Search results for "Critica"

showing 10 items of 4441 documents

[Prognostic value of interleukin 6 for death of patients with sepsis].

2016

Abstract Background and objective To see the influence of interlukin-6 (IL-6) as an inflammatory mediator in patients with systemic inflammatory response syndrome (SIRS) and sepsis, assessing whether their serum levels during their stay in intensive care unit (ICU) serve as an early mortality prognostic marker. Material and methods A prospective observational cohort study with 203 ICU patients from a third level hospital. A descriptive analysis was made, X 2 test used to compare qualitative variables, T -Student test to compare quantitative ones. We made a logistic regression multivariant analysis on admission, third and seventh day of stay with dependent variable mortality and independent …

AdultMalemedicine.medical_specialtyLogistic regressionSensitivity and SpecificitySeverity of Illness Indexlaw.inventionSepsis03 medical and health sciences0302 clinical medicinelawInternal medicineSepsismedicineHumans030212 general & internal medicineLongitudinal StudiesProspective StudiesSurvival analysisAgedAged 80 and overAPACHE IIbusiness.industryInterleukin-6030208 emergency & critical care medicineMiddle Agedmedicine.diseasePrognosisIntensive care unitSurgerySystemic inflammatory response syndromeLogistic ModelsEtiologyFemalebusinessBiomarkersCohort studyMedicina clinica
researchProduct

Stratified Care vs Step Care Strategies for Migraine

2000

ContextVarious guidelines recommend different strategies for selecting and sequencing acute treatments for migraine. In step care, treatment is escalated after first-line medications fail. In stratified care, initial treatment is based on measurement of the severity of illness or other factors. These strategies for migraine have not been rigorously evaluated.ObjectiveTo compare the clinical benefits of 3 strategies: stratified care, step care within attacks, and step care across attacks, among patients with migraine.Design and SettingRandomized, controlled, parallel-group clinical trial conducted by the Disability in Strategies Study group from December 1997 to March 1999 in 88 clinical cen…

AdultMalemedicine.medical_specialtyMetoclopramideMigraine DisordersPopulationZolmitriptanSeverity of Illness IndexDrug Administration Schedulelaw.inventionRandomized controlled triallawInternal medicineSeverity of illnessHumansMedicineeducationOxazolidinonesAspirineducation.field_of_studyAspirinbusiness.industryAnti-Inflammatory Agents Non-SteroidalArea under the curveGeneral MedicineMiddle Agedmedicine.diseaseTryptaminesSerotonin Receptor AgonistsClinical trialMigraineCritical PathwaysPhysical therapyDopamine AntagonistsFemalebusinessmedicine.drugJAMA
researchProduct

Emergency toe-to-hand transfer for post-traumatic finger reconstruction: A multicenter case series

2019

Abstract Background The aim of this paper was to evaluate the outcomes of a homogenous series of emergency with a toe-to-hand transfer reconstructions with a different timing: immediate (same surgical step with the debridement), primary (in the first 24 h), early (24–72 h after the debridement) or delayed (72 h-7 days). Materials and methods Between 2001 and 2011, 31 patients received an immediate reconstruction with a toe-to-hand transfer. Data on indications, timing, type of surgery, complications and outcomes (sensory and motor recovery, patient satisfaction) were extrapolated and recorded. Results Most of the procedures in our series (71%) were performed in the first 24 h. Survival rate…

AdultMalemedicine.medical_specialtyMicrosurgeryTime FactorsAdolescentSettore MED/19 - Chirurgia PlasticaThumb03 medical and health sciencesYoung AdultImmediate reconstruction0302 clinical medicinePatient satisfactionAmputation TraumaticFinger InjuriesmedicineHumansRange of Motion ArticularChildSurvival rateGeneral Environmental Science030222 orthopedicsSeries (stratigraphy)Emergency microsurgerybusiness.industryToe-to-hand transfer030208 emergency & critical care medicineRecovery of FunctionMiddle AgedPlastic Surgery ProceduresToesmedicine.disease3. Good healthSurgeryVenous thrombosisDissectionmedicine.anatomical_structureTreatment OutcomeSatisfaction rateThumbPatient SatisfactionChild PreschoolFinger reconstructionGeneral Earth and Planetary SciencesMotor recoveryFemaleEmergenciesbusinessFollow-Up Studies
researchProduct

A Prognostic Enrichment Strategy for Selection of Patients With Acute Respiratory Distress Syndrome in Clinical Trials.

