Search results for "Cover"

showing 9 items of 5959 documents

Tumor targeting of baculovirus displaying a lymphatic homing peptide.

2008

Background Tumor-associated cells and vasculature express attractive molecular markers for site-specific vector targeting. To attain tumor-selective tropism, we recently developed a baculovirus vector displaying the lymphatic homing peptide LyP-1, originally identified by ex vivo/in vivo screening of phage display libraries, on the viral envelope by fusion to the transmembrane anchor of vesicular stomatitis virus G-protein. Methods In the present study, we explored the specificity and kinetics of viral binding and internalization as well as in vivo tumor homing of the LyP-1 displaying virus to elucidate the applicability of baculovirus for targeted therapies. Results We demonstrated that th…

virusesmedia_common.quotation_subjectGenetic VectorsMice NudeBiologyPeptides CyclicVirus03 medical and health sciencesTransduction (genetics)Mice0302 clinical medicineViral envelopeViral Envelope ProteinsIn vivoTransduction GeneticCell Line TumorNeoplasmsDrug DiscoveryGeneticsAnimalsHumansTransgenesInternalizationMolecular BiologyGenetics (clinical)030304 developmental biologymedia_commonLymphatic Vessels0303 health sciencesBinding SitesMembrane GlycoproteinsGene Transfer TechniquesGenetic Therapybiology.organism_classificationMolecular biology3. Good healthCell biologyVesicular stomatitis virus030220 oncology & carcinogenesisMolecular MedicineBaculoviridaeEx vivoHoming (hematopoietic)The journal of gene medicine
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Recovery of mobility function and life-space mobility after ischemic stroke: the MOBITEC-Stroke study protocol

2020

Abstract Background Stroke is a major cause of disability and stroke incidence increases with age. Stroke frequently results in permanent limitations of mobility, and, consequently, the need for the help of others in activities of daily living. In order to optimize rehabilitative efforts and their functional outcomes, detailed knowledge of the functional recovery process, regarding mobility, is needed. Objectives of the MOBITEC-Stroke study are: 1.) To characterize mobility, including lower extremity physical function (LEPF) and life space (the geospatial extent of all of a person’s movements), and changes in mobility within the first year after stroke. 2.) To identify and characterize subg…

walking speed.Quality of lifeAgingaccelerometersGPSClinical Neurologyfyysinen toimintakykyspatial behaviourelämänlaatuWalking speedtoipuminenlcsh:RC346-429aivohalvausmobility limitationStudy ProtocolActivities of Daily Livingcohort studyliikuntakykyQuantitative gait analysisHumans910 Geography & travelquantitative gait analysislcsh:Neurology. Diseases of the nervous systemaskelmittaritRetrospective StudiesagingStroke RehabilitationGeneral MedicineRecovery of FunctionSpatial behaviourMobility limitationkävely10122 Institute of Geography2728 Neurology (clinical)quality of lifepaikkatietojärjestelmätAccelerometersCohort studyikääntyneetBMC Neurology
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Waste heat recovery from a marine waste incinerator using a thermoelectric generator

2012

Published version of an article published in the journal: Journal of Electronic Materials. Also available from the publisher at: http://dx.doi.org/10.1007/s11664-012-2009-6 A marine waste incinerator has been evaluated for waste heat harvesting using thermoelectric generators (TEG). The application has been evaluated using mathematical modeling to optimize the heat exchanger and some vital design parameters of the TEG. The calculation shows that it is possible to extract 58 kW el at a price of 6.6 US$/W from an 850-kW th incinerator when optimizing for maximum power. However, minimizing the cost, it is possible to get 25 kW el at a price of 2.5 US$/W. A trade-off between the two targets lea…

waste heat recoveryMaximum power principleWaste managementVDP::Technology: 500::Marine technology: 580TEGwaste heatCondensed Matter PhysicsthermoelectricElectronic Optical and Magnetic MaterialsIncinerationWaste heat recovery unitThermoelectric generatorWaste heatmarine incineratorThermoelectric effectHeat exchangerMaterials ChemistryEnvironmental scienceElectrical and Electronic Engineeringmathematical model
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Il "linguaggio" della Corte costituzionale: note sparse su alcuni aspetti dell'esperienza recente

2023

Wittgenstein's theories offer the starting point for looking at the socio-political implications of the language spoken by the institutions in the various historical phases: the communication system with which they relate to the outside world is functional in conveying the sense and scope of their action, building a precise relationship with public opinion. Starting from this assumption, the contribution takes into consideration some aspects of the recent practice of the Constitutional Court, with particular regard to press releases, and proposes an interpretation of the communication breakthrough pursued in recent years, relating it to the exercise of the function of warranty.

words language institutional communication public opinion media coverage press releases social consensus guarantee functionSettore IUS/08 - Diritto Costituzionale
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The Effect of Emotional Dissonance and Mental Load on Need for Recovery and Work Engagement among Italian Fixed-Term Researchers

