Search results for "Cutaneous"

showing 10 items of 1022 documents

Effect of Coronary Disease Characteristics on Prognostic Relevance of Residual Ischemia After Stent Implantation

2021

Objectives: We investigated the influence of coronary disease characteristics on prognostic implications of residual ischemia after coronary stent implantation.Methods: This study included 1,476 patients with drug-eluting stent implantation and available pre- and post-percutaneous coronary intervention (PCI) fractional flow reserve (FFR) measurements. Residual ischemia was defined as post-PCI FFR ≤ 0.80. Coronary disease characteristics with significant interaction hazard ratios (HRs) for clinical outcomes with residual ischemia were defined as interaction characteristics with residual ischemia (ICwRI). The primary outcome was target vessel failure (TVF)—a composite of cardiac death, target…

RC666-701percutaneous coronary interventionDiseases of the circulatory (Cardiovascular) systemcardiovascular diseasesCardiovascular Medicineatherosclerosisresidual ischemiafractional flow reserveCardiology and Cardiovascular Medicinecoronary artery diseaseOriginal ResearchFrontiers in Cardiovascular Medicine
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Curative therapies for hepatocellular carcinoma: an update and perspectives.

2015

Curative treatments, including liver transplantation, surgical resection and percutaneous treatments, are the recommended therapies in BCLC-0 (Barcelona Clinic of Liver Cancer) or BCLC-A hepatocellular carcinoma (HCC). This review provides an overview of some issues of clinical importance concerning curative treatments in HCC.

RFASurgical resectionAblation TechniquesPathologymedicine.medical_specialtyPercutaneousCarcinoma HepatocellularAblative therapymedicine.medical_treatmentLiver transplantationResection03 medical and health sciences0302 clinical medicinemedicineHepatectomyHumansPharmacology (medical)resectionHCCAblative therapy; early stage; HCC; liver transplant; PEI; resection; RFA; Ablation Techniques; Carcinoma Hepatocellular; Hepatectomy; Humans; Liver Neoplasms; Liver Transplantation; Oncology; Pharmacology (medical)business.industryCarcinomaLiver NeoplasmsHepatocellularearly stagemedicine.diseasedigestive system diseasesPEISurgeryLiver Transplantationliver transplantOncology030220 oncology & carcinogenesisHepatocellular carcinoma030211 gastroenterology & hepatologyLiver cancerbusinessExpert review of anticancer therapy
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Radiofrequency thermal ablation vs percutaneous ethanol injection for small hcc in cirrhosis:metanalysis of randomized controlled trials

2009

1. Am J Gastroenterol. 2009 Feb;104(2):514-24. Epub 2009 Jan 13. Radiofrequency thermal ablation vs. percutaneous ethanol injection for small hepatocellular carcinoma in cirrhosis: meta-analysis of randomized controlled trials. Orlando A, Leandro G, Olivo M, Andriulli A, Cottone M. Department of Medicine, Pneumology and Nutrition Clinic, V. Cervello Hospital, University of Palermo, Piazza Mameli 1, Palermo, Italy. ambrogiorlando@tiscali.it OBJECTIVES: Radiofrequency thermal ablation (RF) and percutaneous ethanol injection (PEI) have been employed in the treatment of small hepatocellular carcinoma (HCC) as curative treatments. The aim of the study was to review the available evidence compari…

Radiofrequency thermal ablation percutaneous ethanol injecction small hepatocellular carcinoma meta-analysis
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[Percutaneous vertebroplasty]

2003

RadiographyFractures SpontaneousBack PainBone CementsHumansMinimally Invasive Surgical ProceduresOsteoporosisPolymethyl MethacrylateSpinal FracturesPercutaneous vertebroplastyInjections Spinal
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The foot fillet flap for ischial pressure sore reconstruction: A new indication

2018

Abstract Introduction The main cause of ischial pressure sores in paraplegic patients is prolonged sitting without pressure relief. These wounds are subject to recurrence and may need repeated reconstruction with local flaps. When all options are exhausted, the total thigh flap is the last resort. Disarticulation of the hip joint impairs stability even when sitting and causes subsequently very high discomfort. In this manuscript, we describe an alternative to the total thigh flap to avoid hip disarticulation: the foot fillet flap. Materials & Methods This study was performed on four patients at the department of Plastic & Reconstructive Surgery of the Ghent University Hospital, Belgium. Inc…

