Search results for "Crohn's Disease"

showing 10 items of 242 documents

Is splenectomy a treatment option for aseptic abscesses in patients with Crohn's disease?

2009

Splenectomy aseptic abscesses Crohn's disease
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Vitamin K Deficit leads to Chronic Inflammatory Bowel Disease Diagnosis: a case report

2014

Vitamin K Crohn's disease
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Hypoxia Positively Regulates the Expression of pH-Sensing G-Protein–Coupled Receptor OGR1 (GPR68)

2016

Background & Aims: A novel family of proton-sensing G-proteinâcoupled receptors, including ovarian cancer G-proteinâcoupled receptor 1 (OGR1) (GPR68) has been identified to play a role in pH homeostasis. Hypoxia is known to change tissue pH as a result of anaerobic glucose metabolism through the stabilization of hypoxia-inducible factor-1α. We investigated how hypoxia regulates the expression of OGR1 in the intestinal mucosa and associated cells. Methods: OGR1 expression in murine tumors, human colonic tissue, and myeloid cells was determined by quantitative reverse-transcription polymerase chain reaction. The influence of hypoxia on OGR1 expression was studied in monocytes/macrophages and…

WT wild type0301 basic medicineMM6 MonoMac 6HV healthy volunteerSPARC secreted protein acidic and rich in cysteineNF-κB nuclear factor-κBInflammationBiologyIEC intestinal epithelial cell03 medical and health sciencesIntestinal mucosaTDAG8Ovarian Cancer G-Protein–Coupled ReceptormedicineOGR1 ovarian cancer G-protein–coupled receptor 1 (GPR68)IFN interferonlcsh:RC799-869ReceptorOriginal ResearchTh T-helperInflammationTNF tumor necrosis factorIBD inflammatory bowel diseaseHepatologyRT-qPCR quantitative reverse-transcription polymerase chain reactionAICAR 5-aminoimidazole-4-carboxamide-1-β-4-ribofuranosideTDAG8 T-cell death-associated gene 8 (GPR65)Inflammatory Bowel DiseaseGRP65GastroenterologyHypoxia (medical)Molecular biologyGPR G-protein–coupled receptormRNA messenger RNAIL interleukinChIP chromatin immunoprecipitationHIF hypoxia-inducible factorUC ulcerative colitis030104 developmental biologyHypoxia-inducible factorsCancer researchCD Crohn's diseaselcsh:Diseases of the digestive system. GastroenterologyTumor necrosis factor alphaFCS fetal calf serummedicine.symptomChromatin immunoprecipitationHomeostasisCellular and Molecular Gastroenterology and Hepatology
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Prevalence of endodontic infection in patients with Crohn ́s disease and ulcerative colitis

2021

[Background] Previous studies have linked apical periodontitis (AP) to inflammatory bowel disease (IBD). The aim of this study was to compare the prevalence of AP and root canal treatment (RCT) in patients with ulcerative colitis (UC) and Crohn ́s disease (CD).

burning mouth syndromeCrohn’s diseasemedicine.medical_specialtyMultivariate analysisRoot canalefficacyDiseaseLogistic regressionInflammatory bowel diseaseGastroenterologyInflammatory bowel disease03 medical and health sciences0302 clinical medicinesystematic reviewCrohn DiseaseToot canal treatmentApical periodontitisInternal medicinePrevalencemedicineHumansGeneral DentistryUNESCO:CIENCIAS MÉDICASPeriodontitisCrohn's diseaseOral Medicine and Pathologybusiness.industryResearch030206 dentistrylow level laser therapymedicine.diseaseUlcerative colitisdigestive system diseasesRoot Canal TherapyCross-Sectional Studiesmedicine.anatomical_structureOtorhinolaryngologyUlcerative colitisColitis UlcerativeSurgerybusinessPeriapical Periodontitis
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Efficacy of non-surgical periodontal treatment on patients with coronary artery disease: a meta-analysis of randomized controlled trials

2022

Coronary artery disease (CAD) is defined as one of the most common cardiovascular diseases (CVDs). Periodontitis is one of the risk factors for CAD. PubMed, Embase and Cochrane Library databases were carefully and thoroughly retrieved until October 2021. On the basis of the inclusion and exclusion criteria, eligible articles were selected strictly to identify randomized controlled trials (RCTs). Using Cochran's Q statistic, Review Manager 5.4 and Stata 16, data were extracted, and a comprehensive analysis was carried out. Six RCTs of 619 patients were included in this study, including 360 in the intervention group (IG) and 259 in the control group (CG). Meta-analysis showed significant diff…

crohn's diseaseCholesterol HDLCoronary Artery DiseaseCholesterol LDLaphthous stomatitisC-Reactive ProteinOtorhinolaryngologyinflammatory bowel diseasesystemic extraintestinal manifestationsHumansSurgeryundeterminedGeneral DentistryUNESCO:CIENCIAS MÉDICASTriglyceridesulcerative colitisRandomized Controlled Trials as TopicMedicina Oral Patología Oral y Cirugia Bucal
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Severe cutaneous psoriasis after certolizumab pegol treatment;report of a case.

