Search results for "D1"
showing 10 items of 3056 documents
Rugged Large Volume Injection for Sensitive Capillary LC-MS Environmental Monitoring
2017
A rugged and high throughput capillary column (cLC) LC-MS switching platform using large volume injection and on-line automatic filtration and filter back-flush (AFFL) solid phase extraction (SPE) for analysis of environmental water samples with minimal sample preparation is presented. Although narrow columns and on-line sample preparation are used in the platform, high ruggedness is achieved e.g. injection of 100 non-filtrated water samples would did not result in a pressure rise/clogging of the SPE/capillary columns (inner diameter 300 µm). In addition, satisfactory retention time stability and chromatographic resolution were also features of the system. The potential of the platform for …
CD14+CD16+ monocytes in coronary artery disease and their relationship to serum TNF-α levels
2004
SummaryMonocytes play a central role in the inflammatory disease atherosclerosis. CD14+CD16+ monocytes are considered proinflammatory monocytes, as they have an increased capacity to produce proinflammatory cytokines, such as TNF-α, and are elevated in various inflammatory diseases. We hypothesized that patients with coronary artery disease (CAD) have increased levels of CD14+CD16+ monocytes, and that CD14+CD16+ monocytes are associated with inflammation markers. We investigated CD14+CD16+ monocytes in 247 patients with CAD and 61 control subjects using flow cytometry. In addition serum concentrations of TNF-α, IL-6, and Hs-CRP were assessed. Patients with CAD had higher levels of CD14+CD16…
Biochemical and Immunological implications of Lutein and Zeaxanthin
2021
Throughout history, nature has been acknowledged for being a primordial source of various bioactive molecules in which human macular carotenoids are gaining significant attention. Among 750 natural carotenoids, lutein, zeaxanthin and their oxidative metabolites are selectively accumulated in the macular region of living beings. Due to their vast applications in food, feed, pharmaceutical and nutraceuticals industries, the global market of lutein and zeaxanthin is continuously expanding but chemical synthesis, extraction and purification of these compounds from their natural repertoire e.g., plants, is somewhat costly and technically challenging. In this regard microbial as well as microalga…
Análisis poblacional y filogeográfico de vectores de la enfermedad de Chagas en Perú basado en análisis multigénicos del ADN ribosomal y mitocondrial
2017
La enfermedad de Chagas, cuyo agente causal es Trypanosoma cruzi, constituye un grave problema de salud pública en toda Latinoamérica. La principal forma de transmisión es la vectorial, de la que son responsables hemípteros redúvidos de la subfamilia Triatominae adaptados a los hábitats doméstico y peridoméstico. Puesto que el parásito se mantiene en un ciclo zoonótico silvestre y es imposible de eliminar, la principal forma de lucha contra la transmisión vectorial consiste en la eliminación de las poblaciones domiciliadas del vector. Los estudios moleculares constituyen una herramienta de gran utilidad a la hora de planificar las campañas de control vectorial, puesto que permiten conocer y…
Ashes from Sewage Sludge and Bottom Sediments as a Source of Bioavailable Phosphorus
2018
Phosphorus is an element necessary for the growth of plants. As phosphate rock gets depleted, it becomes an increasingly scarce resource. Therefore, it seems necessary to implement simple methods of cheap and effective phosphorus recovery from waste. The ashes of municipal sewage sludge and bottom sediments constitute particularly valuable sources of phosphorus. However, these materials usually carry significant amounts of pollutants, including heavy metals. Optimization of ash phosphorus sequential extraction methods from a thermal conversion of sewage sludge and bottom sediments allows to select an effective and simple technology of phosphorus recovery, while maintaining low heavy metal p…
Performance of polyester-based electrospun scaffolds under in vitro hydrolytic conditions: From short-term to long-term applications
2019
The evaluation of the performance of polyesters under in vitro physiologic conditions is essential to design scaffolds with an adequate lifespan for a given application. In this line, the degradation-durability patterns of poly(lactide-co-glycolide) (PLGA), polydioxanone (PDO), polycaprolactone (PCL) and polyhydroxybutyrate (PHB) scaffolds were monitored and compared giving, as a result, a basis for the specific design of scaffolds from short-term to long-term applications. For this purpose, they were immersed in ultra-pure water and phosphate buffer solution (PBS) at 37 °
L?atribució hipotètica de Curial e Güelfa a Enyego d?Àvalos (Consideracions sobre un «informe» de L. Badia i J. Torró)
2017
Resum: La revista Estudis Romanics 39 (2017) ha publicat el meu article: “Enyego d’Avalos, autor del Curial e Guelfa ?”, que resumeix una part de la meua tesi doctoral, La cort napolitana d’Alfons el Magnanim: el context del «Curial e Guelfa» (Universitat de Valencia, 2016). L’article defensa la hipotesi que Enyego d’Avalos –natural de Toledo, educat a Valencia, conseller de Felip Maria Visconti i gran camarlenc d’Alfons el Magnanim, al regne de Napols– hauria estat l’autor de la novel·la cavalleresca anonima Curial e Guelfa . Encara que la tesi es inedita, Lola Badia i Jaume Torro s’han manifestat en contra de la hipotesi mitjancant declaracions difamatories en mitjans de comunicacio i un …
A new design problem in the formulation of a special moment resisting connection device for preventing local buckling
2021
In the present paper an improved formulation devoted to the optimal design problem of a special moment resisting connection device for steel frames is proposed. This innovative device is called a Limited Resistance Plastic Device (LRPD) and it has been recently proposed and patented by some of the authors. It is thought to be preferably located at the extremes of the beam, connecting the beam end cross section with the relevant column. The typical device is a steel element characterized by symmetry with respect to three orthogonal barycentric planes and constituted by a sequence of three portions with abrupt cross section changes. The main novelty of the present proposal is related to the d…
Mechanical Tests on Innovative BIPV Façade Components for Energy, Seismic, and Aesthetic Renovation of High-Rise Buildings
2018
The paper shows the results of mechanical tests carried out on prototypes of a new Building Integrated Photovoltaic (BIPV) component developed by the author and SBskin Smart Building Skin s.r.l. This patented innovative component is able to merge structural function, insulation proprieties, and production of clean energy for retrofit actions and/or the construction of translucent faç
A Comparative Study on Nickel Binding to Hpn-like Polypeptides from Two Helicobacter pylori Strains
2021
Combined potentiometric titration and isothermal titration calorimetry (ITC) methods were used to study the interactions of nickel(II) ions with the N-terminal fragments and histidine-rich fragments of Hpn-like protein from two Helicobacter pylori strains (11637 and 26695). The ITC measurements were performed at various temperatures and buffers in order to extract proton-independent reaction enthalpies of nickel binding to each of the studied protein fragments. We bring up the problem of ITC results of nickel binding to the Hpn-like protein being not always compatible with those from potentiometry and MS regarding the stoichiometry and affinity. The roles of the ATCUN motif and multiple His…