Reconstructive surgerymedicine.medical_specialtyDisarticulationPressure soresSettore MED/19 - Chirurgia Plastica030230 surgerySitting01 natural sciencesSurgical Flaps010309 optics03 medical and health sciences0302 clinical medicineIschiumRecurrence0103 physical sciencesmedicineReconstructive Surgical ProcedureHumansSurgical FlapsFillet (mechanics)Pressure UlcerFootbusiness.industryPlastic Surgery Proceduresmedicine.diseaseIschiumSurgeryTreatment Outcomemedicine.anatomical_structureSurgerybusinessHumanSubcutaneous tissueJournal of Plastic, Reconstructive & Aesthetic Surgery
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Electrochemotherapy for advanced cutaneous angiosarcoma: A European register-based cohort study from the International Network for Sharing Practices …

2019

Abstract Background Cutaneous angiosarcoma (cAS) is a highly aggressive malignancy that challenges the radicality of surgical treatment. Electrochemotherapy (ECT), a skin-directed treatment based on cytotoxic chemotherapy combined with local electric pulses, may be an intraoperative adjunct and a new opportunity in the therapeutic strategy. This cohort study reports the experience with ECT as an option. Methods Data on patients with locally-advanced/metastatic cAS who underwent ECT between October 2013 and October 2018 at eight European centres were prospectively submitted to the InspECT (International network for sharing practices of ECT) register. Patients received therapy according to th…

Register basedmedicine.medical_specialtyElectrochemotherapySkin NeoplasmsElectrochemotherapyHemangiosarcomaSkin metastasesTumour controlPainKaplan-Meier EstimateMalignancyCutaneous angiosarcomaCohort Studies03 medical and health sciencesBleomycin0302 clinical medicineAntibioticsSkin Ulcermedicine80 and overHumansAngiosarcomaCutaneous angiosarcoma; Electrochemotherapy; Skin metastases; Skin-directed therapies; Tumour control; Aged; Aged 80 and over; Antibiotics Antineoplastic; Bleomycin; Cohort Studies; Electrochemotherapy; Feasibility Studies; Female; Hemangiosarcoma; Humans; Kaplan-Meier Estimate; Middle Aged; Pain; Patient Reported Outcome Measures; Prospective Studies; Registries; Skin Neoplasms; Skin Ulcer; Treatment OutcomePatient Reported Outcome MeasuresProspective StudiesRegistriesSkin-directed therapiesAgedAged 80 and overInternational networkAntibiotics Antineoplasticbusiness.industryGeneral MedicineMiddle Agedmedicine.diseaseAntineoplasticmedicine.anatomical_structureTreatment OutcomeTolerability030220 oncology & carcinogenesisScalpFeasibility Studies030211 gastroenterology & hepatologySurgeryFemaleRadiologybusinessCohort studyInternational journal of surgery (London, England)
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COVID-19 pandemic, mechanical reperfusion and 30-day mortality in ST elevation myocardial infarction

2022

ObjectiveThe initial data of the International Study on Acute Coronary Syndromes - ST Elevation Myocardial Infarction COVID-19 showed in Europe a remarkable reduction in primary percutaneous coronary intervention procedures and higher in-hospital mortality during the initial phase of the pandemic as compared with the prepandemic period. The aim of the current study was to provide the final results of the registry, subsequently extended outside Europe with a larger inclusion period (up to June 2020) and longer follow-up (up to 30 days).MethodsThis is a retrospective multicentre registry in 109 high-volume primary percutaneous coronary intervention (PPCI) centres from Europe, Latin America, S…

RegistrieMaleST Elevation Myocardial Infarction/diagnosisTime FactorsPercutaneousmedicine.medical_treatmentVascular damage Radboud Institute for Health Sciences [Radboudumc 16]Coronary Artery DiseasePractice Patterns030204 cardiovascular system & hematologyRate ratioTime-to-Treatment/trendsCardiologists0302 clinical medicineRetrospective StudieHeart RateRisk FactorsPandemicST segmentRegistriesHospital Mortality030212 general & internal medicineMyocardial infarctionPractice Patterns Physicians'10. No inequalityPercutaneous Coronary Intervention/adverse effectsHospital Mortality/trendsCOVID-19; myocardial infarction; percutaneous coronary interventionIncidenceIncidence (epidemiology)*percutaneous coronary interventionMiddle Aged3. Good healthTreatment Outcomemyocardial infarctionCardiologyFemale*COVID-19Cardiology and Cardiovascular MedicineCardiologists/trendsHumanCOVID-19; myocardial infarction; percutaneous coronary intervention; Aged; Cardiologists; Female; Hospital Mortality; Humans; Incidence; Male; Middle Aged; Percutaneous Coronary Intervention; Practice Patterns Physicians'; Registries; Retrospective Studies; Risk Assessment; Risk Factors; ST Elevation Myocardial Infarction; Time Factors; Time-to-Treatment; Treatment Outcome; COVID-19medicine.medical_specialtyTime FactorCoronavirus disease 2019 (COVID-19)CardiologistRisk AssessmentTime-to-Treatment03 medical and health sciencesInternal medicinemedicineHumansAcute Coronary SyndromePandemicsRetrospective StudiesAgedPhysicians'SARS-CoV-2business.industryRisk FactorCOVID-19 myocardial infarction percutaneous coronary interventionpercutaneous coronary interventionPercutaneous coronary interventionCOVID-19*myocardial infarctionmedicine.diseasePractice Patterns Physicians'/trendsST Elevation Myocardial Infarctionbusiness
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Immunopathology of leishmaniasis: an update.

