Search results for "Cyst"

showing 10 items of 1960 documents

A case report of coexistence of a sialolith and an adenoid cystic carcinoma in the submandibular gland

2006

Ôhe occurrence of sialoliths in the submandibular gland is 80% due to the specific anatomy of both the gland and its duct. The diagnosis is rather easy because of the obvious clinical signs of the entity. Imaging studies are always necessary in order to treat the patient as effectively as possible. The stones do not tend to occur within the gland as frequently as in the respective duct. The coexistence of sialoliths and malignant tumors is extremely rare. A 70-year-old woman with intraparenchymal stone was operated in our ENT department. In addition to the sialolith the pathological examination revealed the existence of an adenoid cystic carcinoma (ACC), that extended to the neighboring ske…

stomatognathic systemsubmandibular glandUNESCO::CIENCIAS MÉDICASadenoid cystic carcinomaSialolithiasis:CIENCIAS MÉDICAS [UNESCO]
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CISTOADENOMA GIGANTE DELL'OVAIO: CONSIDERAZIONI CLINICHE E STRATEGIA DIAGNOSTICA

2004

gli autori riortano il caso di una donna obesa affetta da cistoadenoma mucinoso gigante dell'ovaio. nonostante la presenza di una massa addominale voluminosa, la paziente non accusava sintomatologia degna di rilievo.

the authors report a case of an adult fat woman presenting giant cystadenoma of the ovary. she was asymptomatics for a long time and thepresence of a giant ovarian cyst was masked by obesity.
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Modified Glasgow Prognostic Score is Associated With Risk of Recurrence in Bladder Cancer Patients After Radical Cystectomy

2015

Recently, many studies explored the role of inflammation parameters in the prognosis of urinary cancers, but the results were not consistent. The modified Glasgow Prognostic Score (mGPS), a systemic inflammation marker, is a prognostic marker in various types of cancers. The aim of the present study was to investigate the usefulness of the preoperative mGPS as predictor of recurrence-free (RFS), overall (OS), and cancer-specific (CSS) survivals in a large cohort of urothelial bladder cancer (UBC) patients.A total of 1037 patients with UBC were included in this study with a median follow-up of 22 months (range 3-60 months). An mGPS = 0 was observed in 646 patients (62.3%), mGPS = 1 in 297 pa…

to-lymphocyte ratioAdultMaleRiskmedicine.medical_specialtyPrognosimedicine.medical_treatmentCystectomyGastroenterologySettore MED/24 - UrologiaCystectomyMedicine (all); c-reactive protein; advanced urothelial carcinoma; to-lymphocyte ratioc-reactive proteinRetrospective StudieInternal medicine80 and overHumansMedicineStage (cooking)advanced urothelial carcinomaRetrospective StudiesAgedAged 80 and overModified Glasgow Prognostic Score is Associated With Risk of Recurrence in Bladder Cancer Patients After Radical Cystectomy: A Multicenter Experience.Univariate analysisBladder cancerbusiness.industryProportional hazards modelMedicine (all)Hazard ratioBladder cancer Radical cystectomyRetrospective cohort studyGeneral MedicineMiddle AgedPrognosismedicine.diseaseSurgeryNeoplasm RecurrenceLocalUrinary Bladder NeoplasmsUrinary Bladder NeoplasmCohortFemaleNeoplasm Recurrence LocalAdult; Aged; Aged 80 and over; Female; Humans; Male; Middle Aged; Neoplasm Recurrence Local; Prognosis; Retrospective Studies; Risk; Urinary Bladder Neoplasms; Cystectomy; Medicine (all)businessHumanMedicine
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Images - Computed tomography urographic appearance of traumatic rupture of renal cyst into the pyelocaliceal system.