2019

Incomplete or ambiguous evidence for identifying high-risk patients with acute respiratory distress syndrome for enrollment into randomized controlled trials has come at the cost of an unreasonable number of negative trials. We examined a set of selected variables early in acute respiratory distress syndrome to determine accurate prognostic predictors for selecting high-risk patients for randomized controlled trials.A training and testing study using a secondary analysis of data from four prospective, multicenter, observational studies.A network of multidisciplinary ICUs.We studied 1,200 patients with moderate-to-severe acute respiratory distress syndrome managed with lung-protective ventil…

AdultMalemedicine.medical_specialtyOrgan Dysfunction ScoresMEDLINEAcute respiratory distressCritical Care and Intensive Care Medicinelaw.inventionRandomized controlled triallawMedicineHumansProspective StudiesIntensive care medicineProspective cohort studySelection (genetic algorithm)AgedRandomized Controlled Trials as TopicRespiratory Distress Syndromebusiness.industryPatient SelectionAge FactorsMiddle AgedPrognosisClinical trialMulticenter studyObservational studyFemalebusinessCritical care medicine
researchProduct

Stratification for Identification of Prognostic Categories In the Acute RESpiratory Distress Syndrome (SPIRES) Score.

2021

OBJECTIVES: To develop a scoring model for stratifying patients with acute respiratory distress syndrome into risk categories (Stratification for identification of Prognostic categories In the acute RESpiratory distress syndrome score) for early prediction of death in the ICU, independent of the underlying disease and cause of death. DESIGN: A development and validation study using clinical data from four prospective, multicenter, observational cohorts. SETTING: A network of multidisciplinary ICUs. PATIENTS: One-thousand three-hundred one patients with moderate-to-severe acute respiratory distress syndrome managed with lung-protective ventilation. INTERVENTIONS: None. MEASUREMENTS AND MAIN …

AdultMalemedicine.medical_specialtyOrgan Dysfunction ScoresPsychological interventionMEDLINECritical Care and Intensive Care MedicineLogistic regressionSeverity of Illness IndexstratificationInternal medicinemedicineHumansProspective StudiesCause of deathAPACHEclinical trialsRespiratory Distress SyndromeReceiver operating characteristicbusiness.industryphenotypesscoring systemacute respiratory distress syndromeMiddle AgedPrognosisRespiration ArtificialIntensive Care UnitsROC CurveSpainArea Under CurveCohortBreathingoutcomeObservational studyFemalebusinessCritical care medicine
researchProduct

Attitudes towards end-of-life issues in intensive care unit among Italian anesthesiologists: a nation-wide survey

2018

Background: The aim of this paper is to collect data on the practice of palliative care, withholding and withdrawal of life-sustaining therapies, and management of end of life (EOL) in Italian intensive care units (ICUs). Methods: Web-based survey among Italian anesthesiologists endorsed by the Italian Society of Anesthesiology Analgesia Reanimation and Intensive Care (SIAARTI). The survey consists of 27 close-ended and 2 open-ended questions. Results: Eight hundred and five persons responded to the full list of questions. The highest proportion of respondents was of 36–45 years of age (34%) and catholic (66%). Almost 70% of responders declared that palliative/supportive care are applied …

AdultMalemedicine.medical_specialtyPalliative carePain medicinelaw.invention03 medical and health sciencesEnd-of-life care; Intensive care unit; Life-sustaining treatments; Palliative care0302 clinical medicinelawAnesthesiologyIntensive careSurveys and QuestionnairesmedicineSurveys and QuestionnaireHumansLife-sustaining treatmentIntensive care unit030212 general & internal medicineMED/41 - ANESTESIOLOGIATerminal Carebusiness.industryCritically illNursing research030208 emergency & critical care medicineLife-sustaining treatmentsMiddle AgedIntensive care unitAnesthesiologistsIntensive Care UnitsAttitudeItalyOncologyEnd-of-life careFamily medicinePalliative careFemaleAnesthesiologistbusinessEnd-of-life careHuman
researchProduct

Socio-economic cost and health-related quality of life of burn victims in Spain

2008

Abstract Objectives The aim of the study was to determine the economic burden (direct and indirect costs) of burn victims and the impact of burn on health-related quality of life in Spain. Methods In 2003, a cross-sectional study was carried out with 898 burned people. Data regarding demographic features, health resource use, informal care, indirect costs and quality of life were prospectively collected through hospital admission databases and questionnaires filled out by burn victims and caregivers. Results The mean annual cost (direct and indirect) per burn patient was US$ 99,773. The most important categories of costs were those of in-patient care and temporary and permanent disability. …

