Search results for "Cucurbita"

showing 10 items of 37 documents

An SNP-based saturated genetic map and QTL analysis of fruit-related traits in Zucchini using Genotyping-by-sequencing

2016

[EN] Background: Cucurbita pepo is a cucurbit with growing economic importance worldwide. Zucchini morphotype is the most important within this highly variable species. Recently, transcriptome and Simple Sequence Repeat (SSR)- and Single Nucleotide Polymorphism (SNP)-based medium density maps have been reported, however further genomic tools are needed for efficient molecular breeding in the species. Our objective is to combine currently available complete transcriptomes and the Zucchini genome sequence with high throughput genotyping methods, mapping population development and extensive phenotyping to facilitate the advance of genomic research in this species. Results: We report the Genoty…

0106 biological sciences0301 basic medicineCartographyCandidate geneGenotyping TechniquesPopulationQuantitative Trait LociGenomicsSingle-nucleotide polymorphismFlowersBiologyQuantitative trait locusGBS01 natural sciencesPolymorphism Single NucleotideCandidate genes03 medical and health sciencesCucurbitaGeneticsGens MapatgeeducationGenotyping TechniquesGeneticsMolecular breedingWhole genome sequencingeducation.field_of_studyPigmentationChromosome MappingRILfood and beveragesGenomicsCucurbita pepoGENETICAGenòmica030104 developmental biologyPhenotypePhenotypingFruitSequence Analysis010606 plant biology & botanyBiotechnologyResearch Article
researchProduct

First report of Tomato leaf curl New Delhi virus affecting zucchini squash in an important horticultural area of southern Italy

2016

Tomato leaf curl New Delhi virus (ToLCNDV) is a bipartite begomovirus (family Geminiviridae) which infects species in the families Cucurbitaceae and Solanaceae (Padidam et al., 1995; Mizutani et al., 2011). Begomoviruses are transmitted by the whitefly Bemisia tabaci in a persistent manner (Rosen et al., 2015). In October 2015, severe symptoms not previously reported by growers in the horticultural area of the Province of Trapani (Sicily, Italy) were observed on zucchini squash (Cucurbita pepo) in open fields. The symptoms included yellow mosaic, severe leaf curling, swelling of veins of young leaves, shortening of internodes, roughness of the skin of fruit and reduced fruit size; the sympt…

0106 biological sciences0301 basic medicineHealth Toxicology and MutagenesisTomato leaf curl New Delhi virusPlant Science01 natural sciencesFamily Geminiviridae03 medical and health sciencesBotanyemerging pathogenbiologyBegomovirusfungiSettore AGR/12 - Patologia Vegetalefood and beveragesbiology.organism_classificationbegomovirusCucurbitaceae030104 developmental biologyToLCNDVBipartite begomovirus ToLCNDVAgronomy and Crop ScienceCucurbitaceaeSolanaceae010606 plant biology & botanySquash
researchProduct

Whole-genome resequencing of Cucurbita pepo morphotypes to discover genomic variants associated with morphology and horticulturally valuable traits

2019

[EN] Cucurbita pepo contains two cultivated subspecies, each of which encompasses four fruit-shape morphotypes (cultivar groups). The Pumpkin, Vegetable Marrow, Cocozelle, and Zucchini Groups are of subsp. pepo and the Acorn, Crookneck, Scallop, and Straightneck Groups are of subsp. ovifera. Recently, a de novo assembly of the C. pepo subsp. pepo Zucchini genome was published, providing insights into its evolution. To expand our knowledge of evolutionary processes within C. pepo and to identify variants associated with particular morphotypes, we performed whole-genome resequencing of seven of these eight C. pepo morphotypes. We report for the first time whole-genome resequencing of the four…

