Search results for "Cyclodextrin"
showing 10 items of 266 documents
Silica Materials Containing Cyclodextrin for Pollutant Removal
2018
This chapter reviews the use of cyclodextrin-silica hybrid systems and cyclodextrin-functionalized silica used as adsorbents or filters for the removal of inorganic and organic pollutants from aqueous solutions in solid-phase extraction and adsorption-oriented processes. Actually, there is a need to develop efficient processes for the synthesis and application of multifunctional silica-based materials for pollutant removal by adsorption or filtration, and for sample purification and concentration using solid-phase extraction.
Scopolamine Derivatives as Potential Pharmaceuticals with Calixarene-CyclodextrineNanosponges as Drug Carriers
2017
Tropane alkaloids are molecules with a strong biological activity, which are mainly produced by the members offamily Solanaceae, but also found inother plant families (Convolvulaceae, Brasicaceae, Erythroxylaceae andEuphorbiaceae).1 More than 20 active pharmaceutical substances containingthetropane moiety have been industrially produced and applied as mydriatics, antiemetics, antispasmodics, anesthetics and bronchodilators.Nearly all of them are based on the Scopolamine structure.2 In recent years, several researchers aimed their work to the use of supramolecular systems for the inclusion of organic species, such as complex systems based on cyclodextrines or calixarenes.3They have attracted…
Acid-base properties and sequestering abilities towards toxic metal ions of cyclodextrin-calixarene co-polymers
Smart materials with stimuli-responsive properties represent an interesting research area considering both their potential applications and the conceptual issues implied. They might be successfully employed in various fields, such as drug carrier/delivery devices to sensors, environment remediation, active packaging [1-2]. In this contest, we have recently synthesized various pH-responsive pre- and post-modified cyclodextrin-calixarene nanosponges (CyCaNSs) with 1,2,3-triazole linker units (ACNSs) able to vary their sequestering abilities towards organic and inorganic compounds. In particular, their adsorption properties were varied changing the molar ratio between the co-monomers, and the …
Complexes of amphiphilic cyclodextrins and tributiltin(IV) porphyrin derivatives as potential nanotherapeutics against melanoma.
2013
Porphyrin tributyltin(IV) complexes for a novel approach in the tratment of human melanoma
2012
Melanoma is the most deadly form of skin cancer, largely refractory to existing therapies. The study of porphyrin derivatives as potential anti-tumor drugs has been an interesting field of investigation in the last years. Recently, a photo-independent cytotoxic effect of (Bu3Sn)4TPPS in the blocking melanoma cell proliferation an inducing a morphology cell change was investigated.[1] Amphiphilic CD (ACyD) provides more water soluble and adaptable nanovectors through modulation of the balance between hydrophobic and hydrophilic chains at both CD sides. ACyD can be conveniently tailored by covalently appending fluorescent label or receptor-targeting glycosyl- groups and can encapsulate conven…