2007

Leishmaniasis represents a severe, increasing, public health problem. The perspective of its control is highly dependent on research progress, on therapeutic manipulations of the immune system, and on vaccine development. There is a correlation between the clinical outcome of Leishmania infection and the cytokine response profile. While a protective immune response against Leishmania has been clearly identified to be related to the influence of a type-1 response and IFN-γ production, the precise role of T helper (TH) 2 cytokines in non-healing infections requires further exploration. IL-4 and IL-13 (TH2 cytokines) can promote disease progression in cutaneous leishmaniasis, whereas IL-4 woul…

Regulatory T cellImmunopathology; LeishmaniasisengT-LymphocytesImmunologyApoptosisImmunopathology03 medical and health sciences0302 clinical medicineImmune systemCutaneous leishmaniasisImmunopathologyLeishmaniasisengmedicineImmunology and AllergyAnimalsHumansLeishmaniasisPharmacologybiologybusiness.industryLeishmaniasismedicine.diseaseLeishmaniabiology.organism_classificationmedicine.anatomical_structureVisceral leishmaniasis030220 oncology & carcinogenesisImmunologybusinessCD8030215 immunologyInternational journal of immunopathology and pharmacology
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Endoluminal Stent-Graft Relining of Visceral Artery Bypass Grafts to Treat Perigraft Seroma

2013

PURPOSE: To describe the endovascular treatment of intra-abdominal perigraft seromas associated with small-caliber expanded polytetrafluoroethylene (ePTFE) grafts. CASE REPORTS: Two patients who underwent hybrid repair of thoracoabdominal aortic aneurysms in which renovisceral bypass grafts were implanted presented with large, symptomatic perigraft seromas. The 5- to 8-mm-diameter ePTFE bypass grafts believed to be involved in the seromas were successfully relined with self-expanding Viabahn stent-grafts in percutaneous procedures. The patients' symptoms were relieved, and imaging follow-up (18 and 10 months, respectively) has shown near complete resorption of the seromas. CONCLUSION: It is…

Reoperationmedicine.medical_specialtyAortographyPercutaneous610 Medicine & healthProsthesis DesignAortography2705 Cardiology and Cardiovascular MedicineBlood Vessel Prosthesis ImplantationAortic aneurysmBlood vessel prosthesismedicinePerigraft seromaHumans2741 Radiology Nuclear Medicine and ImagingRadiology Nuclear Medicine and imagingPolytetrafluoroethyleneAortic Aneurysm Thoracicmedicine.diagnostic_testbusiness.industryEndovascular ProceduresMiddle Agedmedicine.diseaseBlood Vessel Prosthesis10020 Clinic for Cardiac Surgery2746 SurgerySurgerybody regionsVisceraSeromaTreatment Outcomesurgical procedures operativeBypass surgeryCardiothoracic surgerySeromaFemaleStentsSurgeryRadiologyTomography X-Ray ComputedCardiology and Cardiovascular MedicinebusinessJournal of Endovascular Therapy
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Procedural characteristics and outcomes following chronic total occlusion coronary intervention: pooled analysis from 5 registries.

2021

Background Recent improvement in clinical skills, technology and hardware has resulted in improved success rates with chronic total occlusion (CTO) percutaneous coronary intervention (PCI). We performed a study level pooled analysis from the five largest registries of percutaneous coronary intervention (PCI) of CTO. Research design and methods We conducted pooled analysis of 9500 patients in registries and data on procedural characteristics, technical success, and MACCE was collected. Results A total of 9500 patients were included in the analysis. Mean age was 65.4 years with previous CABG in 24.8%, reattempt procedure in 24.8% and mean JCTO score was 2.2. Final wiring strategy in hybrid al…

Research designmedicine.medical_specialtymedicine.medical_treatmentCoronary AngiographyTotal occlusionPercutaneous Coronary InterventionRisk FactorsCardiac tamponadeInternal medicineInternal MedicineMedicineHumansRegistriesStrokeAgedbusiness.industryPercutaneous coronary interventionGeneral Medicinemedicine.diseasePooled analysisTreatment OutcomeCoronary OcclusionConventional PCIChronic DiseaseCardiology and Cardiovascular MedicinebusinessComplicationExpert review of cardiovascular therapy
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