2019

Spontaneous or traumatic rupture of renal cysts, documented by radiological imaging, occurs infrequently. The pathogenesis of a cyst rupture is still unclear, except when it has occurred following trauma or when the cyst has become infected. Imaging plays a crucial role in the diagnosis, management, surveillance, and choice of lesions that need treatment.

traumatic rupturemedicine.medical_specialtyKidneymedicine.diagnostic_testbusiness.industryUrologyComputed tomographymedicine.diseaseImages in UrologySettore MED/24 - Urologiarenal cystimagin.Cystic kidney diseasemedicine.anatomical_structureOncologymedicineCystRadiologySettore MED/36 - Diagnostica Per Immagini E RadioterapiabusinessCanadian Urological Association journal = Journal de l'Association des urologues du Canada
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Dipeptidyl Enoates As Potent Rhodesain Inhibitors That Display a Dual Mode of Action

2015

Dipeptidyl enoates were prepared through a high-yielding two-step synthetic route. They have a dipeptidic structure with a 4-oxoenoate moiety as a warhead with multiple reactive sites. Dipeptidyl enoates were screened against rhodesain and human cathepsins B and L, and were found to be potent and selective inhibitors of rhodesain. Among them (S,E)-ethyl 5-((S)-2-{[(benzyloxy)carbonyl]amino}-3-phenylpropanamido)-7-methyl-4-oxooct-2-enoate (6) was the most potent, with an IC50 value of 16.4 nm and kinact/Ki=1.6×106 m−1 s−1 against rhodesain. These dipeptidyl enoates display a reversible mode of inhibition at very low concentrations and an irreversible mode at higher concentrations. Inhibition…

trypanosomiasisStereochemistrysleeping sicknessCathepsin LDrug Evaluation PreclinicalChemistry Techniques SyntheticInhibition kineticsCysteine Proteinase InhibitorsBiochemistryCathepsin BInhibitory Concentration 50Structure-Activity RelationshipinhibitorsDrug DiscoveryHumansMoietyMolecular Targeted TherapyGeneral Pharmacology Toxicology and PharmaceuticsIC50Volume concentrationrhodesainPharmacologyChemistryOrganic ChemistryDual modeDipeptidesTrypanocidal AgentsCombinatorial chemistryMolecular Docking SimulationCysteine EndopeptidasesKineticsdipeptidyl enoatesTrypanosomiasis AfricanDocking (molecular)Molecular MedicineCysteine thiolateChemMedChem
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Carcinoma Primario Intraóseo y quiste odontogénico: Tres casos clínicos y revisión de la Literatura

2006

Introducción: Los Carcinomas Intraóseos Primarios Odontogénicos (PIOC) son un raro grupo de tumores malignos con unos estrictos criterios diagnósticos clínicos y anatomo-patológicos. Las diferentes clasificaciones sugeridas para estos tumores y el escaso número de casos descritos en la literatura hacen difícil conocer con exactitud cuantos son los casos reales publicados hasta el día de hoy. Material y métodos: presentamos tres nuevos casos de PIOC originados a partir de una lesión quística previa que fueron tratados en nuestro centro. Dos en región posterior mandibular que es el lugar de más frecuente aparición, y un tercero en maxilar superior. Explicamos el tipo de cirugía llevado a cabo…

tumor odontógenoCarcinoma intraóseo primarioPrimary intraosseous carcinomaUNESCO::CIENCIAS MÉDICASquiste maxilarodontogenic tumourjaw cyst:CIENCIAS MÉDICAS [UNESCO]
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TENSION FREE CYSTOCELE REPAIR. FOUR YEARS FOLLOW-UP

2003

Aims of study: Anterior vaginal wall descensus is one of the most frequent alteration in patients with pelvic defects. At least 50% of women that had delivered two or more times presented a certain degree of this pathologic alteration of the anatomy, even thought only 10-20% of the patients complained of associated pains. The use of synthetic biocompatible materials has become more common in gynecology surgery(1)-(3). Polypropylene mesh to be proposed as a mean of surgical correction of moderate severe cystocele (Cervigni 1998)(2) Methods: 97 patients aged 42-75, parity 1-5, body weight 45-90, menopause 41 pts. (61%).Irritative sintoms( nocturia, frequency, urgency, dysuria and urge inconti…

vaginal wall descensus TENSION FREE CYSTOCELE REPAIR pelvic defectsSettore MED/40 - Ginecologia E Ostetricia
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Papillomavirus assembly requires trimerization of the major capsid protein by disulfides between two highly conserved cysteines.

