Search results for "Coughing"

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The COPD multi-dimensional phenotype: A new classification from the STORICO Italian observational study.

2019

BackgroundThis paper is aimed to (i) develop an innovative classification of COPD, multi-dimensional phenotype, based on a multidimensional assessment; (ii) describe the identified multi-dimensional phenotypes.MethodsAn exploratory factor analysis to identify the main classificatory variables and, then, a cluster analysis based on these variables were run to classify the COPD-diagnosed 514 patients enrolled in the STORICO (trial registration number: NCT03105999) study into multi-dimensional phenotypes.ResultsThe circadian rhythm of symptoms and health-related quality of life, but neither comorbidity nor respiratory function, qualified as primary classificatory variables. Five multidimension…

MalePulmonologyPhysiologyComorbidityAnxietyPathology and Laboratory MedicineCohort StudiesPulmonary Disease Chronic ObstructiveMathematical and Statistical TechniquesQuality of lifeMedicine and Health SciencesCoughingCluster AnalysisRespiratory functionPublic and Occupational HealthAged 80 and overCOPDMultidisciplinaryDepressionApplied MathematicsSimulation and ModelingQStatisticsRMiddle AgedExploratory factor analysisCircadian RhythmBody FluidsCircadian RhythmsPhenotypeItalyPhysical SciencesAnxietyMedicineFemalemedicine.symptomAnatomyFactor AnalysisAlgorithmsCohort studyResearch Articlemedicine.medical_specialtyScienceMemory EpisodicChronic Obstructive Pulmonary DiseaseSettore MED/10 - Malattie Dell'Apparato RespiratorioResearch and Analysis MethodsClustering AlgorithmsSigns and SymptomsDiagnostic MedicineInternal medicinemedicineCOPDHumansStatistical MethodsAgedbusiness.industryBiology and Life SciencesPhysical Activitymedicine.diseaseComorbidityrespiratory tract diseasesMucusDyspneaCoughQuality of LifeObservational studybusinessFactor Analysis StatisticalSleepPhysiological ProcessesChronobiologymultiple phenotypesMathematicsPloS one
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Where are patients missed in the tuberculosis diagnostic cascade? A prospective cohort study in Ghana.

2020

BackgroundGhana's national prevalence survey showed higher than expected tuberculosis (TB) prevalence, indicating that many people with TB are not identified and treated. This study aimed to identify gaps in the TB diagnostic cascade prior to starting treatment.MethodsA prospective cohort study was conducted in urban and rural health facilities in south-east Ghana. Consecutive patients routinely identified as needing a TB test were followed up for two months to find out if sputum was submitted and/or treatment started. The causal effect of health facility location on submitting sputum was assessed before risk factors were investigated using logistic regression.ResultsA total of 428 persons …

MaleRural PopulationBacterial DiseasesRNA virusesResearch FacilitiesUrban PopulationPhysiologyHIV InfectionsPathology and Laboratory MedicineGhanaCohort StudiesGeographical Locations0302 clinical medicineImmunodeficiency VirusesHealth facilityHealth careOdds RatioMedicine and Health SciencesCoughingProspective Studies030212 general & internal medicineProspective cohort studyMultidisciplinaryRural healthQRMiddle AgedBody FluidsInfectious DiseasesMedical MicrobiologyResearch DesignViral PathogensVirusesTuberculosis Diagnosis and ManagementMedicineFemaleAnatomyPathogensmedicine.symptomResearch LaboratoriesResearch ArticleCohort studyAdultmedicine.medical_specialtyTuberculosisAdolescentScience030231 tropical medicineResearch and Analysis MethodsMicrobiologyYoung Adult03 medical and health sciencesSigns and SymptomsTuberculosis diagnosisDiagnostic MedicineRetrovirusesmedicineHumansTuberculosisMicrobial PathogensAgedbusiness.industryLentivirusSputumOrganismsBiology and Life SciencesHIVTropical Diseasesmedicine.diseaseMucusFamily medicinePeople and PlacesAfricaSputumHealth FacilitiesPhysiological ProcessesbusinessGovernment LaboratoriesPLoS ONE
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