Search results for "D1"
showing 10 items of 3056 documents
Bcl-xL as a Modulator of Senescence and Aging
2021
Many features of aging result from the incapacity of cells to adapt to stress conditions. When cells are overwhelmed by stress, they can undergo senescence to avoid unrestricted growth of damaged cells. Recent findings have proven that cellular senescence is more than that. A specific grade of senescence promotes embryo development, tissue remodeling and wound healing. However, constant stresses and a weakening immune system can lead to senescence chronicity with aging. The accumulation of senescent cells is directly related to tissue dysfunction and age-related pathologies. Centenarians, the most aged individuals, should accumulate senescent cells and suffer from their deleterious effects,…
Forme della negoziazione politica nel regno di Sicilia fra Trecento e Quattrocento
2005
Analisi delle forme della contrattazione politica fra corpi cittadini e monarchia nel regno di Sicilia del XIV e XV secolo attraverso la documentazione dei "capitoli" presentati a Corte. Si descrive la tipologia della fonte e il suo addensarsi attorno agli anni delle trasformazioni istituzionali e politiche a cavallo dei due secoli; si analizzano linguaggii e protagonisti della contrattazione, si identificano i punti fondamentali del negoziato permanente fra i due poteri del regno.
"Antavat anteeksi ovenvieret" : Matjoi Plattosen kuolinriittikuvaukset siirtymäriittiteorian valossa
2019
Tässä tutkimuksessa tarkastellaan suistamolaiselta itkijältä Matjoi Plattoselta vuosina 1908−1920 tallennettuja kuolinrituaalien kuvauksia ja niihin liittyviä itkuvirsiä siirtymäriittiteorian avulla. Tutkimuksen aineiston Plattosen kanssa ovat tuottaneet Matti Kaisla, U. T. Sirelius ja A. O. Väisänen. Tutkimuksessa kiinnitetään huomiota erityisesti rituaalisen itkemisen merkitykseen kuolinrituaalien osana. Yksilön tai ryhmän sosiaalisen kategorisen muutoksen yleismaailmallisesti kolmeen vaiheeseen jakavan siirtymäriittiteorian kehitti etnologi Arnold van Gennep (1873−1957). Hän väitti, että rituaaliset seremoniat, jotka liittyvät ihmiselämän tärkeimpiin muutoksiin, eroavat toisistaan eri ku…
Study of the Stability of Citrate Capped AgNPs in Several Environmental Water Matrices by Asymmetrical Flow Field Flow Fractionation
2021
Asymmetrical flow field-flow fractionation (AF4) coupled to UV-Vis and dynamic light scattering (DLS) detectors in series, was tested for stability studies of dispersions of citrate-capped silver nanoparticles (AgNPs) in several water matrices. The main goal is to provide knowledge to understand their possible behavior in the environment for short times since mixturing (up to 180 min). Ultrapure (UPW), bottled (BW1, BW2), tap (TW), transitional (TrW) and sea water (SW) matrices were assayed. Observations were compatible with the aggregation of AgNPs, a change in the plasmon band and a size growth with time were done. Fractograms showed different evolution fingerprints in the function of the…
Pulicaria glutinosa Extract: A Toolbox to Synthesize Highly Reduced Graphene Oxide-Silver Nanocomposites
2015
A green, one-step approach for the preparation of graphene/Ag nanocomposites (PE-HRG-Ag) via simultaneous reduction of both graphene oxide (GRO) and silver ions using Pulicaria glutinosa plant extract (PE) as reducing agent is reported. The plant extract functionalizes the surfaces of highly reduced graphene oxide (HRG) which helps in conjugating the Ag NPs to HRG. Increasing amounts of Ag precursor enhanced the density of Ag nanoparticles (NPs) on HRG. The preparation of PE-HRG-Ag nanocomposite is monitored by using ultraviolet-visible (UV-Vis) spectroscopy, powder X-ray diffraction (XRD), and energy dispersive X-ray (EDX). The as-prepared PE-HRG-Ag nanocomposities display excellent surfac…
Sindrome di Sotos: descrizione di un caso da ampia delezione del gene NSD1
2008
Zinc Adsorption by Activated Carbon Prepared from Lignocellulosic Waste Biomass
2019
Sawdust was used as a precursor for the production of biomass-based activated carbon. Carbonization and activation are single-stage processes, and steam was used as a physical activation agent at 800 °
Hopes and Limits of Adipose-Derived Stem Cells (ADSCs) and Mesenchymal Stem Cells (MSCs) in Wound Healing
2020
Adipose tissue derived stem cells (ADSCs) are mesenchymal stem cells identified within subcutaneous tissue at the base of the hair follicle (dermal papilla cells), in the dermal sheets (dermal sheet cells), in interfollicular dermis, and in the hypodermis tissue. These cells are expected to play a major role in regulating skin regeneration and aging-associated morphologic disgraces and structural deficits. ADSCs are known to proliferate and differentiate into skin cells to repair damaged or dead cells, but also act by an autocrine and paracrine pathway to activate cell regeneration and the healing process. During wound healing, ADSCs have a great ability in migration to be recruited rapidly…
Comparison of Machine Learning Methods in Stochastic Skin Optical Model Inversion
2020
In this study, we compare six different machine learning methods in the inversion of a stochastic model for light propagation in layered media, and use the inverse models to estimate four parameters of the skin from the simulated data: melanin concentration, hemoglobin volume fraction, and thicknesses of epidermis and dermis. The aim of this study is to determine the best methods for stochastic model inversion in order to improve current methods in skin related cancer diagnostics and in the future develop a non-invasive way to measure the physical parameters of the skin based partially on the results of the study. Of the compared methods, which are convolutional neural network, multi-layer …
On the use of composite indicators for mobile communications network management in smart sustainable cities
2020
Beyond 5G networks will be fundamental towards enabling sustainable mobile communication networks. One of the most challenging scenarios will be met in ultra-dense networks that are deployed in densely populated areas. In this particular case, mobile network operators should benefit from new assessment metrics and data science tools to ensure an effective management of their networks. In fact, incorporating architectures allowing a cognitive network management framework could simplify processes and enhance the network&rsquo