteikšanu sākotnējā posmā. Caur pētījumiem un precīzu datu analīzi bija noskaidrota nepieciešamība starpfunkcionālu komanu veidošanai. Pamatojoties uz pierādījumiem, kuri ir sniegti pēc visu pētījumu procedūru pabeigšanas, uzņēmums var pieņemt lēmumu. Šī pētījuma rezultāti atklāj vairākus faktorus, kas būtiski ietekmēja darbiniekus, kuri strādā dažādās struktūrvienībās: spēju efektīvi sazināties un dibināt ciešas attiecības ar citiem, lai sasniegtu kopējo mērķi. Pirmajā nodaļā ir aplūkota s…
Economic assessment of sicilian loquat orchards
2015
The majority of Italian production of loquat (Eriobotrya japonica) derives from the Palermo province, along the northern Sicilian coast. However, this area is characterized by family orchards, traditional cultural techniques, and inadequate commercial organization. These appear to affect negatively the production costs and reduce the farmersâ income, decreasing the competitiveness of Sicilian loquat orchards. This study evaluates the economic viability of Sicilian loquat orchards by means of cost-benefit analysis (CBA). In particular, for the investment assessment some financial indicators have been calculated such as net present value (NPV), discounted payback time (DPBT), and internal r…
Topical Fluoride for Preventing Dental Caries in Children and Adolescents
2012
The use of topically applied fluoride has been widely researched as a means to reduce the risk of dental caries in conjunction with other treatment modalities (mechanical oral hygiene, dietary control, antimicrobial intervention, pit and fissure sealants). There is overwhelming evidence that reports not only the significance and importance of the use of fluoride as a caries-preventive agent, but also how safe fluoride application is when used appropriately, particularly in higher risk individuals and populations. This paper reviews the caries-protective benefits of topical fluoride application in children and adolescents, with an emphasis on the clinical efficacy and safety of the vehicles …
Financial Aspects of Cervical Disc Arthroplasty: A Narrative Review of Recent Literature
2020
Recently, there has been significant interest in understanding the cost-effectiveness of treatments in spine surgery as health care systems in the United States move toward value-based care and alternative payment models. Previous studies have shown comparable outcomes of cervical disc arthroplasty (CDA) and anterior cervical discectomy fusion; however, there is a lack of consensus on the cost-effectiveness of CDA to support full adoption. Evidence of the limitations of these cost-analysis studies also exists in the literature, including industry funding, potential selection bias, and varying methods of calculating value. The goal of this narrative review is to provide an overview of the co…