0106 biological sciences0301 basic medicineLinkage disequilibriumFruit shapeEvolutionGenomicsPlantesPlant ScienceHorticultureSubspecies01 natural sciencesBiochemistryGenomeArticleCandidate genesStructural variation03 medical and health sciencesCucurbita pepoSizelcsh:BotanyGenetic variationGeneticslcsh:QH301-705.5GeneticsbiologyRevealsSunHomologsbiology.organism_classificationlcsh:QK1-989Common02.- Poner fin al hambre conseguir la seguridad alimentaria y una mejor nutrición y promover la agricultura sostenibleGenòmicaYabby gene familyGENETICA030104 developmental biologyNatural variation in plantslcsh:Biology (General)Genetic markerStructural variation010606 plant biology & botanyBiotechnology
researchProduct

A Major QTL Located in Chromosome 8 of Cucurbita moschata Is Responsible for Resistance to Tomato Leaf Curl New Delhi Virus

2020

[EN] Tomato leaf curl New Delhi virus (ToLCNDV) is a bipartite whitefly transmitted begomovirus, responsible since 2013 of severe damages in cucurbit crops in Southeastern Spain. Zucchini (Cucurbita pepo) is the most affected species, but melon (Cucumis melo) and cucumber (Cucumis sativus) are also highly damaged by the infection. The virus has spread across Mediterranean basin and European countries, and integrated control measures are not being enough to reduce economic losses. The identification of resistance genes is required to develop resistant cultivars. In this assay, we studied the inheritance of the resistance to ToLCNDV previously identified in two Cucurbita moschata accessions. …

0106 biological sciences0301 basic medicineQTLTomato leaf curl New Delhi virusResistanceBOTANICAPlant ScienceBiologylcsh:Plant culture01 natural sciencesSyntenyresistance03 medical and health sciencesCucurbitalcsh:SB1-1110Original ResearchPlantes MalaltiessyntenyZucchinifood and beveragesbiology.organism_classificationzucchiniVirusGENETICA030104 developmental biologyToLCNDVCucurbita moschataHumanities010606 plant biology & botanyFrontiers in Plant Science
researchProduct

Neonicotinoids in excretion product of phloem-feeding insects kill beneficial insects

2019

Significance The use of insecticides in agriculture is one of the suggested causes of the decline in insect populations. Neonicotinoids are among the most widely used insecticides. However, they have important negative side effects, especially for pollinators and other beneficial insects feeding on floral nectar and pollen. We identified an exposure route: Neonicotinoids reach and kill beneficial insects when they feed on the most abundant carbohydrate source for insects in agroecosystems, honeydew. Honeydew is the excretion product of phloem-feeding hemipteran insects such as aphids, mealybugs, whiteflies, or psyllids. This route of exposure is likely to affect a much wider range of benefi…

0106 biological sciencesHoneydewInsectaPhloemBiology010603 evolutionary biology01 natural sciencesBiological control agentsToxicologyNeonicotinoidschemistry.chemical_compoundPollinatorImidaclopridAnimalsNectarBeneficial insectsLaboratory of EntomologyMultidisciplinaryAgricultural Sciencesbusiness.industryPollinatorsfungiNeonicotinoidPest controlfood and beveragesFeeding BehaviorBiological SciencesPE&RCEnvironmental risk assessmentLaboratorium voor EntomologieSurvival AnalysisCucurbitaceae010602 entomologyHoneydewchemistryThiamethoxamEPSbusinessThiamethoxam
researchProduct

Survey of the distribution of Bemisia tabaci (Hemiptera: Aleyrodidae) in Lazio region (Central Italy): a threat for the northward expansion of Tomato…

2018

Bemisia tabaci (Hemiptera: Aleyrodidae) is responsible for severe damage to horticultural and ornamental crops worldwide, mainly for its role as virus vector. In Italy, the B. tabaci Mediterranean (MED) and Middle East–Asia Minor 1 (MEAM1) cryptic species are widespread in the Southern regions as well as in Sicily and Sardinia. During the last two decades, MED populations progressively increased, in those areas where intensive farming is applied. The recent introduction of the begomovirus Tomato leaf curl New Delhi virus (ToLCNDV) prompted extensive surveys of both vector and symptomatic plants. In 2016 and 2017, monitoring activities were carried out in Lazio region (Central Italy) where b…

