Search results for "DAC"
showing 10 items of 1529 documents
Role of neurophysiology in the clinical practice of primary pediatric headaches
2007
The role of electrophysiological studies in pediatric headaches is controversial. In childhood headaches, neurophysiological examinations are of interest for potential clinical use because they are noninvasive and are scarcely influenced by environmental factors or drug use. Electrophysiological studies in childhood headache principally explored the role of electroencephalographic (EEG) evaluations in migraine, while less evidence has been reported about other neurophysiological techniques, such as evoked potentials, event-related potentials, and, less often, transcranial magnetic stimulation. In this brief review, we point out our attention to the aid of neurophysiological methods in the c…
Evaluation of endovenous sedation using BIS monitoring in dentistry. A systematic review
2018
Background The aim of the present review was evaluate the utility and validity of the Bispectral Index (BIS) in dental treatment carried out under endovenous sedation, and compare its efficacy with clinical sedation scales. Material and Methods Electronic and manual literature searches were conducted by two independent reviewers for articles published up to April 2017 in several databases, including Medline and Cochrane Library. Results Sixteen articles met the inclusion criteria. A correlation was identified between BIS and clinical sedation scales. A BIS range between 75 and 84 showed a high probability of corresponding to an Observer’s Assessment of Alertness and Sedation Scale (OAA/S) v…
Differential regulation of hexameric and dodecameric hemocyanin from A. leptodactylus
2013
The oxygen binding properties of hemocyanins are regulated on a short time scale by effectors such as l-lactate, urate and protons, and on longer time scales by expression of the different types of subunits. For Astacus leptodactylus it was shown previously that acclimation to higher temperatures leads to increased levels of a 6-meric hemocyanin species, whereas at lower temperatures the 12-meric form prevails. Here we show that the temperature dependence of the two forms supports the idea, that the maintenance of high affinity towards oxygen is the driving force for the differential expression of these hemocyanins. Furthermore, the two different types of hemocyanin differ not only in the a…
DAC 6, efficacia dell’accertamento tributario e trasparenza: fino a che punto sono legittimi i doveri di disclosure?
2021
I molteplici interventi sull’originaria struttura della direttiva DAC hanno comportato un notevole ampliamento degli obblighi di informazione fiscalmente rilevanti tanto sotto il profilo soggettivo (ampliamento della platea degli obbligati), quanto sotto quello oggettivo (ampliamento degli obblighi). Ciò induce, in prima battuta, a chiedersi quali possano essere i beni o interessi giuridici tutelati dallo scambio automatico di informazioni fiscalmente rilevanti nel contesto internazionale. Ma induce altresì a domandarsi entro quale misura la tutela di quei beni ed interessi possa legittimare un obbligo di disclosure che attiene non ad un piano domestico dei rapporti fra l’obbligato ed il pr…
Efectos de la modulación colinérgica y la administración de R-(+)-8-OH-DPAT sobre la evitación inhibitoria a lo largo del ciclo vital en ratones
2015
Las sustancias que actúan modulando los sistemas de neurotrasmisión colinérgico y serotoninérgico, como algunos antidepresivos, han demostrado en estudios previos un efecto deteriorante o facilitador en el aprendizaje y memoria de la tarea de evitación inhibitoria en roedores. Este trabajo tuvo como objetivo el investigar el papel que los sistemas de neurotrasmisión colinérgico y serotoninérgico a través de la administración de diferentes sustancias juegan en la consolidación del aprendizaje de evitación inhibitoria a lo largo de tres etapas del ciclo vital de ratones machos y hembras. Para ello se emplearon fármacos más específicos que interfieren en estos dos sistemas para analizar el efe…
Pobudzanie przez czytanie, czyli biblioterapia w pracy nauczyciela, wychowawcy, terapeuty
2017
W artykule zaprezentowana została biblioterapia jako metoda mająca zastosowanie w szerokim procesie edukacyjnym. Autorka stara się wykazać, że współczesna szkoła, będąca w przededniu reformy, powinna czerpać z dotychczasowych doświadczeń oraz osiągnięć neurodydaktyki. Opisane zostały sposoby wykorzystania biblioterapii jako metody rozwijającej wiedzę o świecie społecznym czytelnika. Ma ona również zastosowanie w rewalidacji jako metoda odpowiadająca na potrzeby rozwojowe dzieci i niepełnosprawnej młodzieży. Książka ma też znaczenie w poszukiwaniu i budowaniu poczucia sensu życia, szczególnie w przypadku osób o ograniczonej sprawności. Celem artykułu jest także ukazanie wychowawczych i terap…
The Subjective Social Value of Education Construct: CrossValidation between School and University Teachers
2016
La Educación posee un valor social evidente que puede presentarse mediante indicadores de evaluación socio-educativos. Si bien la relación entre contexto escolar y rendimiento es evidente en diversos países, esta relación va perdiendo consistencia en los últimos años; ya que aparecen sectores estudiantiles que superan las predicciones académicas esperadas. Para ello, se estudia el Valor Social Subjetivo de la Educación en función de dos grupos docentes –escuela y universidad–. La metodología es complementaria a través de comités de expertos/as y validación cruzada de constructo. Se realizan análisis sobre dos escalas –relevancia y susceptibilidad de cambio– y entre dos muestras diferenciada…
Poly(I:C) and CpG-ODN combined aerosolization to treat lung metastases and counter the immunosuppressive microenvironment.
2015
The immunostimulatory ability of synthetic oligonucleotides containing CpG motifs (CpG-ODN), agonists of Toll-like receptor 9 (TLR9), can be harnessed to promote antitumor immunity by their application at the tumor site to stimulate local activation of innate immunity; however, particularly in the lung, tumor-associated immunosuppression can subvert such antitumor innate immune responses. To locally maintain continuous activation of innate subpopulations while inhibiting immunosuppressive cells, we evaluated aerosol delivery CpG-ODN combined with Poly(I:C), a TLR3 agonist able to convert tumor-supporting macrophages to tumoricidal effectors, in the treatment of B16 melanoma lung metastases …
Anxiety disorder, depression and chronic daily headache: a case-control study.
2012
Chronic headache cause high disability in sufferers and high social cost. Data regarding possible comorbid diseases, manly depression and anxiety, are still few and conflicting.The aim of this case-control, hospital-based study was: to evaluate the prevalence of depression and anxiety in subjects with chronic migraine (CM) and chronic tension-type headache (CTTH); and to compare the results with those found in a control group without headache. Materials and methods We studied 79 patients, 46 with CM and 33 with CTTH, consecutively referred to the Adult Headache Centre of the University of Palermo (A.H. Study) between 2007 and 2009, and 316 controls without headache (each patient was matched…