AdultMalemedicine.medical_specialtyPoison controlCritical Care and Intensive Care MedicineOccupational safety and healthIndirect costsQuality of life (healthcare)Cost of IllnessSurveys and QuestionnairesEnvironmental healthHealth caremedicineHumansProspective Studieshealth care economics and organizationsHealth policyCost–utility analysisbusiness.industryPublic healthHealth Care CostsGeneral MedicineSurgeryHospitalizationCross-Sectional StudiesCaregiversSocioeconomic FactorsSpainQuality of LifeEmergency MedicineFemaleSurgeryBurnsbusinessBurns
researchProduct

A Randomized-Controlled Study of Intrathecal Versus Epidural Thoracic Analgesia in Patients Undergoing Abdominal Cancer Surgery

2008

Background. We sought to determine the effectiveness of continuous intrathecal thoracic analgesia (ITA) in comparison with continuous epidural thoracic analgesia (ETA) for the management of postoperative pain after abdominal cancer surgery in a randomised controlled study. Materials and methods. Catheters were inserted at T8-10 level for both techniques. Sixty patients were randomized to receive ITA providing levobupivacaine 0.25%, at 0.5-0-7 ml/h, associated with a single bolus of morphine 0.15 mg, or ETA with levobupivacaine 0.25% 4-6 ml/h and a single bolus of epidural morphine 2-3 mg. Data were collected before discharging from recovery room to the surgical ward, 1, 2, 3, 8, 12, 24 h, a…

AdultMalemedicine.medical_specialtyResuscitationAdolescentabdominal cancer surgerySettore MED/41 - AnestesiologiaDiuresisHemodynamicsHealth Informaticsepidural analgesiaintrathecal analgesiapostoperative painCritical Care and Intensive Care Medicineintrathecal analgesialaw.inventionYoung AdultRandomized controlled triallawIntensive careAnesthesiologymedicineHumansAnesthetics LocalInjections SpinalAgedPain MeasurementAged 80 and overPain Postoperativebusiness.industryLidocaineepidural analgesiaMiddle AgedSurgeryAnalgesia EpiduralTreatment OutcomeAnesthesiology and Pain MedicineLevobupivacaineAbdominal NeoplasmsAnesthesiaMorphineFemalebusinessmedicine.drugJournal of Clinical Monitoring and Computing
researchProduct

Transverse sacral fracture with intrapelvic intrusion of the lumbosacral spine: case report and review of the literature.

2000

AdultMalemedicine.medical_specialtySacrumLumbosacral spineCritical Care and Intensive Care MedicineIntrusionFracture Fixation InternalFractures BoneMedicineHumansSpinal Cord InjuriesPelvic girdleLumbar Vertebraebusiness.industryLaminectomyAnatomySacrumSacral fractureRadiographyOrthopedic surgerySpinal FracturesSurgeryLumbar spinebusinessBone PlatesLumbosacral jointThe Journal of trauma
researchProduct

Nurses' decision-making, practices and perceptions of patient involvement in medication administration in an acute hospital setting.

2019

To describe nurses' decision-making, practices and perceptions of patient involvement in medication administration in acute hospital settings.Medication errors cause unintended harm to patients. Nurses have a major role in ensuring patient safety in medication administration practices in hospital settings. Investigating nurses' medication administration decision-making and practices and their perceptions of patient involvement, may assist in developing interventions by revealing how and when to involve patients during medication administration in hospital.A descriptive exploratory study design.Twenty nurses were recruited from two surgical and two medical wards of a major metropolitan hospi…

AdultMalemedicine.medical_specialtySafety ManagementCritical CareDecision MakingPsychological interventionExploratory researchNursing Staff Hospital03 medical and health sciencesPatient safetyYoung Adult0302 clinical medicinemedicineHumansMedication Errors030212 general & internal medicinePatient participationCase report formGeneral Nursing030504 nursingDescriptive statisticsbusiness.industryAustraliaMiddle AgedHarmFamily medicineFemaleThematic analysisPatient Participation0305 other medical sciencebusinessNurse-Patient RelationsJournal of advanced nursing
researchProduct