Search results for "Croatia"

showing 10 items of 59 documents

Application of Cell Culture for the Production of Bioactive Compounds from Sponges:  Synthesis of Avarol by Primmorphs from Dysidea avara

2000

Among all metazoan phyla, sponges are known to produce the largest number of bioactive compounds. However, until now, only one compound, arabinofuranosyladenine, has been approved for application in humans. One major obstacle is the limited availability of larger quantities of defined sponge starting material. Recently, we introduced the in vitro culture of primmorphs from Suberites domuncula, which contain proliferating cells. Now we have established the primmorph culture also from the marine sponge Dysidea avara and demonstrate that this special form of sponge cell aggregates produces avarol, a sesquiterpenoid hydroquinone, known to display strong cytostatic activity especially against ma…

CroatiaCell Culture TechniquesPharmaceutical ScienceAntineoplastic AgentsSecondary metaboliteAntiviral AgentsAnalytical Chemistrychemistry.chemical_compoundBiosynthesisDrug DiscoverymedicineAnimalsIncubationChromatography High Pressure LiquidCell AggregationElectrophoresis Agar GelPharmacologybiologySecondary metabolites. Suberites domuncula. Geodia-cydonium. MarineOrganic ChemistryDNAbiology.organism_classificationIn vitroTerpenoidPoriferaSuberites domunculaSpongeComplementary and alternative medicinechemistryBiochemistryCell cultureRNAMolecular MedicineSpectrophotometry UltravioletChromatography Thin LayerSesquiterpenesThymidinemedicine.drugJournal of Natural Products
researchProduct

Toll-like receptors are part of the innate immune defense system of sponges (demospongiae: Porifera).

2006

During evolution and with the emergence of multicellular animals, the need arose to ward off foreign organisms that threaten the integrity of the animal body. Among many different receptors that participate in the recognition of microbial invaders, toll-like receptors (TLRs) play an essential role in mediating the innate immune response. After binding distinct microbial components, TLRs activate intracellular signaling cascades that result in an induced expression of diverse antimicrobial molecules. Because sponges (phylum Porifera) are filter feeders, they are abundantly exposed to microorganisms that represent a potential threat. Here, we describe the identification, cloning, and deduced …

CroatiaMolecular Sequence Datachemistry.chemical_compoundGeneticsAnimalsCluster AnalysisAmino Acid SequenceReceptorMolecular BiologyEcology Evolution Behavior and SystematicsIn Situ HybridizationPhylogenyDeath domainDNA PrimersToll-like receptorInnate immune systembiologyBase SequenceEffectorToll-Like ReceptorsLipopeptideSequence Analysis DNAbiology.organism_classificationBlotting NorthernImmunohistochemistryImmunity InnateCell biologyPoriferaSuberites domunculaInterleukin-1 Receptor-Associated KinaseschemistryCaspasesImmunologySignal transductionMolecular biology and evolution
researchProduct

High-Density Genomic Characterization of Native Croatian Sheep Breeds

2022

A recent comprehensive genomic analysis based on 50K SNP profiles has shown that the regional Balkan sheep populations have considerable genetic overlap but are distinctly different from surrounding breeds. All eight Croatian sheep breeds were represented by a small number of individuals per breed. Here, we genotyped 220 individuals representing the native Croatian sheep breeds (Istrian Sheep, Krk Island Sheep, Cres Island Sheep, Rab Island Sheep, Lika Pramenka, Pag Island Sheep, Dalmatian Pramenka, Dubrovnik Sheep) and mouflon using the Ovine Infinium® HD SNP BeadChip (606,006 SNPs). In addition, we included publicly available Balkan Pramenka and other Mediterranean sheep breeds. Our analy…

Croatian sheep breedCroatian sheep breedsGeneticsMolecular MedicineinbreedingGenetics(clinical)population structuregenomic characterizationGenetics (clinical)effective population sizepopulationstructure
researchProduct

High-density genomic characterization of native Croatian sheep breeds

2022

A recent comprehensive genomic analysis based on 50K SNP profiles has shown that the regional Balkan sheep populations have considerable genetic overlap but are distinctly different from surrounding breeds. All eight Croatian sheep breeds were represented by a small number of individuals per breed. Here, we genotyped 220 individuals representing the native Croatian sheep breeds (Istrian Sheep, Krk Island Sheep, Cres Island Sheep, Rab Island Sheep, Lika Pramenka, Pag Island Sheep, Dalmatian Pramenka, Dubrovnik Sheep) and mouflon using the Ovine Infinium® HD SNP BeadChip (606, 006 SNPs). In addition, we included publicly available Balkan Pramenka and other Mediterranean sheep breeds. Our anal…

Croatian sheep breeds ; effective population size ; genomic characterization ; inbreeding ; population structure
researchProduct

Peuples constitutifs et identités linguistiques en Bosnie-Herzégovine

2015

CroatianBosnianPolitical sciencelanguageGeneral Earth and Planetary SciencesEthnologySerbianlanguage.human_languageGeneral Environmental ScienceRoczniki Humanistyczne
researchProduct

