Search results for "Crypt"

Fungal Biofilms as a Valuable Target for the Discovery of Natural Products That Cope with the Resistance of Medically Important Fungi—Latest Findings

2021

The development of new antifungal agents that target biofilms is an urgent need. Natural products, mainly from the plant kingdom, represent an invaluable source of these entities. The present review provides an update (2017–May 2021) on the available information on essential oils, propolis, extracts from plants, algae, lichens and microorganisms, compounds from different natural sources and nanosystems containing natural products with the capacity to in vitro or in vivo modulate fungal biofilms. The search yielded 42 articles; seven involved essential oils, two Brazilian propolis, six plant extracts and one of each, extracts from lichens and algae/cyanobacteria. Twenty articles deal with th…

In vitro and in vivo anticryptococcal activities of a new pyrazolo-isothiazole derivative

2003

We investigated the activity of a pyrazolo-isothiazole derivative (G8) against Cryptococcus neoformans. A first screening test showed that G8 at 10 mg/L inhibited the growth of 14 of 15 clinical isolates tested. Killing experiments showed that fungicidal activity was achieved after 8 h of treatment with G8 at concentrations > or =10 mg/L. In a murine model of systemic cryptococcosis, G8 was effective at prolonging survival compared with the controls. Our data indicate that this new derivative has a potential therapeutic role in infections caused by C. neoformans.

Phototrophic Fe(II)-oxidation in the chemocline of a ferruginous meromictic lake

2014

Precambrian Banded Iron Formation (BIF) deposition was conventionally attributed to the precipitation of iron-oxides resulting from the abiotic reaction of ferrous iron (Fe(II)) with photosynthetically produced oxygen. Earliest traces of oxygen date from 2.7 Ga, thus raising questions as to what may have caused BIF precipitation before oxygenic photosynthesis evolved. The discovery of anoxygenic phototrophic bacteria thriving through the oxidation of Fe(II) has provided support for a biological origin for some BIFs, but despite reports suggesting that anoxygenic phototrophs may oxidize Fe(II) in the environment, a model ecosystem of an ancient ocean where they are demonstrably active was la…

Epidemiological study ofCryptosporidium parvum in sera of persons from Germany

1998

In a seroprevalence study including 495 sera from persons of all age-groups, the presence of anti-Cryptosporidium parvum antibodies was evaluated in an enzyme immunoassay. Despite the fact that C. parvum is only found in approximately 2% of patients with diarrhea in Germany, specific antibodies could be detected in 15.4% of all samples. This figure indicates that a substantial proportion of the German population has been confronted with this parasite and it raises the question of whether C. parvum is a potential health risk to the general population.

The Role of Lumbar Puncture in the Management of Elevated Intracranial Pressure in Patients with AIDS-Associated Cryptococcal Meningitis

2000

A voice-activated key for the Apple Macintosh computer

1989

An interface circuit to connect a microphone to an Apple Macintosh computer is described. The Apple Macintosh mouse port is used as the input port, and the microphone activation simulates a mouse press.

Healthy Lifestyle, Well-being, Physical Activity, Sport, and Scholastic/academic Performance: Interactions and Connections

2019

The physical activity and sport are key elements for a healthy lifestyle. However, a little-investigated element is the presence of a possible relationship between school or academic performance and the participation in physical activity and sport in groups of preadolescents and adolescents. In order to clarify the complex relationship between mind and body in preadolescence and adolescence, the present discussion investigates the causal and direct relationship between sport activity and performance; and describes how this relationship can be mediated by the sense of self-esteem and self-efficacy; and investigates the relationship between group sports practice and school or academic perform…

An efficient Chinese remainder theorem based node capture resilience scheme for Mobile WSNs

2010

Node capture attack is a critical issue in Mobile WSNs where attacker-controlled replicas may act maliciously. In this paper, we present a novel Chinese remainder theorem based node capture resilience scheme that can be utilized to discover and revoke captured nodes. Moreover, our scheme can limit the ability of captured nodes to further compromise forward security, backward security, and launch collusion attacks. Detailed analysis shows that our scheme indeed achieves the expected design goals.

Formal Analysis and Model Checking of a Group Authentication Protocol by Scyther

2016

Scyther [1] is designed to check the security and vulnerabilities of security protocols. In this paper, we use Scyther to analyze two discrete logarithm problem (DLP) based group authentication protocols proposed in [2]. These two protocols are claimed to satisfy several security requirements, but only part of them have been checked because of the properties and limitations of Scyther. Some positive results have been gained and show that the protocols provide mutual authentication and implicit key authentication and are secure against impersonation attack. An important innovation in this paper is that we have extended the expressing ability of Scyther by giving some reasonable assumption du…

Towards a Formal Analysis of MQtt Protocol in the Context of Communicating Vehicles

2017

International audience; The paper presents a formal approach to model, analyze, and verify a variant of Message Queue Telemetry Transport protocol (MQtt), dedicated to communicating vehicles (MQtt-CV) that send collected data to automotive infrastructures(subscribers). Our formal approach is based on Promela language and its system verification tool, the model checker SPIN. We propose a slight modification of MQtt protocol to reduce the big volume of data collected and sent by vehicles to infrastructures. Indeed, in the original version of MQtt protocol, when a broker receives data from publishers, it sends them directly to its subscribers without any filtration. As consequence, subscribers…