0106 biological sciencesSpecies complexVeterinary medicinebiologyBegomovirusSettore AGR/12 - Patologia VegetaleOutbreakPlant ScienceWhiteflybiology.organism_classificationWhitefly01 natural sciencesWhitefly MEAM1 species MED species Cucurbitaceae SolanaceaeCucurbitaceae010602 entomologyInsect SciencePlant virusVector (epidemiology)MED speciesMEAM1 speciesLeaf curlGeminiviridaeSolanaceae010606 plant biology & botanyPhytoparasitica
researchProduct

De novoassembly of the zucchini genome reveals a whole-genome duplication associated with the origin of theCucurbitagenus

2018

Summary The Cucurbita genus (squashes, pumpkins and gourds) includes important domesticated species such as C. pepo, C. maxima and C. moschata. In this study, we present a high-quality draft of the zucchini (C. pepo) genome. The assembly has a size of 263 Mb, a scaffold N50 of 1.8 Mb and 34 240 gene models. It includes 92% of the conserved BUSCO core gene set, and it is estimated to cover 93.0% of the genome. The genome is organized in 20 pseudomolecules that represent 81.4% of the assembly, and it is integrated with a genetic map of 7718 SNPs. Despite the small genome size, three independent lines of evidence support that the C. pepo genome is the result of a whole-genome duplication: the …

0301 basic medicineSequence assemblyPlant ScienceBiologyBiotecnologiaGenome03 medical and health sciencesCucurbitaGene DuplicationGene duplicationGene familycropCucurbitagenomeGenome sizeGeneCitrullusResearch Articlesbiology.organism_classificationBiological EvolutionzucchiniCucurbitaceaeGenòmica030104 developmental biologyEvolutionary biologywhole‐genome duplicationTranscriptomeAgronomy and Crop ScienceGenome PlantResearch ArticleBiotechnologyPlant Biotechnology Journal
researchProduct

Nutritional characterization of Butternut squash (Cucurbita moschata D.): Effect of variety (Ariel vs. Pluto) and farming type (conventional vs. orga…

2019

Farming systems and cultivar types are two of the main factors able to affect the nutritional quality of plant foods for human nutrition. Therefore, the aim of this study was to compare the impact of two unexplored variety (namely Ariel and Pluto) and farming type (conventional and organic) on physicochemical parameters, chemical and mineral composition, water- and fat-soluble vitamins, amino acid profile and antioxidant bioactive components of butternut squashes (Cucurbita moschata). In order to achieve this purpose, a multivariate statistical discrimination of the different parameters was carried out using the unsupervised principle component analysis (PCA). The most important differences…

030309 nutrition & dieteticsPhytochemicalsAntioxidants03 medical and health sciencesAntioxidant activity; Conventional-cultivars; Cucurbitaceae; Organic-cultivars; Phytochemicals0404 agricultural biotechnologyAntioxidant activityCucurbitaSettore AGR/13 - CHIMICA AGRARIAHumansNutsMagnesiumCultivarTocopherolFood scienceManganeseMinerals0303 health sciencesPlutobiologyChemistryOrganic-cultivarsSodiumConventional-cultivarsfood and beveragesAgriculture04 agricultural and veterinary sciencesbeta Carotenebiology.organism_classification040401 food scienceCucurbitaceaeZincHuman nutritionCucurbita moschataPotassiumOrganic farmingComposition (visual arts)Nutritive ValueCucurbitaceaeFood ScienceSquashFood Research International
researchProduct

Cytotoxicity of cucurbitacin E from Citrullus colocynthis against multidrug-resistant cancer cells