2020

Although many studies have been conducted to evaluate the risk and protective factors on psychological health among academic staff, little attention has been paid to fixed-term researchers, the weakest figures in the academic context. By using the Job Demands&ndash

work engagementHealth Toxicology and MutagenesisEmotionslcsh:MedicineContext (language use)mental loadWorkloadAbsorption (psychology)ArticleJob SatisfactionStructural equation modelingemotional dissonanceuniversityjob resourcesSurveys and Questionnaires0502 economics and businessCognitive dissonanceHumansjob insecurityMental loadBurnout Professionalwork stress factorsWork engagement05 social scienceslcsh:RPublic Health Environmental and Occupational Health050301 educationWorkloadResearch PersonnelTerm (time)need for recoveryItalywork stress factorjob resourcePsychology0503 educationSocial psychology050203 business & management
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Assessment of Knowledge, Attitudes, and Propensity towards HPV Vaccine of Young Adult Students in Italy

2020

Background: Human Papillomavirus (HPV) is a common sexually transmitted infection (STI), representing the main cause of genital warts and cervical cancer. This cross-sectional study evaluated knowledge and attitudes about HPV infection, related diseases, and prevention and propensity towards HPV vaccine among undergraduate students. Methods: An online and written survey about HPV and its prevention, targeted to young adults of both genders, was addressed to students attending health sciences and other schools at Universities of Genoa and Bari. Results: The overall median knowledge and attitude scores were 56.3% (25&ndash

young adultsmedicine.medical_specialtyHPVknowledgeMultivariate analysisstudentImmunologylcsh:MedicineArticleGenital warts03 medical and health sciences0302 clinical medicinepreventionDrug DiscoveryHealth caremedicinePharmacology (medical)030212 general & internal medicinesexually transmitted infectionYoung adultSocioeconomic statusPharmacologyCervical cancerbusiness.industrylcsh:RHPV infectionvirus diseasesmedicine.diseasevaccinationfemale genital diseases and pregnancy complicationspracticeVaccinationInfectious Diseases030220 oncology & carcinogenesisFamily medicineattitudebusinessAttitude; HPV; Knowledge; Practice; Prevention; Sexually transmitted infection; Student; Vaccination; Young adultsVaccines
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Chemical Composition of the Essential Oil of Bupleurum Fontanesii (Apiaceae) Growing Wild in Sicily and its Activity on Microorganisms Affecting Hist…

2016

Hydrodistillation of the flowers (BpFl) of and fruits (BpFr) of Bupleurum fontanesii Guss. ex Caruel gave two oils that were analyzed by GC and GC-MS. The main components were α-elemol (16.7%), caryophyllene oxide (16.4%) and heptacosane (15.9%) in BpFl, and spathulenol (16.8%), caryophylladienol I (13.2%) and α-elemol (12.8%) in BpFr. A good antimicrobial activity against several microorganisms, including Bacillus subtilis, Staphylococcus aureus, Fusarium oxysporum and Aspergillus niger, all infesting historical art craft, was also determined.

α-ElemolBupleurumAntifungal AgentsMicroorganismPlant ScienceBacillus subtilis01 natural scienceslaw.inventionlawVolatile componentDrug DiscoveryBotanyFusarium oxysporumOils VolatilePlant OilsSicilyEssential oilPharmacologyApiaceaeBacteriaBupleurum fontanesiibiology010405 organic chemistryDrug Discovery3003 Pharmaceutical ScienceAspergillus nigerFungiSpathulenolfood and beveragesGeneral MedicineComplementary and Alternative Medicine2708 DermatologyAntimicrobialbiology.organism_classificationAnti-Bacterial AgentsBupleurum0104 chemical sciences010404 medicinal & biomolecular chemistryCaryophyllene oxideComplementary and alternative medicineArtApiaceaeNatural Product Communications
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Discovery of α2β1 integrin ligands : tools and drug candidates for cancer and thrombus

2011

α2β1-integriiniliganditintegriinitintegriinisalpaajatα2β1 integrinthrombusrational drug discoverysyöpäkollageenitliganditveritulppacollagen receptor integrinsfarmakoforitX-ray crystallography
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La grammaire à l’école élémentaire française : un enseignement sous tension…

2022

La question de l’enseignement de la langue à l’école reste sensible en France et entraine régulièrement des débats et des controverses qui dépassent le cadre scolaire. La grammaire cristallise ces oppositions tant au niveau linguistique, didactique et pédagogique, politique, institutionnel, social… Nous sommes de fait face à un enseignement sous tension. Notre proposition tentera d’interroger et de croiser deux dimensions, les savoirs prescrits et les savoirs enseignés. Cette mise en interaction se fera selon deux axes: sur un axe diachronique, nous proposerons une analyse de quelques textes institutionnels qui se succèdent depuis vingt ans pour comprendre les attentes ministérielles dans u…

“UNESCO:CIENCIAS DE LAS ARTES Y LAS LETRAS”Linguistics and Languagepronoms anafòricsdiscovery-learninglaboratori de gramàticaexplicit knowledge of languagegrammar laboratoryanaphoric pronounsaprenentatge per descobrimentLanguage and Linguisticsconeixement explícit de la llenguaCaplletra. Revista Internacional de Filologia
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