2009

crohn's diseasePsoriasisCerolizumab
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Oral lichen planus after certolizumab pegol treatment in a patient with Crohn's disease

2011

Dear Sir , Lichen planus (LP) is a relatively uncommon inflammatory dermatosis of the mucocutaneous surfaces that can present with a variety of clinical manifestations and, most commonly, affecting middle-aged adults. The disease course may be short or chronic, although most cases may resolve after 1 month to 7 years. The real prevalence of LP is unknown, but is estimated to be 1% in the USA.1 The pathogenesis of LP is not entirely understood. In general, activated T lymphocytes are recruited to the dermal–epidermal junction and induce apoptosis in basal keratinocytes. Both CD4+ and CD8+ T lymphocytes are found in the lichenoid infiltrate of LP, with a predominance of the latter cell type b…

education.field_of_studyCrohn's diseasemedicine.medical_specialtySettore MED/09 - Medicina Internaintegumentary systembusiness.industryPopulationMucocutaneous zoneoral lichen planu certolizumab crohnGastroenterologyGeneral Medicinemedicine.diseaseDermatologyPathogenesisstomatognathic diseasesBasal (phylogenetics)medicineOral lichen planusCertolizumab pegoleducationbusinessCD8medicine.drugJournal of Crohn's and Colitis
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Course of Crohn’s Disease

2015

Crohn’s disease (CD) is an inflammatory bowel disease with a chronic course and it is characterized by different events within time, which are in relation to the heterogeneity of the disease. The main events during the course of disease are activity, remission, relapse, obstruction, fistulizing, surgical resection, cancer and death. Unselected inception cohort studies are the best ones on which rely in order to avoid the selection bias from referral centers. Data produced using inception-cohort have shown a more benign course of CD than expected, an increased risk of surgery over time, with a trend which has been being reduced in the last decades, together with an increased use of biologics…

education.field_of_studymedicine.medical_specialtyCrohn's diseaseColorectal cancerbusiness.industryPopulationLymphoproliferative disordersCancerDiseasemedicine.diseaseInflammatory bowel diseaseInternal medicinemedicineSkin cancerbusinesseducation
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Vulvar involvement in pediatric Crohn’s disease: a systematic review

2018

Purpose: The aim of the study is to report a systematic review (from 2000 to 2017) of all pediatric cases of vulvar Crohn’s disease (VCD) and to highlight the key-points for a correct diagnosis and management of this rare condition. Methods: An electronic search using the Pubmed/Medline, Scopus, EMBASE, Cochrane database and Google Scholar database was performed according to PRISMA guidelines. Results: Twenty pediatric studies and 22 cases of VCD were included for analysis. All the articles reported a single case, except two articles where two cases, respectively, are described. Clinical vulvar examination showed the following main manifestations: vulvar erythema (9/22 cases, 40.9%), vulv…

endocrine systemmedicine.medical_specialtyPediatric Crohn's diseaseVulvar edemaAdministration TopicalAdministration OralDiseasePerineumGastroenterologyVulvaPediatric Crohn’s disease030207 dermatology & venereal diseases03 medical and health sciencesPediatric Crohn’s disease0302 clinical medicineCrohn DiseaseObstetrics and gynaecologyMetronidazoleInternal medicineEdemaHumansMedicineVulvar diseaseChildbusiness.industryObstetrics and GynecologyGeneral MedicineDermatologyExtra-intestinal Crohn’s disease030220 oncology & carcinogenesisVulvar edemaFemaleVulvar DiseasesExtra-intestinal Crohn’s diseasebusinessExtra-intestinal Crohn’s disease; Pediatric Crohn’s disease; Vulvar disease; Vulvar edema; Obstetrics and Gynecology
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Multiplanar and Multiparametric MR Enterography in Crohn’s disease

2015

Learning objectives Background Findings and procedure details Conclusion Personal information References

genetic structuresGastrointestinal tracteducationAbdomenPathologyMRSettore MED/36 - Diagnostica Per Immagini E RadioterapiaSmall bowelContrast agent-intravenousDiagnostic procedureMR Enterography Crohn's disease
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