2019

Abstract Background Cucurbitacin E (CuE) is an oxygenated tetracyclic triterpenoid isolated from the fruits of Citrullus colocynthis (L.) Schrad. Purpose This study outlines CuE's cytotoxic activity against drug-resistant tumor cell lines. Three members of ABC transporters superfamily, P-glycoprotein (P-gp), breast cancer resistance protein (BCRP) and ABCB5 were investigated, whose overexpression in tumors is tightly linked to multidrug resistance. Further factors of drug resistance studied were the tumor suppressor TP53 and the epidermal growth factor receptor (EGFR). Methods Cytotoxicity assays (resazurin assays) were used to investigate the activity of Citrullus colocynthis and CuE towar…

Abcg2Drug ResistancePharmaceutical ScienceATP-binding cassette transporterMicroarraySubfamily Gchemistry.chemical_compoundGene Knockout Techniques0302 clinical medicineEpidermal growth factorPhytogenicDrug DiscoveryATP Binding Cassette Transporter Subfamily G Member 2Cancer0303 health sciencesTumorLeukemiabiologyChemistryABCB5TransfectionCell cycleNeoplasm ProteinsGene Expression Regulation NeoplasticErbB ReceptorsMolecular Docking SimulationSubfamily B030220 oncology & carcinogenesisMolecular MedicineCitrullus colocynthiMember 2Member 1ATP Binding Cassette Transporter Subfamily BATP Binding Cassette TransporterAntineoplastic AgentsCell Line03 medical and health sciencesCell Line TumorHumansATP Binding Cassette Transporter Subfamily B Member 1030304 developmental biologyCucurbitacin EPharmacologyNeoplasticTraditional herbal medicineCancer; Citrullus colocynthis; Drug resistance; Microarray; Traditional herbal medicine; ATP Binding Cassette Transporter Subfamily B; ATP Binding Cassette Transporter Subfamily B Member 1; ATP Binding Cassette Transporter Subfamily G Member 2; Antineoplastic Agents Phytogenic; Cell Line Tumor; Citrullus colocynthis; Doxorubicin; Drug Resistance Neoplasm; ErbB Receptors; Gene Expression Regulation Neoplastic; Gene Knockout Techniques; Humans; Leukemia; Molecular Docking Simulation; Neoplasm Proteins; Triterpenes; Tumor Suppressor Protein p53Antineoplastic Agents PhytogenicTriterpenesComplementary and alternative medicineGene Expression RegulationDrug Resistance NeoplasmDoxorubicinCancer cellbiology.proteinCancer researchNeoplasmCitrullus colocynthisTumor Suppressor Protein p53
researchProduct

Mitochondrial transcriptional study of the effect of aflatoxins, enniatins and carotenoids in vitro in a blood brain barrier model

2020

C. maxima (var. Delica), a variety of pumpkin, is well known for its high concentration on carotenoids, possessing dietary benefits and antioxidant properties. Aflatoxins and enniatins are common mycotoxins present in food and feed with an extended toxicity profile in humans and animals. Both types of substances reach a wide range of tissues and organs and have the capability to penetrate the blood brain barrier. Since carotenoids and mycotoxins have been reported to modify diverse mitochondrial processes individually, transcriptional in vitro studies on human epithelial cells ECV 304 were conducted to analyze the relative expression of 13 mitochondria related genes. ECV 304 cells were diff…

AflatoxinMitochondrial DNAAntioxidantmedicine.medical_treatmentAlzheimer Antioxidants Mycotoxicity Neurodegenerative diseases Carotenoids qPCR ECV 304MitochondrionToxicologyBlood–brain barrierAntioxidantsCell LineNOchemistry.chemical_compoundAflatoxinsCucurbitaDepsipeptidesHuman Umbilical Vein Endothelial CellsmedicineHumansECV 304MycotoxinMycotoxicityCarotenoidchemistry.chemical_classificationLS9_6Neurodegenerative diseasesfood and beveragesGeneral MedicineCarotenoidsIn vitroMitochondriaqPCRmedicine.anatomical_structureElectron Transport Chain Complex ProteinschemistryBiochemistryBlood-Brain BarrierAlzheimerFood Science
researchProduct