Landscape, resources and vegetal economy in the Parentium zone (I-V c. AD). First results of a palaeobotanic research

2016

International audience

CroatiePaléobotanique[SHS.ARCHEO] Humanities and Social Sciences/Archaeology and PrehistoryGestion des ressources[SHS.ARCHEO]Humanities and Social Sciences/Archaeology and PrehistoryCroatia[SHS] Humanities and Social SciencesComputingMilieux_MISCELLANEOUSpaleobotanicResource economy[SHS]Humanities and Social Sciences
researchProduct

Pamięci nieukojone. Wokół upamiętniania ofiar w Serbii i Chorwacji (Jasenovac, Bleiburg i belgradzkie Sajmište)

2016

Tekst koncentruje się na przemianach tożsamości narodowych w dwóch krajach postjugosłowiańskich (Serbii i Chorwacji). (Re)konstrukcje przeszłości mające tam miejsce od lat dziewięćdziesiątych XX wieku zakładały przede wszystkim zanegowanie dziedzictwa wspólnego opartego na zmitologizowanej walce partyzanckiej, a następnie wybór z przeszłości tych wydarzeń, o których pamięć należy kultywować. Walka przeciwstawnych pamięci (serbskiej i chorwackiej) oraz polaryzacja społeczeństwa chorwackiego pokazana zostaje na przykładzie praktyk komemoratywnych związanych z miejscami zagłady (Jasenovac i Bleiburg) z okresu drugiej wojny światowej. W tekście przywołano również miejsce kojarzone z Holokaustem…

Cultural StudiesCroatianHistoryLiterature and Literary Theorymedia_common.quotation_subjectWorld War IIPolarization (politics)MythologyAncient historylanguage.human_languageSymbolThe HolocaustlanguageSerbianmedia_commonPorównania
researchProduct

Memory in action – Performative practices in a dispute about the past: Serbia and Croatia at the turn of the 20th and 21st century

2019

Memory in action – Performative practices in a dispute about the past: Serbia and Croatia at the turn of the 20th and 21st centuryThe article is an attempt to combine in one reflection the elements of two directions of critical thinking: discursive and performative. The starting point of the analysis is the assumption (derived from beliefs common in pre-performative times) that every space (including a city’s territory) can be treated as a text. This means that both static artifacts and activities in a given space communicate a certain message and can be seen as signs or symbols that refer to something outside of them. Our reflection focuses on practices in which the performative potential …

Cultural StudiesCroatianlcsh:Ethnology. Social and cultural anthropologyLinguistics and LanguageHistoryperformative practicesLiterature and Literary Theorylcsh:PG1-9665Performative utteranceLanguage and Linguisticslanguage.human_languagecroatiamemorylcsh:GN301-674AnthropologyPolitical sciencelcsh:Slavic languages. Baltic languages. Albanian languageslanguagediscourseserbiaTheologySerbianSlavia Meridionalis
researchProduct

The Saving Narratives of Daša Drndić

2018

The starting point for this paper is the assumption that by obsessive revisiting the events of World War II, the Croatian writer Dasa Drndic attempts to influence indirectly the present. It parallels her narrators’ declarations who—with a great dose of probability—can be simultaneously read as her alter egos. Hence, the article investigates and describes the strategy whose main aim is to retain memory about the past. In Drndic’s texts this function is achieved through the acts of archiving, writing down, and grouping. These acts constitute non-standard ways to enhance the literary text with, for example, whole pages filled with the victims’ names (integrated within the text or acting as a p…

Cultural StudiesLiteratureHistoryHistoryPoint (typography)business.industryHolocaustmedia_common.quotation_subjectWorld War IIReligious studiesethicsmemorychildrenThe HolocaustCroatian literatureNarrativeFunction (engineering)businessParallelsarchivesmedia_commonStudia Judaica
researchProduct

Chińska aktywność na Bałkanach w XXI wieku i jej implikacje

2022

Celem artykułu jest szkicowe przedstawienie, na podstawie analiz i materiałów prasowych, wielosektorowej obecności Chin na Bałkanach i jej wpływu na sytuację ekonomiczną regionu. Bałkany są ważne dla mocarstw ze względu na położenie geopolityczne i geostrategiczne na skrzyżowaniu szlaków międzykontynentalnych. Chiny znacząco wpływają na ekonomikę poszczególnych państw region, wykorzystując dyplomację publiczną celem ograniczenia wpływów ze strony innych ważnych graczy: Unii Europejskiej, Rosji i USA. Autorka przedstawia hipotezę, że Chiny, tak jak USA pod koniec XX wieku, zmierzają do stworzenia sfery wpływów na Półwyspie Bałkańskim, w kontekście swoich interesów globalnych. Bałkany są post…

CzarnogóraChinaBułgariaBałkanyCroatiaNorthern MacedoniaBalkansChinypasywathe United StatesGeneral MedicinePółnocna MacedonialiabilitiesMontenegroChorwacjaStany Zjednoczonespheres of influenceeconomic investmentsstrefy wpływówBulgariaSerbiainwestycje ekonomiczneBalcanica Posnaniensia. Acta et studia
researchProduct