1998

ABSTRACT We have used viruslike particles (VLPs) of human papillomaviruses to study the structure and assembly of the viral capsid. We demonstrate that mutation of either of two highly conserved cysteines of the major capsid protein L1 to serine completely prevents the assembly of VLPs but not of capsomers, whereas mutation of all other cysteines leaves VLP assembly unaffected. These two cysteines form intercapsomeric disulfides yielding an L1 trimer. Trimerization comprises about half of the L1 molecules in VLPs but all L1 molecules in complete virions. We suggest that trimerization of L1 is indispensable for the stabilization of intercapsomeric contacts in papillomavirus capsids.

virusesImmunologyTrimerBiologymedicine.disease_causeMicrobiologycomplex mixturesSerineCapsidVirologyAnimal VirusesmedicineCysteineDisulfidesPapillomaviridaeMutationVirus AssemblyCapsomereVirionvirus diseasesbiochemical phenomena metabolism and nutritionMolecular biologyCapsidInsect ScienceMutationBiophysicsCysteineJournal of virology
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Listy otwarte Jędrzeja Giertycha do społeczeństwa w kraju z 1976 i 1982 r

2020

Jędrzej Giertych, niezwykle płodny publicysta i ideolog mchu narodowego na emigracji, w 1976 i 1982 r. ogłosił listy otwarte do społeczeństwa w kraju. Listy pisane w okresie narastania niepokojów społecznych i perturbacji politycznych w PRL były swoistym narzędziem walki politycznej oraz komunikacji z rodakami w kraju. Do zabrania głosu skłaniała Giertycha troska o los Polski. Emigracyjny publicysta czuł moralną potrzebę mówienia do narodu. W tonie żarliwego patriotyzmu ostrzegał przed groźbą antysowieckiego powstania, demaskował knowania światowego żydostwa, odwoływał się do straszaka niemieckiego. Wiemy spiskowej teorii dziejów, odsłaniał „prawdziwe” oblicze „trockistów” oraz piłsudczyków…

wywiad PRLWojciech Jaruzelskistan wojenny w Polsceopozycja polityczna w PRLJędrzej GiertychAdam MichnikStefan Michnikpublicystyka polska na emigracji
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Iedzīvotāju zināšanas par žultsakmeņu slimības attīstību veicinošajiem faktoriem un profilaksi

2021

Visā pasaulē, tajā skaitā arī Latvijā, viena no biežākajām ķirurģiskajām saslimšanām, kam nepieciešama operatīva ārstēšana, ir žultsakmeņu slimība (ŽAS) jeb holelitāze. Tās izplatība pieaug līdz ar iedzīvotāju vecumu un mūsdienu dzīvesveida paradumiem, tādiem kā, nesabalansēts, neregulārs uzturs un mazkustīgs dzīvesveids. Šis bakalaura darbs tika izveidots ar mērķi - noskaidrot iedzīvotāju zināšanas par žultsakmeņu slimības attīstību veicinošajiem faktoriem un profilaksi. Pirms pētījuma veikšanas, lai pārliecinātos par anketas jautājumu saprotamību, tika veikts pilotpētījums, aptaujājot desmit respondentus. Analizējot, sniegtās atbildes, tika secināts, ka ir nepieciešams veikt labojumus 4. …

žultsakmeņu slimībalaparaskopiska holecistektomijacholelithiasislaparoscopic cholecystectomyMedicīnaiedzīvotāju zināšanas
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