Search results for "Craving"

Lo spettro impulsivo-compulsivo nell’addiction: una prospettiva in- tegrata sullo sviluppo delle dipendenze patologiche in adolescenza

2008

The evaluation of alcohol use disorder is the important first stage of interven- tions and treatments. The S.A.I.D. is an auto-evaluation test built on the assumption that alcoho- lism is close connected to the other person’s life problems that may have contributed to rouse, exacerbate or maintain alcoholism. The test is composed of 39 items, presented as auto-descriptions, that provide patient’s diagnostic profile articulated in two specific areas (social area and psycho- logical area), each divided in 9 scales (work/study; relationships; social relation- ship; cure/physical health; depression; hostility; inattention, anxiety,alexitimya) investigated through specific behavioural indexes th…

Internet and computer game addiction - a review of current neuroscientific research

2011

IntroductionA significant part computer game players and internet users show clinical features of abuse and addiction (loss of control, withdrawal symptoms, tolerance, continuation of game play even with increasing negative consequence in social and academic life). Similar mechanisms are suggested to underlie the pathogenesis and maintenance of internet and computer game addiction and substance-related addictions.ObjectivesNeuroscientific research on internet and computer game addiction is sparse, yet emerging. To review previous studies is the objective of the present project.AimsWe aim to identify common findings regarding the neurophysiological processes underlying internet and computer …

2018

Eating disorders (EDs) are characterized by marked cognitive distortions and maladaptive schemas. Cognitive models of EDs highlight the direct impact of cognitive dysfunctions on eating-related disturbances, insofar as specific cognitive contents such as thoughts about diet rules and food or loss of control may trigger disturbed eating behavior. Moreover, early maladaptive schemas that reflect perfectionist standards and relate to achievement and performance seem to be associated with disturbed eating, e.g., via their impact on situation-specific appraisals. However, so far, no study has investigated these assumptions. Hence, the present study sought to demonstrate whether and how cognitive…

Slow release oral morphine versus methadone for the treatment of opioid use disorder

2019

ObjectiveTo assess the efficacy of slow release oral morphine (SROM) as a treatment for opioid use disorder (OUD).DesignSystematic review and meta-analysis of randomised controlled trials (RCTs).Data sourcesThree electronic databases were searched through 1 May 2018: the Cochrane Central Register of Controlled Trials, MEDLINE and EMBASE. We also searched the following electronic registers for ongoing trials: ClinicalTrials.gov, WHO International Clinical Trials Registry Platform, Current Controlled Trials and the EU Clinical Trials Register.Eligibility criteria for selecting studiesWe included RCTs of all durations, assessing the effect of SROM on measures of treatment retention, heroin use…

Addiction Research Unit: Affective and cognitive mechanisms of specific Internet‐use disorders

2021

In the eleventh International Classification of Diseases (ICD-11) of the World Health Organization, gambling disorder and gaming disorder are included in the category 'disorders due to addictive behaviours', which can be specified further as occurring either predominantly offline or predominantly online. Other specific problematic behaviours may be considered for the category 'other specified disorders due to addictive behaviours'. The Research Unit FOR 2974, funded by the German Research Foundation (Deutsche Forschungsgemeinschaft, DFG), focuses on the most prominent online addictive behaviours: gaming, pornography use, buying-shopping and social-networks use. The main goal of the Research…

Smartphone Addiction Inventory (SPAI): Psychometric properties and confirmatory factor analysis

2016

The Smartphone Addiction Inventory (SPAI) was developed to assess smartphone addiction in Taiwanese university students. The purpose of the current research is to evaluate the factor structure and psychometric properties of the SPAI in Italian university students. A total of 485 university students (29.3% boys) completed the SPAI and the Young's Internet Addiction Test (IAT).The proposed four-factor model of the SPAI-I was tested by computing CFA, and the results of the goodness of fit indices indicated an ambiguous solution. An exploratory-confirmatory cross validation strategy was applied for a better trimming of SPAI-I factorial structure. Results suggested a five-factor solution that ex…

Two‐year effect of semaglutide 2.4 mg on control of eating in adults with overweight/obesity: STEP 5

2023

Background: The STEP 5 trial (NCT03693430) investigated once-weekly (OW) subcutaneous semaglutide 2.4 mg vs placebo for the treatment of overweight/obesity in adults over 2 years. Methods: Adults w ith B MI ≥ 3 0 k g/m2, or ≥27 kg/m2 and ≥ 1 weight-related comorbidity, without diabetes, were randomized 1:1 to semaglutide 2.4 mg OW or placebo for 104 weeks. Co-primary endpoints related to body weight (BW) changes. Control of eating questionnaire (CoEQ) was assessed in a subgroup from Canada/USA, with scores from 19 individual items grouped into 4 domains: craving control, craving for savory, craving for sweet, or positive mood. P values for exploratory CoEQ data are unadjusted for multiplici…

Narcissistic Tendencies Among Actors

2014

Building on a two-dimensional reconceptualization of grandiose narcissism, we investigated how narcissistic admiration (the tendency toward agentic self-promotion) and rivalry (the tendency toward other derogation) are related to acting. Study 1 ( N = 583) showed that acting students scored higher on narcissistic admiration than students with other majors, but at the same time, the acting students scored lower on rivalry. In Study 2 ( N = 283), we compared improvisational theater actors with a comparison group and found the same pattern: Admiration was higher, but rivalry was lower among the actors (across both self-reports and informant reports). Effects persisted when we controlled for s…

Effect of adolescent exposure to WIN 55212-2 on the acquisition and reinstatement of MDMA-induced conditioned place preference.

2009

The present study employs a conditioned place preference procedure (CPP) to examine the effects of exposure to the cannabinoid agonist WIN 55212-2 (WIN) (0.1 and 0.5mg/kg) during adolescence on the reinforcing properties of +/-3,4-methylenedioxymetamphetamine hydrochloride (MDMA) (1.25 and 2.5mg/kg) in mice. On postnatal day (PD) 27, animals received a daily injection of the assigned treatment on 5 consecutive days, and three days later the place conditioning procedure was initiated (PD 35). The results suggest that pre-exposure to cannabinoids strengthens the properties of MDMA and favors reinstatement of the craving for the drug, which endorses the gateway hypothesis.

Exercise as an Adjuvant Intervention in Opiate Dependence

2013

We read with interest the article by Weinstock et al. in whichthe authors propose exercise as an adjuvant intervention inopiate agonist treatment based on current research findings(1).The use of an opiate agonist, such as buprenorphine, butmainly, methadone, for the treatment of opiate dependenceis currently an effective therapy for this type of addiction.The main benefits of this treatment occur through a relieffrom craving narcotic drugs, a temporally suppression ofwithdrawal symptoms, and by blocking the euphoric effectsof opiates (2). Unfortunately, patients needing treatment foropiatedependenceoftenfaceavarietyofco-occurringissues,suchashepatitisBandCvirusesorhumanimmunodeficiencyvirus (H…