Search results for "D2O"

showing 10 items of 22 documents

A novel D2O tracer method to quantify RNA turnover as a biomarker of de novo ribosomal biogenesis, in vitro, in animal models, and in human skeletal …

2017

Current methods to quantify in vivo RNA dynamics are limited. Here, we developed a novel stable isotope (D2O) methodology to quantify RNA synthesis (i.e., ribosomal biogenesis) in cells, animal models, and humans. First, proliferating C2C12 cells were incubated in D2O-enriched media and myotubes ±50 ng/ml IGF-I. Second, rat quadriceps (untrained, n = 9; 7-wk interval-“like” training, n = 13) were collected after ~3-wk D2O (70 atom %) administration, with body-water enrichment monitored via blood sampling. Finally, 10 (23 ± 1 yr) men consumed 150-ml D2O followed by 50 ml/wk and undertook 6-wk resistance exercise (6 × 8 repetitions, 75% 1-repetition maximum 3/wk) with body-water enrichment mo…

0301 basic medicinePurineMaleSalivamedicine.medical_specialtyPhysiologymuscleEndocrinology Diabetes and MetabolismRiboseBiologyribosomal biogenesisCell LineQuadriceps Muscle03 medical and health scienceschemistry.chemical_compoundMiceYoung Adult0302 clinical medicineIn vivoTandem Mass SpectrometryPhysiology (medical)Internal medicinePhysical Conditioning AnimalmedicineAnimalsHumansNucleotideDeuterium OxideRNA synthesista315D2Ochemistry.chemical_classificationSkeletal muscleRNAResistance TrainingRibosomal RNARats030104 developmental biologymedicine.anatomical_structureEndocrinologychemistryInnovative MethodologyRNAFemaleRibosomes030217 neurology & neurosurgeryBiomarkersBlood samplingAmerican Journal of Physiology: Endocrinology and Metabolism
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ESR response to gamma-rays of alanine pellets containing B(OH)3 or Gd2O3.

2007

ESR response to gamma-irradiation (1-50 Gy) of blends containing alanine and either B(OH)(3) or Gd(2)O(3) is reported. The sensitivity of the alanine--B(OH)(3) blend is comparable to the sensitivity of pure alanine, although its lowest detectable dose, LDD, is smaller ( approximately 1.3 Gy) than that of pure alanine ( approximately 2.9 Gy). Alanine with Gd(2)O(3) is about two times more sensitive than pure alanine, and its LDD is 0.8 Gy. The better sensitivity and LDD are probably due to the high atomic number (Z=64) of gadolinium, which enhances the interaction probability with photons and, consequently, the radical yield. This study suggests that other high-Z atoms may be useful for incr…

AlanineHigh atomic numberRadiationAlanineGadoliniumRadiochemistryPelletsElectron Spin Resonance Spectroscopychemistry.chemical_elementGadoliniumESR; Alanine; B(OH)3; Gd2O3; Sensitivity; Mass energy absorption coefficientMass energy absorption coefficientSensitivitychemistryBoric AcidsIsotopesGd2O3Gamma RaysYield (chemistry)RadiometryB(OH)3ESRBoronApplied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine
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"Table 1" of "Photon electroproduction from hydrogen at backward angles and momentum transfer squared of Q**2 = 1.0-GeV**2."

2004

Cross section for the reaction E P --> E P GAMMA at a polar angle given by COS(THETA) = -0.975 and azimuthal angle PHI = 15 degrees both in the centre-of-mass frame of the GAMMA* P --> GAMMA* P reaction.

E- P --> E- P GAMMAElectron productionAstrophysics::High Energy Astrophysical PhenomenaExclusiveD5SIG/D2OMEGA/DPNuclear Experiment2.906
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"Table 17" of "Photon electroproduction from hydrogen at backward angles and momentum transfer squared of Q**2 = 1.0-GeV**2."

2004

Cross section for the reaction E P --> E P GAMMA at a polar angle given by COS(THETA) = -0.650 and azimuthal angle PHI = 135 degrees both in the centre-of-mass frame of the GAMMA* P --> GAMMA* P reaction.

E- P --> E- P GAMMAElectron productionAstrophysics::High Energy Astrophysical PhenomenaExclusiveD5SIG/D2OMEGA/DPNuclear Experiment2.906
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"Table 4" of "Photon electroproduction from hydrogen at backward angles and momentum transfer squared of Q**2 = 1.0-GeV**2."

2004

Cross section for the reaction E P --> E P GAMMA at a polar angle given by COS(THETA) = -0.975 and azimuthal angle PHI = 105 degrees both in the centre-of-mass frame of the GAMMA* P --> GAMMA* P reaction.

E- P --> E- P GAMMAElectron productionAstrophysics::High Energy Astrophysical PhenomenaExclusiveD5SIG/D2OMEGA/DPNuclear Experiment2.906
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"Table 12" of "Photon electroproduction from hydrogen at backward angles and momentum transfer squared of Q**2 = 1.0-GeV**2."

2004

Cross section for the reaction E P --> E P GAMMA at a polar angle given by COS(THETA) = -0.875 and azimuthal angle PHI = 165 degrees both in the centre-of-mass frame of the GAMMA* P --> GAMMA* P reaction.

E- P --> E- P GAMMAElectron productionAstrophysics::High Energy Astrophysical PhenomenaExclusiveD5SIG/D2OMEGA/DPNuclear Experiment2.906
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"Table 9" of "Photon electroproduction from hydrogen at backward angles and momentum transfer squared of Q**2 = 1.0-GeV**2."

2004

Cross section for the reaction E P --> E P GAMMA at a polar angle given by COS(THETA) = -0.875 and azimuthal angle PHI = 75 degrees both in the centre-of-mass frame of the GAMMA* P --> GAMMA* P reaction.

E- P --> E- P GAMMAElectron productionAstrophysics::High Energy Astrophysical PhenomenaExclusiveD5SIG/D2OMEGA/DPNuclear Experiment2.906
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"Table 7" of "Photon electroproduction from hydrogen at backward angles and momentum transfer squared of Q**2 = 1.0-GeV**2."

2004

Cross section for the reaction E P --> E P GAMMA at a polar angle given by COS(THETA) = -0.875 and azimuthal angle PHI = 15 degrees both in the centre-of-mass frame of the GAMMA* P --> GAMMA* P reaction.

E- P --> E- P GAMMAElectron productionAstrophysics::High Energy Astrophysical PhenomenaExclusiveD5SIG/D2OMEGA/DPNuclear Experiment2.906
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"Table 6" of "Photon electroproduction from hydrogen at backward angles and momentum transfer squared of Q**2 = 1.0-GeV**2."

2004

Cross section for the reaction E P --> E P GAMMA at a polar angle given by COS(THETA) = -0.975 and azimuthal angle PHI = 165 degrees both in the centre-of-mass frame of the GAMMA* P --> GAMMA* P reaction.

E- P --> E- P GAMMAElectron productionAstrophysics::High Energy Astrophysical PhenomenaExclusiveD5SIG/D2OMEGA/DPNuclear Experiment2.906
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"Table 3" of "Photon electroproduction from hydrogen at backward angles and momentum transfer squared of Q**2 = 1.0-GeV**2."

2004

Cross section for the reaction E P --> E P GAMMA at a polar angle given by COS(THETA) = -0.975 and azimuthal angle PHI = 75 degrees both in the centre-of-mass frame of the GAMMA* P --> GAMMA* P reaction.

E- P --> E- P GAMMAElectron productionAstrophysics::High Energy Astrophysical PhenomenaExclusiveD5SIG/D2OMEGA/DPNuclear Experiment2.906
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